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Hyung Gon Je

Seoul National University · 医学

研究室紹介

Professor Hyung Gon Je's research lab specializes in cardiovascular surgery and interventional cardiology, with a strong focus on minimally invasive surgical techniques for atrial fibrillation and structural heart disease. The lab investigates surgical ablation strategies—particularly off-pump and hybrid procedures—aimed at improving long-term outcomes and reducing complications. Additional research directions include the impact of psychological and socioeconomic factors on metabolic health, as well as infection prevention in critical care settings such as extracorporeal membrane oxygenation (ECMO). The lab integrates clinical outcomes research with patient-centered approaches to optimize surgical and interventional therapies.

minimally invasive surgeryatrial fibrillation ablationECMO infection preventionmetabolic syndromesurgical outcomes research

Research Overview

Papers
84
Total Citations
630
Papers (5y)
30
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
30total
2022
2023
2024
2025
2026
Citations per year (5y)
79total
20222023202420252026

Selected Papers

15
1
Review|111 citations·2015
A systematic review of minimally invasive surgical treatment for atrial fibrillation: a comparison of the Cox-Maze procedure, beating-heart epicardial ablation, and the hybrid procedure on safety and efficacy
Hyung Gon Je, Deborah J. Shuman, Niv Ad
SJR Q1European Journal of Cardio-Thoracic SurgeryOA

There is a growing trend to perform off-bypass surgical ablation for atrial fibrillation (AF) because it is perceived to be safer and more effective than the Cox-Maze procedure with cardiopulmonary bypass (CPB) support. In this systematic review, we compared three minimally invasive stand-alone surgical ablation procedures for AF: the endocardial Cox-Maze procedure, epicardial surgical ablation and a hybrid epicardial surgical and catheter-based endocardial ablation procedure (hybrid procedure).

Cardiology and Cardiovascular MedicineMedicine
2
Article|42 citations·2009
Comparison of radial artery patency according to proximal anastomosis site: Direct aorta to radial artery anastomosis is superior to radial artery composite grafting
Sung‐Ho Jung, Hyun Song, Suk Jung Choo, Hyung Gon Je, Cheol Hyun Chung, Joon‐Won Kang, Jae Won Lee
SJR Q1Journal of Thoracic and Cardiovascular SurgeryOA
SurgeryMedicine
3
Article|35 citations·2016
Gender-Specific Associations between Socioeconomic Status and Psychological Factors and Metabolic Syndrome in the Korean Population: Findings from the 2013 Korean National Health and Nutrition Examination Survey
Kyoung Im Cho, Bo Hyun Kim, Hyung Gon Je, Jae‐Sik Jang, Yong Hyun Park
SJR Q2BioMed Research InternationalOA

We aimed to assess the gender-specific associations between psychological factors and socioeconomic status (SES) and metabolic syndrome (MetS) in Korean adults. We examined 4,689 Korean adults aged 20-79 years who participated in the 2013 Korean National Health Examination and Nutrition Survey. With regard to SES, occupation status (none, manual, and nonmanual), marital status (single, married, divorced, and widowed), and psychological factors (detection of stress, depressive symptoms, and suici

HealthSocial Sciences
4
Article|32 citations·2011
Surgical results of active infective native mitral valve endocarditis: repair versus replacement
Sung‐Ho Jung, Hyung Gon Je, Suk Jung Choo, Hyun Song, Cheol Hyun Chung, Jae Won Lee
SJR Q1European Journal of Cardio-Thoracic Surgery

The present study showed that postoperative long-term survival and event-free survival in patients with active infective endocarditis of the native mitral valve were not statistically significantly different regardless of whether patients underwent MVP or MVR.

