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Hyun Sun Jeon

Seoul National University · 医学

研究室紹介

Professor Hyun Sun Jeon's research lab specializes in anterior segment ophthalmology, with a primary focus on dry eye disease (DED) and cataract development in pediatric and systemic disease populations. The lab investigates objective diagnostic tools, including deep learning-based imaging systems for corneal staining and biometric devices for refractive surgery planning. Key research directions include the pathophysiology of meibomian gland dysfunction, novel therapeutic interventions such as diquafosol and cyclophosphamide, and the long-term ocular outcomes in patients with atopic dermatitis and autoimmune conditions.

dry eye diseasedeep learning imagingbiometric measurementcyclophosphamidecataract risk

Research Overview

Papers
96
Total Citations
698
Papers (5y)
32
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
32total
2022
2023
2024
2025
2026
Citations per year (5y)
132total
20222023202420252026

Selected Papers

15
1
Article|69 citations·2020
Comparison of Ocular Biometry and Refractive Outcomes Using IOL Master 500, IOL Master 700, and Lenstar LS900
Jae Shin Song, Do Yeh Yoon, Joon Young Hyon, Hyun Sun Jeon
SJR Q2Korean Journal of OphthalmologyOA

The IOL Master 700 and Lenstar LS900 demonstrated superior acquisition rates of biometric measurements compared with the IOL Master 500. Ocular biometry using the 3 different devices showed high agreement, although statistically significant differences were observed; however, since there was no difference in predicting the refractive outcomes, those differences are clinically negligible.

EpidemiologyMedicine
2
Article|37 citations·2021
Characteristics of dry eye patients with thick tear film lipid layers evaluated by a LipiView II interferometer
Yunjin Lee, Joon Young Hyon, Hyun Sun Jeon
SJR Q1Graefe s Archive for Clinical and Experimental OphthalmologyOA

PURPOSE: To investigate the characteristics of eyes with dry eye disease (DED) whose lipid layer thickness (LLT) measured 100 nm on a LipiView II interferometer and compare the DED parameters of them to those with LLT below 100 nm. METHODS: A total of 201 eyes of 102 enrolled DED patients (mean age 56.4 ± 11.8 years) were classified into 3 groups according to their average LLT; < 60 nm as thin-LLT (n = 49), 60-99 nm as normal-LLT (n = 77), and 100 nm as thick-LLT (n = 75). LLT, meiboscore, Schir

Public Health, Environmental and Occupational HealthMedicine
3
Article|25 citations·2017
Stereopsis and fusion in anisometropia according to the presence of amblyopia
Hyun Sun Jeon, Dong Gyu Choi
SJR Q1Graefe s Archive for Clinical and Experimental Ophthalmology
EpidemiologyMedicine
4
Article|20 citations·2016
The Efficacy of Diquafosol Ophthalmic Solution in Non-Sjögren and Sjögren Syndrome Dry Eye Patients Unresponsive to Artificial Tear
Hyun Sun Jeon, Joon Young Hyon
SJR Q2Journal of Ocular Pharmacology and Therapeutics

Three percent diquafosol tetrasodium treatment could be considered as an additive or substitute treatment when artificial tear treatment is insufficient, as it improved OSS and TBUT. This study also demonstrated that diquafosol treatment is beneficial for TBUT improvement in SS, while it is beneficial for OSS improvement in non-SS dry eye patients.

Public Health, Environmental and Occupational HealthMedicine
5
Article|16 citations·2024
Deep learning-based fully automated grading system for dry eye disease severity
Seong-Hwan Kim, Daseul Park, Youmin Shin, Mee Kum Kim, Hyun Sun Jeon, Young-Gon Kim, Chang Ho Yoon
SJR Q1PLoS ONEOA

There is an increasing need for an objective grading system to evaluate the severity of dry eye disease (DED). In this study, a fully automated deep learning-based system for the assessment of DED severity was developed. Corneal fluorescein staining (CFS) images of DED patients from one hospital for system development (n = 1400) and from another hospital for external validation (n = 94) were collected. Three experts graded the CFS images using NEI scale, and the median value was used as ground t

Public Health, Environmental and Occupational HealthMedicine
6
Article|16 citations·2015
Efficacy and safety of immunosuppressive agents in the treatment of necrotising scleritis: a retrospective, multicentre study in Korea
Hyun Sun Jeon, Joon Young Hyon, Mee Kum Kim, Tae-Young Chung, Kyung Chul Yoon, Jae Yong Kim, Kyung-Sun Na, Hyung Joon Kim, Tae‐im Kim, Jong Soo Lee, Hyung Keun Lee, Jong Suk Song
SJR Q1British Journal of OphthalmologyOA

The efficacy of cyclophosphamide in the treatment of necrotising scleritis was comparable with that of other ISAs. However, the rate of discontinuation due to side effects was much higher in the CYC group.

OphthalmologyMedicine
7
Article|15 citations·2018
Association of Pediatric Atopic Dermatitis and Cataract Development and Surgery
Hyun Sun Jeon, Mira Choi, Seong Jun Byun, Joon Young Hyon, Kyu Hyung Park, Sang Jun Park
SJR Q1JAMA OphthalmologyOA

Absolute risk of cataract was rare, with or without AD, even after 10 years of observation. However, our results suggest that pediatric patients with AD have an increased risk for cataracts requiring surgery and that disease severity may increase the risk for cataract development and cataract surgery.

