Dae Jung Kim
Yonsei University · 医学
研究室紹介
Professor Dae Jung Kim's research lab focuses on metabolic and chronic disease epidemiology, with a strong emphasis on the role of nutritional factors, lifestyle behaviors, and biomarkers in the development of type 2 diabetes, non-alcoholic fatty liver disease (NAFLD), and cardiovascular outcomes. The lab investigates long-term associations of micronutrients like magnesium, bioactive compounds such as indole-3-carbinol, and sleep duration with metabolic health and systemic inflammation. Using large-scale population-based cohorts and preclinical models, the lab aims to identify modifiable risk factors and develop predictive tools for early detection and prevention of metabolic disorders.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15OBJECTIVE: To investigate the long-term associations of magnesium intake with incidence of diabetes, systemic inflammation, and insulin resistance among young American adults. RESEARCH DESIGN AND METHODS: A total of 4,497 Americans, aged 18-30 years, who had no diabetes at baseline, were prospectively examined for incident diabetes based on quintiles of magnesium intake. We also investigated the associations between magnesium intake and inflammatory markers, i.e., high-sensitivity C-reactive pro
Diabetes is an increasing global health problem worldwide. Diabetes and its complications have become a major cause of morbidity and mortality in Korea. The prevalence of diabetes in Korea has increased six- to seven-fold from 1.5% to 9.9% in the past 40 years. The prevalence of impaired fasting glucose also increased to about 20% in 2009. The International Diabetes Federation has estimated that the prevalence of diabetes will rise to 11.4% in 2030. Possible risk factors for diabetes in Korea ar
The new non-laboratory-based self-assessment score may be useful for identifying individuals at high-risk of NAFLD. Further studies are warranted to evaluate the utility and feasibility of the scores in various settings.
The modification potential of indole-3-carbinol (I3C), a naturally occurring compound found in cruciferous vegetables, on neoplastic development was assessed using a rat medium-term multiorgan carcinogenesis model. One-hundred male Sprague-Dawley (SD) rats were randomly divided into three groups and sequentially treated with diethylnitrosamine (DEN; 100 mg/kg b.w., a single i.p.), N-methyl-N-nitrosourea (MNU; 20 mg/kg b.w., four times i.p., at days 5, 8, 11 and 14), and dihydroxy-di-N-propyl-nit
This study aimed to investigate the association between self-reported sleep duration and general and abdominal obesity in Korean adults. A total of 8,717 adults aged 20-65 years from the Korean National Health and Nutrition Examination Survey (KNHANES) 2001 and 2005 were included. General obesity was defined as BMI >or=25 kg/m(2) and abdominal obesity as waist circumference >or=90 cm in men and >or=85 cm in women. To control for sociodemographic and lifestyle factors and comorbidities, multivari
AIM: To examine the real-world cardiovascular effectiveness and safety associated with sodium-glucose co-transporter-2 (SGLT2) inhibitor compared with dipeptidyl peptidase-4 (DPP-4) inhibitor treatment in older adults with type 2 diabetes. MATERIALS AND METHODS: In this retrospective cohort study, older adults with type 2 diabetes (aged ≥65 years) were identified in the Korean National Health Insurance Service database from September 2014 to December 2016. In total, 408 506 new users of an SGLT2
This study examined the feasibility of using black rice bran (BRB) as an ingredient of noodles and evaluated the effect of BRB incorporation in noodles in terms of chemical and functional attributes. Noodles were prepared with BRB as an ingredient at different levels (2%, 5%, 10%, and 15%). Addition of BRB (5%, 10%, and 15%) significantly decreased the cohesiveness of noodles in texture evaluation. Noodles with different levels of BRB were functionally evaluated and content of polyphenolics, fla
The silylation of SBA-15 enhances the reducibility of cobalt oxides on a SBA-15 supported cobalt catalyst, and consequently increases the catalytic activity for Fischer-Tropsch synthesis of hydrocarbons from syngas and selectivity for longer chain products.
An injection rate of 4-5 mL/sec as a saline solution chaser is optimal for achieving maximum attenuation values of the aorta or coronary arteries by using 64-section CT with 60 mL contrast material.
Abstract Background The “obesity paradox” has not been elucidated in the long-term outcomes of acute coronary syndrome (ACS). We investigated the association between obesity and cardiovascular (CV) outcomes in ACS patients with and without diabetes. Methods We identified 6978 patients with ACS aged 40–79 years from the Korean National Health Insurance Service-Health Screening Cohort between 2002 and 2015. Baseline body mass index (BMI) was categorized as underweight (< 18.5 kg/m 2 ), normal w