Skip to main content

Chae Jung Park

Yonsei University · 医学

研究室紹介

Professor Chae Jung Park's research lab specializes in neuroimaging and biomarker discovery in neurodegenerative and neurological disorders, with a focus on integrating advanced medical imaging techniques—such as MRI, DTI, and EEG—with machine learning and radiomics to improve early diagnosis and prognosis prediction. The lab investigates brain network alterations, glymphatic system function, and epileptiform activity (e.g., high-frequency oscillations) in conditions like Parkinson’s disease, dementia, gliomas, and epilepsy. A key emphasis is on translating these imaging-based biomarkers into clinically actionable tools through adherence to rigorous reporting standards and validation frameworks.

neuroimagingbrain biomarkersmachine learningglymphatic systemepilepsy biomarkers

Research Overview

Papers
49
Total Citations
617
Papers (5y)
30
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
30total
2022
2023
2024
2025
2026
Citations per year (5y)
335total
20222023202420252026

Selected Papers

15
1
Article|58 citations·2023
Association between choroid plexus volume and cognition in Parkinson disease
Seong Ho Jeong, Hyun-Jae Jeong, Mun Kyung Sunwoo, Sung Soo Ahn, Seung‐Koo Lee, Phil Hyu Lee, Yun Joong Kim, Young H. Sohn, Chae Jung Park, Seok Jong Chung
SJR Q1European Journal of NeurologyOA

BACKGROUND AND PURPOSE: The choroid plexus (CP) clears harmful metabolites from the central nervous system as part of the glymphatic system. We investigated the association of CP volume (CPV) with baseline and longitudinal cognitive decline in patients with Parkinson disease (PD). METHODS: We retrospectively reviewed the medical records of 240 patients with newly diagnosed PD who had undergone detailed neuropsychological tests and high-resolution T1-weighted structural magnetic resonance imaging

Cellular and Molecular NeuroscienceNeuroscience
2
Article|50 citations·2021
MRI Features May Predict Molecular Features of Glioblastoma in Isocitrate Dehydrogenase Wild-Type Lower-Grade Gliomas
Chae Jung Park, Kyunghwa Han, Hwiyoung Kim, Sung Soo Ahn, Dongmin Choi, Yae Won Park, Jong Hee Chang, Se Hoon Kim, Soonmee Cha, Seung‐Koo Lee
SJR Q1American Journal of NeuroradiologyOA

MR imaging features integrated with machine learning classifiers may predict a subset of <i>IDH</i> wild-type lower-grade gliomas that carry molecular features of glioblastoma.

Radiology, Nuclear Medicine and ImagingMedicine
3
Article|43 citations·2019
Diffusion tensor imaging radiomics in lower-grade glioma: improving subtyping of isocitrate dehydrogenase mutation status
Chae Jung Park, Yoon Seong Choi, Yae Won Park, Sung Soo Ahn, Seok‐Gu Kang, Jong Hee Chang, Se Hoon Kim, Seung‐Koo Lee
SJR Q1NeuroradiologyOA
GeneticsMedicine
4
Article|30 citations·2022
Quality of Radiomics Research on Brain Metastasis: A Roadmap to Promote Clinical Translation
Chae Jung Park, Yae Won Park, Sung Soo Ahn, Dain Kim, Eui Hyun Kim, Seok‐Gu Kang, Jong Hee Chang, Se Hoon Kim, Seung‐Koo Lee
SJR Q1Korean Journal of RadiologyOA

The overall scientific and reporting quality of radiomics studies on brain metastases published during the study period was insufficient. Radiomics studies should adhere to the RQS, TRIPOD, and IBSI guidelines to facilitate the translation of radiomics into the clinical field.

