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Ha Jeong Lee

Sungkyunkwan University · 医学

研究室紹介

Professor Ha Jeong Lee's research lab focuses on antimicrobial resistance, particularly the molecular epidemiology and fitness implications of carbapenemase-producing Enterobacteriaceae. The lab investigates plasmid-mediated resistance mechanisms, including the coexistence and evolutionary dynamics of multiple carbapenemase genes in clinical isolates. Key research directions include the impact of plasmid carriage on bacterial fitness, virulence, and biofilm formation, as well as host-pathogen interactions in multidrug-resistant pathogens. The lab also explores psychosocial factors affecting chronic disease management, particularly depression and self-care in elderly patients with diabetes.

antimicrobial resistancecarbapenemase genesplasmid fitnessbacterial virulencediabetes and depression

Research Overview

Papers
156
Total Citations
1,546
Papers (5y)
24
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
24total
2021
2022
2023
2024
2025
Citations per year (5y)
265total
20212022202320242025

Selected Papers

15
1
Article|41 citations·2020
Co-introduction of plasmids harbouring the carbapenemase genes, blaNDM-1 and blaOXA-232, increases fitness and virulence of bacterial host
Haejeong Lee, Juyoun Shin, Yeun‐Jun Chung, Myungseo Park, Kyeong Jin Kang, Jin Yang Baek, Dongwoo Shin, Doo Ryeon Chung, Kyong Ran Peck, Jae‐Hoon Song, Kwan Soo Ko
SJR Q1Journal of Biomedical ScienceOA

Abstract Background Bacterial isolates with multiple plasmids harbouring different carbapenemase genes have emerged and been identified repeatedly, despite a general notion that plasmids confer fitness cost in bacterial host. In this study, we investigated the effects of plasmids with carbapenemase genes on the fitness and virulence of bacteria. Methods Different plasmids harbouring the carbapenemase genes, bla NDM-1 and bla OXA-232 , were isolated from a carbapenem-resistant K. pneumoniae strai

Molecular MedicineBiochemistry, Genetics and Molecular Biology
2
Article|27 citations·2016
The association of weather on pediatric emergency department visits in Changwon, Korea (2005–2014)
Hae Jeong Lee, Mi Hyeon Jin, Jun Hwa Lee
SJR Q1The Science of The Total Environment
Health, Toxicology and MutagenesisEnvironmental Science
3
Article|24 citations·2003
The Role of Social Support in the Relationship between Stress and Depression among Family Caregivers of Older Adults with Dementia
Hae Jung Lee, Ji Min Seo, Sukhee Ahn
Daehan ganho haghoeji

PURPOSE: This study was to determine the mediator or moderator role of social support in the relationship between stress and depression among family caregivers of older adults with dementia. METHOD: Sixty nine family caregivers were randomly selected from health care centers in P city and a face-to-face interview was conducted using questionnaires from January to May of 2002. Data were analyzed with descriptive statistics, Pearson correlation, and hierarchical multiple regression using SPSS prog

General Health ProfessionsHealth Professions
4
Article|22 citations·2018
Comparison of virulence between matt and mucoid colonies of Klebsiella pneumoniae coproducing NDM-1 and OXA-232 isolated from a single patient
Haejeong Lee, Jin Yang Baek, So Yeon Kim, Hyunji Jo, KyeongJin Kang, Jae‐Hoon Ko, Sun Young Cho, Doo Ryeon Chung, Kyong Ran Peck, Jae‐Hoon Song, Kwan Soo Ko
SJR Q2The Journal of Microbiology

Nine Klebsiella pneumoniae isolates coproducing NDM-1 and OXA-232 carbapenemases were successively isolated from a single patient. Although they were isolated simultaneously and were isogenic, they presented different colony phenotypes (matt and mucoid). All nine isolates were resistant to most antibiotics except colistin and fosfomycin. In addition, matt-type isolates were resistant to tigecycline. No differences were detected in the cps cluster sequences, except for the insertion of IS5 in the

Molecular MedicineBiochemistry, Genetics and Molecular Biology
5
Article|18 citations·2005
Self Care Activity, Metabolic Control, and Cardiovascular Risk Factors in accordance with the Levels of Depression of Clients with Type 2 Diabetes Mellitus
Hae Jung Lee, Kyung Yeon Park, Hyeong Sook Park
Daehan ganho haghoeji

PURPOSE: The purpose of this study was to explore the levels of depression experienced by clients (N=152) with Type 2 Diabetes Mellitus(DM), and to compare the levels of self care activity, metabolic control and cardiovascular risk factors between depressed and non-depressed clients. METHOD: Participants aged 50 and above were conveniently recruited in B city. The levels of depression, self-care activity, metabolic control of glucose and lipids, and cardiovascular risk factors of the participant

Endocrinology, Diabetes and MetabolismMedicine
6
Article|17 citations·2001
Predictors of Job Performance, Work Satisfaction, and Productivity among Korean Hospital Nurses
Hae Jung Lee
Daehan ganho haghoeji
Leadership and ManagementNursing
7
Article|15 citations·2005
The Effects of Problem Solving Nursing Counseling and Intensified Walking Exercise on Diabetic Self-care, Coping Strategies, and Glycemic Control among Clients with DM Type II
Hae Jung Lee, Kyung Yeon Park, Hyeong Sook Park, In Joo Kim
Daehan ganho haghoeji

PURPOSE: The purpose of the study was to identify the effects of problem solving nursing counseling and intensified walking exercise on diabetic self-care, coping strategies, and glycemic control among older adults with DM type II. METHOD: Ninety nine DM patients who were older than 50 were recruited from DM clinics or public health centers and conveniently assigned into three groups: the Polar (n=41), counseling (n=30) and control groups (n=28). Participants in both Polar and counseling groups

