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Hoyong Chung

Kyung Hee University · 生化学・遺伝学・分子生物学

研究室紹介

Professor Hoyong Chung's research lab focuses on plant molecular biology and biotechnology, with a strong emphasis on understanding the genetic and molecular mechanisms underlying fruit quality, stress tolerance, and innate immunity in crops. The lab investigates key regulatory genes and non-coding RNAs—such as miRNAs and antimicrobial peptides—in model and economically important plants like rice, pear, and Prunus species. Using advanced genome editing tools like CRISPR/Cas9, the lab explores gene function in abiotic stress responses (e.g., drought and salinity) and pathogen defense, aiming to develop resilient and high-quality crop varieties. Their work bridges fundamental molecular biology with translational applications in agricultural biotechnology.

fruit qualitystress toleranceCRISPR genome editingantimicrobial peptidesmiRNA function

Research Overview

Papers
39
Total Citations
437
Papers (5y)
19
Primary Field
生化学・遺伝学・分子生物学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
19total
2020
2021
2022
2023
2024
Citations per year (5y)
231total
20202021202220232024

Selected Papers

15
1
Review|56 citations·2021
Molecular Insights of Fruit Quality Traits in Peaches, Prunus persica
Karpagam Veerappan, Sathishkumar Natarajan, Hoyong Chung, Junhyung Park
SJR Q1PlantsOA

Fleshy fruits are the most demanded fruits because of their organoleptic qualities and nutritional values. The genus Prunus is a rich source of diversified stone/drupe fruits such as almonds, apricots, plums, sweet cherries, peaches, and nectarines. The fruit-ripening process in Prunus involves coordinated biochemical and physiological changes resulting in changes in fruit texture, aroma gain, color change in the pericarp, sugar/organic acid balance, fruit growth, and weight gain. There are diff

Plant ScienceAgricultural and Biological Sciences
2
Article|54 citations·2014
Geminivirus AL2 protein induces expression of, and interacts with, a calmodulin-like gene, an endogenous regulator of gene silencing
Hoyong Chung, Gabriela Lacatus, Garry Sunter
SJR Q2Virology
Plant ScienceAgricultural and Biological Sciences
3
Article|50 citations·2011
Expression of a recombinant chimeric protein of hepatitis A virus VP1-Fc using a replicating vector based on Beet curly top virus in tobacco leaves and its immunogenicity in mice
Hoyong Chung, Hyun Ho Lee, Kyung Il Kim, Ha Young Chung, Jeon Hwang‐Bo, Jong Hwa Park, Garry Sunter, Jong Bum Kim, Dong Hwa Shon, Wonyong Kim, In Sik Chung
SJR Q1Plant Cell Reports
BiotechnologyBiochemistry, Genetics and Molecular Biology
4
Article|40 citations·2020
Efficiency of Recombinant CRISPR/rCas9-Mediated miRNA Gene Editing in Rice
Pil Joong Chung, Hoyong Chung, Nuri Oh, JooHee Choi, Seung Woon Bang, Se Eun Jung, Harin Jung, Jae Sung Shim, Ju‐Kon Kim
SJR Q1International Journal of Molecular SciencesOA

Drought is one of the major environmental stresses adversely affecting crop productivity worldwide. Precise characterization of genes involved in drought response is necessary to develop new crop varieties with enhanced drought tolerance. Previously, we identified 66 drought-induced miRNAs in rice plants. For the further functional investigation of the miRNAs, we applied recombinant codon-optimized Cas9 (rCas9) for rice with single-guide RNAs specifically targeting mature miRNA sequences or site

Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
Article|22 citations·2021
Transcriptomic Analysis of Rice Plants Overexpressing PsGAPDH in Response to Salinity Stress
Hyemin Lim, Hyun‐Ju Hwang, Tae‐Lim Kim, So-Young Kim, Hoyong Chung, Daewoo Lee, Soo Rin Kim, Soochul Park, Woosuk Cho, Hyeonso Ji, Gang‐Seob Lee
SJR Q2GenesOA

