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In Ong Han

Sungkyunkwan University · 医学

研究室紹介

Professor In Ong Han's research lab specializes in surgical oncology and pancreatic surgery, with a strong focus on improving outcomes in pancreatic and biliary tract malignancies. The lab investigates risk prediction models for postoperative complications—particularly postoperative pancreatic fistula (POPF)—using clinical data and artificial intelligence to enhance preoperative planning and patient stratification. Research also explores prognostic biomarkers such as ceruloplasmin in biliary tract cancer and the impact of perioperative fluid management on surgical outcomes. The lab integrates clinical data with advanced analytics to optimize surgical decision-making and patient care.

postoperative pancreatic fistularisk predictionpancreatic surgeryprognostic biomarkersartificial intelligence in surgery

Research Overview

Papers
267
Total Citations
2,561
Papers (5y)
119
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
119total
2022
2023
2024
2025
2026
Citations per year (5y)
520total
20222023202420252026

Selected Papers

15
1
Article|94 citations·2011
Early versus delayed laparoscopic cholecystectomy after percutaneous transhepatic gallbladder drainage
In Woong Han, Jin‐Young Jang, Mee Joo Kang, Kyoung Bun Lee, Seung Eun Lee, Sun‐Whe Kim
SJR Q1Journal of Hepato-Biliary-Pancreatic Sciences

BACKGROUND: Percutaneous transhepatic gallbladder drainage (PTGBD) is a procedure to resolve acute cholecystitis (AC). It may decrease the technical difficulty of laparoscopic cholecystectomy (LC) and thus may facilitate successful surgery when a patients' condition improves. However, the timing of LC after PTGBD remains controversial. METHODS: From 2004 to 2010, cholecystectomy after PTGBD was performed in 67 patients with AC. Group I members underwent LC within 72 h of PTGBD (n = 21), whereas

Pulmonary and Respiratory MedicineMedicine
2
Article|58 citations·2020
Risk prediction platform for pancreatic fistula after pancreatoduodenectomy using artificial intelligence
In Woong Han, Kyeongwon Cho, Youngju Ryu, Sang Hyun Shin, Jin Seok Heo, Dong Wook Choi, Myung Jin Chung, Oh Chul Kwon, Baek Hwan Cho
SJR Q1World Journal of GastroenterologyOA

This study is the first to predict POPF with multiple risk factors using AI. This platform is reliable (AUC 0.74), so it could be used to select patients who need especially intense therapy and to preoperatively establish an effective treatment strategy.

OncologyMedicine
3
Article|51 citations·2019
Validation of original and alternative fistula risk scores in postoperative pancreatic fistula
Youngju Ryu, Sang Hyun Shin, Dae Joon Park, Naru Kim, Jin Seok Heo, Dong Wook Choi, In Woong Han
SJR Q1Journal of Hepato-Biliary-Pancreatic SciencesOA

BACKGROUND: In 2013, the fistula risk score (FRS) was developed to assess the risk of clinically relevant postoperative pancreatic fistula (CR-POPF). In 2017, the alternative FRS (a-FRS) was proposed. The purpose of this study was to validate the original FRS (o-FRS) and a-FRS for CR-POPF in pancreaticoduodenectomy (PD). METHODS: From January 2007 to December 2016, 1,771 patients underwent PD for periampullary cancers. POPF was defined and classified according to the 2016 International Study Gro

OncologyMedicine
4
Article|47 citations·2020
The effects of sarcopenia and sarcopenic obesity after pancreaticoduodenectomy in patients with pancreatic head cancer
Youngju Ryu, Sang Hyun Shin, Jae‐Hun Kim, Woo Kyoung Jeong, Dae J. Park, Naru Kim, Jin Seok Heo, Dong Wook Choi, In Woong Han
SJR Q1HPB
PhysiologyMedicine
5
Article|45 citations·2013
Evaluation of Clinical Meaning of Histological Subtypes of Intraductal Papillary Mucinous Neoplasm of the Pancreas
Mee Joo Kang, Kyoung Bun Lee, Jin‐Young Jang, In Woong Han, Sun‐Whe Kim
SJR Q2Pancreas

Although histological subtypes are associated with the degree of dysplasia, histological subtypes have limited prognostic value for pancreatic IPMNs.

OncologyMedicine
6
Article|42 citations·2017
Excess intraoperative fluid volume administration is associated with pancreatic fistula after pancreaticoduodenectomy
In Woong Han, Hongbeom Kim, Jin-Seok Heo, Min Gu Oh, Yoo Shin Choi, Seung Eun Lee, Chang-Sup Lim
SJR Q3MedicineOA

Recent studies on perioperative fluid administration in patients undergoing pancreaticoduodenectomy (PD) have suggested that increased fluid loads are associated with worse perioperative outcomes. The purpose of this study was to investigate the relationship between intraoperative fluid (IOF) administration and postoperative pancreatic fistula (POPF), and to determine additional risk factors affecting pancreatic fistula in patients undergoing PD.From 2005 to 2014, a total of 182 patients with va

OncologyMedicine
7
Article|39 citations·2017
Ceruloplasmin as a prognostic marker in patients with bile duct cancer
In Woong Han, Jin‐Young Jang, Wooil Kwon, Taesung Park, Yongkang Kim, Kyoung Bun Lee, Sun‐Whe Kim
SJR Q2OncotargetOA

Ceruloplasmin is supposed to be related with advanced T stage and perineural invasion, having a possibility as a candidate prognostic marker for bile duct cancer.

