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Ha Min Kim

Yonsei University · 医学

研究室紹介

Professor Ha Min Kim's research lab specializes in interdisciplinary biomedical and materials science research, focusing on probiotics and their functional properties in human and veterinary health, the synthesis and characterization of advanced nanomaterials such as III-V nanocrystals for optoelectronic applications, and innovative genomic technologies for spatially resolved analysis of cancer genomes. The lab also investigates the molecular mechanisms of disease through clinical and translational studies, including sepsis scoring systems and the impact of glaucoma medications on wound healing. These diverse research directions reflect a strong commitment to advancing both fundamental science and clinical applications.

probioticsnanomaterialsspatial genomicssepsis scoringwound healing

Research Overview

Papers
40
Total Citations
249
Papers (5y)
30
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
30total
2022
2023
2024
2025
2026
Citations per year (5y)
195total
20222023202420252026

Selected Papers

15
1
Article|73 citations·2024
Blood culture-free ultra-rapid antimicrobial susceptibility testing
Tae Hyun Kim, Jun‐Won Kang, Haewook Jang, Hyelyn Joo, Gi Yoon Lee, Hamin Kim, Untack Cho, Hyeeun Bang, Jisung Jang, Sangkwon Han, Dong Young Kim, Chan Mi Lee
SJR Q1Nature
Clinical BiochemistryBiochemistry, Genetics and Molecular Biology
2
Article|47 citations·2023
Beneficial, safety, and antioxidant properties of lactic acid bacteria: A next step in their evaluation as potential probiotics
Ronaldo Rwubuzizi, Hamin Kim, Wilhelm H. Holzapfel, Svetoslav Dimitrov Todorov
SJR Q1HeliyonOA

The role of lactic acid bacteria (LAB) as probiotics as health promoting factors for human or veterinary practice has gained increasing interest during the last three decades. This is reflected in screening approaches of LAB strains in line with minimal requirements for a "probiotic" with regard to safety and functionality. The latter might also include natural antioxidant properties, thereby constituting an additional benefit in substituting synthetic antioxidants. The in vitro antioxidant assa

Food ScienceAgricultural and Biological Sciences
3
Article|44 citations·2021
Tailored growth of single-crystalline InP tetrapods
Youngsik Kim, Hyekyoung Choi, Yeunhee Lee, Weon‐kyu Koh, Eunhye Cho, Tae‐Wan Kim, Hamin Kim, Yong‐Hyun Kim, Hu Young Jeong, Sohee Jeong
SJR Q1Nature CommunicationsOA

Despite the technological importance of colloidal covalent III-V nanocrystals with unique optoelectronic properties, their synthetic process still has challenges originating from the complex energy landscape of the reaction. Here, we present InP tetrapod nanocrystals as a crystalline late intermediate in the synthetic pathway that warrants controlled growth. We isolate tetrapod intermediate species with well-defined surfaces of (110) and ([Formula: see text]) via the suppression of further growt

Materials ChemistryMaterials Science
4
Article|16 citations·2022
Selection of Beneficial Bacterial Strains With Potential as Oral Probiotic Candidates
Hamin Kim, Joanna Ivy Irorita Fugaban, Wilhelm H. Holzapfel, Svetoslav Dimitrov Todorov
SJR Q2Probiotics and Antimicrobial Proteins
Food ScienceAgricultural and Biological Sciences
5
Article|13 citations·2023
Barcoded multiple displacement amplification for high coverage sequencing in spatial genomics
Jinhyun Kim, Sungsik Kim, Huiran Yeom, Seo Woo Song, Kyoungseob Shin, Sang-Wook Bae, Han Suk Ryu, Ji Young Kim, Ahyoun Choi, Sumin Lee, Taehoon Ryu, Yeongjae Choi
SJR Q1Nature CommunicationsOA

