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Hyun-Joon Jang

Yonsei University · 医学

研究室紹介

Professor Hyun-Joon Jang's research lab specializes in spinal surgery and deformity, with a strong focus on improving surgical outcomes through advanced imaging, biomechanical analysis, and personalized risk prediction. The lab investigates critical complications such as implant subsidence, proximal junctional kyphosis (PJK), and mechanical failures after spinal fusion, particularly in adult spinal deformity and degenerative conditions. A key direction involves developing patient-specific predictive models—such as risk calculators for PJK and evaluation of anatomical parameters like the K-line and T1 slope—to guide precision spinal surgery. The lab also explores the impact of frailty and short-term prognosis in elderly patients, emphasizing individualized decision-making in high-risk populations.

spinal deformityproximal junctional kyphosissurgical risk predictioncervical myelopathyspine surgery outcomes

Research Overview

Papers
39
Total Citations
247
Papers (5y)
29
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
29total
2022
2023
2024
2025
2026
Citations per year (5y)
71total
20222023202420252026

Selected Papers

15
1
Article|84 citations·1997
The incidence of the factor V Leiden mutation in an obstetric population and its relationship to deep vein thrombosis
Donna Dizon‐Townson, Lesa Nelson, Hyun Jun Jang, Michael W. Varner, Kenneth Ward
SJR Q1American Journal of Obstetrics and Gynecology
HematologyMedicine
2
Article|25 citations·2020
Does Graft Position Affect Subsidence After Anterior Cervical Discectomy and Fusion?
Hyun Jun Jang, Dong Kyu Chin, Kyung Hyun Kim, Jeong Yoon Park
SJR Q1Global Spine JournalOA

STUDY DESIGN: Retrospective cohort study. OBJECTIVE: Implant subsidence is an important prognostic factor after anterior cervical discectomy and fusion (ACDF). Our purpose in this study was to investigate whether graft position affects subsidence after ACDF and to determine if there is a difference in clinical results based on allograft subsidence and position. METHODS: We reviewed 92 patients who underwent single-level ACDF with allograft and plate between January 2012 and October 2018. Treatme

SurgeryMedicine
3
Article|15 citations·2023
Development and Validation of an Online Calculator to Predict Proximal Junctional Kyphosis After Adult Spinal Deformity Surgery Using Machine Learning
Chang-Hyun Lee, Dae Jean Jo, Jae Keun Oh, Seung-Jae Hyun, Jin Hoon Park, Kyung Hyun Kim, Junseok Bae, Bong Ju Moon, Chang Kyu Lee, Myoung Hoon Shin, Hyun Jun Jang, Moon-Soo Han
SJR Q1NeurospineOA

OBJECTIVE: Although adult spinal deformity (ASD) surgery aims to restore and maintain alignment, proximal junctional kyphosis (PJK) may occur. While existing scoring systems predict PJK, they predominantly offer a generalized 3-tier risk classification, limiting their utility for nuanced treatment decisions. This study seeks to establish a personalized risk calculator for PJK, aiming to enhance treatment planning precision. METHODS: Patient data for ASD were sourced from the Korean spinal deform

SurgeryMedicine
4
Article|15 citations·2021
Influence of Frailty on Life Expectancy in Octogenarians After Lumbar Spine Surgery
Hyun Jun Jang, Dong Kyu Chin, Jeong Yoon Park, Sung Uk Kuh, Keun Su Kim, Yong Eun Cho, Kyung Hyun Kim
SJR Q1NeurospineOA

There was no relationship in long-term survival according to frailty in patients 80 years of age or older, but a difference was identified in short-term mortality. When making a surgical decision for lumbar spine surgery in frail patients over 80 years of age, surgeons should pay attention to the short-term prognosis.

