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Byungju Chae

Sungkyunkwan University · 生化学・遺伝学・分子生物学

研究室紹介

Professor Byungju Chae's research lab specializes in clinical oncology and nuclear medicine, with a strong focus on improving cancer diagnosis, risk stratification, and patient-centered care. The lab investigates incidental findings in medical imaging—particularly in FDG-PET/CT—to assess cancer risk, with a particular emphasis on thyroid and breast cancers. Research also explores molecular subtypes of breast cancer, patterns of distant recurrence, and predictive biomarkers such as androgen receptor and DAX-1 to guide personalized treatment strategies. The lab integrates clinical, radiological, and pathological data to enhance diagnostic accuracy and patient outcomes.

breast cancerPET/CTthyroid cancermolecular subtypesoncology biomarkers

Research Overview

Papers
196
Total Citations
2,130
Papers (5y)
85
Primary Field
生化学・遺伝学・分子生物学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
85total
2022
2023
2024
2025
2026
Citations per year (5y)
315total
20222023202420252026

Selected Papers

15
1
Article|117 citations·2009
Incidental thyroid lesions detected by FDG-PET/CT: prevalence and risk of thyroid cancer
Ja Seong Bae, Byung Joo Chae, Woo Chan Park, Jeong Soo Kim, Sung Hoon Kim, Sang Seol Jung, Byung Joo Song
SJR Q1World Journal of Surgical OncologyOA

BACKGROUND: Incidentally found thyroid lesions are frequently detected in patients undergoing FDG-PET/CT. The aim of this study was to investigate the prevalence of incidentally found thyroid lesions in patients undergoing FDG-PET/CT and determine the risk for thyroid cancer. METHODS: FDG-PET/CT was performed on 3,379 patients for evaluation of suspected or known cancer or cancer screening without any history of thyroid cancer between November 2003 and December 2005. Medical records related to t

Endocrinology, Diabetes and MetabolismMedicine
2
Article|54 citations·2019
Unmet needs and related factors of Korean breast cancer survivors: a multicenter, cross-sectional study
Byung Joo Chae, Jihyoun Lee, Se Kyung Lee, Hyuk-Jae Shin, So‐Youn Jung, Jong Won Lee, Zisun Kim, Min Hyuk Lee, Ju Hyung Lee, Hyun Jo Youn
SJR Q2BMC CancerOA

BACKGROUND: Identification of specific needs in patients with cancer is very important for the provision of patient-centered medical service. The aim of this study was to investigate the unmet needs and related factors of Korean breast cancer survivors. METHODS: A multicenter, cross-sectional, interview survey was performed among 332 Korean breast cancer survivors. The Comprehensive Needs Assessment Tool for cancer patients was administered to survivors who gave written informed consent to parti

OncologyMedicine
3
Article|52 citations·2009
Predictive factors for breast cancer in patients diagnosed atypical ductal hyperplasia at core needle biopsy
Byung Joo Chae, Ahwon Lee, Byung Joo Song, Sang Seol Jung
SJR Q1World Journal of Surgical OncologyOA

BACKGROUND: Percutaneous core needle biopsy (CNB) is considered to be the standard technique for histological diagnosis of breast lesions. But, it is less reliable for diagnosing atypical ductal hyperplasia (ADH). The purpose of the present study was to predict, based on clinical and radiological findings, which cases of ADH diagnosed by CNB would be more likely to be associated with a more advanced lesion on subsequent surgical excision. METHODS: Between February 2002 and December 2007, consecu

Pathology and Forensic MedicineMedicine
4
Article|45 citations·2012
Pattern of distant recurrence according to the molecular subtypes in Korean women with breast cancer
Hyung Seok Park, Shin-Hyuk Kim, Ki‐Ho Kim, Ho Yoo, Byung Joo Chae, Ja Seong Bae, Byung Joo Song, Sang Seol Jung
SJR Q1World Journal of Surgical OncologyOA

BACKGROUND: Distant recurrence is one of the most important risk factors in overall survival, and distant recurrence is related to a complex biologic interaction of seed and soil factors. The aim of the study was to investigate the association between the molecular subtypes and patterns of distant recurrence in patients with breast cancer. METHODS: In an investigation of 313 women with breast cancer who underwent surgery from 1994 and 2000, the expressions of estrogen and progestrone receptor (E

Cancer ResearchBiochemistry, Genetics and Molecular Biology
5
Article|44 citations·2014
Correlation between obesity and clinicopathological factors in patients with papillary thyroid cancer
Shin-Hyuk Kim, Hyung Seok Park, Ki-Ho Kim, Ho Yoo, Byung‐Joo Chae, Ja Seong Bae, Sang-Seol Jung, Byung‐Joo Song
SJR Q2Surgery TodayOA
Endocrinology, Diabetes and MetabolismMedicine
6
Article|37 citations·2011
Performing Contralateral Central Lymph Node Dissection in Papillary Thyroid Carcinoma: A Decision Approach
Byung Joo Chae, Chan Kwon Jung, Dong Jun Lim, Byung Joo Song, Jeong Soo Kim, Sang Seol Jung, Ja Seong Bae
SJR Q1Thyroid

In patients with unilateral PTC, routine ipsilateral CLND with intraoperative reading of the frozen section can be employed to assess the risk of contralateral CLN metastasis. This information should be of value in deciding whether to perform contralateral CLND or not.

