Heung Jae Lee
Sungkyunkwan University · 医学
研究室紹介
Professor Heung Jae Lee's research lab specializes in pediatric and congenital cardiovascular diseases, with a strong focus on advanced medical imaging techniques such as MRI and MDCT for accurate diagnosis and evaluation of complex congenital heart defects. The lab investigates rare and critical postoperative complications like chylothorax and unroofed coronary sinus syndrome, emphasizing innovative conservative treatments such as somatostatin therapy. Additionally, the lab contributes to epidemiological studies on congenital heart disease and Kawasaki disease in the Korean population, highlighting regional variations and long-term outcomes. Their work bridges clinical cardiology, radiology, and public health to improve patient management and outcomes in pediatric cardiac care.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Magnetic resonance is an effective modality in depicting TAPVCs.
Pregnancy outcomes in patients with congenital heart disease have not been fully assessed in Korea. Forty-nine pregnancies that occurred in 34 women with congenital heart disease who registered at our hospital between September 1995 and April 2006 were reviewed. Spontaneous abortions occurred in two pregnancies at 6+1 and 7 weeks, and another two underwent elective pregnancy termination. One maternal death in puerperium occurred in a woman with Eisenmenger syndrome. Maternal cardiac complication
BACKGROUND: The aim of this study was to investigate the incidence rate and epidemiologic patterns of Kawasaki disease in Korea for a 3 year period during 2000 to 2002. METHODS: An epidemiologic survey on Kawasaki disease was retrospectively performed. The questionnaire was sent to all 112 hospitals having pediatric residency programs, and obtained data were analyzed. RESULTS: The 9150 cases of Kawasaki disease from 92 hospitals which responded (response rate, 82.1%) included 5515 males and 3635
Chylothorax is a rare but serious postoperative condition with a high rate of morbidity that may lead to death of children with congenital heart disease. Here we reviewed nine consecutive cases with chylothorax in infants and children following cardiac surgery from March 2002 to February 2003. Somatostatin was added to conservative treatment protocol to increase effectiveness of therapy in all cases. The duration of somatostatin therapy varied from 7 to 32 days. All cases of chylothorax were suc
We performed a retrospective epidemiologic survey on Kawasaki disease (KD) from 1997 to 1999 in Korea. We sent a questionnaire to 111 training hospitals, and summarized the data from 50 hospitals that responded. Data from a total of 3,862 cases were collected, which showed no difference in annual incidence and a seasonal predilection for summer. The male-to-female ratio was 1.51:1, and the mean age was 29.7 months. The prevalence of sibling cases was 0.26%, and the rate of recurrent cases was 2.
Recently, a revised Ghent nosology has been established for the diagnosis of Marfan syndrome (MFS) that puts more weight on the aortic root aneurysm and ectopia lentis. We compared the application of the Ghent and revised Ghent nosologies in adult Korean patients for whom there is suspicion of MFS. From January 1995 to June 2010, we enrolled 106 patients older than 20 years for whom there was suspicion of MFS, and who had undergone genetic analysis of the fibrillin-1 gene (FBN1). Of 106 patients
Poly(1-phenylpenta-1,3-diyn-5-ol)(PPDO), prepared by NbCl5/(Bun)4Sn catalysed metathesis of PDO, is converted into a graphite-like structure with a high conductivity in the absence of dopants by heat treatment at 800 °C under vacuum.
1938년 Dr. Gross에 의한 동맥관 개존 결찰 및 1945년 Blalock과 Taussig의 활로씨 4징 단락 수술 로 세인의 주목을 받기 시작한 심장 수술은, 1954년 Gibbon이 인공심폐기를 심장 수술에 사용하기 시작하 면서 개심술이 보편화되는 계기를 맞게 되었다. 그 후 비교적 짧은 역사에도 불구하고 선천성 심장병, 특 히 복합 심장기형에 대한 수술과 신생아 및 영아기 심장 수술은 급속히 발전하였고, 통상적인 교정이 불 가능한 심장병에 대하여서는 심장이식 및 심폐이식이 영아 및 소아에서도 널리 이용되기 시작하였다. 혈역학적 정보를 보다 정확히 알수 있는 심도자법이 사람에서 시작된 것은 1929년으로, Dr. Forssmann이 스 스로 자신의 혈관에 도자를 넣고 우심 도자를 시행함으로 써 이 검사가 안전하게 시행될 수 있음을 발표하였으나, 임상에 적용되기 시작한 것은 이보다 약 20년 후로 심장 수술이 활발해지기 시작한 이후이다. 혈관조영술은 1938 년 Castel
tional catheterization)은 풍선도자나 stent를 이용하여 좁은 부분을 넓혀주거나, 불필요한 혈관이나 동맥관 개 존, 심방 중격 결손 등 이상 연결을 특수 기구로 막아주 는 새로운 치료 방식으로, 이미 많은 경우 수술을 대신하 거나 수술의 보조 수단으로 정착되고 있다. 특히 폐동맥 협착(PS)의 경우에는 수술치료 대신 풍선 판막성형술이 기본적인 치료법으로 자리잡은 지 오래 되었으며, 수술 의 상흔이 없다는 매력 때문에 동맥관 개존(PDA)이나 심방 중격 결손(ASD)을 갖고 있는 여아에서는 retrievable coil이나 Cardio-Seal, Amplatzer Septal Occluder 등 특수 기구를 이용하여 이를 치료하는 경우가 늘어나고 있다. 우리나라에서 본격적으로 선천성 심질환에서 수술을 대신하여 심도자 시술이 시작된 것은 1985년으로 윤 등 과 이 등에 의한 폐동맥 협착에서의 풍선 판막성형술 로, 지금은 필자의 병원을 포함하여 주요 심장센터 소아 과