Geriatrics and GerontologyMedicine
5
Article|13 citations·2018
Simultaneous quantification of 18 saturated and unsaturated fatty acids and 7 sterols as their tert-butyldimethylsilyl derivatives in human saliva using gas chromatography-tandem mass spectrometry
Ju‐Yeon Moon, Tae Yeon Kong, Hyun Jun Jang, Han Chang Kang, Yong‐Yeon Cho, Joo Young Lee, Hye Suk Lee
SJR Q2Journal of Chromatography B
SurgeryMedicine
6
Article|13 citations·2021
Which Is More Predictive Value for Mechanical Complications: Fixed Thoracolumbar Alignment (T1 Pelvic Angle) Versus Dynamic Global Balance Parameter (Odontoid-Hip Axis Angle)
Kwang-Ryeol Kim, Jean‐Charles Le Huec, Hyun Jun Jang, Sung-Hyun Noh, Jeong Yoon Park, Yoon Ha, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Byung-Ho Jin, Yong Eun Cho, Kyung Hyun Kim
SJR Q1NeurospineOA

OBJECTIVE: In this study, we investigate about relationship between postoperative global sagittal imbalance and occurrence of mechanical complications after adult spinal deformity (ASD) surgery. In global sagittal balance parameters, odontoid-hip axis (OD-HA) angle and T1 pelvic angle (TPA) were analyzed. METHODS: Between January 2009 and December 2016, 199 consecutive patients (26 males and 173 females) with ASD underwent corrective fusion of more than 4 levels and were followed up for more tha

SurgeryMedicine
7
Article|12 citations·2025
The Role of K-Line and Canal-Occupying Ratio in Surgical Outcomes for Multilevel Cervical Ossification of the Posterior Longitudinal Ligament: A Retrospective Multicenter Study
Jun Jae Shin, Sun Joon Yoo, Dong Kyu Kim, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Won Joo Jeong
SJR Q1NeurospineOA

OBJECTIVE: To evaluate the impact of the K-line and canal-occupying ratio (COR) on surgical outcomes in patients with multilevel cervical ossification of the posterior longitudinal ligament (OPLL). METHODS: Patients with cervical myelopathy due to multilevel OPLL who underwent decompression surgery (anterior or posterior) from 2013 to 2022, with 2-year minimum follow-up, were enrolled. Radiological evaluations included K-line, COR, OPLL type/level, and cervical parameters (C2 slope [C2S], T1 slo

SurgeryMedicine
8
Article|12 citations·2014
Endovascular Treatment of Symptomatic High-Flow Vertebral Arteriovenous Fistula as a Complication after C1 Screw Insertion
Hyun Jun Jang, Se-yang Oh, Yu Shik Shim, Seung Hwan Yoon
SJR Q2Journal of Korean Neurosurgical SocietyOA

High-flow vertebral arteriovenous fistulas (VAVF) are rare complications of cervical spine surgery and characterized by iatrogenic direct-communication of the extracranial vertebral artery (VA) to the surrounding venous plexuses. The authors describe two patients with VAVF presenting with ischemic presentation after C1 pedicle screw insertion for a treatment of C2 fracture and nontraumatic atlatoaxial subluxation. The first patient presented with drowsy consciousness with blurred vision. The dif

SurgeryMedicine
9
Article|10 citations·2024
Re-Evaluating the Long-Term Efficacy of Semi-Rigid Fixation Using a Nitinol Spring Rod in Lumbar Surgery: A Retrospective Study on an Effective Alternative for Reducing Adjacent Segment Disease
Hyun Jun Jang, Bongju Moon, Dong Kyu Chin
SJR Q2Applied SciencesOA

Adjacent segment disease (ASD) is a prevalent complication following lumbar fusion surgery, representing a significant challenge in spinal surgery. This study aimed to assess the long-term outcomes of Nitinol spring rod semi-rigid fixation, a potential alternative to traditional rigid fixation, in reducing the incidence of ASD. This retrospective case study evaluated 89 patients who underwent lumbar or lumbosacral surgeries using a combination of Bioflex® (a Nitinol spring rod dynamic stabilizat

Pathology and Forensic MedicineMedicine
10
Article|10 citations·2024
Comparative Outcomes of Biportal Endoscopic Decompression, Conventional Subtotal Laminectomy, and Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar Central Stenosis
Mu Ha Lee, Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Dong Kyu Chin, Keun Su Kim, Jeong Yoon Park
SJR Q1NeurospineOA

OBJECTIVE: Spinal stenosis is a prevalent condition; however, the optimal surgical treatment for central lumbar stenosis remains controversial. This study compared the clinical outcomes and radiological parameters of 3 surgical. METHODS: unilateral laminectomy bilateral decompression with unilateral biportal endoscopy (ULBD-UBE), conventional subtotal laminectomy (STL), and minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF). METHODS: This retrospective study included 86 patient

