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Hwajung Yoo

Korea University · 医学

研究室紹介

Professor Hwajung Yoo's research lab specializes in dermatological interventions using advanced energy-based technologies, focusing on the development and evaluation of non-invasive and minimally invasive treatments for skin conditions. The lab investigates microwave and light-based therapies—such as short-pulsed intense pulsed light and laser systems—for inflammatory and vascular disorders like rosacea and axillary hyperhidrosis. It also explores the immunological mechanisms underlying chronic skin diseases, including atopic dermatitis and the role of cytokines such as IL-33 and TSLP. Additionally, the lab examines the safety and efficacy of injectable biodegradable polymers, like poly(L-lactic acid), in skin rejuvenation and regenerative dermatology.

microwave therapylight-based therapyskin rejuvenationinflammatory skin diseasedermal injectables

Research Overview

Papers
182
Total Citations
1,620
Papers (5y)
35
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
35total
2022
2023
2024
2025
2026
Citations per year (5y)
125total
20222023202420252026

Selected Papers

15
1
Article|67 citations·2016
Dermal Remodeling of Burn Scar by Fractional CO2 Laser
Sang-jun Lee, Dong-Hye Suh, Jimin Lee, Kye-Yong Song, Hwa Jung Ryu
SJR Q1Aesthetic Plastic Surgery
DermatologyMedicine
2
Article|52 citations·2013
The efficacy of a microwave device for treating axillary hyperhidrosis and osmidrosis in Asians: a preliminary study
Sang‐Jun Lee, Ka-Yeun Chang, Dong-Hye Suh, Kye-Yong Song, Hwa Jung Ryu
SJR Q2Journal of Cosmetic and Laser Therapy

A microwave-based device has been developed to treat axillary hyperhidrosis by selectively heating the interface between the skin and underlying fat in the axilla. This study was conducted to evaluate the efficacy and safety of microwave-based devices for axillary hyperhidrosis and osmidrosis in Asians. Eleven patients (8 females and 3 males, age range 20-52 years, mean age 37.6 years) with axillary hyperhidrosis or osmidrosis were enrolled, treated with the microwave-based device, and followed

PhysiologyMedicine
3
Article|46 citations·2005
Iatrogenic Mycobacterium abscessus infection associated with acupuncture: clinical manifestations and its treatment
Hwa Jung Ryu, Woo Joo Kim, Chil Hwan Oh, Hae Jun Song
SJR Q1International Journal of Dermatology

BACKGROUND: Mycobacterial infections transmitted by acupuncture are an emerging problem. There have been two reports of mycobacterial infections complicating acupuncture in the English literature. AIM: To describe the clinical manifestations and treatment of patients who acquired localized Mycobacterium abscessus infection in the process of acupuncture. METHODS: Clinical manifestations and responses to different methods of treatment were reviewed in 40 patients who developed various skin lesions

EpidemiologyMedicine
4
Article|46 citations·2015
IL‐33 induces Egr‐1‐dependent TSLP expression via the MAPK pathways in human keratinocytes
Woo‐In Ryu, Hana Lee, Jin Hee Kim, Hyun Cheol Bae, Hwa Jung Ryu, Sang Wook Son
SJR Q1Experimental Dermatology

Atopic dermatitis (AD) is a chronic inflammatory skin disease in which T-helper type 2 (Th2)-type immune responses are dominant. Th2 cytokine, interleukin (IL)-33 and thymic stromal lymphopoietin (TSLP) have been suggested to have an important role in AD. IL-33 is highly expressed in AD, but its role in AD has not yet been fully understood. To further identify the role of IL-33 in AD, we investigated the expression of TSLP induced by IL-33 in keratinocytes. This study revealed that IL-33 induced

ImmunologyImmunology and Microbiology
5
Article|35 citations·2018
Comparative efficacy of short-pulsed intense pulsed light and pulsed dye laser to treat rosacea
Bo Young Kim, Hye-Rim Moon, Hwa Jung Ryu
SJR Q2Journal of Cosmetic and Laser Therapy

<b>Background</b>: Laser and light-based therapies have often been used successfully to treat rosacea. Recently, short-pulsed intense pulsed light (IPL) that emitted pulse durations down to 0.5 ms was found to be effective for rosacea treatment. <b>Objective</b>: This study evaluated the efficacy of short-pulsed IPL in the treatment of rosacea compared with pulsed dye laser (PDL) using same pulse duration and fluence. <b>Materials and Methods</b>: Nine patients with rosacea were enrolled in a ra

DermatologyMedicine
6
Article|34 citations·2020
Parkinson’s disease and skin cancer risk: a nationwide population‐based cohort study in Korea
Hwa Jung Ryu, Joo‐Hyun Park, Moon Ki Choi, Jong Hyun Jung, K. Han, Dong‐Yeul Kwon, Do‐Hoon Kim, Young‐Gyu Park
SJR Q1Journal of the European Academy of Dermatology and Venereology

BACKGROUND: Previous studies have reported that patients with Parkinson's disease (PD) have a significantly lower risk of cancer. Studies reporting prevalence of skin cancers in Parkinson's disease mostly involve Caucasians. OBJECTIVE: A nationwide population-based study was conducted to determine the risk of skin cancer in patients diagnosed with PD in Korea. METHODS: Data obtained from National Health Insurance Claims records were used to retrieve information about 70 780 patients with newly d