Endocrinology, Diabetes and MetabolismMedicine
7
Article|28 citations·2013
Effect of Axillary Lymph Node Dissection after Sentinel Lymph Node Biopsy on Overall Survival in Patients with T1 or T2 Node-positive Breast Cancer: Report from the Korean Breast Cancer Society
Korea Breast Cancer Society, Hyung Seok Park, Byung Joo Chae, Byung Joo Song, Sang Seol Jung, Wonshik Han, Seok Jin Nam, Hyun Jo Youn, Byung Kyun Ko, Dong Wook Kim
SJR Q1Annals of Surgical OncologyOA
Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
Article|25 citations·2020
Axillary lymph node dissection is not obligatory in breast cancer patients with biopsy-proven axillary lymph node metastasis
Tae-Kyung Yoo, Bong Joo Kang, Sung Hun Kim, Byung Joo Song, Juneyoung Ahn, Woo Chan Park, Byung Joo Chae
SJR Q1Breast Cancer Research and Treatment
Cancer ResearchBiochemistry, Genetics and Molecular Biology
9
Article|24 citations·2017
Identifying long-term survivors among metastatic breast cancer patients undergoing primary tumor surgery
Tae-Kyung Yoo, Byung Joo Chae, Sei Joong Kim, Jung Sun Lee, Tae In Yoon, Soo Jung Lee, Ho Yong Park, Heung Kyu Park, Yong Hwa Eom, Hyung‐Suk Kim, Chang Jong Kim, Man Sik Shin
SJR Q1Breast Cancer Research and Treatment
Cancer ResearchBiochemistry, Genetics and Molecular Biology
10
Article|23 citations·2011
Expression of nuclear receptor DAX‐1 and androgen receptor in human breast cancer
Byung Joo Chae, Ahwon Lee, Ja Seong Bae, Byung Joo Song, Sang Seol Jung
SJR Q1Journal of Surgical Oncology

BACKGROUND: The functions of nuclear receptor DAX-1 and androgen receptor (AR) in breast cancer are unknown and have not been well-characterized in terms of their importance as a predictive or a prognostic factor. The study investigated the relationship between expression of AR, DAX-1, and clinicopathological factors in primary breast cancer patients. METHODS: The data of 476 breast cancer patients who were treated at Seoul St. Mary's hospital from January 2004 to March 2006 were reviewed. Among

GeneticsBiochemistry, Genetics and Molecular Biology
11
Article|17 citations·2015
The distance between breast cancer and the skin is associated with axillary nodal metastasis
Yong Hwa Eom, Eun Jin Kim, Byung Joo Chae, Byung Joo Song, Sang Seol Jung
SJR Q1Journal of Surgical Oncology

BACKGROUND AND OBJECTIVES: More superficially located tumors may be more likely than deeper tumors to metastasize to the axillary nodes via the lymphatics. The aim of this study was to determine whether breast cancer distance from the skin affects axillary node metastasis, ipsilateral breast cancer recurrence, or recurrence-free survival. MATERIALS AND METHODS: A total of 1,005 consecutive patients with breast cancer who underwent surgery between January 2003 and December 2009 were selected. The

Cancer ResearchBiochemistry, Genetics and Molecular Biology
12
Article|15 citations·2022
A triple-negative breast cancer surrogate subtype classification that correlates with gene expression subtypes
Tae-Kyung Yoo, Jun Kang, A-Won Lee, Byung Joo Chae
SJR Q1Breast Cancer Research and Treatment
Cancer ResearchBiochemistry, Genetics and Molecular Biology
13
Article|14 citations·2020
Breast radiologic complete response is associated with favorable survival outcomes after neoadjuvant chemotherapy in breast cancer
Jinsun Woo, Jai Min Ryu, Sung Mi Jung, Hee Jun Choi, Se Kyung Lee, Jonghan Yu, Jeong Eon Lee, Seok Won Kim, Seok Jin Nam, Byung Joo Chae
SJR Q1European Journal of Surgical Oncology
Cancer ResearchBiochemistry, Genetics and Molecular Biology
14
Article|13 citations·2013
Feasibility of sentinel lymph node biopsy in breast cancer patients clinically suspected of axillary lymph node metastasis on preoperative imaging
Hee Yong Kwak, Byung Joo Chae, Ja Seong Bae, Eun Jin Kim, Eun Young Chang, Sang Hoon Kim, Sang Seol Jung, Byung Joo Song
SJR Q1World Journal of Surgical OncologyOA

BACKGROUND: Generally, sentinel lymph node biopsy (SLNB) is performed in patients with clinically negative axillary lymph node (LN). This study was to assess imaging techniques in axillary LN staging and to evaluate the feasibility of SLNB in patients clinically suspected of axillary LN metastasis on preoperative imaging techniques (SI). METHODS: A prospectively maintained database of 767 breast cancer patients enrolled between January 2006 and December 2009 was reviewed. All patients were offer

Cancer ResearchBiochemistry, Genetics and Molecular Biology
15
Article|12 citations·2023
The Impact of HER2-Low Expression on Oncologic Outcomes in Hormone Receptor-Positive Breast Cancer
Woong Ki Park, Seok Jin Nam, Seok Won Kim, Jeong Eon Lee, Jonghan Yu, Jai Min Ryu, Byung Joo Chae
SJR Q1CancersOA

Breast cancer is a prevalent malignancy with increasing incidence, particularly in Asian countries. Classification based on estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) status is pivotal in determining treatment. Recent advances have challenged the traditional dichotomy in HER2 classification, prompting investigation into the HER2-low subtype’s characteristics and outcomes. This retrospective study analyzed 10,186 non-metastatic hormone

OncologyMedicine

Research Areas

Cancer ResearchOncologySurgeryGeneticsEndocrinology, Diabetes and MetabolismPulmonary and Respiratory Medicine

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