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Jaeseung Shin

Korea University · 医学

研究室紹介

Professor Jaeseung Shin's research lab specializes in thoracic surgery and thoracic oncology, with a focus on minimally invasive surgical techniques such as video-assisted thoracoscopic surgery (VATS) and innovative approaches for treating thoracic diseases. The lab investigates rare thoracic tumors, including giant cell tumors of the rib, extramedullary plasmacytomas, and lymphomatoid granulomatosis, emphasizing diagnostic challenges and novel therapeutic strategies. Additionally, the lab explores molecular mechanisms underlying gene regulation in cancer, particularly retinoic acid response in HOXA-7, linking basic science to clinical applications. Their work bridges clinical surgery, oncology, and molecular biology to improve patient outcomes in complex thoracic conditions.

thoracic surgeryminimally invasive surgerythoracic oncologyrare tumorsgene regulation

Research Overview

Papers
66
Total Citations
575
Papers (5y)
10
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
10total
2019
2020
2021
2023
2024
Citations per year (5y)
23total
20192020202120232024

Selected Papers

15
1
Article|132 citations·2010
Minimally invasive repair of pectus excavatum: A novel morphology-tailored, patient-specific approach
Hyung Joo Park, Jin Yong Jeong, Won-Min Jo, Jae Seung Shin, In Sung Lee, Kwang Taik Kim, Young Ho Choi
SJR Q1Journal of Thoracic and Cardiovascular SurgeryOA
SurgeryMedicine
2
Article|48 citations·2003
A Simple Technique for the Thoracoscopic Plication of the Diaphragm
Znuke Hwang, Jae Seung Shin, Yang Hyun Cho, Kyung Hoon Sun, In Sung Lee
SJR Q1CHEST Journal
SurgeryMedicine
3
Article|35 citations·2017
Video-assisted thoracoscopic surgery for intrathoracic first rib resection in thoracic outlet syndrome
Jinwook Hwang, Byung-Ju Min, Won-Min Jo, Jae Seung Shin
SJR Q2Journal of Thoracic DiseaseOA

VATS-IFRR was safe and had several advantages. Thus, VATS-IFRR is a minimally invasive surgical option suitable for treating selective cases of TOS.

Radiology, Nuclear Medicine and ImagingMedicine
4
Article|30 citations·2018
Non-intubated thoracoscopic bullectomy under sedation is safe and comfortable in the perioperative period
Jinwook Hwang, Jae Seung Shin, Joo Hyung Son, Too Jae Min
SJR Q2Journal of Thoracic DiseaseOA

BACKGROUND: Non-intubated thoracoscopic surgery can be performed under sedation using adjuvant regional anesthesia, however, the benefits of non-intubated thoracoscopic surgery under sedation have not yet been completely verified. In this study, we compare the perioperative safety and pain complaints of sedation without intubation in thoracoscopic bullectomy with that of conventional general anesthesia with double-lumen intubation and mechanical ventilation. METHODS: Forty-one patients with prim

Anesthesiology and Pain MedicineMedicine
5
Article|28 citations·2002
Giant Cell Tumor Originating from the Anterior Arc of the Rib
Jae Seung Shin, In Sung Lee, Ae Ree Kim, Baek Hyun Kim
SJR Q2Journal of Korean Medical ScienceOA

We report a case of giant cell tumor originating from the anterior arc of the rib. The tumor and the surrounding chest wall were completely resected, and the chest wall defect was covered with Marlex mesh. Giant cell tumor of the bone usually originates from the epiphysis of long bones. Even when the tumor occur in ribs, it usually occur in the posterior aspect. However, giant cell tumor should be included in the differential diagnosis of a tumor originating from the anterior arc of the ribs.

RheumatologyMedicine
6
Article|23 citations·2005
A Case of Extramedullary Plasmacytoma Arising from the Posterior Mediastinum
Sung Yong Lee, Je Hyeong Kim, Jae Seung Shin, Chol Shin, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo
SJR Q2The Korean Journal of Internal MedicineOA

Plasmacytomas are a localized proliferation of plasma cells in the bone marrow, and are less frequently seen in extraosseous organs or tissues. Extramedullary plasmacytoma is a rare malignant neoplasm, and is especially uncommon when it arises from the mediastinum. Here, we report on a case of posterior mediastinal extramedullary plasmacytoma in a 64-year-old man. He was admitted with an asymptomatic right apical mediastinal mass, which was provisionally diagnosed as a neurogenic mass. However,

HematologyMedicine
7
Article|21 citations·2002
Retinoic acid response element in HOXA-7 regulatory region affects the rate, not the formation of anterior boundary expression
Myoung Hee Kim, Jae Seung Shin, Sungdo Park, Man‐Wook Hur, Mi‐Ok Lee, Hyung Woo Park, Chul-Sang Lee
SJR Q3The International Journal of Developmental BiologyOA

Since it is known that a 307 bp fragment of the position specific regulatory element of human HOXA-7 contains two (DR3 and DR5) retinoic acid response elements (RAREs) at its 3' end, we constructed several deletion constructs containing different numbers of RAREs and examined their effects in vitro and in vivo. The 5' deletion constructs, BM112 and OM213, retaining both RAREs, were highly responsible (about 8 fold induction) for RA in F9 teratocarcinoma cells, versus NM307 (4-5 fold). The constr

