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Han Gil Seo

Seoul National University · 医学

研究室紹介

Professor Han Gil Seo's research lab specializes in neurorehabilitation and brain plasticity, focusing on innovative, technology-driven interventions for stroke and neurodegenerative disorders. The lab explores the therapeutic potential of fully immersive virtual reality (VR), transcranial direct current stimulation (tDCS), and robotic-assisted gait training to enhance motor and cognitive recovery in patients with stroke and Parkinson’s disease. A key emphasis is placed on improving functional outcomes through personalized, engaging, and evidence-based rehabilitation strategies that leverage advanced technologies and enriched environments. The lab also investigates the neural mechanisms underlying recovery, aiming to bridge clinical practice with neuroscience research.

virtual reality rehabilitationneurorehabilitationtDCSParkinson's diseasestroke recovery

Research Overview

Papers
187
Total Citations
2,575
Papers (5y)
63
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
63total
2021
2022
2023
2024
2025
Citations per year (5y)
537total
20212022202320242025

Selected Papers

15
1
Article|97 citations·2019
Upper Extremity Rehabilitation Using Fully Immersive Virtual Reality Games With a Head Mount Display: A Feasibility Study
Seung Hak Lee, Hae‐Yoon Jung, Seo Jung Yun, Byung‐Mo Oh, Han Gil Seo
SJR Q1PM&R

BACKGROUND: Rehabilitation therapy using a virtual reality (VR) system for stroke patients has gained attention. However, few studies have investigated fully immersive VR using a head-mount display (HMD) for upper extremity rehabilitation in stroke patients. OBJECTIVE: To investigate the feasibility, preliminary efficacy, and usability of a fully immersive VR rehabilitation program using a commercially available HMD for upper-limb rehabilitation in stroke patients. DESIGN: A feasibility study. S

RehabilitationMedicine
2
Article|78 citations·2021
Risk and mortality of aspiration pneumonia in Parkinson’s disease: a nationwide database study
Jun Hee Won, Seong Jun Byun, Byung‐Mo Oh, Sang Jun Park, Han Gil Seo
SJR Q1Scientific ReportsOA

This retrospective cohort study investigated the risk and mortality rate due to aspiration pneumonia in patients with Parkinson's disease (PD) using a nationwide database. We identified 10,159 newly diagnosed PD patients between 2004 and 2006, and four age- and sex-matched controls for each PD patient from the National Health Insurance Service database in Korea. We analyzed the relative risk of aspiration pneumonia and mortality after the first occurrence of aspiration pneumonia until 2017. Thro

Speech and HearingHealth Professions
3
Article|72 citations·2017
Robotic-assisted gait training combined with transcranial direct current stimulation in chronic stroke patients: A pilot double-blind, randomized controlled trial
Han Gil Seo, Woo Hyung Lee, Seung Hak Lee, Youbin Yi, Kwang Dong Kim, Byung‐Mo Oh
SJR Q3Restorative Neurology and Neuroscience

BACKGROUND: Although robotic-assisted gait training (RAGT) is becoming a standard method in stroke rehabilitation, its effect on chronic stroke patients is uncertain. OBJECTIVE: This study aimed to investigate whether anodal transcranial direct current stimulation (tDCS) enhances the effect of RAGT on functional ambulation in chronic stroke patients. METHODS: Chronic hemiplegic stroke patients with a Functional Ambulatory Category (FAC) score≤4 were randomly assigned to either the RAGT with anod

NeurologyNeuroscience
4
Article|69 citations·2020
Cognitive Training Using Fully Immersive, Enriched Environment Virtual Reality for Patients With Mild Cognitive Impairment and Mild Dementia: Feasibility and Usability Study
Seo Jung Yun, Min‐Gu Kang, Dongseok Yang, Younggeun Choi, Heejae Kim, Byung‐Mo Oh, Han Gil Seo
SJR Q1JMIR Serious GamesOA

BACKGROUND: Cognitive training using virtual reality (VR) may result in motivational and playful training for patients with mild cognitive impairment and mild dementia. Fully immersive VR sets patients free from external interference and thus encourages patients with cognitive impairment to maintain selective attention. The enriched environment, which refers to a rich and stimulating environment, has a positive effect on cognitive function and mood. OBJECTIVE: The aim of this study was to invest

Human-Computer InteractionComputer Science
5
Article|57 citations·2015
Swallowing Kinematics and Factors Associated with Laryngeal Penetration and Aspiration in Stroke Survivors with Dysphagia
Han Gil Seo, Byung‐Mo Oh, Tai Ryoon Han
SJR Q1Dysphagia
Speech and HearingHealth Professions
6
Article|48 citations·2023
Fully immersive virtual reality exergames with dual-task components for patients with Parkinson’s disease: a feasibility study
Seo Jung Yun, Sung Eun Hyun, Byung‐Mo Oh, Han Gil Seo
SJR Q1Journal of NeuroEngineering and RehabilitationOA

BACKGROUND: Dual-task training in Parkinson's disease (PD) improves spatiotemporal gait parameters, cognition, and quality of life. Virtual reality (VR) has been used as a therapeutic tool for patients to participate in activities in a safe environment, engage in multisensory experiences, and improve motivation and interest in rehabilitation. This study aimed to investigate the feasibility of fully immersive VR exergames with dual-task components in patients with PD. METHODS: We developed VR exe

Physical Therapy, Sports Therapy and RehabilitationHealth Professions
7
Article|46 citations·2010
Early Motor Balance and Coordination Training Increased Synaptophysin in Subcortical Regions of the Ischemic Rat Brain
Han Gil Seo, Dae Yul Kim, Hee Won Park, Shi-Uk Lee, Sung‐Hye Park
SJR Q2Journal of Korean Medical ScienceOA

