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Dong Sup Yoon

Yonsei University · 医学

研究室紹介

Professor Dong Sup Yoon's research lab specializes in surgical critical care and hepatobiliary-pancreatic surgery, with a strong focus on improving the diagnosis, severity assessment, and management of acute cholecystitis and cholangitis. The lab is at the forefront of developing and validating clinical guidelines, such as the Tokyo Guidelines (TG13 and TG18), which standardize diagnostic criteria and treatment algorithms based on evidence and big data. Their work emphasizes risk stratification using tools like the Charlson Comorbidity Index and ASA-PS, and investigates predictive factors for postoperative complications such as pancreatic fistula. The lab also explores prognostic factors in metastatic disease, particularly adrenal metastasis and lymph node involvement in gastrointestinal cancers.

acute cholecystitisTokyo Guidelinessurgical outcomespancreatic fistulalymph node metastasis

Research Overview

Papers
286
Total Citations
10,332
Papers (5y)
14
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
14total
2022
2023
2024
2025
2026
Citations per year (5y)
77total
20222023202420252026

Selected Papers

15
1
Review|1,474 citations·2017
Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos)
Masamichi Yokoe, Jiro Hata, Tadahiro Takada, Steven M. Strasberg, Horacio J. Asbun, Go Wakabayashi, Kazuto Kozaka, Itaru Endo, Daniel J. Deziel, Fumihiko Miura, Kohji Okamoto, Tsann‐Long Hwang
SJR Q1Journal of Hepato-Biliary-Pancreatic SciencesOA

Abstract The Tokyo Guidelines 2013 (TG13) for acute cholangitis and cholecystitis were globally disseminated and various clinical studies about the management of acute cholecystitis were reported by many researchers and clinicians from all over the world. The 1 st edition of the Tokyo Guidelines 2007 ( TG 07) was revised in 2013. According to that revision, the TG 13 diagnostic criteria of acute cholecystitis provided better specificity and higher diagnostic accuracy. Thorough our literature sea

Pulmonary and Respiratory MedicineMedicine
2
Article|141 citations·2009
Clinical validation and risk factors for delayed gastric emptying based on the International Study Group of Pancreatic Surgery (ISGPS) Classification
Joon Seong Park, Ho Kyoung Hwang, Jae Keun Kim, Sin Il Cho, Dong Sup Yoon, Woo Jung Lee, Sang Hoon
SJR Q1SurgeryOA
OncologyMedicine
3
Article|69 citations·2007
What is the best treatment modality for adrenal metastasis from hepatocellular carcinoma?
Joon Seong Park, Dong Sup Yoon, Kyung Sik Kim, Jin Sub Choi, Woo Jung Lee, Hoon Sang Chi, Byong Ro Kim
SJR Q1Journal of Surgical OncologyOA

PURPOSE: This study aimed to analyze the effect of each therapeutic modality to clarify the treatment strategy for adrenal metastases from hepatocellular carcinoma (HCC). METHODS: Adrenal metastasis from HCC was observed in 45 patients. Fifteen patients who were determined to have multi-organ metastasis including the adrenal glands were excluded, and the remaining 30 patients were reviewed. RESULTS: The location of adrenal metastasis was right side, left side, and both in 17, 9, and 4 patients,

SurgeryMedicine
4
Article|67 citations·2007
Factors influencing recurrence after curative resection for ampulla of vater carcinoma
Joon Seong Park, Dong Sup Yoon, Kyung Sik Kim, Jin Sub Choi, Woo Jung Lee, Hoon Sang Chi, Byong Ro Kim
SJR Q1Journal of Surgical OncologyOA

BACKGROUND: Carcinoma of the ampulla of Vater has a relatively higher resection rate, lower recurrence rate, and more favorable prognosis than other malignant tumors of the periampullary region. Because of the relative low incidence of carcinoma of the ampulla of Vater, there have been few reports on the patterns and risk factors of recurrence after curative resection. The aim of this study was to evaluate the patterns and risk factors of recurrence after curative resection of ampulla of Vater c

OncologyMedicine
5
Article|45 citations·2012
The Effect of Visceral Fat Mass on Pancreatic Fistula after Pancreaticoduodenectomy
Chang Min Park, Joon Seong Park, Eun Suk Cho, Jae Keun Kim, Jeong‐Sik Yu, Dong Sup Yoon
SJR Q2Journal of Investigative SurgeryOA

VFA is a better indicator for the development of pancreatic fistula after PD than BMI. High VFA (≥100 cm(2)) is a risk factor for developing a pancreatic fistula after PD.

