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Chulho Sohn

Seoul National University · 医学

研究室紹介

Professor Chulho Sohn's research lab specializes in advanced neuroimaging techniques, particularly in the application of 3T MRI and perfusion imaging for the diagnosis and management of cerebrovascular diseases. The lab focuses on improving the accuracy of early detection for acute stroke, subarachnoid hemorrhage, and brain death using sequences such as SWI, GRE T2*, FLAIR, DWI, and arterial spin labeling (ASL). Key research directions include optimizing imaging protocols for timely diagnosis, understanding hemodynamic changes in acute ischemic stroke, and identifying radiologic markers that predict clinical outcomes after endovascular therapy.

neuroimagingacute strokeperfusion MRIsubarachnoid hemorrhage3T MRI

Research Overview

Papers
416
Total Citations
8,958
Papers (5y)
94
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
94total
2021
2022
2023
2024
2025
Citations per year (5y)
877total
20212022202320242025

Selected Papers

15
1
Article|71 citations·2003
Characteristic MR imaging findings of cavernous hemangiomas in the cavernous sinus.
Chul Ho Sohn, Sang Pyo Kim, Il‐man Kim, Jeong Hyun Lee, Ho Kyu Lee
PubMedOA

Cavernous hemangiomas occur very rarely in the cavernous sinus and are difficult to diagnose preoperatively. MR images obtained in five patients with surgically verified cavernous hemangiomas in the cavernous sinus were reviewed. MR images showed hypointensity on T1-weighted images and well-defined hyperintensity on T2-weighted images with marked homogeneous enhancement after contrast material administration. We report the characteristic MR imaging observations for these lesions.

NeurologyMedicine
2
Article|41 citations·2005
MR imaging of hyperacute subarachnoid and intraventricular hemorrhage at 3T: a preliminary report of gradient echo T2*-weighted sequences.
Chul‐Ho Sohn, Seung-Kug Baik, Hee-Jung Lee, Sung-Moon Lee, Il‐man Kim, Man-Bin Yim, Jae-Suk Hwang, M. Louis Lauzon, Robert J. Sevick
PubMedOA

We describe MR imaging findings applying gradient echo (GRE) T2*-weighted and fluid-attenuated inversion recovery (FLAIR) MR images at 3T to three patients with hyperacute subarachnoid and intraventricular hemorrhage from ruptured aneurysms. Hyperacute subarachnoid and intraventricular hemorrhages (SAH and IVH) were more clearly visualized as an area of decreased signal intensity on GRE T2*-weighted sequences than on FLAIR sequences in all three patients. These preliminary results suggest that a

Radiology, Nuclear Medicine and ImagingMedicine
3
Article|36 citations·2018
Impact of stroke mechanism in acute basilar occlusion with reperfusion therapy
Woo‐Jin Lee, Keun‐Hwa Jung, Young Jin Ryu, Jeong‐Min Kim, Soon‐Tae Lee, Kon Chu, Manho Kim, Sang Kun Lee, Chul‐Ho Sohn, Jae‐Kyu Roh
SJR Q1Annals of Clinical and Translational NeurologyOA

Abstract Objective We aimed to evaluate the impact of underlying mechanism of basilar artery ( BA ) occlusion on the outcomes after endovascular therapy ( EVT ) for reperfusion and the outcome factors associated with each mechanism, and to identify radiologic parameters enabling to distinguish the underlying mechanism. Methods From a registry database, 194 consecutive patients with acute BA occlusion who underwent EVT were analyzed. Stroke mechanism, classified into in situ atherosclerotic throm

EpidemiologyMedicine
4
Article|36 citations·2012
Imaging Findings of Brain Death on 3-Tesla MRI
Chul‐Ho Sohn, Hwa-Pyung Lee, Jun Beom Park, Hyuk Won Chang, Ealmaan Kim, Eunhee Kim, Ui Jun Park, Hyoung-Tae Kim, Jeonghun Ku
SJR Q1Korean Journal of RadiologyOA

T2-weighted imaging, DWI, and MRA using 3T MRI may be useful for diagnosing brain death. However, SWI findings are not specific due to high false positive findings.

