Hyeong Kyu Kwak
Seoul National University · 医学
研究室紹介
Professor Hyeong Kyu Kwak's research lab specializes in critical care medicine, with a primary focus on improving outcomes in patients following cardiac arrest and sepsis. The lab investigates prognostic factors, hemodynamic and neurological monitoring, and the impact of temperature management strategies such as targeted temperature management (TTM) in critically ill patients. Key research directions include the correlation between noninvasive and invasive brain temperature monitoring, early detection of sepsis—particularly in afebrile patients—and optimizing treatment timing to reduce mortality. The lab integrates clinical data from multicenter registries and animal models to inform evidence-based critical care practices.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
5Regardless of target temperatures, low rSO<sub>2</sub> levels during TTM were significantly associated with poor 6-month neurological outcomes in OHCA survivors.
Afebrile sepsis patients were associated with higher 28-day mortality compared to their febrile counterparts and were delayed in receiving antibiotics. This underscores the need for improved early detection and treatment strategies for the afebrile sepsis patients.
Objective: To identify prognostic factors for the 28-day mortality of septic patients who received timely antibiotics and fluid resuscitation in accordance with the Surviving Sepsis Campaign guidelines. Methods: This research was a subgroup analysis of a multicenter observational study using data from a sepsis registry. Adult patients were included if they received intravenous antibiotics within 2 hours of emergency department arrival and any volume of fluid resuscitation. Sepsis was defined acc
We aimed to evaluate correlation and agreement between noninvasive brain temperature (T BN ) and invasive brain temperature (T BI ) measurement during targeted temperature management (TTM) in a swine cardiac arrest model. Defibrillation attempts were provided after 5 minutes of ventricular fibrillation and 12 minutes of cardiopulmonary resuscitation in five pigs. After return of spontaneous circulation, TTM was provided with induction and maintenance phases with a target temperature of 33°C for
Research Areas
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