OncologyMedicine
6
Article|37 citations·2007
Actual Recurrence Patterns and Risk Factors Influencing Recurrence After Curative Resection with Stage II Gallbladder Carcinoma
Joon Seong Park, Dong Sup Yoon, Kyung Sik Kim, Jin Sub Choi, Woo Jung Lee, Hoon Sang Chi, Byong Ro Kim
SJR Q1Journal of Gastrointestinal SurgeryOA
SurgeryMedicine
7
Article|31 citations·2001
Genetic mapping and DNA sequence-based analysis of deleted regions on chromosome 16 involved in progression of bladder cancer from occult preneoplastic conditions to invasive disease
Dong Sup Yoon, Li Li, Ruo-dan Zhang, Andrzej Kram, Jae Y. Ro, Dennis A. Johnston, H. Barton Grossman, Steven E. Scherer, Bogdan Czerniak
SJR Q1Oncogene
SurgeryMedicine
8
Article|28 citations·2013
Drainage Volume After Pancreaticoduodenectomy Is a Warning Sign of Chyle Leakage That Inversely Correlates With a Diagnosis of Pancreatic Fistula
Jae Keun Kim, Joon Seong Park, Ho Kyoung Hwang, Hyun Wook Shin, Dong Sup Yoon
SJR Q1World Journal of SurgeryOA

BACKGROUND: Chyle leakage is a rare complication of pancreaticoduodenectomy (PD), and its association with pancreatic fistula has not been established. The aim of this study was to (1) evaluate the incidence, management, and risk factors of chyle leakage after PD; (2) determine if there is a relation between chyle leakage and diagnosis of pancreatic fistula; and (3) predict chyle leakage with drainage volume early. METHODS: A total of 222 patients underwent PD or pylorus-preserving PD. We used t

SurgeryMedicine
9
Article|25 citations·1999
Expression of biliary antigen and its clinical significance in hepatocellular carcinoma
Dong Sup Yoon, Joon Jeong, Young Nyun Park, Kyung Sik Kim, Sung Woo Kwon, Hoon Sang Chi, Chanil Park, Byong Ro Kim
SJR Q2Yonsei Medical JournalOA

In order to classify the hepatocellular carcinomas (HCCs) which had diverse clinicopathologic characteristics, we divided HCCs into two groups according to the expression of biliary antigen on the basis of the hypothesis that the hepatocyte and biliary epithelial cell originate from the same precursor cell, and then we investigated the clinical and pathologic characteristics in the two groups. Forty HCC cases with no preoperative treatment and at least two-year follow-up data were selected among

SurgeryMedicine
10
Article|16 citations·2008
Estrogen Receptor α, Estrogen Receptor β, and Progesterone Receptor as Possible Prognostic Factor in Radically Resected Gallbladder Carcinoma
Joon Seong Park, Woo Hee Jung, Jae Keun Kim, Ho Kyoung Hwang, Sin Il Cho, Dong Sup Yoon, Sang Hoon, Byong Ro Kim
SJR Q1Journal of Surgical ResearchOA
SurgeryMedicine
11
Article|14 citations·1998
Cell proliferation index and the expression of p53 and Bcl-2 in tumorous and non-tumorous lesions of hepatocellular carcinoma and metastatic liver cancer
Dong Sup Yoon, Jae‐Ho Cheong, Young Nyun Park, Sung Woo Kwon, Hoon Sang Chi, Byong Ro Kim
SJR Q2Yonsei Medical JournalOA

In the development of a cancer, unlimited cell proliferation has been believed to play an important role. In addition, a programmed cell death called apoptosis, which is regulated by several oncogenes and tumor suppressor genes, has been suggested to be another important different pathway of carcinogenesis. Recently, several reports on cell proliferation capacity and apoptosis in the development of human liver disease have been published, but the cell proliferation index and its relationship bet

OncologyMedicine
12
Article|12 citations·2008
Left hemihepatectomy and caudate lobectomy and complete extrahepatic bile duct resection using transduodenal approach for hilar cholangiocarcinoma arsing from Biliary Papillomatosis
Jae Keun Kim, Ho Kyoung Hwang, Joon Seong Park, Sin Il Cho, Dong Sup Yoon, Hoon Sang Chi
SJR Q1Journal of Surgical OncologyOA

BACKGROUND: Biliary papillomatosis (BP) is a rare disease characterized by multiple papillary lesions of variable distribution and extent in the intra and extrahepatic bile duct. Hepatopancreatoduodenectomy (HPD) can be indicated for the resection of diffuse intra and extrahepatic BP that extended to the distal bile duct and ampullary region. The mortality rate for HPD has recently decreased but HPD still has a high morbidity rate. In this study, we present a safe procedure for concomitant intra

SurgeryMedicine
13
Article|11 citations·2013
P16 Hypermethylation Predicts Surgical Outcome Following Curative Resection of Mid/Distal Bile Duct Cancer
Joon Seong Park, Young Nyun Park, Kang Young Lee, Jae Keun Kim, Dong Sup Yoon
SJR Q1Annals of Surgical OncologyOA
SurgeryMedicine
14
Article|8 citations·2017
Preoperative fecal elastase-1 is a useful prognostic marker following curative resection of pancreatic cancer
Jin Hong Lim, Joon Seong Park, Dong Sup Yoon
SJR Q1HPBOA
OncologyMedicine
15
Article|6 citations·2012
Difference of Regeneration Potential Between Healthy and Diseased Liver
Man Ki Ju, Gi Hong Choi, Joon Seong Park, Dong Sup Yoon, Jin Sub Choi, Myoung Soo Kim, Soon Il Kim
SJR Q3Transplantation Proceedings
SurgeryMedicine

Research Areas

OncologySurgeryPulmonary and Respiratory MedicineHepatologyMolecular BiologyCancer Research

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