Radiology, Nuclear Medicine and ImagingMedicine
5
Article|26 citations·2023
Evaluation of glymphatic system activity using diffusion tensor image analysis along the perivascular space and amyloid PET in older adults with objectively normal cognition: a preliminary study
Chae Jung Park, Sang‐Young Kim, Jun Hwee Kim, Nak‐Hoon Son, Jin Young Park, Jin Young Park, Yong Hyu Jeong, Hyun Jeong Kim, Jaesub Park, Jaesub Park, Woo Jung Kim
SJR Q1Frontiers in Aging NeuroscienceOA

Objectives Diffusion tensor image analysis along the perivascular space (DTI-ALPS) is a recently introduced method for the assessment of the glymphatic system without the need for contrast injection. The purpose of our study was to assess the glymphatic system in cognitively normal older adults with or without subjective cognitive decline (SCD) using DTI-ALPS, and correlating with amyloid PET. Design and participants To evaluate the glymphatic system in cognitively normal older adults using DTI-

Cellular and Molecular NeuroscienceNeuroscience
6
Article|25 citations·2016
Reliability of Breast Ultrasound BI-RADS Final Assessment in Mammographically Negative Patients with Nipple Discharge and Radiologic Predictors of Malignancy
Chae Jung Park, Eun‐Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Min Jung Kim
SJR Q2Journal of Breast CancerOA

PURPOSE: The purpose of this study was to retrospectively investigate the reliability of breast ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) final assessment in mammographically negative patients with pathologic nipple discharge, and to determine the clinical and ultrasonographic variables associated with malignancy in this group of patients.\n\nMETHODS: A total of 65 patients with 67 mammographically negative breast lesions that were pathologically confirmed through US-gui

Pathology and Forensic MedicineMedicine
7
Article|18 citations·2023
An interpretable multiparametric radiomics model of basal ganglia to predict dementia conversion in Parkinson’s disease
Chae Jung Park, Jihwan Eom, Ki Sung Park, Yae Won Park, Seok Jong Chung, Yun Joong Kim, Sung Soo Ahn, Jinna Kim, Phil Hyu Lee, Young H. Sohn, Seung‐Koo Lee
SJR Q1npj Parkinson s DiseaseOA

Cognitive impairment in Parkinson's disease (PD) severely affects patients' prognosis, and early detection of patients at high risk of dementia conversion is important for establishing treatment strategies. We aimed to investigate whether multiparametric MRI radiomics from basal ganglia can improve the prediction of dementia development in PD when integrated with clinical profiles. In this retrospective study, 262 patients with newly diagnosed PD (June 2008-July 2017, follow-up >5 years) were in

Radiology, Nuclear Medicine and ImagingMedicine
8
Article|18 citations·2020
Radiomics risk score may be a potential imaging biomarker for predicting survival in isocitrate dehydrogenase wild-type lower-grade gliomas
Chae Jung Park, Kyunghwa Han, Hwiyoung Kim, Sung Soo Ahn, Yoon Seong Choi, Yae Won Park, Jong Hee Chang, Se Hoon Kim, Rajan Jain, Seung‐Koo Lee
SJR Q1European RadiologyOA
GeneticsMedicine
9
Article|17 citations·2017
Management of subcentimetre arterially enhancing and hepatobiliary hypointense lesions on gadoxetic acid-enhanced MRI in patients at risk for HCC
Chae Jung Park, Chansik An, Sumi Park, Jin‐Young Choi, Myeong‐Jin Kim
SJR Q1European RadiologyOA
HepatologyMedicine
10
Article|16 citations·2022
An interpretable radiomics model to select patients for radiotherapy after surgery for WHO grade 2 meningiomas
Chae Jung Park, Seo Hee Choi, Jihwan Eom, Hwa Kyung Byun, Sung Soo Ahn, Jong Hee Chang, Se Hoon Kim, Seung‐Koo Lee, Yae Won Park, Hong In Yoon
SJR Q1Radiation OncologyOA