In plants, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a main enzyme in the glycolytic pathway. It plays an essential role in glycerolipid metabolism and response to various stresses. To examine the function of PsGAPDH (Pleurotus sajor-caju GAPDH) in response to abiotic stress, we generated transgenic rice plants with single-copy/intergenic/homozygous overexpression PsGAPDH (PsGAPDH-OX) and investigated their responses to salinity stress. Seedling growth and germination rates of PsGAPDH-

Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
Article|22 citations·2014
Altered expression of Arabidopsis genes in response to a multifunctional geminivirus pathogenicity protein
Lu Liu, Hoyong Chung, Gabriela Lacatus, Surendranath Baliji, Jianhua Ruan, Garry Sunter
SJR Q1BMC Plant BiologyOA

BACKGROUND: Geminivirus AC2 is a multifunctional protein that acts as a pathogenicity factor. Transcriptional regulation by AC2 appears to be mediated through interaction with a plant specific DNA binding protein, PEAPOD2 (PPD2), that specifically binds to sequences known to mediate activation of the CP promoter of Cabbage leaf curl virus (CaLCuV) and Tomato golden mosaic virus (TGMV). Suppression of both basal and innate immune responses by AC2 in plants is mediated through inactivation of SnRK

Plant ScienceAgricultural and Biological Sciences
7
Article|20 citations·2010
Simultaneous suppression of three genes related to brassinosteroid (BR) biosynthesis altered campesterol and BR contents, and led to a dwarf phenotype in Arabidopsis thaliana
Hoyong Chung, Shozo Fujioka, Sunghwa Choe, So‐Youn Lee, Youn Hyung Lee, Nam In Baek, In Sik Chung
SJR Q1Plant Cell Reports
Plant ScienceAgricultural and Biological Sciences
8
Article|19 citations·2014
Interaction between the transcription factor AtTIFY4B and begomovirus AL2 protein impacts pathogenicity
Hoyong Chung, Garry Sunter
SJR Q1Plant Molecular Biology
Plant ScienceAgricultural and Biological Sciences
9
Article|16 citations·2019
Development of the chloroplast genome-based InDel markers in Niitaka (Pyrus pyrifolia) and its application
Hoyong Chung, So Youn Won, Yoon-Kyung Kim, Jung‐Sun Kim
SJR Q2Plant Biotechnology ReportsOA

Pears ( Pyrus spp.) are one of the most important fruit crops in temperate regions and are self-incompatible. Large numbers of interspecific hybrids occur naturally and, have been artificially produced in breeding programs. Also, many pear cultivars were generated from intraspecific crossing. Some varieties have been cultivated for a long time, but their breeding history remains unknown. The P. pyrifolia cv. Niitaka is one of key varieties in the Korean pear breeding program. Therefore, its comp

Plant ScienceAgricultural and Biological Sciences
10
Article|14 citations·2020
Transcriptome Analysis of Psacothea hilaris: De Novo Assembly and Antimicrobial Peptide Prediction
Joon Ha Lee, Hoyong Chung, Yong Pyo Shin, In-Woo Kim, Sathishkumar Natarajan, Karpagam Veerappan, Minchul Seo, Junhyung Park, Jae Sam Hwang
SJR Q1InsectsOA

Antimicrobial peptides (AMPs) are the frontline innate defense system evolutionarily preserved in insects to combat invading pathogens. These AMPs could serve as an alternative to classical antibiotics to overcome the burden of treating multidrug resistant bacteria. Psacotheasin, a knottin type AMP was isolated from Psacothea hilaris and shown to exhibit antimicrobial activity, especially against fungi through apoptosis mediated cell death. In this study, we aimed to identify novel probable AMPs

MicrobiologyImmunology and Microbiology
11
Article|13 citations·2022
Identification of Potential Cytochrome P450 3A5 Inhibitors: An Extensive Virtual Screening through Molecular Docking, Negative Image-Based Screening, Machine Learning and Molecular Dynamics Simulation Studies
Md Ataul Islam, Dawood B. Dudekula, V.P. Subramanyam Rallabandi, Sridhar Srinivasan, Sathishkumar Natarajan, Hoyong Chung, Junhyung Park
SJR Q1International Journal of Molecular SciencesOA

