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Hee Yoon

Yonsei University · 医学

研究室紹介

Professor Hee Yoon's research lab specializes in translational biomedical engineering and emergency medicine, focusing on advancing diagnostic and therapeutic technologies for critical care. The lab investigates nanoformulated drug delivery systems, particularly nanoemulsions, to enhance drug efficacy and safety, while also exploring AI-driven ultrasound applications for real-time cardiovascular assessment during resuscitation. A significant portion of the research is dedicated to understanding and predicting severe respiratory complications in infectious diseases such as adenovirus pneumonia, especially in young, healthy populations. The lab integrates clinical data with innovative imaging and artificial intelligence to improve emergency decision-making and patient outcomes.

nanoemulsionsadenovirus pneumoniapoint-of-care ultrasoundAI in emergency medicineresuscitation

Research Overview

Papers
95
Total Citations
1,294
Papers (5y)
50
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
50total
2021
2022
2023
2024
2025
Citations per year (5y)
250total
20212022202320242025

Selected Papers

15
1
Article|230 citations·2016
Neutrophil-to-lymphocyte ratio as a prognostic marker in critically-ill septic patients
Sung Yeon Hwang, Tae Gun Shin, Ik Joon Jo, Kyeongman Jeon, Gee Young Suh, Tae Rim Lee, Hee Yoon, Won Chul, Min Seob Sim
SJR Q1The American Journal of Emergency Medicine
EpidemiologyMedicine
2
Article|117 citations·2017
Low Accuracy of Positive qSOFA Criteria for Predicting 28-Day Mortality in Critically Ill Septic Patients During the Early Period After Emergency Department Presentation
Sung Yeon Hwang, Ik Joon Jo, Se Uk Lee, Tae Rim Lee, Hee Yoon, Won Chul, Min Seob Sim, Tae Gun Shin
SJR Q1Annals of Emergency Medicine
EpidemiologyMedicine
3
Article|54 citations·2019
N95 filtering facepiece respirators do not reliably afford respiratory protection during chest compression: A simulation study
Sung Yeon Hwang, Hee Yoon, Aerin Yoon, Taerim Kim, Gun Tak Lee, Kwang Yul Jung, Joo Hyun Park, Tae Gun Shin, Won Chul, Min Seob Sim, Seonwoo Kim
SJR Q1The American Journal of Emergency Medicine
Emergency MedicineMedicine
4
Article|42 citations·2018
Cytotoxicity Evaluation of Turmeric Extract Incorporated Oil-in-Water Nanoemulsion
Hee Yoon, Xiaowei Zhang, Min-Hee Kang, Gyeong Sun Kim, Sun Hae Ra Shin, Sang Hong Baek, Bom Nae Lee, Su Jung Hong, Jun Kim, Kwonho Hong, Hojae Bae
SJR Q1International Journal of Molecular SciencesOA

To overcome the drawbacks of conventional drug delivery system, nanoemulsion have been developed as an advanced form for improving the delivery of active ingredients. However, safety evaluation is crucial during the development stage before the commercialization. Therefore, the aim of this study was to evaluate the cytotoxicity of two types of newly developed nanoemulsions. Turmeric extract-loaded nanoemulsion powder-10.6 (TE-NEP-10.6, high content of artificial surfactant Tween 80), which forms

Pharmaceutical SciencePharmacology, Toxicology and Pharmaceutics
5
Article|37 citations·2016
Clinical characteristics and factors predicting respiratory failure in adenovirus pneumonia
Hee Yoon, Byung Woo Jhun, Se Jin Kim, Kang Kim
SJR Q1RespirologyOA

BACKGROUND AND OBJECTIVE: Limited data exist regarding factors predicting respiratory failure (RF) in non-immunocompromised patients with adenovirus (AdV) pneumonia. METHODS: We described characteristics of AdV pneumonia (n = 91) versus non-AdV pneumonia (n = 55) and compared clinico-laboratory and radiological characteristics in patient groups categorized by RF. RESULTS: All 91 AdV pneumonia patients presented with acute respiratory symptoms and radiological infiltrations and had significantly

