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Gwang-Woo Park

Yonsei University · 物理学・天文学

研究室紹介

Professor Gwang-Woo Park's research lab specializes in radiation oncology and medical physics, focusing on improving the precision and safety of radiation therapy. Key research directions include optimizing treatment techniques such as deep inspiration breath-hold (DIBH) for left-sided breast cancer, developing advanced imaging and dosimetry methods like in-vivo dosimetry and 3D-printed boluses, and establishing preclinical models for studying stereotactic body radiotherapy (SBRT)-induced normal tissue injury. The lab also investigates biomarkers of beta-cell dysfunction to predict post-transplant diabetes mellitus, highlighting a translational approach combining clinical and experimental research.

radiation therapyimage-guided radiotherapy3D-printed bolusdosimetrySBRT radiobiology

Research Overview

Papers
70
Total Citations
591
Papers (5y)
21
Primary Field
物理学・天文学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
21total
2022
2023
2024
2025
2026
Citations per year (5y)
13total
20222023202420252026

Selected Papers

15
1
Article|162 citations·2001
??-CELL DYSFUNCTION RATHER THAN INSULIN RESISTANCE IS THE MAIN CONTRIBUTING FACTOR FOR THE DEVELOPMENT OF POSTRENAL TRANSPLANTATION DIABETES MELLITUS
J. H. Nam, Junwon Mun, Soon Il Kim, Shin‐Wook Kang, Kyu Hun Choi, Kwangwoo Park, Chul Woo Ahn, Bong Soo, Young Duk Song, Seung Kil Lim, Kyung Ran Kim, H. C. Lee
SJR Q1Transplantation

These results revealed that fasting and 2-hr plasma glucose levels, as well as the proinsulin/insulin ratio before transplantation, are both possible indicators of beta-cell dysfunction and may be predictors for the development of PTDM. Furthermore, beta-cell dysfunction, rather than insulin resistance, was proven to be the main factor for the pathogenesis of PTDM.

TransplantationMedicine
2
Article|63 citations·2013
The deep inspiration breath hold technique using Abches reduces cardiac dose in patients undergoing left-sided breast irradiation
Ha Yoon Lee, Jee Suk Chang, Ik Jae Lee, Kwangwoo Park, Yong Bae Kim, Chang‐Ok Suh, Jun Won Kim, Ki Chang Keum
SJR Q2Radiation Oncology JournalOA

PURPOSE: We explored whether the deep inspiration breath hold (DIBH) technique using Abches during left-sided breast irradiation was effective for minimizing the amount of radiation to the heart and lung compared to free breathing (FB). MATERIALS AND METHODS: Between February and July 2012, a total of 25 patients with left-sided breast cancer underwent two computed tomography scans each with the DIBH using Abches and using FB after breast-conserving surgery. The scans were retrospectively replan

Cancer ResearchBiochemistry, Genetics and Molecular Biology
3
Article|55 citations·2019
Clinical Evaluation of Commercial Atlas-Based Auto-Segmentation in the Head and Neck Region
Hyothaek Lee, Eungman Lee, Nalee Kim, Joo Ho Kim, Joo ho Kim, Kwangwoo Park, Ho Lee, Jaehee Chun, Jae-ik Shin, Jee Suk Chang, Jin Sung Kim, Jin Sung Kim
SJR Q2Frontiers in OncologyOA

While atlas segmentation (AS) has proven to be a time-saving and promising method for radiation therapy contouring, optimal methods for its use have not been well-established. Therefore, we investigated the relationship between the size of the atlas patient population and the atlas segmentation auto contouring (AC) performance. A total of 110 patients’ head planning CT images were selected. The mandible and thyroid were selected for this study. The mandibles and thyroids of the patient populatio

Biomedical EngineeringEngineering
4
Article|41 citations·2016
Clinical application of 3D-printed-step-bolus in post-total-mastectomy electron conformal therapy
Kwangwoo Park, Sung Jin Park, Mi-Jin Jeon, Jinhyun Choi, Jun Won Kim, Yoon Jin Cho, Wonseok Jang, Yo Sup Keum, Ik Jae Lee
SJR Q2OncotargetOA