NeurologyMedicine
7
letter|33 citations·2016
IL-33 down-regulates filaggrin expression by inducing STAT3 and ERK phosphorylation in human keratinocytes
Woo‐In Ryu, Hana Lee, Hyun Cheol Bae, Hwa Jung Ryu, Sang Wook Son
SJR Q1Journal of Dermatological Science
DermatologyMedicine
8
Article|33 citations·2023
Skin rejuvenation effect of the combined PDLLA and non cross‐linked hyaluronic acid: A preliminary study
Suk Bae Seo, Hyun‐Woo Park, Ju Young Jo, Hwa Jung Ryu
SJR Q2Journal of Cosmetic DermatologyOA

BACKGROUND: Skin aging is characterized by wrinkles, rough skin texture, pigmentation, facial erythema, and telangiectasia through structural and functional changes in the epidermis and dermis. Recently, injectable poly(D, L-lactic acid), a biodegradable polymer, has been used widely for skin rejuvenation. AIMS: This study aims to assess the efficacy and safety of injectable dermal poly D, L-lactic acid) for skin rejuvenation. PATIENTS/METHODS: A total of 16 patients who desired skin rejuvenatio

DermatologyMedicine
9
Article|33 citations·2019
The efficacy of powdered polydioxanone in terms of collagen production compared with poly‐L‐lactic acid in a murine model
Chang Min Kim, Bo Young Kim, Dong Hye Suh, Sang Jun Lee, Hye Rim Moon, Hwa Jung Ryu
SJR Q2Journal of Cosmetic Dermatology

BACKGROUND: There are many collagen-stimulating fillers, including calcium hydroxyapatite, polycaprolactone (PCL), and poly-L-lactic acid (PLLA), and other materials have been tested. Polydioxanone (PDO) has recently been used as absorbable thread-lifting material due to its collagen-forming effects. PDO in powdered form is expected to be a good material for collagen-producing fillers. OBJECTIVES: To evaluate the collagen-producing effects of powdered PDO injection compared with PLLA injection i

DermatologyMedicine
10
Article|28 citations·2018
Comparative effects of various absorbable threads in a rat model
Jung Jin Shin, Tae Jun Park, Bo Young Kim, Chang Min Kim, Dong Hye Suh, Sang Jun Lee, Hye-Rim Moon, Hwa Jung Ryu
SJR Q2Journal of Cosmetic and Laser Therapy

We were able to observe more collagen production in multiple stranded PDO threads compared to a single strand and that increasing number of threads leads to more collagen synthesis.

DermatologyMedicine
11
Article|28 citations·2015
Intense focused ultrasound for facial tightening: Histologic changes in 11 Patients
Dong Hye Suh, Byoung Joon So, Sang Jun Lee, Kye-Yong Song, Hwa Jung Ryu
SJR Q2Journal of Cosmetic and Laser Therapy

Intense focused ultrasound can be used as a non-invasive skin tightening technique in Asian patients. It induced collagen generation in the dermis and fat layers and was effective and safe in our study population.

DermatologyMedicine
12
Article|27 citations·2017
Cryolipolysis for submental fat reduction in Asians
Dong Hye Suh, Ji Hyun Park, Hae Kyoung Jung, Sang Jun Lee, Hyun Joo Kim, Hwa Jung Ryu
SJR Q2Journal of Cosmetic and Laser Therapy

The results of this study indicate that submental fat can be safely and effectively reduced with use of a cryolipolysis applicator. The present study shows that cryolipolysis can be an option for nonsurgical facial contouring.

SurgeryMedicine
13
Article|26 citations·2016
Non-invasive cryolipolysis to reduce subcutaneous fat in the arms
Sang Jun Lee, Hee Won Jang, Hyun‐Joo Kim, Dong Hye Suh, Hwa Jung Ryu
SJR Q2Journal of Cosmetic and Laser Therapy

One treatment using a flat vacuum cryolipolysis applicator was safe and effective to reduce arm fat.

SurgeryMedicine
14
Article|26 citations·2021
Photothermal therapy using gold nanoparticles for acne in Asian patients: A preliminary study
Dong Hye Suh, Tae Jun Park, Jae Yeong Jeong, Ko Eun Kim, Jong Heon Park, Sang Jun Lee, Hyun Joo Kim, Hwa Jung Ryu
SJR Q1Dermatologic Therapy

Acne is a common skin disease that occurs in pilosebaceous units and is often prevalent in adolescence. There are many acne treatments, but they are associated with side effects, such as antibiotic resistance, teratogenicity, and irritation. Therefore, it is necessary to develop a more effective and safe alternative treatment for managing acne in patients of all ages. This study aimed to confirm the effect of gold photothermal therapy for acne. About 12 patients who visited the dermatologic clin

DermatologyMedicine
15
Article|22 citations·2014
Clinical effectiveness of non-invasive selective cryolipolysis
Jiehoon Kim, Dai Hyun Kim, Hwa Jung Ryu
SJR Q2Journal of Cosmetic and Laser Therapy

Non-invasive selective cryolipolysis has been reported to be a safe and effective treatment modality for the reduction of excess adipose tissue. Therefore, cryolipolysis is a promising technology that could be an appropriate and safe therapeutic option for subcutaneous fat reduction.

SurgeryMedicine

Research Areas

DermatologyEpidemiologySurgeryCell BiologyPathology and Forensic MedicineOncology

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