GeneticsBiochemistry, Genetics and Molecular Biology
6
Article|33 citations·2022
Point-of-care ultrasound compression of the carotid artery for pulse determination in cardiopulmonary resuscitation
Soo Yeon Kang, Ik Joon Jo, Gun Tak Lee, Jong Eun Park, Taerim Kim, Se Uk Lee, Sung Yeon Hwang, Tae Gun Shin, Kyunga Kim, Ji Sun Shim, Hee Yoon
SJR Q1Resuscitation
Emergency MedicineMedicine
7
Article|28 citations·2017
Characteristics of Adenovirus Pneumonia in Korean Military Personnel, 2012–2016
Hee Yoon, Byung Woo Jhun, Hojoong Kim, Hongseok Yoo, Sung Bum Park
SJR Q2Journal of Korean Medical ScienceOA

Adenovirus (AdV) can cause severe pneumonia in non-immunocompromised host, but limited data exist on the distinctive characteristics of AdV pneumonia in non-immunocompromised patients. We evaluated distinctive clinico-laboratory and radiological characteristics and outcomes of AdV pneumonia (n = 179), compared with non-AdV pneumonia (n = 188) in Korean military personnel between 2012 and 2016. AdV pneumonia patients had a higher rate of consolidation with ground-glass opacity (101/152) in lobar

Infectious DiseasesMedicine
8
Article|25 citations·2019
Usefulness of Protocolized Point-of-Care Ultrasonography for Patients with Acute Renal Colic Who Visited Emergency Department: A Randomized Controlled Study
Seok Goo Kim, Ik Joon Jo, Taerim Kim, Sung Yeon Hwang, Joo Hyun Park, Tae Gun Shin, Min Seob Sim, Won Chul Cha, Hee Yoon
SJR Q2MedicinaOA

Background and Objectives: Ultrasonography is useful in evaluating patients with renal colic and it has high sensitivity and specificity for diagnosing ureter stones by revealing hydronephrosis. We evaluated the efficacy of point-of-care ultrasonography protocol in managing patients with acute renal colic who visited the emergency department (ED). Materials and Methods: Between March 2019 and July 2019, patients who visited the ED because of renal colic were randomly assigned by date of visit ei

Pulmonary and Respiratory MedicineMedicine
9
Article|21 citations·2020
Are loose-fitting powered air-purifying respirators safe during chest compression? A simulation study
Soo Hyun Park, Sung Yeon Hwang, Gun Tak Lee, Jong Eun Park, Taerim Kim, Tae Gun Shin, Min Seob Sim, Ik Joon Jo, Seonwoo Kim, Hee Yoon
SJR Q1The American Journal of Emergency MedicineOA
Emergency MedicineMedicine
10
Article|18 citations·2018
Quality Improvement Program Outcomes for Endotracheal Intubation in the Emergency Department
Sung Yeon Hwang, Joo Hyun Park, Hee Yoon, Won Chul Cha, Ik Joon Jo, Min Seob Sim, Keun Jeong Song, Hyo Jung Woo, Sung Geun Jeong, Tae Gun Shin
SJR Q1Journal of Patient Safety

OBJECTIVES: We describe our 3-year experience with endotracheal intubation (ETI) outcomes during a multidisciplinary emergency department (ED)-based quality improvement (QI) program. METHODS: This was a single-center, observational study taking place during a QI program. We used a registry for airway management performed in the ED from April 2014 to February 2017. The QI program focused on procedural standardization, airway management education, and comprehensive preparation of airway equipment.

Anesthesiology and Pain MedicineMedicine
11
Article|9 citations·2024
Artificial intelligence-based evaluation of carotid artery compressibility via point-of-care ultrasound in determining the return of spontaneous circulation during cardiopulmonary resuscitation
Subin Park, Hee Yoon, Soo Yeon Kang, Ik Joon Jo, Sejin Heo, Hansol Chang, Jong Eun Park, Gun Tak Lee, Taerim Kim, Sung Yeon Hwang, So‐Young Park, Myung Jin Chung
SJR Q1ResuscitationOA

RealCAC-Net enabled precise CAC quantification for ROSC determination during cardiopulmonary resuscitation. Future research should integrate this AI-enhanced ultrasound approach to revolutionize emergency care.

