Hyun-Kang Jeong
Korea University · 神経科学
研究室紹介
Professor Hyun-Kang Jeong's research lab specializes in neuropsychiatry and clinical neuroscience, focusing on the neurophysiological and clinical aspects of mood and cognitive disorders in older adults and patients with schizophrenia or dementia. The lab investigates non-pharmacological interventions such as cognitive stimulation, the role of neuroimaging and EEG in distinguishing psychiatric diagnoses like adjustment disorder and major depressive disorder, and the impact of psychotropic medications—including long-acting injectables and ECT—on brain function and treatment outcomes. A key emphasis is placed on improving mental health care through personalized, evidence-based approaches in aging populations and severe mental illness.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15Objective: Although cognitive stimulation (CS) is one of the most popular non-pharmacological interventions for people with dementia, its efficacy is still debatable. We performed a meta-analysis of randomized controlled trials (RCTs) on the efficacy of CS in people with dementia. Methods: Data sources were identified by searching PubMed, MEDLINE, Embase, psychINFO, and Cochrane Reviews Library. A total of 7,354 articles were identified, and of these, 30 RCTs were selected based on the selection
Antipsychotic medications are important for the successful management of schizophrenia. Continuous treatment with medication is superior in relapse prevention and non-adherence to antipsychotic medication is associated with a poor clinical outcome. Long-acting injectable antipsychotics (LAIs) that can guarantee adherence to a treatment regimen could be a useful treatment option. With the introduction of second-generation atypical antipsychotics-long acting injection (SGA-LAI), the risks for extr
ObjectiveaaA community survey was performed to investigate the factors and perspectives associated with happiness among the elderly in Korea (≥60 years). MethodsaaEight hundred volunteers selected from participants in the Ansan Geriatric study (AGE study) were enrolled, and 706 completed the survey. The Happiness Questionnaire (HQ), which asks four questions about happiness, was administered. To explore the relationship between happiness and depression, the Geriatric Depression Scale (GDS) and t
Objective Adjustment disorder (ADJ) is a common diagnosis. However, it is difficult to distinguish ADJ from other major Axis I disorders, such as major depressive disorder (MDD). The aim of this study was to determine the distinguishing neurophysiological characteristics between ADJ and MDD using quantitative analysis of an electroencephalogram (QEEG). Methods The study included 30 patients with ADJ and 51 patients with MDD. Resting (eye closed) vigilance controlled EEG recordings were assessed
ObjectiveaaComorbid depression is common in patients with Alzheimer’s disease (AD). An increase in white matter lesions (WMLs) has been associated with depression in both elderly individuals with normal cognition and patients with Alzheimer’s disease. We investigated whether the severity and location of WMLs influence the association between WMLs and comorbid depression in AD. MethodsaaWe enrolled 93 AD patients from Seoul National University Bundang Hospital. We administered both the Mini Inter
Objectives: To analyze the relationship between seizure threshold (ST) and psychotropic drugs in patients treated with ECT. Methods: We examined clinical data from 43 patients. ST was titrated at each treatment session. We examined associations between ST and psychotropic drugs using multivariate correlation analyses. Data are presented as initial ST, the difference in ST between the first and 10th sessions (ΔST10th), and the mean difference in ST between the first and last sessions (mean ΔSTlas
Objectives: The purpose of the study was to examine the cost of illness and quality of life (QOL) of patients and caregivers with mild cognitive impairment (MCI) or Alzheimer’s disease (AD) based on their severity and to identify factors affecting the QOL of the patients and their caregivers. Methods: The subjects of this study were 140 patients with MCI or AD and 121 caregivers for those patients. The cost of illness was investigated as direct costs (medical and nonmedical costs) and indirect c
