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Jae Hwan Lee

Seoul National University · 医学

研究室紹介

Professor Jae Hwan Lee's research lab specializes in clinical and translational studies focusing on medical imaging, particularly in hepatocellular carcinoma (HCC) diagnosis using multidetector computed tomography (MDCT), and the impact of various clinical factors on cancer outcomes. The lab also investigates complications related to vascular access devices in oncology patients, such as peripherally inserted central catheter (PICC)-associated bloodstream infections, and explores the effects of environmental and biological factors—like UVB radiation and ozone interactions with sampling materials—on human health and clinical testing accuracy. Additionally, the lab examines ophthalmic conditions exacerbated by surgical interventions, such as LASEK in patients with corneal dystrophies.

medical imagingoncologyvascular accesscorneal dystrophyenvironmental sampling artifacts

Research Overview

Papers
152
Total Citations
1,365
Papers (5y)
46
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
46total
2022
2023
2024
2025
2026
Citations per year (5y)
125total
20222023202420252026

Selected Papers

15
1
Article|113 citations·2012
Enhancement patterns of hepatocellular carcinomas on multiphasic multidetector row CT: comparison with pathological differentiation
Jae Hwan Lee, Jeong Min Lee, S. J. Kim, Jeong‐Hwa Baek, Seongjin Yun, Kyung Woo Kim, Joon Koo Han, Byung Ihn Choi
SJR Q1British Journal of Radiology

A typical enhancement of HCCs on MDCT was not unusual (43.6%) and WD and PD HCCs account for most of the atypical enhancement patterns. Early washout favoured MD and PD HCCs rather than WD HCCs, whereas in our study the presence of intratumoral aneurysm was a highly specific finding for PD HCC.

HepatologyMedicine
2
Article|81 citations·2006
Ozone Artifacts and Carbonyl Measurements Using Tenax GR, Tenax TA, Carbopack B, and Carbopack X Adsorbents
Jae Hwan Lee, Stuart Batterman, Chunrong Jia, Sergei M. Chernyak
SJR Q2Journal of the Air & Waste Management AssociationOA

Four popular thermally desorbable adsorbents used for air sampling (Tenax TA, Tenax GR, Carbopack B, and Carbopack X) are examined for the potential to form artifacts with ozone (O3) at environmental concentrations. The performance of these adsorbents for the ketone and aldehyde species identified as O3-adsorbent artifacts was also characterized, including recovery, linearity, and method detection limits (MDLs). Using gas chromatography/mass spectrometry, 13 different artifacts were identified a

Biomedical EngineeringEngineering
3
Article|72 citations·2002
Acute effects of UVB radiation on the proliferation and differentiation of keratinocytes
Jae Hwan Lee, Hyun-Joon An, Jin Ho Chung, Kyae Hyung Kim, Hee Chul Eun, K. H. Cho
SJR Q2Photodermatology Photoimmunology & PhotomedicineOA

PURPOSE: The effects of UVB radiation on the proliferation and differentiation of epidermal keratinocytes were investigated with respect to timing, dosage, and repeated exposures. METHODS: Nine healthy volunteers were placed into three subgroups and exposed to UVB radiation on buttock skin using a Waldmann UV 800 unit fitted with Philips TL-20W/12 fluorescent lamps. Three volunteers were given 2 MED of UVB and biopsied at: pre-exposure, 24, 48 and 72 h after UVB exposure. For three volunteers, 1

DermatologyMedicine
4
Article|45 citations·2005
Comparative study of the subserosal versus submucosal dye injection method for sentinel node biopsy in gastric cancer
Jae Hwan Lee, Keun Won Ryu, C.G. Kim, S.K. Kim, Il Ju Choi, Young‐Woo Kim, Hee Jin Chang, Jae-Moon Bae, Eun Kyung Hong
SJR Q1European Journal of Surgical Oncology
Pulmonary and Respiratory MedicineMedicine
5
Article|33 citations·2019
Prevalence and predictors of peripherally inserted central catheter-associated bloodstream infections in adults: A multicenter cohort study
Jae Hwan Lee, Eung Tae Kim, Dong Jae Shim, Il Jung Kim, Jong Hyun Byeon, In Joon Lee, Hyun Beom Kim, Young Ju Choi, Jin Hong Lee
SJR Q1PLoS ONEOA

Our results indicated that risk factors associated with PBSI included the number of catheter lumens, the use of PICCs for chemotherapy, and the hospital length of stay. Furthermore, PBSI-related death was common in patients undergoing chemotherapy, diabetics, and elderly patients.