EpidemiologyMedicine
5
Article|27 citations·2020
Chlorhexidine bathing of the exposed circuits in extracorporeal membrane oxygenation: an uncontrolled before-and-after study
Hye Ju Yeo, Dohyung Kim, Mihyang Ha, Hyung Gon Je, Jeong-Soo Kim, Woo Hyun Cho
SJR Q1Critical CareOA

BACKGROUND: Although the prevention of extracorporeal membrane oxygenation (ECMO) catheter-related infection is crucial, scientific evidence regarding best practices are still lacking. METHODS: We conducted an uncontrolled before-and-after study to test whether the introduction of disinfection with 2% chlorhexidine gluconate (CHG) and 70% isopropyl alcohol (IPA) of the exposed circuits and hub in patients treated with ECMO would affect the rate of blood stream infection (BSI) and microbial colon

Biomedical EngineeringEngineering
6
Article|25 citations·2009
Right or left anterolateral minithoracotomy for repair of congenital ventricular septal defects in adult patients
Sung‐Ho Jung, Hyung Gon Je, Suk Jung Choo, Tae-Jin Yun, Cheol Hyun Chung, Jae Won Lee
SJR Q2Interactive Cardiovascular and Thoracic SurgeryOA

For most patients who present with ventricular septal defects (VSDs) in adulthood, the major concern is not the mortality or morbidity associated with repair surgery, but rather cosmetic problems arising from surgical scarring as a result of median sternotomy. From March 2005 to August 2008, nine patients (M:F=1:8) underwent repair of congenital VSD using right (n=7) or left (n=2) anterolateral minithoracotomy. We compared the perioperative data of these patients with that of the patients (n=8)

EpidemiologyMedicine
7
Article|25 citations·2009
Risk factors analysis on failure of maze procedure: mid-term results☆
Hyung Gon Je, Jae Won Lee, Sung Ho Jung, Suk Jung Choo, Hyun Song, Sung Cheol Yun, Cheol Hyun Chung
SJR Q1European Journal of Cardio-Thoracic SurgeryOA

OBJECTIVE: Since the late 1980s, surgical ablation of atrial fibrillation (AF) has been one of the most effective means of curing this arrhythmia. However, about 20% of patients who underwent maze procedures have shown recurrence of AF during the follow-up periods. The aim of this study is to evaluate our result of maze procedures in last decade and to analyze the risk factors of maze failure. METHODS: Between July 1997 and July 2007, 560 consecutive patients underwent maze procedures for AF by

Cardiology and Cardiovascular MedicineMedicine
8
Article|25 citations·2008
Impact of the Maze operation on the progression of mild functional tricuspid regurgitation
Hyung Gon Je, Hyun Song, Sung Ho Jung, Suk Jung Choo, Jong Min Song, Duk Hyun Kang, Sung Cheol Yun, Cheol Hyun Chung, Jae Kawn Song, Jae Won Lee
SJR Q1Journal of Thoracic and Cardiovascular SurgeryOA
Cardiology and Cardiovascular MedicineMedicine
9
Article|19 citations·2015
Correlation between Patient-Reported Symptoms and Ankle-Brachial Index after Revascularization for Peripheral Arterial Disease
Hyung Gon Je, Bo Hyun Kim, Kyoung Cho, Jae‐Sik Jang, Yong Bum Park, John A. Spertus
SJR Q1International Journal of Molecular SciencesOA

Improvement in quality of life (QoL) is a primary treatment goal for patients with peripheral arterial disease (PAD). The current study aimed to quantify improvement in the health status of PAD patients following peripheral revascularization using the peripheral artery questionnaire (PAQ) and ankle-brachial index (ABI), and to evaluate possible correlation between the two methods. The PAQ and ABI were assessed in 149 symptomatic PAD patients before, and three months after peripheral revasculariz

SurgeryMedicine
10
Article|18 citations·2021
A Risk Prediction Model for Operative Mortality after Heart Valve Surgery in a Korean Cohort
Ho Jin Kim, Joon Bum Kim, Seon‐Ok Kim, Sung‐Cheol Yun, Sak Lee, Cheong Lim, Jae Woong Choi, Ho Young Hwang, Kyung Hwan Kim, Seung Hyun Lee, Jae Suk Yoo, Kiick Sung
SJR Q3Journal of Chest SurgeryOA

This risk prediction model using a scoring system specific to heart valve surgery was developed from the KHVSR database. The risk prediction model showed that operative mortality could be predicted well in a Korean cohort.

