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Il Ki Hong

Kyung Hee University · 医学

研究室紹介

Professor Il Ki Hong's research lab specializes in nuclear medicine and molecular imaging, with a focus on the diagnostic and prognostic applications of PET/CT in oncology and musculoskeletal disorders. The lab investigates metabolic imaging biomarkers—particularly 18F-FDG uptake—for predicting outcomes in hepatocellular carcinoma and other cancers, aiming to guide personalized treatment strategies. Additional research interests include the use of advanced imaging techniques such as bone scintigraphy and 3'-deoxy-3'-[F]fluorothymidine PET in evaluating conditions like temporomandibular joint osteoarthritis and recurrent brain tumors. The lab emphasizes translational research that bridges clinical imaging with patient outcomes, especially in complex or atypical presentations such as syphilitic bone lesions or treatment-resistant cancers.

PET/CT imaging18F-FDG uptakehepatocellular carcinomamolecular imagingoncologic prognosis

Research Overview

Papers
70
Total Citations
863
Papers (5y)
10
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
10total
2021
2022
2023
2025
2026
Citations per year (5y)
55total
20212022202320252026

Selected Papers

15
1
Article|73 citations·2017
Preoperative prediction of microvascular invasion of hepatocellular carcinoma using 18F-FDG PET/CT: a multicenter retrospective cohort study
Seung Hyup Hyun, Jae Seon Eo, Bong‐Il Song, Jeong Won Lee, Sae Jung Na, Il Ki Hong, Jin Kyoung Oh, Yong An Chung, Tae Sung Kim, Mijin Yun
SJR Q1European Journal of Nuclear Medicine and Molecular ImagingOA
HepatologyMedicine
2
Review|71 citations·2014
Bone Involvement in Secondary Syphilis
Ki–Ho Park, Mi Suk Lee, Il Ki Hong, Ji‐Youn Sung, Sang‐Ho Choi, Sang Ok Park, Myung Jin Shin, Hye Won Chung, Sang Hoon Lee
SJR Q1Sexually Transmitted Diseases

Bone involvement is an unusual manifestation of secondary syphilis, but little information is available in the English-language literature. We carried out a systematic review of the English-language literature from 1964 to 2013, describing cases of secondary syphilis with bone involvement. We also describe a case of secondary syphilis with multiple osteolytic lesions, mimicking metastatic cancer or myeloma, which was included in an analysis of 37 eligible cases of secondary syphilis with bone in

PhysiologyMedicine
3
Article|48 citations·2016
18F-FDG PET/CT Can Predict Survival of Advanced Hepatocellular Carcinoma Patients: A Multicenter Retrospective Cohort Study
Sae Jung Na, Jin Kyoung Oh, Seung Hyup Hyun, Jeong Won Lee, Il Ki Hong, Bong‐Il Song, Tae Sung Kim, Jae Seon Eo, Sung Won Lee, Ie Ryung Yoo, Yong An Chung, Mijin Yun
SJR Q1Journal of Nuclear MedicineOA

Barcelona Clinic Liver Cancer (BCLC) stage C hepatocellular carcinoma (HCC) consists of a heterogeneous group of patients with a wide range of survival times, requiring further prognostic stratification to facilitate treatment allocation. We evaluated the prognostic value of <sup>18</sup>F-FDG uptake on PET/CT at the time of presentation in patients with BCLC stage C HCC. <b>Methods:</b> A total of 291 patients with BCLC stage C HCC who underwent <sup>18</sup>F-FDG PET/CT between 2009 and 2010 f

HepatologyMedicine
4
Article|48 citations·2012
Cortical Changes After Mental Imagery Training Combined With Electromyography-Triggered Electrical Stimulation in Patients With Chronic Stroke
Il Ki Hong, Jong Bae Choi, Jong Ha Lee
SJR Q1StrokeOA