The aim of this study was to evaluate the effect of early motor balance and coordination training on functional recovery and brain plasticity in an ischemic rat stroke model, compared with simple locomotor exercise. Adult male Sprague-Dawley rats with cortical infarcts were trained under one of four conditions: nontrained control, treadmill training, motor training on the Rota-rod, or both Rota-rod and treadmill training. All types of training were performed from post-operation day 1 to 14. Neur

Developmental NeuroscienceNeuroscience
8
Article|43 citations·2022
Robot-assisted gait training with auditory and visual cues in Parkinson's disease: A randomized controlled trial
Heejae Kim, Eunkyung Kim, Seo Jung Yun, Min‐Gu Kang, Hyun Iee Shin, Byung‐Mo Oh, Han Gil Seo
SJR Q1Annals of Physical and Rehabilitation Medicine
Physical Therapy, Sports Therapy and RehabilitationHealth Professions
9
Article|41 citations·2010
Early Motor Balance and Coordination Training Increased Synaptophysin in Subcortical Regions of the Ischemic Rat Brain
서한길, 김대열, 박희원, 이시욱, 박성혜
Journal of Korean Medical Science

The aim of this study was to evaluate the effect of early motor balance and coordination training on functional recovery and brain plasticity in an ischemic rat stroke model,compared with simple locomotor exercise. Adult male Sprague-Dawley rats with cortical infarcts were trained under one of four conditions: nontrained control, treadmill training,motor training on the Rota-rod, or both Rota-rod and treadmill training. All types of training were performed from post-operation day 1 to 14. Neurol

10
Article|39 citations·2021
Exercise Management Using a Mobile App in Patients With Parkinsonism: Prospective, Open-Label, Single-Arm Pilot Study
Aram Kim, Seo Jung Yun, Kwan-Sik Sung, Yeonju Kim, Ju Young Jo, Hanseul Cho, Kyudong Park, Byung‐Mo Oh, Han Gil Seo
SJR Q1JMIR mhealth and uhealthOA

BACKGROUND: Patients with parkinsonism have higher inactivity levels than the general population, and this results in increased comorbidities. Although exercise has benefits for motor function and quality of life (QOL) in patients with parkinsonism, these patients face many barriers to exercise participation, such as lack of motivation, fatigue, depression, and time constraints. Recently, the use of mobile apps has been highlighted as a remote exercise management strategy for patients with chron

NeurologyMedicine
11
Article|37 citations·2017
Grip Strength on the Unaffected Side as an Independent Predictor of Functional Improvement After Stroke
Youbin Yi, Jae Seong Shim, Byung‐Mo Oh, Han Gil Seo
SJR Q1American Journal of Physical Medicine & Rehabilitation

The current study suggests for the first time that grip strength on the unaffected side is an independent predictor for short-term functional gain and outcome after stroke. This result may change post-stroke rehabilitation strategies to emphasize exercises to prevent loss of muscle strength. In addition, this implies the possibility of a relationship between sarcopenia and post-stroke function. Further research is needed to reveal the effect of sarcopenia on stroke patients and its mechanism.

PhysiologyMedicine
12
Article|30 citations·2010
Longitudinal Changes of the Swallowing Process in Subacute Stroke Patients with Aspiration
Han Gil Seo, Byung‐Mo Oh, Tai Ryoon Han
SJR Q1Dysphagia
Speech and HearingHealth Professions
13
Article|28 citations·2019
Effects of robot-assisted gait training in patients with Parkinson’s disease: study protocol for a randomized controlled trial
Min‐Gu Kang, Seo Jung Yun, Hyun Iee Shin, Eunkyung Kim, Hyun Haeng Lee, Byung‐Mo Oh, Han Gil Seo
SJR Q2TrialsOA

BACKGROUND: Robot-assisted gait training (RAGT) was developed to restore gait function by promoting neuroplasticity through repetitive locomotor training and has been utilized in gait training. However, contradictory outcomes of RAGT have been reported for patients with Parkinson's disease (PD). In addition, the mechanism of the RAGT treatment effect is still unknown. This study aims to investigate the effects of RAGT on gait velocity in patients with PD and to unveil the mechanisms of these eff

Physical Therapy, Sports Therapy and RehabilitationHealth Professions
14
Article|25 citations·2020
Pneumonia risk and its associated factors in Parkinson's disease: A National Database Study
Jun Hee Won, Seong Jun Byun, Byung‐Mo Oh, Han‐Joon Kim, Sang Jun Park, Han Gil Seo
SJR Q1Journal of the Neurological Sciences
NeurologyMedicine
15
Review|25 citations·2023
A Systematic Review of the Learning Dynamics of Proprioception Training: Specificity, Acquisition, Retention, and Transfer
Han Gil Seo, Seo Jung Yun, Andria J. Farrens, Christopher A. Johnson, David J. Reinkensmeyer
SJR Q1Neurorehabilitation and neural repairOA

OBJECTIVE: We aimed to identify key aspects of the learning dynamics of proprioception training including: 1) specificity to the training type, 2) acquisition of proprioceptive skills, 3) retention of learning effects, and 4) transfer to different proprioceptive skills. METHODS: We performed a systematic literature search using the database (MEDLINE, EMBASE, Cochrane Library, and PEDro). The inclusion criteria required adult participants who underwent any training program that could enhance prop

NeurologyNeuroscience

Research Areas

Speech and HearingNeurologyRehabilitationCognitive NeuroscienceSurgeryPhysiology

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