The 3D-printed boluses were used during the radiation therapy of the chest wall in six patients with breast cancer after modified radical mastectomy (MRM). We measured the in-vivo skin doses while both conventional and 3D-printed boluses were placed on the chest wall and compared the mean doses delivered to the ipsilateral lung and the heart. The homogeneity and conformity of the dose distribution in the chest wall for both types of boluses were also evaluated. The uniformity index on the chest

RadiationPhysics and Astronomy
5
Article|39 citations·2014
Development of a small animal model to simulate clinical stereotactic body radiotherapy-induced central and peripheral lung injuries
Zhen-Yu Hong, Sung Ho Eun, Kwangwoo Park, Won Hoon Choi, Jung Il Lee, Eunjung Lee, Jimin Lee, Michael D. Story, Jaeho Cho
SJR Q2Journal of Radiation ResearchOA

Given the tremendous potential of stereotactic body radiotherapy (SBRT), investigations of the underlying radiobiology associated with SBRT-induced normal tissue injury are of paramount importance. This study was designed to develop an animal model that simulates centrally and peripherally located clinical SBRT-induced lung injuries. A 90-Gy irradiation dose was focally delivered to the central and peripheral areas of the left mouse lung with an image-guided small-animal irradiation system. At 1

RadiationPhysics and Astronomy
6
Article|22 citations·2020
Detailed evaluation of Mobius3D dose calculation accuracy for volumetric-modulated arc therapy
Jihun Kim, Jihun Kim, Min Cheol Han, Eungman Lee, Kwangwoo Park, Kyung Hwan Chang, Dong Wook Kim, Jin Sung Kim, Jin Sung Kim, Chae‐Seon Hong
SJR Q1Physica MedicaOA
RadiationPhysics and Astronomy
7
Article|20 citations·2017
In vivo dosimetry and acute toxicity in breast cancer patients undergoing intraoperative radiotherapy as boost
Jason Joon Bock Lee, Jinhyun Choi, Sung Gwe Ahn, Joon Jeong, Ik Jae Lee, Kwangwoo Park, Kangpyo Kim, Jun Won Kim
SJR Q2Radiation Oncology JournalOA

IORT as a boost was well-tolerated among Korean women without severe acute complication. In vivo dosimetry with OSLD can help ensure safe delivery of IORT as a boost.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
8
Article|5 citations·2016
Determination of small-field correction factors for cylindrical ionization chambers using a semiempirical method
Kwangwoo Park, Jino Bak, Sung Ho Park, Wonhoon Choi, Suk Won Park
SJR Q1Physics in Medicine and BiologyOA

A semiempirical method based on the averaging effect of the sensitive volumes of different air-filled ionization chambers (ICs) was employed to approximate the correction factors for beam quality produced from the difference in the sizes of the reference field and small fields.We measured the output factors using several cylindrical ICs and calculated the correction factors using a mathematical method similar to deconvolution; in the method, we modeled the variable and inhomogeneous energy fluen

RadiationPhysics and Astronomy
9
Article|2 citations·2023
애국심과 세계시민주의 간의 관계에 대한 그리스도교적 이해 연구: 슐라이어마허의 그리스도교 윤리학적 관점을 중심으로
박광우

본 논문은 슐라이어마허의 그리스도교 윤리학적 관점을 바탕으로 애국심과 세계시민주의 간의 관계에 대한 그리스도교적인 이해를 탐구한다. 슐라이어마허에 따르면 민족 공동체는 인류애와 연결되는 최고선이 개진되는 윤리적 과정에서 나타난 공동체이며, 애국심은 민족 공동체를 통하여 선제적으로 형성된 인류애이다. 종교는 전체에 대한 수동성과 수용을 바탕으로 모두가 각자의 개성을 상호존중하고 서로 사랑하는 진정한 세계시민주의의 이념을 드러내는데, 그리스도교는 이를 예수 그리스도를 통해 계시된 하느님의 영의 역사와 거기에 근거한 형제사랑으로 나타낸다. 슐라이어마허의 그리스도교적인 이해에 따르면 하느님의 영의 역사에 기초한 그리스도교적 형제사랑인 세계시민주의는 애국심의 이념이고, 애국심은 그러한 세계시민주의가 민족 공동체 안에서 구체적으로 형성된 것이다. 이제 그리스도인은 전체로서의 하느님의 영의 역사 가운데 모든 민족이 고유한 민족성으로 그 역사를 형성하며 자유롭고 평등하게 교류한다는 그리스도교적 문