Determining mutational landscapes in a spatial context is essential for understanding genetically heterogeneous cell microniches. Current approaches, such as Multiple Displacement Amplification (MDA), offer high genome coverage but limited multiplexing, which hinders large-scale spatial genomic studies. Here, we introduce barcoded MDA (bMDA), a technique that achieves high-coverage genomic analysis of low-input DNA while enhancing the multiplexing capabilities. By incorporating cell barcodes dur

Cancer ResearchBiochemistry, Genetics and Molecular Biology
6
Article|10 citations·2023
Synthesis of Sequence-Controlled Homopolymer via Anionic Self-Alternating and Chemoselective Polymerization of 4-Vinyl-1,1-diphenylethylene Derivatives
Hamin Kim, Raita Goseki, Chihiro Homma, Takashi Ishizone
SJR Q1Macromolecules

Anionic polymerization of AB-type difunctional monomers derived from 4-vinyl-1,1-diphenylethylene ( VD ) bearing styrene and 1,1-diphenylethylene (DPE) frameworks was examined using diphenylmethylpotassium (Ph 2 CHK) in THF at −78 to 0 °C. A series of substituents including chloro ( ClVD ), methyl ( MeVD ), methoxy ( MeOVD ), and dimethylamino ( Me2NVD ) groups were introduced at the 4′-position of the VD framework to vary the polymerizability of VD . In each case, the resulting polymer was solu

Materials ChemistryMaterials Science
7
Article|8 citations·2025
Validation of the Phoenix Criteria for Sepsis and Septic Shock in a Pediatric Intensive Care Unit
C. Han, Hamin Kim, Mireu Park, Soo Yeon Kim, Jong Deok Kim, Myung Hyun Sohn, Seng Chan You, Kyung Won Kim
SJR Q2Journal of Korean Medical ScienceOA

The applicability of the Phoenix criteria and Phoenix Sepsis Score in higher-resource pediatric intensive care units (PICUs) outside the United States requires further validation. A retrospective cohort study analyzed electronic health records of 1,304 PICU admissions under 18 years old with suspected infection between February 2017 and December 2023. The score was calculated using two methods: 24-hour assessment, based on worst sub-scores within 24 hours of admission, and prompt assessment, usi

EpidemiologyMedicine
8
Article|5 citations·2023
Beneficial Properties and Evaluation of Survival in Model Systems of LAB Isolated from Oral Cavity
Hamin Kim, Ronaldo Rwubuzizi, Joanna Ivy Irorita Fugaban, Wilhelm H. Holzapfel, Svetoslav Dimitrov Todorov
SJR Q4Acta Microbiologica BulgaricaOA

In this study evaluation of the beneficial properties and survival for eight LAB putative probiotic strain was conducted including their ability to survive at different ox-bile concentrations and in the models representing different parts of digestive tract, ability to produce diacetyl, GABA and specific enzymes. The survival rates and release rates of the cells under the SSDP and AOS models were evaluated by encapsula¬tion using sodium alginate. Interaction between studied LAB and the pathogen

Food ScienceAgricultural and Biological Sciences
9
Article|5 citations·2021
Netarsudil-related Eyelid Wound Dehiscence
Ha Min Kim, Ann Q. Tran, Cameron Yang, Lora R. Dagi Glass
SJR Q1Journal of Glaucoma

An 81-year-old man with primary open-angle glaucoma on dorzolamide-timolol, bimatoprost and 0.02% netarsudil ophthalmic solution (Rhopressa), was found to have right lower lid basal cell carcinoma. The patient underwent Mohs surgery followed by repair of the right lower lid, with 3 episodes of wound dehiscence. When stopping netarsudil, appropriate granulation tissue was able to develop. While off netarsudil, the patient underwent Mohs resection of a left lower lid basal cell carcinoma, which wa

HematologyMedicine
10
Article|4 citations·2024
Predicting the Outcome of Pediatric Oral Food Challenges for Determining Tolerance Development
Hamin Kim, Kyunguk Jeong, Mireu Park, Yun Young Roh, Jae Hwa Jung, Soo Yeon Kim, Jong Deok Kim, Min Jung Kim, Yoon Hee Kim, Myung Hyun Sohn, Sooyoung Lee, Kyung Won Kim
SJR Q1Allergy Asthma and Immunology ResearchOA

Serum total IgE and food-specific IgE combined with age showed trends toward passing OFCs for confirming tolerance development. The constructed model may be used by clinicians as a practical guide for minimizing the risks of OFCs and a timely reintroduction for children with food allergies.

