Hyung-beom Kim
Yonsei University
研究室紹介
Professor Hyung-beom Kim's research lab specializes in cutting-edge genome editing technologies, with a focus on developing and refining CRISPR-based tools for therapeutic applications. The lab explores innovative genome editors such as base editors and prime editors, aiming to correct pathogenic genetic variants with high precision and minimal off-target effects. Their work bridges molecular biology and translational medicine, targeting inherited and acquired genetic disorders with the goal of advancing gene therapy. The lab also investigates the mechanisms and applications of next-generation genome editing systems to enhance safety and efficacy in clinical settings.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
1Advances in sequencing technologies have facilitated the discovery of previously unknown genetic variants in both inherited andacquired disorders, and tools to correct these pathogenic variants are rapidly evolving. Since the first introduction of CRISPR-Cas9in 2012, the field of CRISPR-based genome editing has progressed immensely, giving hope to many patients suffering from geneticdisorders that lack effective treatment. In this review, we will examine the basic principles of CRISPR-based geno