BACKGROUND AND PURPOSE: Paresis of the upper extremity after stroke is not effectively solved by existing therapies. We investigated whether mental imagery training combined with electromyogram-triggered electric stimulation improved motor function of the paretic upper extremity in patients with chronic stroke and induced cortical changes. METHODS: Fourteen subjects with chronic stroke (≥12 months) were randomly allocated to receive mental imagery training combined with electromyogram-triggered

RehabilitationMedicine
5
Article|45 citations·2016
Prognostic Significance of18F-FDG Uptake in Hepatocellular Carcinoma Treated with Transarterial Chemoembolization or Concurrent Chemoradiotherapy: A Multicenter Retrospective Cohort Study
Jeong Won Lee, Jin Kyoung Oh, Yong An Chung, Sae Jung Na, Seung Hyup Hyun, Il Ki Hong, Jae Seon Eo, Bong‐Il Song, Tae Sung Kim, Do Young Kim, Seung Up Kim, Dae Hyuk Moon
SJR Q1Journal of Nuclear MedicineOA

(18)F-FDG uptake was an independent prognostic factor for PFS and OS in HCC patients treated with TACE or CCRT. Especially, in HCCs with high (18)F-FDG uptake, patients treated with CCRT showed better survival than those treated with TACE. (18)F-FDG PET/CT may help determine the treatment modality for intermediate-to-advanced-stage HCCs.

HepatologyMedicine
6
Article|37 citations·2016
Prognostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in patients with Barcelona Clinic Liver Cancer stages 0 and A hepatocellular carcinomas: a multicenter retrospective cohort study
Seung Hyup Hyun, Jae Seon Eo, Jeong Won Lee, Joon Young Choi, Kyung-Han Lee, Sae Jung Na, Il Ki Hong, Jin Kyoung Oh, Yong An Chung, Bong‐Il Song, Tae Sung Kim, Kyung Sik Kim
SJR Q1European Journal of Nuclear Medicine and Molecular ImagingOA
HepatologyMedicine
7
Article|23 citations·2019
Prediction of painful temporomandibular joint osteoarthritis in juvenile patients using bone scintigraphy
Yeon‐Hee Lee, Il Ki Hong, Yang‐Hyun Chun
SJR Q1Clinical and Experimental Dental ResearchOA

Abstract The study aims to evaluate whether bone scintigraphy is effective in diagnosing temporomandibular joint (TMJ) osteoarthritis (OA) in juvenile patients. A retrospective study was conducted with 356 consecutive patients with TMJ–OA who were clinically assessed according to the Research Diagnostic Criteria for Temporomandibular Disorders. Patients were assigned to three groups based on their ages: Group 1: aged 12–16 years; Group 2: aged 17–19 years; and Group 3: aged 20 years. Additionall

Complementary and Manual TherapyHealth Professions
8
Article|19 citations·2011
Diagnostic Usefulness of 3’-Deoxy-3’-[18F]Fluorothymidine Positron Emission Tomography in Recurrent Brain Tumor
Il Ki Hong, Jeong Hoon Kim, Young Ho Shin, Do Hoon Kwon, Seung Jun Oh, Jae Seung Kim
SJR Q3Journal of Computer Assisted Tomography

3'-Deoxy-3'-[F]fluorothymidine PET has a high sensitivity but a lower specificity, which has a limited role in the diagnosis of recurrent brain tumors as a complimentary tool of magnetic resonance imaging.

Radiology, Nuclear Medicine and ImagingMedicine
9
Article|19 citations·2020
<p>Diagnostic and Predictive Values of <sup>18</sup>F-FDG PET/CT Metabolic Parameters in <em>EGFR</em>-Mutated Advanced Lung Adenocarcinoma</p>
Il Ki Hong, Jeongmi Lee, In Kyoung Hwang, Seung Sook Paik, Chanwoo Kim, Seung Hyeun Lee
SJR Q2Cancer Management and ResearchOA

SUVmax may be predictive for <i>EGFR</i> mutational status, and MTV and TLG of primary tumors may be promising prognostic parameters; <sup>18</sup>F-FDG PET/CT has potential utility for the risk stratification of <i>EGFR</i>-mutated patients treated with targeted therapy.