Emergency MedicineMedicine
12
Article|9 citations·2022
Online Learning versus Hands-On Learning of Basic Ocular Ultrasound Skills: A Randomized Controlled Non-Inferiority Trial
Soo Yeon Kang, Jonghoon Yoo, Soo‐Kyung Park, Ik-Joon Jo, Seonwoo Kim, Hyun Cho, Gun Tak Lee, Jong-Eun Park, Taerim Kim, Se-Uk Lee, Sung Yeon Hwang, Wonchul Cha
SJR Q2MedicinaOA

Background and objectives: Ocular ultrasound is a core application of point-of-care ultrasound (POCUS) to assist physicians in promptly identifying various ocular diseases at the bedside; however, hands-on POCUS training is challenging during a pandemic. Materials and Methods: A randomized controlled non-inferiority trial was conducted in an academic emergency department from October 2020 to April 2021. Thirty-two participants were randomly assigned to one of two groups. Group H (hands-on learni

Critical Care and Intensive Care MedicineMedicine
13
Article|6 citations·2018
Ketamine use for endotracheal intubation in severe sepsis and septic shock
SEOK WOO JO, SUNG YEON HWANG, Ik Joon Jo, T.R. Lee, Hee Yoon, WON CHUL CHA, Min Seob Sim, Tae Gun Shin
SJR Q3Signa VitaeOA

Objective. We conducted this study to evaluate the clinical outcomes of patients with severe sepsis and septic shock who were treated with ketamine for endotra-cheal intubation.Methods. A single-center, retrospective study was carried out to compare the out-comes of patients with severe sepsis and septic shock who received a ketamine or non-ketamine agent for rapid sequence intubation (RSI). We analyzed the sepsis registry for adult patients who presented to the emergency department (ED), met th

Critical Care and Intensive Care MedicineMedicine
14
Article|5 citations·2021
The effect of norepinephrine on common carotid artery blood flow in septic shock patients
Seok Goo Kim, Ik Joon Jo, Soo Yeon Kang, Jonghoon Yoo, Gun Tak Lee, Jong Eun Park, Taerim Kim, Sung Yeon Hwang, Won Chul Cha, Tae Gun Shin, Heewon Han, Hee Yoon
SJR Q1Scientific ReportsOA

Abstract This study was designed to evaluate the hemodynamic effect of norepinephrine (NE) on the peak systolic velocity (PSV), diameter, and blood flow of the common carotid artery (CCA) using the point-of-care ultrasound (POCUS) in patients with septic shock. The study involved patients above 18 years old with septic shock. Arterial monitoring, carotid ultrasonography, and transthoracic echocardiography were performed before NE administration (T 0 ). When the mean arterial pressure exceeded 65

SurgeryMedicine
15
Article|4 citations·2015
The Utility of Thoracic Ultrasound in Patients with Acute Eosinophilic Pneumonia
Hee Yoon, Se Jin Kim, Kang Kim, Ji Eun Lee, Byung Woo Jhun
SJR Q1PLoS ONEOA

Thoracic ultrasound (TUS) is an easy-to-use imaging modality that aids physicians in the differential diagnosis of respiratory diseases. However, no data exist on the TUS findings of acute eosinophilic pneumonia (AEP) or their clinical utility in patients with AEP. Thus, we performed an observational study on TUS findings and their clinical utility for follow-up in patients with AEP. We prospectively screened patients who visited the emergency department for acute respiratory symptoms at the Arm

Critical Care and Intensive Care MedicineMedicine

Research Areas

Emergency MedicineEpidemiologyCritical Care and Intensive Care MedicineCardiology and Cardiovascular MedicinePulmonary and Respiratory MedicineAnesthesiology and Pain Medicine

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