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Chung-hyuk Choi

Hanyang University · 医学

研究室紹介

Professor Chung-hyuk Choi's research lab specializes in orthopedic biomechanics and joint preservation, with a strong focus on total knee arthroplasty (TKA) in challenging patient populations, including younger patients and those with rheumatoid arthritis. The lab investigates innovative implant techniques—such as metal block augmentation for tibial bone defects—and explores biological modulation of osteoarthritis through herbal compounds that inhibit cartilage degradation. Additionally, the lab conducts clinical studies on venous thromboembolism prophylaxis in Asian patients following TKA, emphasizing patient-specific outcomes and safety.

total knee arthroplastytibial bone defectsosteoarthritisvenous thromboembolismcartilage protection

Research Overview

Papers
124
Total Citations
1,056
Papers (5y)
8
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
8total
2021
2022
2023
2025
2026
Citations per year (5y)
140total
20212022202320252026

Selected Papers

15
1
Article|89 citations·2012
Total Knee Arthroplasty in Rheumatoid Arthritis
Jin Kyu Lee, Choong-Hyeok Choi
SJR Q1Knee Surgery and Related ResearchOA

techniques must be taken into account, in order to improve the results of TKA in this subgroup of patients. Preoperative Considerations Age and ActivityRA patients are often younger (by approximately 10 or more years) than osteoarthritis (OA) patients at the time of TKA.The life span of RA patients with a knee replacement is not well known, however, assuming that RA patients have a normal life span, a TKA in this subgroup of patients on average needs to last longer and accordingly, the potential

RheumatologyMedicine
2
Article|72 citations·2014
The Effect of a Single Dose of Preemptive Pregabalin Administered With COX-2 Inhibitor: A Trial in Total Knee Arthroplasty
Jin Kyu Lee, Kyu Sung Chung, Choong Hyeok Choi
SJR Q1The Journal of Arthroplasty
SurgeryMedicine
3
Article|68 citations·2015
Risk factors of delirium in patients undergoing total knee arthroplasty
Kyu Sung Chung, Jin Kyu Lee, Jin-Sik Park, Choong Hyeok Choi
SJR Q1Archives of Gerontology and Geriatrics
Critical Care and Intensive Care MedicineMedicine
4
5
Article|32 citations·2014
Posttraumatic Stress Disorder Associated With Orthopaedic Trauma
Chang‐Hoon Lee, Choong Hyeok Choi, Sang-Young Yoon, Jin Kyu Lee
SJR Q1Journal of Orthopaedic Trauma

Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.

Clinical PsychologyPsychology
6
Article|23 citations·2012
Two-stage Reimplantation in Infected Total Knee Arthroplasty Using a Re-sterilized Tibial Polyethylene Insert and Femoral Component
Jin Kyu Lee, Choong Hyeok Choi
SJR Q1The Journal of Arthroplasty
SurgeryMedicine
7
Article|18 citations·2012
Revision Total Knee Arthroplasty Using a Constrained Condylar Knee Prosthesis in Conjunction with A Posterior Stabilized Articular Polyethylene
Jin Kyu Lee, Sung‐Jae Kim, Choong Hyeok Choi, Hyun-Kee Chung
SJR Q1The Journal of Arthroplasty
SurgeryMedicine
8
Article|18 citations·2014
SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes
Choong Hyeok Choi, Tae‐Hwan Kim, Yoon‐Kyoung Sung, Chan‐Bum Choi, Young-In Na, Hunseung Yoo, Jae‐Bum Jun
SJR Q2The Korean Journal of Internal MedicineOA

SKI306X and its herbal components inhibit GAG degradation and catabolic gene expression in human OA chondrocytes and cartilage explants. SKI306X likely also contains one or more ADAMTS-4 inhibitor.

