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Daesoo Kim

Korea Advanced Institute of Science and Technology · 神経科学

研究室紹介

Professor Daesoo Kim's research lab specializes in neuroengineering and translational neuroscience, focusing on the development of implantable bioelectronic devices for neuromodulation and the investigation of ion channels and metabolic pathways in neurological disorders. The lab integrates flexible electronics, such as piezoelectric energy harvesters and microelectrode arrays (e.g., iWEBS), to enable long-term, stable brain-computer interfaces in freely moving animals. Research also spans molecular mechanisms of pain modulation, particularly T-type calcium channels in thalamic processing, and the role of metabolic regulators like NQO1 in aging and neurodegeneration. Additionally, the lab explores the neurobiological basis of movement disorders, including dystonia, through serotonin receptor modulation.

neural interfacesT-type calcium channelsNQO1flexible electronicsdeep brain stimulation

Research Overview

Papers
208
Total Citations
9,369
Papers (5y)
46
Primary Field
神経科学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
46total
2021
2022
2023
2024
2025
Citations per year (5y)
287total
20212022202320242025

Selected Papers

15
1
Article|773 citations·2014
GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease
Seonmi Jo, Oleg Yarishkin, Yu Jin Hwang, Ye Eun Chun, Mijeong Park, Dong Ho Woo, Jin Young Bae, Tae-Keun Kim, Jaekwang Lee, Heejung Chun, Hyun-Jung Park, Da Yong Lee
SJR Q1Nature MedicineOA
NeurologyNeuroscience
2
Article|524 citations·2015
Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy
Jae Seok Lim, Woo-Il Kim, Hoon‐Chul Kang, Se Hoon Kim, Ah Hyung Park, Eun-Kyung Park, Young‐Wook Cho, Sangwoo Kim, Ho Min Kim, Jeong A. Kim, Junho Kim, Hwanseok Rhee
SJR Q1Nature MedicineOA
Molecular BiologyBiochemistry, Genetics and Molecular Biology
3
Article|521 citations·2001
Lack of the Burst Firing of Thalamocortical Relay Neurons and Resistance to Absence Seizures in Mice Lacking α1G T-Type Ca2+ Channels
Daesoo Kim, Inseon Song, Sehoon Keum, Taehoon Lee, Myung-Jin Jeong, Sung-Sook Kim, Maureen W. McEnery, Hee‐Sup Shin
SJR Q1NeuronOA
Cellular and Molecular NeuroscienceNeuroscience
4
Article|307 citations·1997
Phospholipase C isozymes selectively couple to specific neurotransmitter receptors
Daesoo Kim, Ki Sun Jun, Seong‐Beom Lee, Nae Gyu Kang, Do Sik Min, Young‐Hoon Kim, Sung Ho Ryu, Pann‐Ghill Suh, Hee‐Sup Shin
SJR Q1Nature
Cellular and Molecular NeuroscienceNeuroscience
5
Article|250 citations·2015
Self-powered deep brain stimulation via a flexible PIMNT energy harvester
Geon-Tae Hwang, Youngsoo Kim, Jeong‐Ho Lee, SeKwon Oh, Chang Kyu Jeong, Dae Yong Park, Jungho Ryu, HyukSang Kwon, Sang-Goo Lee, Boyoung Joung, Daesoo Kim, Keon Jae Lee
SJR Q1Energy & Environmental Science

A self-powered deep brain stimulation has been demonstrated by a flexible piezoelectric PIMNT energy harvester to induce behavioural changes in a mouse.

Cellular and Molecular NeuroscienceNeuroscience
6
Article|225 citations·2003
Thalamic Control of Visceral Nociception Mediated by T-Type Ca 2+ Channels
Daesoo Kim, Donghyun Park, Soonwook Choi, Sukchan Lee, Minjeong Sun, Chanki Kim, Hee‐Sup Shin
SJR Q1Science

Sensations from viscera, like fullness, easily become painful if the stimulus persists. Mice lacking alpha1G T-type Ca2+ channels show hyperalgesia to visceral pain. Thalamic infusion of a T-type blocker induced similar hyperalgesia in wild-type mice. In response to visceral pain, the ventroposterolateral thalamic neurons evokeda surge of single spikes, which then slowly decayed as T type-dependent burst spikes gradually increased. In alpha1G-deficient neurons, the single-spike response persiste