Molecular BiologyBiochemistry, Genetics and Molecular Biology
8
Article|19 citations·2009
A Case of Pulmonary Lymphomatoid Granulomatosis Successfully Treated by Combination Chemotherapy with Rituximab
Ki Hwan Jung, Hwa Jung Sung, Jeong Hyeon Lee, Ki Yeol Lee, Jae Seung Shin, Kyung Min Kim, Young‐Sik Kim, Chol Shin, Je Hyeong Kim
SJR Q3Chemotherapy

Lymphomatoid granulomatosis (LYG) is a rare angiocentric and angiodestructive lymphoproliferative disease characterized by Epstein-Barr virus-positive B cells admixed with reactive T cells. LYG most commonly affects the lung but can also involve other extrapulmonary sites. Pulmonary LYG usually presents as multiple pulmonary nodules with rapid progression and excavation. It can mimic various infectious diseases, vasculitis or metastatic malignancy and is difficult to be diagnosed clinically. Sta

Pathology and Forensic MedicineMedicine
9
Article|17 citations·2007
Successful extracorporeal life support after potentially fatal pulmonary oedema caused by inhalation of nitric and hydrofluoric acid fumes
Jae Seung Shin, Sung-Woo Lee, Nak-Hoon Kim, Jon-Su Park, Kwang Ja Kim, Sung‐Hyuk Choi, Yun-Sik Hong
SJR Q1Resuscitation
Emergency MedicineMedicine
10
Article|16 citations·2007
Fibromuscular Dysplasia of Bilateral Brachial Arteries Treated with Surgery and Consecutive Thrombolytic Therapy
Jae Seung Shin, Eun Mee Han, Byung Zoo Min, Won Jae Jung, Won-Min Jo, In Sung Lee
SJR Q2Annals of Vascular Surgery
Pulmonary and Respiratory MedicineMedicine
11
Article|15 citations·2006
Ventricular Assist Device Implantation Using a Right Thoracotomy
Ho Sung Son, Kyung Sun, Chang Mo Hwang, Yong Hu Fang, Choon Hak Lim, Hye Won Lee, Sung‐Min Park, Jae Seung Shin, Kwang Taik Kim, Hyoung Mook Kim
SJR Q1ASAIO Journal

Most patients needing implantation of a ventricular assist device (VAD) require repeated sternotomy; some after cardiac surgery, and others later for heart transplantation. The purpose of this study was to establish the right thoracotomy technique as an alternative for VAD implantation to reduce repeated sternotomy-related morbidity and mortality. We performed a right thoracotomy in animals, preclinical cadaver fitting tests, and a clinical case. A total of 20 various animals underwent right tho

Biomedical EngineeringEngineering
12
Article|14 citations·2005
Supradiaphragmatic Bronchogenic Cyst Extending Into the Retroperitoneum
Won-Min Jo, Jae Seung Shin, In Sung Lee
SJR Q1The Annals of Thoracic Surgery
NeurologyMedicine
13
Article|13 citations·2003
Korean Artificial Heart (AnyHeart): An Experimental Study and the First Human Application
Kyung Sun, Ho Sung Son, Jae Seung Jung, Bong Kyu Cheong, Jae Seung Shin, Kwang Taik Kim, Hye Won Lee, Sang Su Ahn, Sung Young Park, Hye Jung Oh, Hwan Sung Lee, Eun Bo Shim
SJR Q2Artificial OrgansOA

A Korean artificial heart (AnyHeart) has been implanted in 29 various animals (52-470 kg) to evaluate hemodynamic performance and electromechanical stability. Most were implantable biventricular assist devices in use. A right thoracotomy approach has been a standard technique of implantation. A preclinical fitting test was also performed to observe anatomical feasibility and to compare surgical techniques in 10 human cadavers. The first case of human application was made as a lifesaving procedur

SurgeryMedicine
14
Article|13 citations·2006
Mid-term Outcomes of Side-to-Side Stapled Anastomosis in Cervical Esophagogastrostomy
Won-Min Jo, Jae Seung Shin, In Sung Lee
SJR Q2Journal of Korean Medical ScienceOA

This study was conducted to evaluate the mid-term results of cervical esophagogastric anastomosis using a side-to-side stapled anastomosis method for treatment of patients with malignant esophageal disease. A total of 13 patients were reviewed retrospectively from January 2001 to November 2005 who underwent total esophagectomy through a right thoracotomy, gastric tube formation through a midline laparotomy and finally a cervical esophagogastric anastomosis. Average patient age was 62.6 yr old an

SurgeryMedicine
15
Article|10 citations·2002
Acute Descending Aortic Dissection Associated with Coarctation in Adult
Jae Seung Shin, Kyung Sun, Wan Joo Shim, Kwang Taik Kim, Hyoung Mook Kim
SJR Q3Asian Cardiovascular and Thoracic Annals

A 44-year-old man with congenital aortic coarctation experienced acute dissection that crossed the coarctation and extended to both iliac arteries. The primary entry of the dissection was proximal to the coarctation segment, just below the origin of the left subclavian artery. Surgical procedures involved resection of the diseased segment including the coarctation, and graft interposition.

EpidemiologyMedicine

Research Areas

Pulmonary and Respiratory MedicineSurgeryBiomedical EngineeringEpidemiologyRheumatologyRadiology, Nuclear Medicine and Imaging

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