Jae-Ho Cho

Recent communication research concerning participatory politics has found that the effects of media, especially campaign ads, conventional news, and online political resources, are largely mediated through interpersonal discussion about politics. This article extends this line of theorizing about the role of political conversation in citizen competence by testing an O-S-R-O-R model of campaign communication mediation, a modification and extension of the longstanding O-S-O-R model of communicatio

Abstract Research on print and broadcast media shows differences in cognitive and affective responses. We extend that research by combining content analysis and survey methods to examine medium differences in the emotional tone of coverage concerning the September 11th terrorist attacks, and audience differences in emotional reactions to the attacks. A computer- aided content analysis of national television and newspaper transcripts demonstrates that television news was consistently more emotion

This study examines algorithm effects on user opinion, utilizing a real-world recommender algorithm of a highly popular video-sharing platform, YouTube. We experimentally manipulate user search/watch history by our custom programming. A controlled laboratory experiment is then conducted to examine whether exposure to algorithmically recommended content reinforces and polarizes political opinions. Results suggest that political self-reinforcement, as indicated by the political emotion-ideology al

Radiation-induced lung injury (RILI), including acute radiation pneumonitis and chronic radiation-induced lung fibrosis, is the most common side effect of radiation therapy. RILI is a complicated process that causes the accumulation, proliferation, and differentiation of fibroblasts and, finally, results in excessive extracellular matrix deposition. Currently, there are no approved treatment options for patients with radiation-induced pulmonary fibrosis (RIPF) partly due to the absence of effect

Over the past decade, various online communication platforms have empowered citizens to express themselves politically. Although the political impact of online citizen expression has drawn considerable attention, research has largely focused on whether and how citizen-generated messages influence the public as an information alternative to traditional news outlets. The present study aims to provide a new perspective on understanding citizen expression by examining its political implications for

DNA immunization induces CD8(+) CTL responses by bone marrow-derived APCs, which are directly transfected with a plasmid DNA and/or acquire Ags from DNA-transfected non-APCs. To investigate the relative contribution of DNA-transfected APCs vs non-APCs to the initiation of CD8(+) T cell responses, we used tissue-specific promoter-directed gene expression and adoptive transfer systems in gene gun DNA immunization. In this study, we demonstrated that non-APC-specific gene expressions induced signif

PURPOSE: Lung fibrosis is a major side effect experienced by patients after lung cancer radiotherapy. However, effective protection strategies and underlying treatment targets remain unclear. In an effort to improve clinical outcomes, pharmacologic treatment of fibrosis is becoming increasingly popular; however, no ideal therapeutic strategy is yet available. EXPERIMENTAL DESIGN: We used a mouse model to irradiate high focal (90 or 75 Gy) to 3-mm volume of the left lung. Lung tissues of mice wer

Our data suggest that radiotherapy to the primary tumor was associated with improved OS and BCFFS in metastatic prostate cancer. The results of this study warrant prospective controlled clinical trials of this approach in stage IV prostate cancer patients with limited extent of bone metastasis and good performance status.

This paper investigates relationships between community characteristics and levels of knowledge and participation examined at both the individual and the community levels. This research extends the knowledge gap concept to a parallel phenomenon, the participation gap. Results from the Social Capital Benchmark Survey 2000 showed that community density, education, and cohesion were significant positive predictors of knowledge but less consistent predictors of participation at the individual level.