Objectives: Although many studies on seasonal variations in mood and behavior have been carried out in foreign countries, no such study has previously been undertaken in Korea. The goal of this study was to estimate the frequency of seasonal variations in mood and behavior among Korean medical students. Methods: 297 medical students from Korea University College of Medicine participated in this study. The subjects were surveyed with a Korean translation of the Seasonal Pattern Assessment Questio
연구목적 집단 치료 방법 중의 하나인 소시오드라마가 종합병원의료종사자의 직무 만족도와 소진정도를 개선할 수 있는지와 직종 및 직종 내의 갈등, 직무만족도, 그리고 소진정도의 관계를 알아보고자 본 연구를 수행하였다. 방 법 종합병원에 근무하는 간호사 20명에게 정신과 전문의가 소시오드라마에 참여를 권유하여 동의한 15명을 대상으로 하였다. 소시오드라마 시행 1주후 병동조직특성척도(ward organizational feature scale)과 소진척도(Maslach burnout inventory)를 작성하게 하였다. 대조군으로는 소시오드라마 시행군과 동일병동에 근무하는 간호사들 중 소시오드라마에 참여하지 않았던 20명에게 동일한 척도를 시행하기를 권유하였으며 17 명이 척도를 완성하였다. 결 과 소시오드라마 시행군(N=15)은 대조군(N=17)에 비해 소진정도가 유의하게 낮았다. 간호사/의사관계와 직무만족도 및 소진정도와 유의한 상관관계를 보였으나 회귀분석을 통해 변인간 상
Dementia has became a major public health problem as the aged population is rapidly increasing. Dementia is underdiagnosed in primary care and many primary care physicians are hesitate to diagnose dementia. Early detection and starting appropriate treatment has been emphasized in managing dementia patients. The role of primary care physicians in caring for patients with demantia is important to efficiently manage dememtia and related socioeconomic burden since they meet first many patients mostl
Objectives : Schizophrenia is a chronic psychiatric disorder characterized by its debilitating course. It leads to personal and social dysfunctions, burdening patients and guardians heavily. Enhancing functional outcome is a major treatment goal, but pharmacotherapy alone is usually not enough. Hence, it is important to reveal clinical factors that can predict personal and social performance in schizophrenia patients. Analyze factors influencing personal and social performance in schizophrenia p
연구목적 여고생에서 월경전 증후군/월경전 불쾌장애의 빈도와 임상적 특징을 조사하고, 다양한 사회인구학적 요인과 월경 관련 요인이 월경전 증후군/월경전 불쾌장애에 미치는 영향을 분석한다. 방 법 서울시내에 위치한 5개 여자고등학교 학생 1,688명을 대상으로, 월경전 증상, 우울, 불안 척도 및 사회인구학적, 월경 관련 문항이 포함된 자기기입식 설문조사를 시행하였다. Premenstrual Symptom Screening Tool(PSST)를 기준으로 대상자를 3군으로 분류하여 월경전 증후군/월경전 불쾌장애의 빈도와 임상적 특징을 분석하였으며, 다변량 로지스틱 회귀분석을 시행하여 관련요인을 파악하였다. 결 과 Moderate to Severe PMS와 PMDD의 빈도는 각각 20.1%와 6.4%였다. 월경전 증상 중 과민성(78.8%), 피로감(76.4%), 감정기복(69.8%)의 빈도가 높았으며, 학업 수행(67.1%)영역에서 기능의 장애가 두드러졌다. 우울, 불안 수준을 보정한 분
연구 목적 일반 인구에서 스트레스, 우울 정도, 신체질환 간의 관계와 우울증의 위험 요인을 확인하고자 연구를 진행하였다. 방 법 2009년 1월부터 2009년 12월까지 고려대학교 구로병원 건강검진센터에 내원한 일반인 1,764명에서 인구역학 자료를 조사하고 PSS와 PHQ-9 설문지를 시행하였다. 스트레스군, 우울군, 신체질환군을 구분하여 스트레스, 우울, 신체질환 간의 상관분석과 로지스틱 회귀분석을 시행하였다. 결 과 1,476명의 연구 대상자 중 198명(11.8%)이 우울군에 해당되었으며, 평균 PSS 점수(23.19점)와 평균 PHQ-9 점수(12.95점) 모두 정상군에 비해 높았다. 스트레스가 높을수록, 신체질환이 많을수록 우울 점수도 증가하였다. 여성, 최근의 건강이상으로 내원한 사람, 불규칙적인 운동과 흡연력, 협심증과 뇌경색 기왕력이 있는 군에서는 우울증의 위험도가 증가하였다. 결 론 본 연구에서 PSS, PHQ-9은 건강검진센터에서 정신건강 선별검사를 시행할 수 있
연구목적임상현장에서 주로 환자나 간호사의 주관적인 수면보고에 의존하여 수면을 평가하고 있다. 본 연구에서는 주관적 수면평가와 활동기록을 이용한 수면평가를 비교하고자 한다. 방 법32명의 정신과 입원 환자를 대상으로 하였고, 대상자들에게 활동기록기를 이용한 수면평가, 수면일지, 주관적인 수면의 질에 대한 시각적 증상 정도 평가, BDI, STAI를 시행하였다. 간호사도 3일 동안 한 시간마다 환자의 수면을 평가하였다. 결 과환자의 보고와 활동기록기를 이용한 수면측정상 입면잠복시간에서 유의한 차이를 보였다. 환자는 간호사보다 자고 있음에도 깨어있었다고 더 많이 보고하였다. 주관적 수면평가와 활동기록 수면평가의 차이는 불안, 우울과 상관관계를 보였다. 결 론주관적으로 수면의 질을 낮게 평가하는 환자일수록 활동기록기로 측정한 입면잠복시간과 더 큰 차이를 보였고, 우울, 불안 증상이 심한 환자의 수면보고는 활동기록 측정값과 큰 차이를 보였다. 이런 환자들에게 수면의 질에 대한 질문만으로는 정
Objective: Cognitive dysfunction is frequently reported after surgery and anesthesia in elderly patients. This study aims to investigate the incidence of dementia for eight years after anesthesia. Methods: We extracted the data between 2007 and 2020 from the Health Insurance Review and Assessment Service Database. We analyzed risk of developing dementia after anesthesia using Cox proportional hazard models. Results: Data were collected from 62,541 patient. Among them, subjects with and without a
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