Public Health, Environmental and Occupational HealthMedicine
5
Review|34 citations·2003
Contrast-enhanced MR angiography of the intracranial circulation
Chul‐Ho Sohn, Robert J. Sevick, Richard Frayne
SJR Q2Magnetic Resonance Imaging Clinics of North America
Radiology, Nuclear Medicine and ImagingMedicine
6
Article|33 citations·2013
Effect of Delayed Transit Time on Arterial Spin Labeling
Tae Jin Yun, Chul‐Ho Sohn, Moon Hee Han, Hyun‐Seung Kang, Jeong Eun Kim, Byung‐Woo Yoon, Jin Chul Paeng, Seung Hong Choi, Ji‐hoon Kim, In Chan Song, K H Chang
SJR Q1Investigative Radiology

Our results demonstrate that the correlation between the CBF values from the ASL and DSC tends to be weaker when the transit time is more delayed, with the restoration of the strength of the correlation when the TTP is extremely delayed (>25 seconds). Understanding the effect of delayed transit time on the CBF from ASL perfusion MR in a clinical setting would facilitate the proper interpretation of ASL images.

Radiology, Nuclear Medicine and ImagingMedicine
7
Article|30 citations·2012
Effect of carotid artery stenting on cerebral blood flow: evaluation of hemodynamic changes using arterial spin labeling
Tae Jin Yun, Chul‐Ho Sohn, Moon Hee Han, Byung‐Woo Yoon, Hyun‐Seung Kang, Jeong Eun Kim, Jin Chul Paeng, Seung Hong Choi, Ji‐hoon Kim, K H Chang
SJR Q1Neuroradiology
Pulmonary and Respiratory MedicineMedicine
8
Article|29 citations·2014
MRI molecular imaging using GLUT1 antibody-Fe3O4 nanoparticles in the hemangioma animal model for differentiating infantile hemangioma from vascular malformation
Chul‐Ho Sohn, Seung Pyo Park, Seung Hong Choi, Sung‐Hye Park, Sukwha Kim, Lianji Xu, Sang-Hyon Kim, Jian Hur, Jaehoon Choi, Tae Hyun Choi
SJR Q1Nanomedicine Nanotechnology Biology and Medicine
SurgeryMedicine
9
Article|29 citations·2020
Association of carotid and intracranial stenosis with Alzheimer’s disease biomarkers
Koung Mi Kang, Min Soo Byun, Jun Ho Lee, Dahyun Yi, Hye Jeong Choi, Eunjung Lee, Younghwa Lee, Jun‐Young Lee, Yu Kyeong Kim, Bo Kyung Sohn, Chul‐Ho Sohn, Dong Young Lee
SJR Q1Alzheimer s Research & TherapyOA

BACKGROUND: To clarify whether atherosclerosis of the carotid and intracranial arteries is related to Alzheimer's disease (AD) pathology in vivo, we investigated the associations of carotid and intracranial artery stenosis with cerebral beta-amyloid (Aβ) deposition and neurodegeneration in middle- and old-aged individuals. Given different variations of the pathologies between cognitive groups, we focused separately on cognitively normal (CN) and cognitively impaired (CI) groups. METHODS: C] Pitt

Psychiatry and Mental healthMedicine
10
Article|29 citations·2017
Detection of crossed cerebellar diaschisis in hyperacute ischemic stroke using arterial spin-labeled MR imaging
Koung Mi Kang, Chul‐Ho Sohn, Seung Hong Choi, Keun‐Hwa Jung, Roh‐Eul Yoo, Tae Jin Yun, Ji‐hoon Kim, Sun‐Won Park
SJR Q1PLoS ONEOA

ASL imaging could detect CCD in 75% of patients with hyperacute infarction. We found that CCD was more prevalent in patients with arterial occlusion, larger ischemic brain volumes, and higher initial NIHSS and mRS scores. In particular, vessel occlusion and initial mRS score appeared to be significantly related with CCD pathophysiology in the hyperacute stage.