Cytochrome P450 3A5 (CYP3A5) is one of the crucial CYP family members and has already proven to be an important drug target for cardiovascular diseases. In the current study, the PubChem database was screened through molecular docking and high-affinity molecules were adopted for further assessment. A negative image-based (NIB) model was used for a similarity search by considering the complementary shape and electrostatics of the target and small molecules. Further, the molecules were segregated

Computational Theory and MathematicsComputer Science
12
Article|11 citations·2022
Elevated CO2 Alters the Physiological and Transcriptome Responses of Pinus densiflora to Long-Term CO2 Exposure
Tae‐Lim Kim, Hyemin Lim, Hoyong Chung, Karpagam Veerappan, Chang‐Young Oh
SJR Q1PlantsOA

Physiological response and transcriptome changes were observed to investigate the effects on the growth, metabolism and genetic changes of Pinus densiflora grown for a long time in an environment with an elevated atmospheric CO2 concentration. Pine trees were grown at ambient (400 ppm) and elevated (560 ppm and 720 ppm) CO2 concentrations for 10 years in open-top chambers. The content of nonstructural carbohydrates was significantly increased in elevated CO2. It was notable that the contents of

Plant ScienceAgricultural and Biological Sciences
13
Article|10 citations·2021
Physiological and Transcriptome Responses to Elevated CO2 Concentration in Populus
Tae‐Lim Kim, Hoyong Chung, Karpagam Veerappan, Wi Young Lee, Danbe Park, Hyemin Lim
SJR Q1ForestsOA

Global climate change is heavily affected by an increase in CO2. As one of several efforts to cope with this, research on poplar, a representative, fast growing, and model organism in plants, is actively underway. The effects of elevated atmospheric CO2 on the metabolism, growth, and transcriptome of poplar were investigated to predict productivity in an environment where CO2 concentrations are increasing. Poplar trees were grown at ambient (400 ppm) or elevated CO2 concentrations (1.4× ambient,

Plant ScienceAgricultural and Biological Sciences
14
Article|8 citations·2022
Developmental Transcriptome Analysis of Red-Spotted Apollo Butterfly, Parnassius bremeri
Kang-Woon Lee, Michael Immanuel Jesse Denison, Karpagam Veerappan, Sridhar Srinivasan, Bohyeon Park, Sathishkumar Natarajan, Hoyong Chung, Junhyung Park
SJR Q1International Journal of Molecular SciencesOA

Parnassius bremeri (P. bremeri), a member of the genus Snow Apollo in the swallowtail family (Papilionidae), is a high alpine butterfly that lives in Russia, Korea, and China. It is an endangered wildlife (Class I) in South Korea and is a globally endangered species. The lack of transcriptomic and genomic resources of P. bremeri significantly hinders the study of its population genetics and conservation. The detailed information of the developmental stage-specific gene expression patterns of P.

GeneticsBiochemistry, Genetics and Molecular Biology
15
Article|8 citations·2020
Deciphering Novel Antimicrobial Peptides from the Transcriptome of Papilio xuthus
Joon Ha Lee, Hoyong Chung, Yong Pyo Shin, Mi‐Ae Kim, Sathishkumar Natarajan, Karpagam Veerappan, Seong Hyun Kim, Junhyung Park, Jae Sam Hwang
SJR Q1InsectsOA

An insect’s innate immune system is the front line of defense against many invading microorganisms. One of the important components of this defense system is antimicrobial peptides (AMPs). Papiliocin is a well-studied antimicrobial peptide (AMP) isolated from the swallowtail butterfly, Papilio xuthus, and it was previously reported to be effective against Gram-positive bacteria, Gram-negative bacteria, and fungi, particularly in drug resistant Gram-negative bacteria. Hence, we aimed to identify

MicrobiologyImmunology and Microbiology

Research Areas

Molecular BiologyPlant ScienceBiotechnologyMicrobiologyComputational Theory and MathematicsDermatology

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