Emergency Medical ServicesHealth Professions
6
Article|29 citations·2008
Exacerbation of Granular Corneal Dystrophy Type II (Avellino Corneal Dystrophy) After LASEK
Jae Hwan Lee, Elmer Y. Tu, Dong Ho Lee, Christopher Seungkyu Lee, Woon Cho Kim, Eung Kweon Kim
SJR Q1Journal of Refractive Surgery

PURPOSE: To report cases of granular corneal dystrophy type II (Avellino corneal dystrophy) that were exacerbated by uncomplicated laser epithelial keratomileusis (LASEK) for myopia. METHODS: Eight patients (15 eyes) with granular corneal dystrophy type II who underwent LASEK were examined by DNA sequencing, slit-lamp microscopy, and confocal microscopy. RESULTS: The number and density of the opacities increased after LASEK. Best spectacle-corrected visual acuity decreased after LASEK as the den

Radiology, Nuclear Medicine and ImagingMedicine
7
Article|28 citations·2020
Prevalence and predictors of peripherally inserted central venous catheter associated bloodstream infections in cancer patients
Jae Hwan Lee, Min Uk Kim, Eung Tae Kim, Dong Jae Shim, Il Jung Kim, Jong Hyun Byeon, Hyun Beom Kim
SJR Q3MedicineOA

Despite increasing use, the exact prevalence and predictors of peripherally inserted central catheter-associated bloodstream infection (PICC-CLABSI) in hospitalized patients with cancer are not elucidated.This retrospective cohort study included consecutive patients who underwent peripherally inserted central catheter (PICC) placement in 4 institutions (during 12 months in 3 hospitals and 10 months in 1 hospital). The prevalence of PICC-CLABSI was evaluated. The association between predictors an

Emergency Medical ServicesHealth Professions
8
Article|27 citations·2012
MRI features of serous oligocystic adenoma of the pancreas: differentiation from mucinous cystic neoplasm of the pancreas
Jae Hwan Lee, J K Kim, Tae Hee Kim, Mi‐Suk Park, Jeong‐Sik Yu, J-Y Choi, Jang‐Hee Kim, Yun-Bae Kim, K. W. Kim
SJR Q1British Journal of RadiologyOA

SOA could be differentiated from MCN by identifying the imaging features of lobulated contour with multiple clustered cyst configurations and homogeneity of each locule in T(1) weighted MR images.

OncologyMedicine
9
Article|26 citations·2019
Antitumor Effects of Intra-Arterial Delivery of Albumin-Doxorubicin Nanoparticle Conjugated Microbubbles Combined with Ultrasound-Targeted Microbubble Activation on VX2 Rabbit Liver Tumors
Jae Hwan Lee, Hyungwon Moon, Hyounkoo Han, In Joon Lee, Doyeon Kim, Hak Jong Lee, Shin‐Woo Ha, Hyuncheol Kim, Jin Wook Chung
SJR Q1CancersOA

Image-guided intra-arterial therapies play a key role in the management of hepatic malignancies. However, limited clinical outcomes suggest the need for new multifunctional drug delivery systems to enhance local drug concentration while reducing systemic adverse reactions. Therefore, we developed the albumin-doxorubicin nanoparticle conjugated microbubble (ADMB) to enhance therapeutic efficiency by sonoporation under exposure to ultrasound. ADMB demonstrated a size distribution of 2.33 ± 1.34 µm

Biomedical EngineeringEngineering
10
Article|26 citations·2011
Effects of Roasting Conditions on the Physicochemical Properties and Volatile Distribution in Perilla Oils ( Perilla frutescens var. japonica )
Minhee Park, Nam Gyu Seol, Pahn‐Shick Chang, Suk Hoo Yoon, Jae Hwan Lee
SJR Q1Journal of Food Science