RheumatologyMedicine
9
Article|16 citations·2020
The Impact of Epinephrine in the Periarticular Injection Cocktail using Ropivacaine for Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind Comparison Study
Dong Yi Kong, Jeong Han Oh, Won Rak Choi, Young-Il Ko, Choong Hyeok Choi
SJR Q1The Journal of Arthroplasty
SurgeryMedicine
10
Article|13 citations·2013
Management of Tibial Bony Defect with Metal Block in Primary Total Knee Replacement Arthroplasty
Seung‐Wook Baek, Chul-Woong Kim, Choong Hyeok Choi
SJR Q1Knee Surgery and Related ResearchOA

PURPOSE: To analyze minimum 2-year clinical and radiological follow-up results of primary total knee replacement arthroplasty (TKRA) with metal block augmentation for tibial bony defect. MATERIALS AND METHODS: We analyzed 67 cases (52 patients) of primary TKRA with metal block augmentation for tibial bony defects from March 1999 and March 2008. Clinical results were evaluated using the Knee Society clinical rating system and the Western Ontario and McMaster University (WOMAC) score. Radiologic r

SurgeryMedicine
11
Article|13 citations·2016
Should the position of the patellar component replicate the vertical median ridge of the native patella?
Rae Hyeong Lee, Hae Won Jeong, Jin Kyu Lee, Choong Hyeok Choi
SJR Q2The Knee
Biomedical EngineeringEngineering
12
Article|12 citations·2014
Double metal tibial blocks augmentation in total knee arthroplasty
Kyu Sung Chung, Jin Kyu Lee, Hee Jae Lee, Choong Hyeok Choi
SJR Q1Knee Surgery Sports Traumatology Arthroscopy

PURPOSE: Severe uncontained tibial bone defects occurring during total knee arthroplasty are challenging, and which treatment method is the best remains unknown. In this study, clinical and radiographic outcomes of double metal blocks augmentation were examined. METHODS: Between 2004 and 2012, double metal blocks augmentation was carried out in 17 patients with severe asymmetric uncontained tibial bone defects. The first block was attached to the tibial tray with screws, and then the second bloc

SurgeryMedicine
13
Article|8 citations·2018
Rivaroxaban and Acetylsalicylic Acid for Prevention of Venous Thromboembolism Following Total Knee Arthroplasty in Korean Patients
Kyu Sung Chung, Tae Yang Shin, Sang Hoon Park, Hyuck Kim, Choong Hyeok Choi
SJR Q1Knee Surgery and Related ResearchOA

PURPOSE: To investigate the incidence of venous thromboembolism (VTE) after total knee arthroplasty (TKA) with chemoprophylaxis using acetylsalicylic acid (AA) or rivaroxaban in Korean patients. MATERIALS AND METHODS: Between May 2011 and November 2013, 268 TKA patients (330 cases) were randomly allocated to 3 groups (group A: subcutaneous injection of 5,000 IU low-molecular-weight heparin for 2 days followed by oral administration of 100 mg AA for 5 days; group X7: oral administration of 10mg r

Internal MedicineMedicine
14
Article|7 citations·2023
The additional tibial stem extension is not mandatory for the stability of 5 mm metal block augmented tibial prosthesis construct in primary total knee arthroplasty: 5-year minimum follow-up results
Jae Joon Ryu, Yeong Hwan Kim, Choong-Hyeok Choi
SJR Q1Knee Surgery and Related ResearchOA

PURPOSE: To determine whether additional stem extension for stability is necessary, we performed mid-term follow-up of patients who had been managed with 5-mm metal block augmentation for a tibial defect, where tibial prosthesis was fixed using bone cement without stem extension. Also, we evaluated clinical and radiologic results including survival rate of patients without stem extension. METHODS: We retrospectively analyzed patients with tibial bone defect, had undergone primary total knee arth

SurgeryMedicine
15
Article|4 citations·2001
Measurement of Posterior Slope Angle of the Proximal Tibia by MRI and X-ray
Choong Hyeok Choi, Jong H. Kim, Hyun Kee Chung, Yong Hyun Choi
The Journal of the Korean Orthopaedic Association
EpidemiologyMedicine

Research Areas

SurgeryRheumatologyOrthopedics and Sports MedicineBiomedical EngineeringEpidemiologyPharmacology

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