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Dae-Yong Kim

Seoul National University · 医学

研究室紹介

Professor Dae-Yong Kim's research lab specializes in translational oncology and gastrointestinal cancer therapeutics, with a focus on molecular mechanisms underlying carcinogenesis and treatment response in colorectal and gastric cancers. The lab investigates epigenetic regulators such as histone deacetylases (HDACs), evaluates the impact of preoperative therapies like chemoradiotherapy on surgical outcomes, and explores novel radiation and natural compound-based treatments for hepatocellular carcinoma and portal vein thrombosis. The research integrates molecular biology, clinical pathology, and surgical oncology to improve patient prognosis and treatment strategies.

colorectal cancergastric cancerepigeneticsradiation therapynatural compounds

Research Overview

Papers
230
Total Citations
1,153
Papers (5y)
31
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
31total
2022
2023
2024
2025
2026
Citations per year (5y)
114total
20222023202420252026

Selected Papers

15
1
Article|28 citations·2007
Retrospective study of canine cutaneous tumors in Korea
김대용, Bidur Pakhrin, Min-Soo Kang, 배일홍, 박미선, Hyang Jee, 유미현, 김재훈, 윤병일, 최양규

Over the 42 month period from January 2003 to June 2006, a total of 2,952 canine biopsy specimens were received from the Veterinary Medical Teaching Hospital of Seoul National University and from veterinary practitioners across the nation. Out of these, 748 (25.34%) cases were diagnosed as canine cutaneous tumors in the Department of Veterinary Pathology, College of Veterinary Medicine, Seoul National University, Korea. Thirty-eight different types of cutaneous tumors were identified and categor

2
Review|28 citations·2009
Intradural Spinal Metastasis to the Cauda Equina in Renal Cell Carcinoma
Dae-Yong Kim, Jung-Kil Lee, Sung-Jun Moon, Seok-Cheol Kim, Cheol-Su Kim
SJR Q1Spine

Although the majority of cauda equina tumors are primary tumors, intradural metastasis should be considered before surgery in patients with previously treated RCC.

SurgeryMedicine
3
Review|19 citations·2023
Common Regulators of Lipid Metabolism and Bone Marrow Adiposity in Postmenopausal Women
Dae-Yong Kim, Seong‐Hee Ko
SJR Q1PharmaceuticalsOA

A variety of metabolic disorders are associated with a decrease in estradiol (E2) during natural or surgical menopause. Postmenopausal women are prone to excessive fat accumulation in skeletal muscle and adipose tissue due to the loss of E2 via abnormalities in lipid metabolism and serum lipid levels. In skeletal muscle and adipose tissue, genes related to energy metabolism and fatty acid oxidation, such as those encoding peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) and e

Orthopedics and Sports MedicineMedicine
4
Article|18 citations·1999
Telomerase RNA expression during progression of gastric cancer
Asha Rathi, Kwon Hur, Adi F. Gazdar, Ji-Seon Bae, Ja–June Jang, Dae-Yong Kim
SJR Q1Human Pathology
PhysiologyMedicine
5
Article|11 citations·1994
Paraganglioma in the Vertebral Canal of a Cow
Dae-Yong Kim, E. Clay Hodgin, Mae K. Lopez, Alvin C. Camus, D. Gene Luther
SJR Q2Journal of Veterinary Diagnostic InvestigationOA

Paragangliomas are neoplastic proliferations of extra-adrenal paraganglionic cells and belong to the neuroendocrine tumor family. Paraganglion cells embryologically arise from the neural crest ectoderm and are distributed segmentally and symmetrically along the longitudinal axis of the body as minute aggregates. 4 Based on the anatomical distribution, innervation, and microscopic structure, the paraganglion system is divided into 2 main groups: the adrenal medulla and the extra-adrenal paragangl

SurgeryMedicine
6
Article|8 citations·2011
Nasopharyngeal Oncocytoma in a Cat
Mi‐Hyeon You, Yong-Baek Kim, Gye‐Hyeong Woo, Jun‐Young Kim, Junghee Yoon, Hwa‐Young Youn, Dae-Yong Kim
SJR Q2Journal of Veterinary Diagnostic Investigation

A 5-year-old male neutered Siamese cat was referred because of nasal swelling, nasal discharge, and oral respiration. Computed tomography and necropsy following euthanasia revealed a firm tan mass in the nasopharynx, occluding the nasal passage. Histologically, the nasopharyngeal mass was composed of solid nests, anastomosing cords, and closely packed glands separated by a delicate fibrovascular stroma. Individual neoplastic cells were cylindrical to polyhedral in shape, had distinct cell border

Pulmonary and Respiratory MedicineMedicine
7
Article|6 citations·2023
Latent Class Analysis on Types of Challenging Behavior in Persons with Developmental Disabilities: Focusing on Factors Affecting the Types of Challenging Behavior
Dae-Yong Kim
SJR Q1Behavioral SciencesOA

This study sought to analyze the latent classes of challenging behaviors among persons with developmental disabilities and examine the effects of related variables. To this end, the Korea Employment Agency for Persons with Disabilities collected data from the Survey on the Work and Life of Persons with Developmental Disabilities from 3000 households that included at least one family member with a developmental disability aged ≥15 years, surveying the persons themselves as well as their caregiver

Public Health, Environmental and Occupational HealthMedicine
8
Article|5 citations·2009
Pleomorphic Leiomyosarcoma in the Hind Leg of a Taiwanese Macaque ( Macaca Cyclopis )
Yongbaek Kim, Hyungjin Kim, Doo‐Youn Cho, Minsoo Kang, Mi-Jin You, Dae-Yong Kim
SJR Q2Journal of Veterinary Diagnostic Investigation

An adult, captive Taiwanese monkey (Macaca cyclopis) presented clinically with a large, rapidly growing mass located in the crus of the left hind leg. The overlying skin was severely ulcerated and necrotic. Radiographs suggested an invasive neoplasm in soft tissue with no bone involvement. The animal's clinical condition progressively worsened over the next 3 months until it died. Necropsy revealed that the mass infiltrated the surrounding skeletal muscle with no evidence of distant metastasis.

