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Jae-hyun Jeong

Korea University · 医学

研究室紹介

Professor Jae-hyun Jeong's research lab focuses on the intersection of metabolic and musculoskeletal health in aging populations, particularly postmenopausal women. The lab investigates hormonal influences on osteoarthritis, gout, and metabolic syndrome, with an emphasis on how menopausal hormone therapy affects serum uric acid levels, joint health, and mental health outcomes. Key research directions include the epidemiological and physiological links between hormonal changes, chronic inflammation, and systemic conditions such as insulin resistance, kidney disease, and mental health disorders. The lab utilizes large-scale national health surveys to explore population-level trends and clinical interventions, including aquatic exercise for respiratory function in spinal cord injury patients.

osteoarthritismenopausal hormone therapyuric acidmetabolic syndromemental health in chronic disease

Research Overview

Papers
136
Total Citations
1,080
Papers (5y)
41
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
41total
2022
2023
2024
2025
2026
Citations per year (5y)
111total
20222023202420252026

Selected Papers

15
1
Review|78 citations·2018
Endovascular Versus Open Surgical Intervention in Patients with Takayasu's Arteritis: A Meta-analysis
Jae Hyun Jung, Young Ho Lee, Gwan Gyu Song, Han Saem Jeong, Jae‐Hoon Kim, Sung Jae Choi
SJR Q1European Journal of Vascular and Endovascular Surgery
Pulmonary and Respiratory MedicineMedicine
2
Article|68 citations·2018
Knee osteoarthritis and menopausal hormone therapy in postmenopausal women: a nationwide cross-sectional study
Jae Hyun Jung, Cho Hee Bang, Gwan Gyu Song, Cholhee Kim, Jae‐Hoon Kim, Sung Jae Choi
SJR Q1Menopause The Journal of The North American Menopause Society

OBJECTIVE: The incidence of osteoarthritis (OA) increases after menopause, and may be related to hormonal changes in women. Estrogen deficiency is known to affect the development of OA, and menopausal hormone therapy (MHT) is suggested to be related to the development of OA. However, the relationship between knee OA and MHT remains controversial. The association between knee OA prevalence and MHT was investigated using large-scale national data. METHODS: Data were collected from 4,766 postmenopa

RheumatologyMedicine
3
Article|64 citations·2007
Fast and sensitive DNA analysis using changes in the FRET signals of molecular beacons in a PDMS microfluidic channel
Jae Hyun Jung, Lingxin Chen, Sang Yup Lee, Sungyong Kim, Gi Hun Seong, Jaebum Choo, Eun Kyu Lee, Chil Hwan Oh, Sang‐Hoon Lee
SJR Q2Analytical and Bioanalytical Chemistry
Molecular BiologyBiochemistry, Genetics and Molecular Biology
4
Article|57 citations·2017
Serum uric acid levels and hormone therapy type: a retrospective cohort study of postmenopausal women
Jae Hyun Jung, Gwan Gyu Song, Young Ho Lee, Jae‐Hoon Kim, Myung Han Hyun, Sung Jae Choi
SJR Q1Menopause The Journal of The North American Menopause Society

OBJECTIVE: Serum uric acid levels increase in postmenopausal women, but decrease when hormone therapy (HT) is administered. No study has, however, evaluated the effects of different types of HT on serum uric acid levels. We therefore examined whether estrogen therapy (ET), estrogen plus progestogen therapy (EPT), and tibolone use affected serum uric acid levels in this population. METHODS: We performed a retrospective cohort study of postmenopausal women. From 2005 to 2015, postmenopausal women

NephrologyMedicine
5
Article|45 citations·2017
Association between osteoarthritis and mental health in a Korean population: a nationwide study
Jae Hyun Jung, Hongdeok Seok, Jae‐Hoon Kim, Gwan Gyu Song, Sung Jae Choi
SJR Q3International Journal of Rheumatic DiseasesOA

AIM: Osteoarthritis (OA) is a chronic disease and has become a major health problem in recent years. OA causes chronic pain and disability and can induce mental disorders such as stress perception, depression and suicidal ideation. We investigated the incidence of perceived stress, depressed mood and suicidal ideation in OA patients, using the 2010-2012 Korea National Health and Nutrition Examination Survey (KNHANES). METHOD: A total of 8271 participants were included (3580 male and 4691 female)

RheumatologyMedicine
6
Article|42 citations·2016
Metabolic syndrome: prevalence and risk factors in Korean gout patients
Jae Hyun Jung, Gwan Gyu Song, Jong Dae Ji, Young Ho Lee, Jae‐Hoon Kim, Young Ho Seo, Sung Jae Choi
SJR Q2The Korean Journal of Internal MedicineOA

The prevalence of metabolic syndrome in patients with gout was 50.8%, which is higher than the prevalence in the general Korean population. Hyperuricemia in gout patients was correlated with metabolic syndrome and CKD. Insulin resistance may provide clues to better understand the relationship between metabolic syndrome, CKD, and gout.