SurgeryMedicine
8
Article|36 citations·2019
Nomogram for predicting postoperative pancreatic fistula
Yunghun You, In Woong Han, Dong Wook Choi, Jin Seok Heo, Youngju Ryu, Dae J. Park, Seong Ho Choi, Sunjong Han
SJR Q1HPB
OncologyMedicine
9
Article|35 citations·2017
Laparoscopic versus open distal pancreatectomy for nonfunctioning pancreatic neuroendocrine tumors: a large single-center study
Sang Hyup Han, In Woong Han, Jin Seok Heo, Seong Ho Choi, Dong Wook Choi, Sunjong Han, Yung Hun You
SJR Q1Surgical Endoscopy
EpidemiologyMedicine
10
Article|21 citations·2013
Clinicopathological analysis and prognosis of extrahepatic bile duct cancer with a microscopic positive ductal margin
In Woong Han, Jin‐Young Jang, Kyoung Bun Lee, Mee Joo Kang, Wooil Kwon, Jae Woo Park, Ye Rim Chang, Sun‐Whe Kim
SJR Q1HPBOA
SurgeryMedicine
11
Article|21 citations·2014
Role of resection for Bismuth type IV hilar cholangiocarcinoma and analysis of determining factors for curative resection
In Woong Han, Jin‐Young Jang, Mee Joo Kang, Wooil Kwon, Jae Woo Park, Ye Rim Chang, Sun‐Whe Kim
SJR Q2Annals of Surgical Treatment and ResearchOA

We recommend the criteria of CIR as bile duct variation type, length of hilum to contralateral second bile duct confluence, and extent of tumor infiltration over the second confluence for Bismuth type IV HCCA.

SurgeryMedicine
12
Article|14 citations·2014
Clinicopathologic Analysis of Gastrointestinal Stromal Tumors in Duodenum and Small Intestine
In Woong Han, Jin‐Young Jang, Kyoung Bun Lee, Mee Joo Kang, Wooil Kwon, Jae Woo Park, Ye Rim Chang, Hyuk‐Joon Lee, Kyu Joo Park, Sun‐Whe Kim
SJR Q1World Journal of Surgery

BACKGROUND: The prognosis about duodenal GISTs is debatable. The purpose of this study is to compare the characteristics and the prognostic factors in patients with gastrointestinal stromal tumor (GIST) located in the duodenum with those located in the small intestine. METHODS: One hundred-one patients with GIST located in the duodenum (n = 40), or small intestine (n = 61) underwent resection between 1996 and 2010. We analyzed clinicopathologic features, surgical outcomes, and prognostic factors

GastroenterologyMedicine
13
Article|14 citations·2020
Proposed Modification of Staging for Distal Cholangiocarcinoma Based on the Lymph Node Ratio Using Korean Multicenter Database
Yunghun You, Yong Chan Shin, Dong Wook Choi, Jin Seok Heo, Sang Hyun Shin, Naru Kim, Kee‐Taek Jang, Hongbeom Kim, Chang-Sup Lim, Sun Hee Chang, Kang Min Han, In Woong Han
SJR Q1CancersOA

The 8th American Joint Committee on Cancer (AJCC) staging system for distal cholangiocarcinoma (DCC) included a positive lymph node count (PLNC), but a comparison of the prognostic predictive power of PLNC and lymph node ratio (LNR) is still under debate. This study aimed to compare various staging models made by combining the abovementioned factors, identify the model with the best predictive power, and propose a modified staging system. We retrospectively reviewed 251 patients who underwent su

SurgeryMedicine
14
Article|14 citations·2022
Development of Nomograms for Predicting Prognosis of Pancreatic Cancer after Pancreatectomy: A Multicenter Study
So Jeong Yoon, Boram Park, Jaewoo Kwon, Chang-Sup Lim, Yong Chan Shin, Woohyun Jung, Sang Hyun Shin, Jin Seok Heo, In Woong Han
SJR Q1BiomedicinesOA

Surgical resection is the only curative treatment for pancreatic ductal adenocarcinoma (PDAC). Currently, the TNM classification system is considered the standard for predicting prognosis after surgery. However, the prognostic accuracy of the system remains limited. This study aimed to develop new predictive nomograms for resected PDAC. The clinicopathological data of patients who underwent surgery for PDAC between 2006 and 2015 at five major institutions were retrospectively reviewed; 885 patie

OncologyMedicine
15
Article|12 citations·2020
Long-term patient-reported outcomes following laparoscopic cholecystectomy
In Woong Han, Hyeon Kook Lee, Dae Joon Park, Yoo Shin Choi, Seung Eun Lee, Hongbeom Kim, Wooil Kwon, Jin‐Young Jang, Huisong Lee, Jin Seok Heo
SJR Q3MedicineOA

Several studies have reported short-term results for post-cholecystectomy symptoms and quality of life (QoL). However, reports on long-term results are still limited. This study aimed to identify risk factors affecting short- and long-term patient-reported outcome (PRO) following laparoscopic cholecystectomy.From 2016 to 2017, a total of 476 patients from 5 institutions were enrolled. PRO was examined using the Numeric Rating Scale (NRS) pain score and the Gastrointestinal (GI) QoL Index questio

Pulmonary and Respiratory MedicineMedicine

Research Areas

OncologySurgeryPulmonary and Respiratory MedicineEpidemiologyPhysiologyRadiology, Nuclear Medicine and Imaging

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