Pathology and Forensic MedicineMedicine
11
Article|6 citations·2021
The Fate of Proximal Junctional Vertebral Fractures after Long-Segment Spinal Fixation : Are There Predictable Radiologic Characteristics for Revision surgery?
Hyun Jun Jang, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Bang Sang Hahn, Kyung Hyun Kim
SJR Q2Journal of Korean Neurosurgical SocietyOA

Proximal junctional vertebral compression fractures with greater early-stage decrement of adjacent disc height were associated with increased risk of future neurological deterioration and necessity of revision. The condition of adjacent disc degeneration should be considered regarding severity and revision rate of proximal junctional kyphosis/proximal junction failures.

SurgeryMedicine
12
Article|5 citations·2022
Clinical Effect of Transverse Process Hook with K-Means Clustering-Based Stratification of Computed Tomography Hounsfield Unit at Upper Instrumented Vertebra Level in Adult Spinal Deformity Patients
Jongwon Cho, Seungjun Ryu, Hyun Jun Jang, Jeong Yoon Park, Yoon Ha, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Kyung Hyun Kim
SJR Q2Journal of Korean Neurosurgical SocietyOA

OBJECTIVE: This study aimed to investigate the efficacy of transverse process (TP) hook system at the upper instrumented vertebra (UIV) for preventing screw pullout in adult spinal deformity surgery using the pedicle Hounsfield unit (HU) stratification based on K-means clustering. METHODS: We retrospectively reviewed 74 patients who underwent deformity correction surgery between 2011 and 2020 and were followed up for >12 months. Pre- and post-operative data were used to determine the incidence o

SurgeryMedicine
13
Article|3 citations·2022
Comparison of Whole Spine Sagittal Alignment in Patients with Spinal Disease between EOS Imaging System versus Conventional Whole Spine X-ray
Hyun Jun Jang, Jeong Yoon Park, Sung Uk Kuh, Yoon Ha, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Kyung Hyun Kim
SJR Q2Yonsei Medical JournalOA

EOS showed a negative SVA shift and lesser PT compared to WSX, especially in patients with sagittal imbalance. When preparing a surgical plan, surgeons should consider these differences between EOS and WSX.

SurgeryMedicine
14
Article|3 citations·2024
Prognostic Factors of Spinal Intramedullary Hemangioblastoma : Analysis of Surgical Outcomes and Tumor Characteristics
Hyun Jun Jang, Bong Ju Moon, Kyung Hyun Kim, Jeong Yoon Park, Dong Kyu Chin, Yong Eun Cho, Keun Su Kim
SJR Q2Journal of Korean Neurosurgical SocietyOA

OBJECTIVE: Spinal intramedullary hemangioblastoma is a rare and highly vascularized benign tumor. The characteristics of the tumor, its corresponding location, and surgical outcomes remain unknown. The purpose of this study was to identify risk factors and strategies for neurologic deterioration following hemangioblastoma surgery. METHODS: A comprehensive retrospective analysis was undertaken to evaluate patients who underwent surgical intervention for intramedullary hemangioblastoma at our inst

Cancer ResearchBiochemistry, Genetics and Molecular Biology
15
Article|3 citations·2023
Machine Learning-Based Pain Severity Classification of Lumbosacral Radiculopathy Using Infrared Thermal Imaging
Jinu Rim, Seungjun Ryu, Hyun Jun Jang, Hoyeol Zhang, Yong Eun Cho
SJR Q2Applied SciencesOA

Pain is subjective and varies among individuals. Doctors determine pain severity based on a patient’s self-reported symptoms. In such situations, a language barrier may prevent patients from expressing their pain accurately, which may cause doctors to underestimate their pain degree. Moreover, patients’ subjective descriptions of pain can determine their eligibility for secondary benefits, as in the case of compensation for traffic or industrial accidents. Therefore, to perform a multiclass pred

Radiology, Nuclear Medicine and ImagingMedicine

Research Areas

SurgeryPathology and Forensic MedicineNeurologyRadiology, Nuclear Medicine and ImagingMolecular BiologyHematology

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