Immunology and AllergyMedicine
11
Article|4 citations·2022
I-LIFT (image-based laser-induced forward transfer) platform for manipulating encoded microparticles
Sumin Lee, Wooseok Lee, Amos Chungwon Lee, Juhong Nam, JinYoung Lee, Hamin Kim, Yunjin Jeong, Huiran Yeom, Namphil Kim, Seo Woo Song, Sunghoon Kwon
SJR Q2BiomicrofluidicsOA

Encoded microparticles have great potential in small-volume multiplexed assays. It is important to link the micro-level assays to the macro-level by indexing and manipulating the microparticles to enhance their versatility. There are technologies to actively manipulate the encoded microparticles, but none is capable of directly manipulating the encoded microparticles with homogeneous physical properties. Here, we report the image-based laser-induced forward transfer system for active manipulatio

Biomedical EngineeringEngineering
12
Article|3 citations·2016
Pontine Necrosis Related with Radiation Therapy, Complicated with Spontaneous Hemorrhage
Ha Min Kim, Bo Young Hong, Jong In Lee, Joon Sung Kim, Seong Hoon Lim
Brain & NeurorehabilitationOA
Biomedical EngineeringEngineering
13
Article|3 citations·2023
Highly Accurate Sequence- and Position-Independent Error Profiling of DNA Synthesis and Sequencing
Huiran Yeom, Namphil Kim, Amos Chungwon Lee, Jinhyun Kim, Hamin Kim, Hansol Choi, Seo Woo Song, Sunghoon Kwon, Yeongjae Choi
SJR Q1ACS Synthetic BiologyOA

A comprehensive error analysis of DNA-stored data during processing, such as DNA synthesis and sequencing, is crucial for reliable DNA data storage. Both synthesis and sequencing errors depend on the sequence and the transition of bases of nucleotides; ignoring either one of the error sources leads to technical challenges in minimizing the error rate. Here, we present a methodology and toolkit that utilizes an oligonucleotide library generated from a 10-base-shifted sequence array, which is indi

Molecular BiologyBiochemistry, Genetics and Molecular Biology
14
Article|2 citations·2025
Gadolinium oxide-decorated graphene oxide-based dual-stimuli-responsive smart fluids
Hyukjoon Gwon, Hamin Kim, Seungae Lee
SJR Q1Nanoscale

Gadolinium oxide-based compounds are employed for the first time in the fabrication of dual-stimuli-responsive smart fluids that respond to both electric and magnetic fields.

Biomedical EngineeringEngineering
15
Article|2 citations·2020
Local Glaucomatous Defects of the Circumpapillary Retinal Nerve Fiber Layer Show a Variety of Patterns of Progression
Ha Min Kim, William Eugene McKee, Katarzyna Malendowicz, Abinaya Thenappan, Emmanouil Tsamis, Melvi Eguia, Carlos Gustavo De Moraes, Robert Ritch, Donald C. Hood
SJR Q1Journal of GlaucomaOA

PRECIS: The region of glaucomatous progression, seen on optical coherence tomography (OCT) images of the circumpapillary retinal nerve fiber layer (cRNFL), increases in width and depth in all eyes, but shows a variety of different patterns of loss across eyes. PURPOSE: The purpose of this study was to examine the patterns of cRNFL loss secondary to glaucomatous progression in a region associated with the superior hemifield of the 24-2/30-2 visual field (VF). METHODS: Twenty-four eyes (20 patient

OphthalmologyMedicine

Research Areas

Biomedical EngineeringOphthalmologyClinical BiochemistryFood ScienceMaterials ChemistryEpidemiology

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