OBJECTIVES: This study investigated whether radiomic features can improve the prediction accuracy for tumor recurrence over clinicopathological features and if these features can be used to identify high-risk patients requiring adjuvant radiotherapy (ART) in WHO grade 2 meningiomas. METHODS: Preoperative magnetic resonance imaging (MRI) of 155 grade 2 meningioma patients with a median follow-up of 63.8 months were included and allocated to training (n = 92) and test sets (n = 63). After radiomic

EpidemiologyMedicine
11
Article|15 citations·2023
MRI radiomics may predict early tumor recurrence in patients with sinonasal squamous cell carcinoma
Chae Jung Park, Seo Hee Choi, Dain Kim, Si Been Kim, Kyunghwa Han, Sung Soo Ahn, Won Hee Lee, Eun Chang Choi, Ki Chang Keum, Jinna Kim
SJR Q1European Radiology
SurgeryMedicine
12
Article|15 citations·2018
Contrast-Enhanced CT with Knowledge-Based Iterative Model Reconstruction for the Evaluation of Parotid Gland Tumors: A Feasibility Study
Chae Jung Park, Ki Wook Kim, Ho‐Joon Lee, Myeong‐Jin Kim, Jinna Kim
SJR Q1Korean Journal of RadiologyOA

The purpose of this study was to determine the diagnostic utility of low-dose CT with knowledge-based iterative model reconstruction (IMR) for the evaluation of parotid gland tumors. Materials and Methods: This prospective study included 42 consecutive patients who had undergone low-dose contrastenhanced CT for the evaluation of suspected parotid gland tumors. Prior or subsequent non-low-dose CT scans within 12 months were available in 10 of the participants. Background noise (BN), signal-to-noi

SurgeryMedicine
13
Article|12 citations·2020
MR image phenotypes may add prognostic value to clinical features in IDH wild-type lower-grade gliomas
Chae Jung Park, Kyunghwa Han, Hae-Sol Shin, Sung Soo Ahn, Yoon Seong Choi, Yae Won Park, Jong Hee Chang, Se Hoon Kim, Rajan Jain, Seung‐Koo Lee
SJR Q1European RadiologyOA
GeneticsMedicine
14
Article|12 citations·2017
Thyroid Nodules With Nondiagnostic Cytologic Results: Follow-Up Management Using Ultrasound Patterns Based on the 2015 American Thyroid Association Guidelines
Chae Jung Park, Eun‐Kyung Kim, Hee Jung Moon, Jung Hyun Yoon, Vivian Youngjean Park, Jin Young Kwak
SJR Q1American Journal of RoentgenologyOA

When US findings of thyroid nodules are assessed according to the 2015 ATA guidelines, nondiagnostic thyroid nodules with very-low- or low-suspicion US patterns can be followed up with US. Nondiagnostic nodules with intermediate or highly suspicious US patterns should be evaluated with repeat US-guided fine-needle aspiration biopsy.

Endocrinology, Diabetes and MetabolismMedicine
15
Article|9 citations·2016
Reliability of Breast Ultrasound BI-RADS Final Assessment in Mammographically Negative Patients with Nipple Discharge and Radiologic Predictors of Malignancy
박채정, 김은경, 문희정, 윤정현, 김민정
Journal of Breast Cancer

Purpose: The purpose of this study was to retrospectively investigate the reliability of breast ultrasound (US) Breast Imaging Reporting and Data System (BI-RADS) final assessment in mammographically negative patients with pathologic nipple discharge, and to determine the clinical and ultrasonographic variables associated with malignancy in this group of patients. Methods: A total of 65 patients with 67 mammographically negative breast lesions that were pathologically confirmed through US-guided

Research Areas

Radiology, Nuclear Medicine and ImagingGeneticsCellular and Molecular NeurosciencePathology and Forensic MedicineSurgeryNeurology

Chae Jung Parkの研究をNubintでさらに深く

この研究室の論文をアプリで開き、AIと共に読み、要約し、引用しましょう。