Cardiology and Cardiovascular MedicineMedicine
11
Article|17 citations·2019
Effects of Preoperative Autologous Blood Donation in Patients Undergoing Minimally Invasive Cardiac Surgery
Mi‐Hee Lim, Hyung Gon Je, Min Ho Ju, J. Lee, Hye Rim Oh, Ye Ri Kim
The Korean Journal of Thoracic and Cardiovascular SurgeryOA

BACKGROUND: Preoperative autologous blood donation (PABD) is a conservation strategy for reducing allogenic blood transfusion (ABT) during minimally invasive cardiac surgery (MICS). We aimed to evaluate the effects of PABD on the frequency of ABT and clinical outcomes in patients undergoing MICS. METHODS: We enrolled 113 patients (47.8±13.1 years, 50 men) undergoing MICS without preoperative anemia (hemoglobin >11 g/dL) between 2014 and 2017. Of these patients, 69 (the PABD group) donated autolo

BiochemistryMedicine
12
Article|15 citations·2020
Early experience of pump-controlled retrograde trial off for weaning from veno-arterial extracorporeal membrane oxygenation in adult patients with cardiogenic shock
Min Ho Ju, Mi‐Hee Lim, Soo Yong Lee, Chee-Hoon Lee, Hyung Gon Je
SJR Q2Perfusion

INTRODUCTION: Pump-controlled retrograde trial off has recently been introduced as an effective method for weaning from veno-arterial extracorporeal membrane oxygenation in pediatric patients. However, studies on pump-controlled retrograde trial off in adults are still lacking. Thus, this study aimed to examine the outcomes of pump-controlled retrograde trial off for weaning from veno-arterial extracorporeal membrane oxygenation in adult patients. METHODS: Between January 2018 and July 2019, 87

Biomedical EngineeringEngineering
13
Article|13 citations·2008
Minimally Invasive Surgical Release of Entrapped Mapping Catheter in the Mitral Valve
Hyung Gon Je, Jeong Won Kim, Sung Ho Jung, Jae Won Lee
SJR Q1Circulation Journal

Two cases of catheter entrapment in the mitral valve, which is a rare complication of pulmonary vein isolation, were successfully treated via robot-assisted minimally invasive surgery.

Cardiology and Cardiovascular MedicineMedicine
14
Article|10 citations·2008
Brucella Endocarditis in a Non-Endemic Country First Reported Case in East Asia
Hyung Gon Je, Hyun Song
SJR Q1Circulation JournalOA

Human brucellosis is a rare zoonosis in East Asia. A case of brucella endocarditis in a 59-year-old farmer who had mild rheumatic mitral stenosis is presented. Excision of the mitral valve with associated vegetation was performed and a mechanical valve was substituted. Antibiotic treatment with doxycycline, rifampicin, and trimethoprim/sulfamethoxazole was continued for 6 months. After 18 months of follow-up, the patient had no symptoms and no signs of relapse.

Small AnimalsVeterinary
15
Article|9 citations·2021
Impact of Sarcopenia on Outcomes of Minimally Invasive Cardiac Surgery
Mi‐Hee Lim, Chee-Hoon Lee, Min Ho Ju, Hyung Gon Je
SJR Q1Seminars in Thoracic and Cardiovascular SurgeryOA

Sarcopenia is an objective marker of poor outcome following cardiac surgery through median sternotomy. However, the clinical impact of sarcopenia after minimally invasive cardiac surgery (MICS) has not been well established. This study aimed to analyze the influence of sarcopenia on the early and late outcomes following MICS. We retrospectively examined 1248 patients who underwent MICS via right mini-thoracotomy or upper sternotomy between February 2009 and April 2020. Patients older than 65 yea

PhysiologyMedicine

Research Areas

Cardiology and Cardiovascular MedicineSurgeryBiomedical EngineeringEpidemiologyBiochemistryHealth

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