PhysiologyMedicine
7
Article|197 citations·2015
Strategic agility of Korean small and medium enterprises and its influence on operational and firm performance
Hojung Shin, Jae-Nam Lee, Daesoo Kim, Hosun Rhim
SJR Q1International Journal of Production Economics
Management of Technology and InnovationBusiness, Management and Accounting
8
Article|164 citations·2015
Optogenetic control of endogenous Ca2+ channels in vivo
Taeyoon Kyung, Sangkyu Lee, Jung Eun Kim, Taesup Cho, Hyerim Park, Yun‐Mi Jeong, Dongkyu Kim, Anna Shin, Sungsoo Kim, Jinhee Baek, Ji-Hoon Kim, Na Yeon Kim
SJR Q1Nature Biotechnology
Cellular and Molecular NeuroscienceNeuroscience
9
Article|163 citations·2009
Economic production quantity model with imperfect-quality items, two-way imperfect inspection and sales return
Seung Ho Yoo, Daesoo Kim, Myung-Sub Park
SJR Q1International Journal of Production Economics
Management Information SystemsBusiness, Management and Accounting
10
Article|130 citations·2017
Inhibitory Basal Ganglia Inputs Induce Excitatory Motor Signals in the Thalamus
Jeong-Jin Kim, Youngsoo Kim, Ryuichi Nakajima, Anna Shin, Minju Jeong, Ah Hyung Park, Yong‐Cheol Jeong, Seonmi Jo, Seungkyoung Yang, Hosung Park, Sung‐Hwan Cho, Kwang‐Hyun Cho
SJR Q1NeuronOA
NeurologyMedicine
11
Article|125 citations·1998
Optimal joint pricing and lot sizing with fixed and variable capacity
Daesoo Kim, Won Jin Lee
SJR Q1European Journal of Operational Research
Management Information SystemsBusiness, Management and Accounting
12
Article|91 citations·2017
Optogenetic control of body movements via flexible vertical light-emitting diodes on brain surface
Seunghyun Lee, Jeong-Jin Kim, Jung H. Shin, Han Eol Lee, Il‐Suk Kang, Kiuk Gwak, Dae‐Shik Kim, Dae-Shik Kim, Daesoo Kim, Daesoo Kim, Keon Jae Lee
SJR Q1Nano Energy
Cellular and Molecular NeuroscienceNeuroscience
13
Article|87 citations·2020
Optogenetic brain neuromodulation by stray magnetic field via flash-enhanced magneto-mechano-triboelectric nanogenerator
Han Eol Lee, Jung Hwan Park, Dahee Jang, Jung H. Shin, Tae Hong Im, Jae Hee Lee, Seong Kwang Hong, Hee Seung Wang, Min Sub Kwak, Mahesh Peddigari, Chang Kyu Jeong, Yuho Min
SJR Q1Nano Energy
Biomedical EngineeringEngineering
14
Article|87 citations·2014
Pricing and return policy under various supply contracts in a closed-loop supply chain
Seung Ho Yoo, Daesoo Kim, Myung-Sub Park
SJR Q1International Journal of Production Research

This study investigates pricing and return policies under various supply contracts in a closed-loop supply chain in which a supplier has more bargaining power than a retailer. We develop integrated supply contract models based on the principal–agent paradigm. Specifically, the supplier with more bargaining power devises a supply contract, acting as a Stackelberg leader. Then, given the contract offer, the retailer decides on pricing and return policies which affect consumers’ demand and return b

Management Information SystemsBusiness, Management and Accounting
15
Article|61 citations·2016
Optogenetic Mapping of Functional Connectivity in Freely Moving Mice via Insertable Wrapping Electrode Array Beneath the Skull
Ah Hyung Park, Seung Hyun Lee, Changju Lee, Jeongjin Kim, Han Eol Lee, Se‐Bum Paik, Keon Jae Lee, Daesoo Kim
SJR Q1ACS Nano

Spatiotemporal mapping of neural interactions through electrocorticography (ECoG) is the key to understanding brain functions and disorders. For the entire brain cortical areas, this approach has been challenging, especially in freely moving states, owing to the need for extensive craniotomy. Here, we introduce a flexible microelectrode array system, termed iWEBS, which can be inserted through a small cranial slit and stably wrap onto the curved cortical surface. Using iWEBS, we measured dynamic

Cellular and Molecular NeuroscienceNeuroscience

Research Areas

Cellular and Molecular NeuroscienceMolecular BiologyManagement Information SystemsNeurologyCognitive NeuroscienceStrategy and Management

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