NephrologyMedicine
7
Article|39 citations·2017
The Association between Osteoarthritis and Occupational Clusters in the Korean Population: A Nationwide Study
Hongdeok Seok, Sung Jae Choi, Jin‐Ha Yoon, Gwan Gyu Song, Jong‐Uk Won, Jae‐Hoon Kim, Jaehoon Roh, Jae Hyun Jung
SJR Q1PLoS ONEOA

Osteoarthritis (OA) is a considerable health problem worldwide. It is known to be associated with certain occupational risk factors. We examined the prevalence rate of OA by occupational cluster. Data were collected from the Korea National Health and Nutrition Examination Surveys (2010-2013). The total number of unweighted sample size was 9,905 participants: 4,460 men and 5,445 women, and OA prevalence was 5.3% and 18.4% respectively. OA patients were defined as participants with knee/hip joint

RheumatologyMedicine
8
Article|32 citations·2018
The association between osteoarthritis and sleep duration in Koreans: a nationwide cross-sectional observational study
Jae Hyun Jung, Hongdeok Seok, Sung Jae Choi, Junwoo Bae, Sang Hoon Lee, Moo Hwa Lee, Jae‐Hoon Kim, Gwan Gyu Song
SJR Q2Clinical Rheumatology
Experimental and Cognitive PsychologyPsychology
9
Article|31 citations·2020
A comparative pilot study of oral diacerein and locally treated diacerein-loaded nanoparticles in a model of osteoarthritis
Jae Hyun Jung, Sung Eun Kim, Hak Jun Kim, Kyeongsoon Park, Gwan Gyu Song, Sung Jae Choi
SJR Q1International Journal of Pharmaceutics
RheumatologyMedicine
10
Article|25 citations·2014
The Effects of Aquatic Exercise on Pulmonary Function in Patients with Spinal Cord Injury
Jae Hyun Jung, Eun-Jung Chung, Kyoung Kim, Byoung‐Hee Lee, Jiyeun Lee
Journal of Physical Therapy ScienceOA

[Purpose] The purpose of this study was to determine the effects of aquatic exercise on pulmonary function of patients with spinal cord injury. [Subjects] The subjects were randomly allocated to an aqua group (n=10) and a land group (n=10). [Methods] Both groups trained for 60 minutes, 3 times a week for 8 weeks. Pulmonary function was assessed by measuring the forced vital capacity (FVC), forced expiratory flow rate (FER), force expiratory volume at one second (FEV1) and force expiratory volume

Pathology and Forensic MedicineMedicine
11
Article|23 citations·2006
Quantitative Determination of Nicotine in a PDMS Microfluidic Channel Using Surface Enhanced Raman Spectroscopy
Jae Hyun Jung
SJR Q2Bulletin of the Korean Chemical SocietyOA

Rapid and highly sensitive determination of nicotine in a PDMS microfluidic channel was investigated using surface enhanced Raman spectroscopy (SERS). A three-dimensional PDMS microfluidic channel was fabricated for this purpose. This channel shows a high mixing efficiency because the transverse and vertical dispersions of the fluid occur simultaneously through the upper and lower zig zag-type blocks. A higher efficiency of mixing could also be obtained by splitting each of the confluent streams

Biomedical EngineeringEngineering
12
Article|19 citations·2018
Is knee osteoarthritis related to coffee drinking? A nationwide cross-sectional observational study
Cho Hee Bang, Cholhee Kim, Jae‐Hoon Kim, Sung Jae Choi, Gwan Gyu Song, Jae Hyun Jung
SJR Q2Clinical Rheumatology
RehabilitationMedicine
13
Review|19 citations·2016
Association of Interleukin 10 Gene Polymorphisms with Autoimmune Thyroid Disease: Meta‐Analysis
Jae Hyun Jung, Gwan Gyu Song, Jae‐Hoon Kim, Sangbum Choi
SJR Q2Scandinavian Journal of ImmunologyOA

The aim of this study was to perform a meta-analysis of eligible studies and to derive a precise estimate of the association between interleukin 10 (IL10) polymorphisms and susceptibility to autoimmune thyroid disease (AITD). Meta-analyses were conducted on the associations between AITD and the -1082 G/A (rs1800896), -819 C/T (rs1800871) and -592 C/A (rs1800872) polymorphisms in IL10, and the haplotype of these polymorphisms and AITD. A total of 2903 AITD patients and 3060 controls in 10 eligibl

GeneticsBiochemistry, Genetics and Molecular Biology
14
Article|19 citations·2019
Relationship of rheumatoid arthritis and coronary artery disease in the Korean population: a nationwide cross-sectional study
Tae Hyub Lee, Gwan Gyu Song, Sung Jae Choi, Hongdeok Seok, Jae Hyun Jung
SJR Q3Advances in RheumatologyOA

BACKGROUND: Rheumatoid arthritis (RA) is known to be associated with coronary artery diseases (CAD). Previous studies of the association between RA and CAD were reported mainly in non-Asian groups. We aimed to examine the prevalence of RA and the relationship between RA and CAD in South Korea. METHODS: We conducted a nationwide cross-sectional study by using the Korea National Health and Nutrition Examination Survey, which collected data for four years between 2008 and 2012. A total of 25,828 el

RheumatologyMedicine
15
Article|16 citations·2017
Clinical Outcomes of Standard Triple Therapy Plus Probiotics or Concomitant Therapy for Helicobacter pylori Infection
Jae Hyun Jung, In Kuk Cho, Chang Hee Lee, Gwan Gyu Song, Ji Hyun Lim
SJR Q1Gut and LiverOA

STP and CT are encouragingly efficacious as first-line treatments for <i>H. pylori</i> infection. Therefore, adding probiotics to STT may be a feasible option to avoid side effects.

SurgeryMedicine

Research Areas

RheumatologySurgeryPulmonary and Respiratory MedicineOphthalmologyPhysiologyHematology

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