Chang Kyu Lee
Yonsei University · 医学
研究室紹介
Professor Chang Kyu Lee's research lab specializes in cerebrovascular and neurosurgical disorders, with a primary focus on aneurysmal subarachnoid hemorrhage (SAH), particularly in poor-grade patients (Hunt and Hess Grade IV/V). The lab investigates surgical and medical management strategies to improve outcomes, evaluates complications such as delayed cerebral ischemia and post-dural puncture headache, and explores innovative techniques like endovascular aneurysm occlusion and microsurgical cysto-cisternal shunting. The research also extends to experimental models of inflammatory arthritis to assess the therapeutic potential of antioxidants like vitamin E.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15To formulate treatment strategies for poor-grade patients after aneurysmal subarachnoid hemorrhage (SAH), medical records were analyzed for 166 patients who were in Hunt and Hess Grade IV or V among 588 consecutive cases with ruptured intracranial aneurysm admitted during the past 5 years. Causes of unfavorable outcome (poor or dead) in those 166 patients were evaluated to improve the management outcome. Overall management results of the 166 poor-grade patients were favorable (good or fair) in 7
A case of fatal rupture of a giant internal carotid aneurysm is reported, which occurred after an extracranial to intracranial (EC-IC) bypass surgery combined with occlusion of the proximal internal carotid artery (ICA) by detachable balloons. A 65-year-old woman presented with progressive visual deterioration due to an unruptured giant aneurysm at the supraclinoid segment of the ICA. Since the patient did not tolerate a balloon occlusion test of the ICA, saphenous vein graft was undertaken betw
To establish a management strategies for poor-grade patients after aneurysmal subarachnoid hemorrhage (SAH), medical records were analyzed for 166 patients who were in Hunt and Hess Grade IV or V among 588 consecutive cases with ruptured intracranial aneurysm admitted during the past 5 years. Causes of unfavorable outcome (poor or dead) in those 166 patients were evaluated to improve the management outcome.Overall management results of the 166 poor-grade patients were favorable (good or fair) in
Intracranial arachnoid cysts are benign, thin-walled cysts characteristically lying in the arachnoid, filled with clear fluid, located in general near primary fissure of the cerebral cortex and cerebellum, and associated with varying degrees of cerebral tissue loss by compression. Although cystoperitoneal shunt surgery is indicated in some cases with the midline or the posterior fossa cysts, the rest of the arachnoid cysts are best managed by the radical microsurgical technique of establishing a
<i>Background: </i>In spinal saddle anesthesia, maintaining the sitting position for 3–5 min, to allow for the descent of the injected drug after lumbar dural puncture, minimizes side effects such as blood pressure reduction. However, it also increases cerebrospinal fluid leakage due to the hydrostatic pressure. We investigated the effects of the maintenance of the sitting position after spinal anesthesia on the development of postdural puncture headache (PDPH). <i>Methods: </i>We reviewed all d