Speech and HearingHealth Professions
8
Article|15 citations·2021
Effect of multiple, compatible plasmids on the fitness of the bacterial host by inducing transcriptional changes
Haejeong Lee, Kwan Soo Ko
SJR Q1Journal of Antimicrobial ChemotherapyOA

OBJECTIVES: Bacteria that acquire plasmids incur a biological cost. Despite this fact, clinical Enterobacteriaceae isolates commonly contain multiple co-existing plasmids harbouring carbapenemase genes. METHODS: Six different plasmids carrying blaNDM-1, blaNDM-5, blaCTX-M-15, blaKPC-2, blaOXA-181 and blaOXA-232 genes were obtained from Klebsiella pneumoniae and Escherichia coli clinical isolates. Using the E. coli DH5α strain as recipient, 14 transconjugants with diverse plasmid combinations (si

Molecular MedicineBiochemistry, Genetics and Molecular Biology
9
Article|13 citations·2000
A New, Low-Thermal-Budget Planarization Scheme for Pre-Metal Dielectric Using Electron-Beam Cured Hydrogen Silsesquioxane in Device
Hae Jeong Lee, Juseon Goo, Seongho Kim, Jin-Gi Hong, Hyeon-Deok Lee, Ho-Kyu Kang, Sang-In Lee, Moon Yong Lee
SJR Q3Japanese Journal of Applied Physics

Employing an electron-beam (E-beam) cured hydrogen silsesquioxane (HSQ) based inorganic spin-on-glass as a pre-metal dielectric (PMD) material, we developed a simple planarization process with low thermal budget and good planarity in stacked capacitor dynamic random access memory (STC DRAM) device. We observe the basic E-beam cured HSQ film characteristics such as Fourier-transform infrared absorption spectra (FTIR), wet etch rate, film shrinkage, refractive index (RI), X-ray photoelectron spect

Electrical and Electronic EngineeringEngineering
10
Article|13 citations·2019
Evolution of Klebsiella pneumoniae with mucoid and non-mucoid type colonies within a single patient
Haejeong Lee, Juyoun Shin, Yeun‐Jun Chung, Jin Yang Baek, Doo Ryeon Chung, Kyong Ran Peck, Jae‐Hoon Song, Kwan Soo Ko
SJR Q1International Journal of Medical Microbiology
Molecular MedicineBiochemistry, Genetics and Molecular Biology
11
Article|13 citations·2019
Emotional State According to Breakfast Consumption in 62276 South Korean Adolescents
Hae Jeong Lee, Cheol Hong Kim, I Joon Han, Sung Hoon Kim
SJR Q3Iranian Journal of PediatricsOA

Objectives: Adolescents frequently skip breakfast for a variety of reasons. We investigated associations between lifestyle, emotional state, and breakfast consumption in adolescents. Methods: Data from 62276 adolescents were derived from the 13th Korean Youth Risk Behavior Web-based Survey (KYRBS), conducting from June 1, 2017 to June 30. The adolescents were drawn by stratified multistage clustered samples from 400 middle schools and 400 high schools. Breakfast skipper was defined as those who

Nutrition and DieteticsNursing
12
Article|12 citations·2011
Delayed Response of Amylin Levels after an Oral Glucose Challenge in Children with Prader-Willi Syndrome
Hae Jeong Lee, Yon Ho Choe, Jee Hyun Lee, Young Bae Sohn, Su Jin Kim, Sung Won Park, Jun Seok Son, Seon Woo Kim, Dong‐Kyu Jin
SJR Q2Yonsei Medical JournalOA

The relatively low levels of amylin, compared to those in overweight controls, during the early phase of glucose loading in patients with PWS, may contribute, in part, to the excessive appetite of PWS patients as compared to the overweight controls.

GeneticsBiochemistry, Genetics and Molecular Biology
13
Article|12 citations·2010
A Single Center Experience of Self-Bougienage on Stricture Recurrence after Surgery for Corrosive Esophageal Strictures in Children
Hae Jeong Lee, Jee Hyun Lee, Jeong Meen Seo, Suk Koo Lee, Yon Ho Choe
SJR Q2Yonsei Medical JournalOA

Although a small number of patients were studied, self-bougienage was safe, less invasive, and effective for the management of esophageal restenosis in patients who required frequent dilation after surgery.

SurgeryMedicine
14
Article|11 citations·2017
The Association between Socioeconomic Status and Obesity in Korean Children: An Analysis of the Fifth Korea National Health and Nutrition Examination Survey (2010-2012)
Hae Jeong Lee, Sung Hoon Kim, Seo Heui Choi, Ju Suk Lee
SJR Q2Pediatric Gastroenterology Hepatology & NutritionOA

The present study showed that socioeconomic status might not an important risk factor for obesity in Korean children. These results warrant further studies to clarify the association between SES and obesity in Korean children.

Public Health, Environmental and Occupational HealthMedicine
15
Article|9 citations·2002
Factors Discriminating Nurses' Depression among Personal and Environmental Characteristics
Hae Jung Lee, Yong Sook Eo, Nam Hee Park, Gil Za Lee
Daehan ganho haghoeji

The purpose of this study was to examine the levels of depression experienced by Korean hospital nurses (N=198) and to identify discriminating factors of their depression experience among personal and environmental characteristics. Method: A cross-sectional survey design was used to answer the resea...

Leadership and ManagementNursing

Research Areas

Aerospace EngineeringMolecular MedicineGeneral Health ProfessionsPublic Health, Environmental and Occupational HealthGeneticsCardiology and Cardiovascular Medicine

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