Chan-kyo Kim
Sungkyunkwan University · 医学
研究室紹介
Professor Chan-kyo Kim's research lab specializes in diagnostic medical imaging, with a primary focus on prostate and liver cancer detection using advanced MRI techniques. The lab investigates the clinical utility of diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC) mapping, and dynamic contrast-enhanced MRI at 3T to improve the accuracy of cancer diagnosis, localization, and staging. Key research directions include optimizing b-values for DWI in prostate cancer, evaluating the incremental value of combined T2WI and DWI for detecting recurrent disease, and assessing ultrasonography for early detection of hepatocellular carcinoma in cirrhotic patients. The lab emphasizes quantitative imaging biomarkers to enhance preoperative planning and patient outcomes.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15DWI is a feasible technique that can be used for the differentiation of malignant and benign tissues in the PZ and TZ. Additionally, T2WI with DWI is superior to T2WI alone for the prediction of prostate cancer location.
Prostate DWI performed at 3 T using high b values was able to improve differentiation of tumors from benign tissue. DWI performed using a b value of 1,000 s/mm2 was more sensitive and more accurate in predicting localized prostate cancer than DWI performed using a b value of 2,000 s/mm2.
The purpose of this study was to assess the usefulness of ultrasonography in the detection of hepatocellular carcinomas and dysplastic nodules in patients with liver cirrhosis. Pretransplantation sonograms in 52 patients with liver cirrhosis who underwent orthotopic liver transplantation were evaluated retrospectively. The numbers of hepatocellular carcinomas and dysplastic nodules were assessed in the explanted liver specimens and compared with pretransplantation ultrasonographic results. Eight
PURPOSE: To prospectively evaluate the incremental value of diffusion-weighted imaging (DWI) with apparent diffusion coefficient (ADC) maps in addition to T2-weighted imaging (T2WI) for predicting locally recurrent prostate cancer in patients with biochemical failure after radiation therapy. MATERIALS AND METHODS: Thirty-six consecutive patients with an increased prostate-specific antigen level after radiation therapy underwent 3T MRI followed by transrectal biopsy. The MRI findings and biopsy r
Dynamic contrast-enhanced imaging at 3T MRI is superior to T2-weighted imaging for the detection and depiction of prostate cancer and thus is likely to be more useful for preoperative staging.
The DWI of the prostate at 3T MRI using a phased-array coil was useful for the differentiation of malignant and benign tissues in the TZ and PZ.
For prediction of local tumor progression of prostate cancer after high-intensity focused ultrasonic ablation, DCE-MRI was more sensitive than T2-weighted MRI with DWI, but T2-weighted MRI with DWI was more specific than DCE-MRI.
OBJECTIVE. The objective of this article is to review the basic concepts for the biologic basis of diffusion-weighted MRI (DWI), illustrate its potential clinical applications at 3 T, and discuss its current limitations and future directions.
The 3.0-T phased-array MRI is equivalent to the 1.5-T endorectal MRI in evaluating local staging accuracy for prostate cancer without significant loss of imaging quality.
On MRI, gossypiboma in the abdomen and pelvis manifested as a well-defined mass that showed a peripheral wall of low signal intensity at T1- and T2-weighted imaging and enhancement at contrast-enhanced T1-weighted imaging. The whorled stripes within the central portion were characteristically shown as low signal at T2-weighted imaging, and the serrated contour in the inner border of the peripheral wall was shown at contrast-enhanced T1-weighted imaging. Histopathologically, the peripheral wall s
DWI in addition to T2WI at 3 T has the potential to provide important information on lesion localization in patients that had both previous negative TRUS biopsy and persistently elevated prostate specific antigen levels before a repeated biopsy.
More recently, 3-T magnetic resonance (MR) scanner become more clinically available, and clinical application of 3-T MR imaging (MRI) of the abdomen and pelvis is now feasible and being performed at many institutions. However, few prostrate 3-T MRI studies have been published. The increase in signal-to-noise ratio at 3 versus 1.5 T clearly improves spatiotemporal and spectral resolutions of the prostate. Thus, we asked whether 3-T MRI improves the localization and staging of prostate cancer vers