Hyung Woo Jang

OBJECTIVES/HYPOTHESIS: To describe our tracheostomy procedure using a vertical skin incision and a horizontal intercartilaginous incision and to compare our postoperative results with those in the recent literature. STUDY DESIGN: Retrospective chart review and literature review. METHODS: One hundred eleven children underwent tracheostomy using a vertical skin incision and a horizontal intercartilaginous incision over a 9-year period. A retrospective chart review was undertaken with respect to th

The first aim of this study was to develop a prothrombin time international normalized ratio (PT INR) prediction model. The second aim was to develop a warfarin maintenance dose decision support system as a precise warfarin dosing platform. Data of 19,719 inpatients from three institutions was analyzed. The PT INR prediction algorithm included dense and recurrent neural networks, and was designed to predict the 5th-day PT INR from data of days 1-4. Data from patients in one hospital (n = 22,314)

The thoracic aorta dilated with aging and was larger in subjects with a larger body size. Sex differences in the gross aortic diameter might be related to differences in body size. The growth of the thoracic aorta was faster in younger subjects with a smaller indexed diameter.

Compared with TVr, TVR had acceptable early and late outcomes in patients with severe TR. TVR can be considered as a valid option with acceptable clinical outcomes in patients who are not suitable candidates for TVr.

Patients with untreated trivial or mild functional TR accompanied by mitral valve disease can develop significant TR during follow-up. TV ring annuloplasty can be performed without complications and can be beneficial for patients with trivial or mild functional TR who are undergoing MVR.

The objective of this study was to evaluate the effect of treatment with amino compounds and solvents in vivo on calcifications of glutaraldehyde (GA)-fixed pericardium. Groups of bovine pericardium samples were fixed with 0.5% GA. We used urazole and glutamate to neutralize the free aldehyde and some solvents (ethanol with octanol or octanediol) to reduce the phospholipid content in the bovine pericardial tissue. Tensile strength and thermal stability were evaluated before implantation. Twelve

BACKGROUND AND AIM OF THE STUDY: Mitral valve reconstruction (MVP) is currently the standard treatment for degenerative mitral regurgitation (MR). However, when MR is due to infective endocarditis (IE) the range of pathophysiology present often makes any repair challenging. Hence, the authors' clinical experience of MVP to treat MR caused by IE was analyzed. METHODS: Between September 2004 and March 2011, a total of 26 patients (20 males, six females) who had been diagnosed with MR due to IE (si

We sought to evaluate the outcomes of postoperative three-month dual antiplatelet therapy in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS) following off-pump coronary artery bypass grafting (OPCAB) with exclusively arterial grafts. Between 2013–2016, dual antiplatelet therapy (DAPT) with either aspirin + clopidogrel (ASA + CPD group, n = 100) or aspirin + ticagrelor (ASA + TCG group, n = 169) was prescribed postoperatively in 269 NSTE-ACS patients after total arterial OPCAB.

Reducing the cardiopulmonary bypass (CPB) priming volume in congenital cardiac surgery is important because it is associated with fewer transfusions. This retrospective study was designed to compare safety and transfusion volumes between the mini-volume priming (MP) and conventional priming (CP) methods. Between 2007 and 2012, congenital heart surgery using CPB was performed on 480 infants (≤5 kg): the MP method was used in 331 infants (MP group, 69.0%), and the CP method was used in 149 infants

Although Magna use led to decreased aortic valve pressure gradients at follow-up, overall and event-free survival rates were significantly better with use of the Perimount valve. Additional and larger studies are needed to confirm these results.

BACKGROUND AND AIM OF THE STUDY: The study aim was to investigate the correlation of myocardial fibrosis with myocardial remodeling and clinical outcome of aortic valve replacement (AVR) in patients with aortic stenosis and left ventricular (LV) hypertrophy. METHODS: Between 2007 and 2010, a total of 43 patients (23 males, 20 females; mean age 65.5 +/- 10.6 years; range: 33-84 years) underwent AVR at the authors' institution. During surgery, specimens (10 mm3) were obtained from the LV outflow t

− 148 − *서울대학교 의과대학 서울대학교병원 흉부외과학교실 Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine **서울대학교병원 임상의학 연구소, 바이오 이종장기개발사업단 Seoul National University Hospital Clinical Research Institute, Xenotransplantation Research Center †본 연구는 보건복지부 보건의료기술진흥사업의 지원에 의하여 이루어진 것임(과제고유번호: A040004-008). 논문접수일:2008년 10월 6일, 심사통과일:2009년 2월 3일 책임저자:김용진 (110-744) 서울시 종로구 연건동 28, 서울대학교어린이병원 흉부외과 (Tel) 02-2072-3638, (Fax) 02-745-1509, E-mail

Surgical AVR with AAR in AS patients with calcified ascending aortas led to acceptable early and late outcomes. Although the applications for TAVI are growing, a surgical approach may be an alternative option for relatively younger patients with severely calcified aorta.

배경: 심혈관 수술이 발달함에 따라 혈관 또는 판막 등의 일부로써 사용하기 위한 보철편의 필요성이 대두되고 있다. 저자들은 보철편의 기계적 성질을 객관적으로 평가하고 내구성에 대한 정보를 얻기 위하여 피로 자극 시험 장비를 개발하였고, 다양한 방법으로 처리된 우(牛)심낭편을 시험하여 그 결과를 확인하고 서로 비교하여 더 나은 처리방법을 찾고자 하였다. 대상 및 방법: 도살장에서 신선 우심낭편을 무균 채취한 뒤 총 16가지의 대표적인 처리방법으로 우심낭편을 고정 또는 탈세포화한 뒤 피로 실험 전후로 조직의 투과도와 유순도를 측정하여 비교하였고 또한 광학현미경을 통한 조직검사로 조직 구조의 가시적인 변화 정도를 확인하였다. 결과: 글루타르알데히드 단독으로 고정한 경우에 비해 글루타르알데히드와 용매를 혼합하여 고정한 경우가 더 좋은 기계적 내구성을 보였다. 최근 기성제품에서는 저농도 글루타르알데히드가 널리 쓰이고 있으나, 면역학적 이점이 있을 것으로 생각되는 고농도 글루타르알데히드로 고정