10
Article|2 citations·2016
Mechanical quality assurance using light field for linear accelerators with camera calibration
Kwangwoo Park, Wonhoon Choi, Ki Chang Keum, Ho Lee, Jeongmin Yoon, Chang Geol Lee, Ik Jae Lee, Jaeho Cho
SJR Q1Physica MedicaOA
RadiationPhysics and Astronomy
11
Article|1 citations·2020
TomoMQA: Automated analysis program for MVCT quality assurance of helical tomotherapy
Min Cheol Han, Chae‐Seon Hong, Kyung Hwan Chang, Jihun Kim, Jihun Kim, Su Chul Han, Dong Wook Kim, Kwangwoo Park, Minjoo Kim, Han‐Back Shin, Se Hyung Lee, Jin Sung Kim
SJR Q1Journal of Applied Clinical Medical PhysicsOA

Abstract Purpose In this study, we developed a simple but useful computer program, called TomoMQA, to offer an automated quality assurance for mega‐voltage computed tomography (MVCT) images generated via helical tomotherapy. Methods TomoMQA is written in MATLAB and contains three steps for analysis: (a) open the DICOM dataset folder generated via helical tomotherapy (i.e., TomoTherapy ® and Radixact™), (b) call the baseline data for the consistency test and click the “Analysis” button (or click

Electrical and Electronic EngineeringEngineering
12
Article|1 citations·2015
Determinations of the correction factors for small fields in cylindrical ionization chambers based on measurement and numerical calculation
Kwangwoo Park, Wonhoon Choi, Sung Ho Park, Jin Hwa Choi, Suk Won Park, Jino Bak
SJR Q3Journal of the Korean Physical SocietyOA

We investigated the volume averaging effect for air-filled cylindrical ionization chambers to determine the correction factors in a small photon field for a given chamber. We measured output factors with several cylindrical ionization chambers, and by using a mathematical method similar to deconvolution, we modeled the non-constant and inhomogeneous exposure function in the cavity of the chamber. The parameters in the exposure function and the correction factors were determined by solving a syst

RadiationPhysics and Astronomy
13
Article|1 citations·2015
Influence of different boost techniques on radiation dose to the left anterior descending coronary artery
박광우, 이용하, 차지혜, 유세환, 김성현, 이종영

Purpose: The purpose of this study is to compare the dosimetry of electron beam (EB) plans and three-dimensional helical tomotherapy (3DHT) plans for the patients with left-sided breast cancer, who underwent breast conserving surgery. Materials and Methods: We selected total of 15 patients based on the location of tumor, as following subsite: subareolar, upper outer, upper inner, lower lateral, and lower medial quadrants. The clinical target volume (CTV) was defined as the area of architectural

14
Article|0 citations·2023
Development of Inclined Applicators for Flattened Beam Intraoperative Radiotherapy
JeongHeon Kim, Sohyun Ahn, Kwangwoo Park, Rena Lee, Jin Sung Kim
SJR Q2Applied SciencesOA

A 3D-printed applicator for intraoperative radiation therapy (IORT) using the INTRABEAM system has been introduced, designed to protect normal tissue, expand indications, and assess its effectiveness in various intraoperative settings. The study involved designing and creating inclined applicators at 0° and 45° angles, which were capable of producing flattened and unflattened beams and shielding non-target areas from radiation. The applicator was evaluated based on dose uniformity, percentage de

RadiationPhysics and Astronomy
15
Article|0 citations·2025
Feasibility study for dose calculation with a radiation treatment planning system using a fixed-size electron cone applicator for small electron fields
Su Chul Han, Min Cheol Han, Jihun Kim, Heerim Nam, Jin Sung Kim, Kwangwoo Park
SJR Q1PLoS ONEOA

OBJECTIVE: This study aims to evaluate the feasibility of radiation treatment planning using a commercial treatment planning system (TPS) for small fixed-size electron cone electron applicators not natively supported by the TPS. METHODS: Dosimetric characteristics, including beam profiles and output factors (OFs), were compared between a 6 MeV electron beam collimated by a small fixed-size electron cone applicator and a cerrobend cutout-based general applicator. Measurements were performed using

RadiationPhysics and Astronomy

Research Areas

RadiationRadiology, Nuclear Medicine and ImagingCancer ResearchBiomedical EngineeringNuclear and High Energy PhysicsTransplantation

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