Hyunchan Song

(1) Background: Although Candida albicans accounts for the majority of fungal infections, therapeutic options are limited and require alternative antifungal agents with new targets; (2) Methods: A biofilm formation assay with RPMI1640 medium was performed with Liriope muscari extract. A combination antifungal assay, dimorphic transition assay, and adhesion assay were performed under the biofilm formation condition to determine the anti-biofilm formation effect. qRT-PCR analysis was accomplished

The number of bees has decreased drastically partly due to bacterial pathogens like Paenibacillus larvae that cause American foulbrood disease. The recent emergence of pathogenic resistant strains makes it more difficult to, successfully, treat infections. Research on alternative antibacterial agents from naturally occurring plants that also have low toxicity levels is critical to address the issue of Paenibacillus larvae in bee colonies. Five compounds were screened with a minimal inhibitory co

Although honeybees (Apis mellifera) are crucial for maintenance of the ecosystem, population of honeybee has been steadily decreasing due to diseases including nosemosis. Nosemosis is a disease caused by Nosema ceranae and is now considered as a major threat to honeybees. N. ceranae is a microsporidian that stays in form of spore even before the infection, which makes it harder to control than other pathogens. People are now aware of this parasite, however, cure and preventive candidates for nos

Recently, number of honeybees (Apis mellifera) has visibly decreased because they are vulnerable to some diseases like American foulbrood disease. American foulbrood disease, which is caused by Paenibacillus larvae, is emerged as great cause of decrease in number of honeybees. After antibiotic-resistant strain emerged, it is now more difficult to treat those pathogens successfully. Researches on finding alternative antibacterial compound are ongoing. In this study, we examined the antibacterial

Honeybees (Apis mellifera) have been threatened by diseases and their numbers have been noticeably declining. Nosemosis, a disease caused by Nosema ceranae, is now a leading threat to honeybees. N. ceranae is a microsporidian that forms a spore before it infects the host, which makes it especially difficult to control compared to other pathogens. Because the awareness of nosemosis risk increased within decades, N. ceranae has been studied as a pathogen. Some studies showed the up/down-regulation

Nosemosis is a honeybee ( Apis mellifera) disease resulting from the intake of Nosema ceranae, which recently became a major threat to honeybees. N. ceranae is a microsporidian, which acts like a parasite and remains as a spore until the infection, resulting in high management difficulty. Until today, cure and preventative candidates are barely established. In this study, the preventive activity of Akebia quinata extract against nosemosis was done using Trichoplusia ni cell line, BTI-TN5B1-4, as

Nosemosis is a honeybee ( Apis mellifera) disease resulting from the intake of Nosema ceranae, which recently became a major threat to honeybees. N. ceranae is a microsporidian, which acts like a parasite and remains as a spore until the infection, resulting in high management difficulty. Until today, cure and preventative candidates are barely established. In this study, the preventive activity of Akebia quinata extract against nosemosis was done using Trichoplusia ni cell line, BTI-TN5B1-4, as

Nosema ceranae is a causative agent of nosemosis. It has been considered as a great threat to honeybees for some decade. We performed an experiment on antiparasitic activity of rutin using Trichoplusia ni cell line, BTI-TN5B1-4, which was used as a substitute for stable honeybee cell line. Without addition of any parasite, BTI-TN5B1-4 cells had consistent size with round shape. However, when spores of N. ceranae were treated on BTI-TN5B1-4, some cells exhibited its nosemosis with abnormally enla

Nosema ceranae is a causative agent of nosemosis. It has been considered as a great threat to honeybees for some decade. We performed an experiment on antiparasitic activity of rutin using Trichoplusia ni cell line, BTI-TN5B1-4, which was used as a substitute for stable honeybee cell line. Without addition of any parasite, BTI-TN5B1-4 cells had consistent size with round shape. However, when spores of N. ceranae were treated on BTI-TN5B1-4, some cells exhibited its nosemosis with abnormally enla

Introduction: The skin microbiota plays a crucial role in maintaining skin health and overall well-being. The composition of this microbial community is influenced by various host factors, including lifestyle habits, physiological parameters, and body composition. Methods: 1,053 participants were included in this study. The composition of the skin microbiota was determined by analysing facial skin microbiome collection, obtained after the consent of participants. Also, physical characteristics o

Background: Dermatophytes are a widespread fungal infection with growing concerns of antifungal resistance. Apple Cider Vinegar (ACV) is a traditional remedy known for its antimicrobial properties, but its efficacy against specific dermatophytes and its safety on host cells are not yet well-characterised. Methods: In this study, the in vitro antifungal activity of ACV was evaluated against six clinically relevant dermatophyte species by measuring the Minimum Inhibitory Concentration (MIC). The l