EpidemiologyMedicine
11
Article|25 citations·2015
Evaluation of the degree of arteriovenous shunting in intracranial arteriovenous malformations using pseudo-continuous arterial spin labeling magnetic resonance imaging
Leonard Sunwoo, Chul‐Ho Sohn, Jong Young Lee, Kyung Sik Yi, Tae Jin Yun, Seung Hong Choi, Young Dae Cho, Ji‐hoon Kim, Sun‐Won Park, Moon Hee Han, Sun Ha Paek, Yong Hwy Kim
SJR Q1Neuroradiology
NeurologyMedicine
12
Article|25 citations·2017
Evaluation of Gadolinium Retention After Serial Administrations of a Macrocyclic Gadolinium-Based Contrast Agent (Gadobutrol)
Roh‐Eul Yoo, Chul‐Ho Sohn, Koung Mi Kang, Tae Jin Yun, Seung Hong Choi, Ji-hoon Kim, Sun‐Won Park
SJR Q1Investigative Radiology

OBJECTIVE: There has been controversy as to whether gadobutrol, one of the widely used macrocyclic gadolinium-based contrast agents, can lead to gadolinium retention after serial injections. Our aim was to validate whether serial administrations of gadobutrol can cause signal increase in the dentate nucleus (DN) and globus pallidus (GP) on unenhanced T1-weighted magnetic resonance (MR) images due to gadolinium retention. MATERIALS AND METHODS: A total of 189 patients who had undergone at least 2

Materials ChemistryMaterials Science
13
Article|22 citations·2012
MR imaging findings of extraventricular neurocytoma: a series of ten patients confirmed by immunohistochemistry of IDH1 gene mutation
Kyung Sik Yi, Chul‐Ho Sohn, Tae Jin Yun, Seung Hong Choi, Ji‐hoon Kim, Moon Hee Han, Chul‐Kee Park, Sung‐Hye Park, K H Chang
SJR Q1Acta Neurochirurgica
GeneticsMedicine
14
Article|17 citations·2009
Perfusion Computed Tomography Evaluation of Cerebral Hemodynamic Impairment in Patients With Unilateral Chronic Steno-Occlusive Disease
Eunhee Kim, Chul‐Ho Sohn, Dong Gyu Na, Jeong Eun Kim, K H Chang, Ji‐hoon Kim, Se Jeong Jeon
SJR Q3Journal of Computer Assisted Tomography

Mean transit time is the most predictive parameter for assessing decreased CVR in patients with unilateral steno-occlusive vascular disease.

Pulmonary and Respiratory MedicineMedicine
15
Article|16 citations·2020
<p>Prediction of Amyloid Positivity in Mild Cognitive Impairment Using Fully Automated Brain Segmentation Software</p>
Koung Mi Kang, Chul‐Ho Sohn, Min Soo Byun, Jun Ho Lee, Dahyun Yi, Younghwa Lee, Jun‐Young Lee, Yu Kyeong Kim, Bo Kyung Sohn, Roh‐Eul Yoo, Tae Jin Yun, Seung Hong Choi
SJR Q2Neuropsychiatric Disease and TreatmentOA

Relative hippocampal volume measures provided by automated brain segmentation software can be useful for screening cerebral Aβ positivity in clinical practice for patients with amnestic MCI. The information may also help clinicians interpret structural MRI to predict outcomes and determine early intervention for delaying the progression to Alzheimer's disease dementia.

Psychiatry and Mental healthMedicine

Research Areas

Radiology, Nuclear Medicine and ImagingPsychiatry and Mental healthGeneticsNeurologyEpidemiologyPulmonary and Respiratory Medicine

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