Pulmonary and Respiratory MedicineMedicine
10
Article|12 citations·2011
Association of the Oncostatin M Receptor Gene Polymorphisms with Papillary Thyroid Cancer in the Korean Population
Il Ki Hong, Young‐Gyu Eun, Dae Han Chung, Kee Hwan Kwon, Deog Yoon Kim
SJR Q1Clinical and Experimental OtorhinolaryngologyOA

The results suggest that OSMR polymorphism rs2278329 is associated with clinicopathologic characteristics of the tumor growth and multifocality development.

OncologyMedicine
11
Article|9 citations·2011
Development of a Driving Simulator for Virtual Experience and Training of Drunk Driving
Il-Ki Hong, Jun-Beom Ryu, Jun-Hee Cho, Kohn-Ho Lee, Woon-Sung Lee
3rd International Conference on Road Safety and SimulationPurdue UniversityTransportation Research Board

The aim of this study is the development of a driving simulator for the virtual experience of drunk driving and education on its dangers. Towards this end, visual effects specially designed via a real-time image generation engine were implemented in the graphic database for distorted-vision generation, space perception ability impairment, and downscaled peripheral-vision scope. A steering wheel and brake model were tuned to simulate delay in the driver’s decision making, muscular control, and pe

Experimental and Cognitive PsychologyPsychology
12
Article|9 citations·2018
Prediction of vesicoureteral reflux in children with febrile urinary tract infection using relative uptake and cortical defect in DMSA scan
Il Ki Hong, Mi Hae Chung, Joong Hyun Bin, Kyung‐Yil Lee, Jung Sue Kim, Chung Ho Kim, Jin‐Soon Suh
SJR Q2Pediatrics & NeonatologyOA

Decreased relative function and increased extents of cortical defects on DMSA scan may be associated with the presence of VUR. These findings may assist pediatricians to decide whether febrile UTI children need to undergo VCUG.

Pediatrics, Perinatology and Child HealthMedicine
13
Article|8 citations·2010
A rare case of cerebral vasculitis in Henoch‐Schönlein purpura with emphasis on the diagnostic value of magnetic resonance angiography (MRA) and single‐photon emission computed tomography (SPECT) given normal magnetic resonance imaging (MRI)
Jin‐Soon Suh, Won‐Ho Hahn, B.C.J. Cho, Sung-Do Kim, Il Ki Hong
SJR Q1International Journal of Dermatology
Pulmonary and Respiratory MedicineMedicine
14
Article|7 citations·2011
F-18 FDG PET/CT of a Gastric Schwannoma
Il Ki Hong, Deog Yoon Kim
SJR Q2Nuclear Medicine and Molecular ImagingOA
GastroenterologyMedicine
15
Article|7 citations·2014
3'-Deoxy-3'-[18F]fluorothymidine positron emission tomography imaging of thymidine kinase 1 activity after 5-fluorouracil treatment in a mouse tumor model.
Il Ki Hong, Seog Young Kim, Jin Hwa Chung, Seung Jin Lee, Seung Jun Oh, Sang Ju Lee, Jungsu S. Oh, Jin‐Sook Ryu, Tae Won Kim, Deog Yoon Kim, Dae Hyuk Moon
PubMed

AIM: We aimed to investigate whether 3'-deoxy-3'-[(18)F]fluorothymidine ([(18)F]FLT) positron emission tomography (PET) can estimate thymidine kinase 1 (TK1) activity after thymidylate synthase (TS) inhibition by 5-fluorouracil (5-FU) in a mouse tumor model. MATERIALS AND METHODS: Nude mice with HT29 tumors were injected with phosphate-buffered saline or 5-FU (16.7 or 50 mg/kg). Twenty-four hours later, 2-hour dynamic images were acquired after injection of [(18)F]FLT. In another group of mice w

Radiology, Nuclear Medicine and ImagingMedicine

Research Areas

Pulmonary and Respiratory MedicineRadiology, Nuclear Medicine and ImagingNeurologyPhysiologyOncologyHepatology

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