UNLABELLED: Perilla seeds have more than 60% of α-linolenic acid, one of omega-3 essential fatty acids. Headspace volatiles and physicochemical properties including color, fluorescence intensity, and the oxidation products in perilla oil (PO) from perilla seeds roasted at different conditions were analyzed. Roasting temperature was 150, 170, 190, and 210°C, and roasting time was 15 and 30 min at each roasting temperature. PO from higher roasting temperature and longer roasting time had lower L*

SurgeryMedicine
11
Article|22 citations·2021
Short-term Results of Transcatheter Arterial Embolization for Chronic Medial Epicondylitis Refractory to Conservative Treatment: A Single-Center Retrospective Cohort Study
Jae Hwan Lee, Dong Hyun Kim, Sang-Hwan Lee, Jin Ho Hwang, Soo Buem Cho, Min Uk Kim, Young So, Young Jae Kim, Won Seok Choi, Chang Jin Yoon
SJR Q2CardioVascular and Interventional Radiology
Orthopedics and Sports MedicineMedicine
12
Article|20 citations·2020
Transhepatic stent placement for portal vein obstruction after hepatobiliary and pancreatic surgery: long-term efficacy and risk factor for stent failure
Jae Hwan Lee, Chang Jin Yoon, Won Seok Choi
SJR Q1European Radiology
Pulmonary and Respiratory MedicineMedicine
13
Article|20 citations·2009
Learning Curve for Identification of Sentinel Lymph Node Based on a Cumulative Sum Analysis in Gastric Cancer
Jae Hwan Lee, Keun Won Ryu, S.E. Lee, Soo‐Jeong Cho, J.Y. Lee, C.G. Kim, Il Ju Choi, Myeong‐Cherl Kook, M.J. Kim, S.R. Park, J.S. Lee, Byung‐Ho Nam
SJR Q2Digestive Surgery

BACKGROUND/AIMS: Lymph node metastasis is the most important point to consider when deciding on the modality of resection in patients with early gastric cancer. This study was conducted to evaluate the learning curve for identification of sentinel lymph nodes in patients with gastric cancer. METHODS: The investigators included the results from 2 prospective series of sentinel lymph node mapping. Cumulative sum (CUSUM) analysis was performed to assess the learning curves for identification of sen

Pulmonary and Respiratory MedicineMedicine
14
Article|14 citations·2012
An Optimized Adsorbent Sampling Combined to Thermal Desorption GC-MS Method for Trimethylsilanol in Industrial Environments
Jae Hwan Lee, Chunrong Jia, Yong Doo Kim, Hong Hyun Kim, Tien Thang Pham, Young Seok Choi, Young Un Seo, Ike Woo Lee
SJR Q3International Journal of Analytical ChemistryOA

Trimethylsilanol (TMSOH) can cause damage to surfaces of scanner lenses in the semiconductor industry, and there is a critical need to measure and control airborne TMSOH concentrations. This study develops a thermal desorption (TD)-gas chromatography (GC)-mass spectrometry (MS) method for measuring trace-level TMSOH in occupational indoor air. Laboratory method optimization obtained best performance when using dual-bed tube configuration (100 mg of Tenax TA followed by 100 mg of Carboxen 569), n

Process Chemistry and TechnologyChemical Engineering
15
Article|13 citations·2022
Comparison of n-butyl-2-cyanoacrylate and polyvinyl alcohol particles for bronchial artery embolisation in primary lung cancer: a retrospective cohort study
Jae Hwan Lee, Chang Jin Yoon, Yun Su Jung, Won Seok Choi, Chong-ho Lee, Guy Mok Lee
SJR Q1Respiratory ResearchOA

Abstract Background Bronchial artery embolisation (BAE) is an effective treatment option to control haemoptysis in primary lung cancer. However, no studies have investigated optimal embolisation material for BAE in lung cancer patients. Thus, this study aimed to compare the safety and efficacy of BAE performed using n -butyl-2-cyanoacrylate (NBCA) and polyvinyl alcohol (PVA) particles in primary lung cancer patients to determine which embolic material is better for patients with haemoptysis. Met

GeneticsMedicine

Research Areas

Pulmonary and Respiratory MedicineSurgeryHepatologyBiomedical EngineeringEmergency Medical ServicesOncology

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