Pulmonary and Respiratory MedicineMedicine
9
Article|5 citations·2015
SQUAMOUS CELL CARCINOMA IN A NINE-BANDED ARMADILLO (DASYPUS NOVEMCINCTUS)
Bo-ram Lee, Sukhun Oh, Su-hyung Lee, Yongahn Kim, Soong-Hee Youn, Yangbeom Kim, Soowhan Kwon, Dae-Yong Kim
SJR Q2Journal of Zoo and Wildlife Medicine

Squamous cell carcinomas (SCCs) are tumors that occur in most animals and show strong invasiveness into surrounding tissues and nearby osseous tissues. This report describes a case of SCC in a 5-yr-old female nine-banded armadillo (Dasypus novemcinctus) with a hemorrhagic mass on the left mandibular region. The tumor originated in skin tissues and showed invasion of the oral cavity, adjacent to the submandibular salivary gland histologically. To our knowledge, this is the first report of a SCC i

Pulmonary and Respiratory MedicineMedicine
10
Article|5 citations·2006
Multilobular tumor of the mandible in a Pekingese dog
김대용, 배일홍, Hyang Jee, Min-Soo Kang, Bidur Pakhrin

Multilobular tumor of bone detected in a 2.5-year-old male Pekingese dog is reported. Grossly, the neoplasm consisted of multiple, variably sized, gritty, grayish-white to yellow nodules separated by thick collagenous septa. Histologically, these nodules contained multiple lobules of irregularly shaped and sized islands of well-differentiated osteoid and cartilage, separated by anastomosing fibrovascular septa. Chondrocytes and osteocytes were observed in the lacunae and in more osseous islands

11
Article|4 citations·2025
Genetic and biological characterization of African swine fever virus clones selected at the early stages of adaptation in Vero cells
Tae-Young Suh, Ji Hoon Park, Chae-Rin Park, Ji-Eun Kim, Jun Young Park, Seong Yun Hwang, Yong‐Joo Kim, Hae‐Eun Kang, Dae-Yong Kim, Jun‐Gu Choi
SJR Q2Archives of Virology
Agronomy and Crop ScienceAgricultural and Biological Sciences
12
Article|3 citations·2025
Prevalence of pathogens in abnormal honey bees in South Korea, 2020–2023
Juhaeng Heo, Dae‐Sung Yoo, Doo‐Sung Cheon, Yongrae Kim, Dae-Yong Kim
SJR Q2Journal of Veterinary Diagnostic InvestigationOA

South Korea’s beekeeping industry has been facing a major crisis due to colony collapse disorder (CCD), manifesting since the winter of 2021. CCD in South Korea is presumed to be caused by a combination of factors, including an abnormal climate, pesticide use, declining source plants, and increased honey bee diseases. We examined the prevalence of 12 major honey bee ( Apis mellifera) pathogens by sampling 3,707 colonies with abnormal behavior and suspected pathogen infections from 1,378 apiaries

Insect ScienceAgricultural and Biological Sciences
13
Article|3 citations·2007
Hepatocellular adenoma in a Eurasian otter (Lutra lutra)
김대용, 배일홍, Bidur Pakhrin, Hyang Jee, 신남식

A 7-year-old female Eurasian otter (Lutra lutra) at the Seoul Grand Park, Korea, died after displaying depression, anorexia, weight loss and rough skin for several days. At necropsy, a solitary friable round mass, which was approximately 12 × 9 × 5 cm and mottled dark red and yellow, was found bulging from the right hepatic lobe. Microscopically, the nonencapsulated, poorly circumscribed mass was composed of solid sheets of neoplastic hepatocytes. In addition, numerous small tan foci, ranging fr

14
Article|2 citations·2024
Direct Repair of Symptomatic Lumbar Spondylolysis Using Rod-Screw-Cable System
Dae-Yong Kim, Sang-Ryul Jin, Sung-Min Hur, Ji-Hun Chung, Seung Myung Lee, Pius Kim
SJR Q2World Neurosurgery
Pathology and Forensic MedicineMedicine
15
Article|2 citations·2003
Neospora응집반응을 이용한 네오스포라증의 혈청학적 진단
김대용, 강민수, 김재훈, 황우석, 남호우, 윤희정, 배종희

Currently, both the indirect fluorescent antibody test (IFAT) and enzyme linked immunosorbent assay (ELISA) have been used to detect Neospora caninum antibodies. Several factors such as the buffers, the conjugate, the pattern of fluorescence, and the cross reactivity with other apicomplexan protozoan, may result in poorly correlated data. The present study was undertaken to develop and evaluate the Neospora agglutination test (NAT) for the detection and quantification of IgG antibodies to N. can

Research Areas

Pulmonary and Respiratory MedicineEpidemiologySurgeryMolecular BiologyPathology and Forensic MedicineOncology

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