DermatologyMedicine
8
Article|13 citations·2022
Clinical Characteristics and Therapeutic Outcomes of Pediatric Blepharokeratoconjunctivitis
Jayoon Moon, Junseok Lee, Mee Kum Kim, Joon Young Hyon, Hyun Sun Jeon, Joo Youn Oh
SJR Q1Cornea

PURPOSE: The purpose of this study was to determine the clinical characteristics, disease course, therapeutic outcomes, and prognostic factors for pediatric patients with blepharokeratoconjunctivitis (BKC). METHODS: A retrospective medical chart review was performed for patients aged 15 years or younger who had been diagnosed with BKC between 2004 and 2020 at 2 tertiary hospitals in Korea. The following data were collected: demographics, medical history, ocular findings, geometric profiling of c

OphthalmologyMedicine
9
Article|12 citations·2019
Effect of Donor Age on Graft Survival in Primary Penetrating Keratoplasty with Imported Donor Corneas
Hyeon Yoon Kwon, Joon Young Hyon, Hyun Sun Jeon
SJR Q2Korean Journal of OphthalmologyOA

Donor age may correlate with graft survival in primary PK performed with imported donor corneas. Donor age could be a considerable factor in primary PK with imported donor corneas, especially in preoperatively low-risk patients.

Radiology, Nuclear Medicine and ImagingMedicine
10
Article|12 citations·2016
Assessment of Transepidermal Water Loss From the Ocular Area in Dry Eye Disease
Hyun Sun Jeon, Sang Woong Youn, Hee Eun Jeon, Joo Hyun Kim, Joon Young Hyon
SJR Q1Investigative Ophthalmology & Visual ScienceOA

PURPOSE: To investigate transepidermal water loss (TEWL) from the ocular area in dry eye disease (DED) and evaluate the correlation between ocular TEWL and other DED parameters. METHODS: Transepidermal water loss from the ocular area in 56 eyes with DED and 38 healthy eyes was measured using a Tewameter TM300 that was equipped with custom made goggles (measuring temperature 24°C-26°C and relative humidity 35%-45%). The DED group was classified into two subgroups, aqueous deficient dry eye (ADDE)

Public Health, Environmental and Occupational HealthMedicine
11
letter|11 citations·2019
Conjunctival Pyogenic Granuloma: Cases with Undetermined Etiologies
Yunjin Lee, Joon Young Hyon, Hyun Sun Jeon
SJR Q2Korean Journal of OphthalmologyOA

Conjunctival Pyogenic Granuloma: Cases with Undetermined EtiologiesDear Editor, Conjunctival pyogenic granuloma (PG) is a benign vascular proliferation of immature capillaries that usually denotes sequelae of incomplete surgical or traumatic wound healing [1,2].It is most commonly seen at a traumatic wound site or near a suture line after surgery and other insults [3].Herein, we report three cases of conjunctival PG with unknown etiology in children and a young adult.Case 1.An 8-year-old boy pre

SurgeryMedicine
12
Article|10 citations·2018
Atopic dermatitis is not a risk factor for keratoconus: A population-based cohort study
Hyun Sun Jeon, Mira Choi, Seong Jun Byun, Leejee H. Suh, Joon Young Hyon, Kyu Hyung Park, Sang Jun Park
SJR Q1Journal of the American Academy of Dermatology
Immunology and AllergyMedicine
13
Article|9 citations·2017
Unilateral Posterior Polymorphous Corneal Dystrophy Presented as Anisometropic Astigmatism: 3 Case Reports
Hyun Sun Jeon, Joon Young Hyon
SJR Q3Case Reports in OphthalmologyOA

BACKGROUND: Posterior polymorphous corneal dystrophy (PPCD) is typically considered bilateral and asymptomatic. However, few case reports on patients with unilateral PPCD with asymmetric refractive error have mentioned anisometropic amblyopia development. In support of this, we report 3 cases of unilateral PPCD that presented as anisometropic astigmatism. Visual prognosis related to amblyopia development is discussed. CASE PRESENTATION: All 3 patients had a band lesion in the affected eye and a

Radiology, Nuclear Medicine and ImagingMedicine
14
Article|7 citations·2023
Accuracy of the PEARL-DGS Formula for Intraocular Lens Power Calculation in Post–Myopic Laser Refractive Corneal Surgery Eyes
Richul Oh, Joon Young Hyon, Hyun Sun Jeon
SJR Q1American Journal of Ophthalmology
Radiology, Nuclear Medicine and ImagingMedicine
15
Article|7 citations·2019
Contact Lens Induced Limbal Stem Cell Deficiency: Clinical Features in Korean Patients
Seung Chan Lee, Joon Young Hyon, Hyun Sun Jeon
SJR Q2Korean Journal of OphthalmologyOA

If a patient with a history of CL wear for an extended period of time presents with decreased visual acuity, practitioners should perform detailed examinations with suspicion of CL-LSCD, including fluorescein staining. CL-LSCD is usually reversible and close follow-up with conservative treatment is recommended as the initial treatment option.

Public Health, Environmental and Occupational HealthMedicine

Research Areas

Public Health, Environmental and Occupational HealthRadiology, Nuclear Medicine and ImagingOphthalmologyEpidemiologyLeadership and ManagementSurgery

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