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Jeong Woo Han

Yonsei University · 医学

研究室紹介

Professor Jeong Woo Han's research lab specializes in oncology and long-term survivorship following childhood and breast cancer, with a strong focus on minimizing treatment-related late effects and improving quality of life. The lab investigates surgical techniques that preserve critical anatomical structures—such as arm lymph nodes in breast cancer patients—while reducing complications like lymphedema. It also explores late effects in childhood cancer survivors, including bone mineral density loss and endocrine dysfunction, and evaluates innovative treatment strategies such as alternating intravenous and intra-arterial chemotherapy in retinoblastoma to enhance eye salvage and reduce metastatic risk. Additionally, the lab addresses rare but critical complications in hematopoietic stem cell transplant patients, such as Wernicke’s encephalopathy, emphasizing early detection and intervention.

cancer survivorshiplate effects of cancer treatmentlymphedema preventionretinoblastoma treatmentWernicke's encephalopathy

Research Overview

Papers
238
Total Citations
2,443
Papers (5y)
56
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
56total
2022
2023
2024
2025
2026
Citations per year (5y)
303total
20222023202420252026

Selected Papers

15
1
Article|60 citations·2012
The Efficacy of Arm Node Preserving Surgery Using Axillary Reverse Mapping for Preventing Lymphedema in Patients with Breast Cancer
Jung Woo Han, Yu Jeong Seo, Jung Eun Choi, Su Hwan Kang, Young Kyung Bae, Soo Jung Lee
SJR Q2Journal of Breast CancerOA

Arm node preserving was possible in all breast cancer patients with identifiable arm nodes, during ALND or SLNB, except for those with high surgical N stage, and lymphedema did not develop in patients with arm node preserving surgery.

Cancer ResearchBiochemistry, Genetics and Molecular Biology
2
Article|52 citations·2009
Comprehensive clinical follow-up of late effects in childhood cancer survivors shows the need for early and well-timed intervention
Jung Woo Han, Seung Yeon Kwon, S. Won, Yoojin Shin, J. H. Ko, Chuhl Joo Lyu
SJR Q1Annals of OncologyOA
Pediatrics, Perinatology and Child HealthMedicine
3
Article|21 citations·2012
Two Cases of Wernicke's Encephalopathy in Young Age Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation
Jung Woo Han, Seungtaek Lim, Hye Sun Shin, Hyojin Park, Won Jai Jung, Seung Yeon Kwon, Chuhl Joo Lyu
SJR Q2Yonsei Medical JournalOA

Wernicke's encephalopathy is an acute neurolopsychiatric syndrome caused by thiamine deficiency, and classically presents with the triad of opthalmopathy, ataxia and altered mentality. Both prolonged total parenteral nutrition and reduced oral intake can induce Wernicke's encephalopathy during hematopoietic stem cell transplantation (HSCT). Although early treatment is important for recovery from Wernicke's encephalopathy, the vague symptoms and characteristics hinder early diagnosis. Furthermore

NeurologyMedicine
4
Article|20 citations·2015
Poor bone health at the end of puberty in childhood cancer survivors
Jung Woo Han, Hyo Sun Kim, Seung Min Hahn, Song Jin, Yoon Jung Shin, Sun Hee Kim, Yoon Sun Lee, Jin Lee, Chuhl Joo Lyu
SJR Q1Pediatric Blood & CancerOA

Decreased BMD was prevalent in our study cohort. Endocrine dysfunction was found to be a significant risk factor, and it should be managed in survivors to ensure future bone health.

Pediatrics, Perinatology and Child HealthMedicine
5
Article|18 citations·2016
Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice
Jung Woo Han, Young‐Ho Lee, Su-In Yoen, Joel Abramowitz, Lutz Birnbaumer, Min Goo Lee, Joo Young Kim
SJR Q1Molecular and Cellular BiochemistryOA
Cardiology and Cardiovascular MedicineMedicine
6
Article|14 citations·2014
Short-term effects of topical cyclosporine A 0.05% (Restasis) in long-standing prosthetic eye wearers: a pilot study
Jung Woo Han, Jin Sook Yoon, Sun Young Jang
SJR Q1EyeOA
Public Health, Environmental and Occupational HealthMedicine
7
Article|13 citations·2020
Isoproterenol-induced hypertrophy of neonatal cardiac myocytes and H9c2 cell is dependent on TRPC3-regulated CaV1.2 expression
Jung Woo Han, Choeun Kang, Yonjung Kim, Min Goo Lee, Joo Young Kim
SJR Q1Cell CalciumOA
Cardiology and Cardiovascular MedicineMedicine
8
Article|10 citations·2013
Increasing and Worsening Late Effects in Childhood Cancer Survivors during Follow-up
Jung Woo Han, Hyo Sun Kim, Beom Sik Kim, Seung Yeon Kwon, Yoon Jung Shin, Sun Hee Kim, Jong Hee Ko, Chuhl Joo Lyu
SJR Q2Journal of Korean Medical ScienceOA

Recent advances in childhood cancer treatment have increased survival rates to 80%. Two out of three survivors experience late effects (LEs). From a group of 241 survivors previously described, 193 were followed at the long-term follow-up clinic (LTFC) of Severance Hospital in Korea; the presence of LEs was confirmed by oncologists. We reported the change in LEs during 3 yr of follow-up. The median follow-up from diagnosis was 10.4 yr (5.1-26.2 yr). Among 193 survivors, the percentage of patient

Pediatrics, Perinatology and Child HealthMedicine
9
Article|10 citations·2016
Favorable outcome of alternate systemic and intra-arterial chemotherapy for retinoblastoma
Seung Min Hahn, Hyo Sun Kim, Dong Joon Kim, Sung Chul Lee, Chuhl Joo Lyu, Jung Woo Han
SJR Q3Pediatric Hematology and OncologyOA

The recent trend of treatment for retinoblastoma is to salvage the eye globes as well as achieving patients' survival. Intra-arterial chemotherapy (IAC) is one of the current standard treatment; however, it cannot exclude the risk of occult micrometastases in the central nervous system in advanced-stage retinoblastoma. Alternate fashion of intravenous chemotherapy (IVC) and IAC strategy was developed to increase the eye salvage rate and to reduce the metastatic risk. Between January 2012 and Dec

OphthalmologyMedicine
10
Article|9 citations·2013
Increasing and Worsening Late Effects in Childhood Cancer Survivors during Follow-up
한정우, 김효선, 김범식, 권승연, 신윤정, 김선희, 유철주, 고종희
Journal of Korean Medical Science

Recent advances in childhood cancer treatment have increased survival rates to 80%. Two out of three survivors experience late effects (LEs). From a group of 241 survivors previously described, 193 were followed at the long-term follow-up clinic (LTFC) of Severance Hospital in Korea; the presence of LEs was confirmed by oncologists. We reported the change in LEs during 3 yr of follow-up. The median follow-up from diagnosis was 10.4 yr (5.1-26.2 yr). Among 193 survivors, the percentage of patient

11
Article|7 citations·2018
Comparison of the neuroinflammatory responses to selective retina therapy and continuous-wave laser photocoagulation in mouse eyes
Jung Woo Han, Juhye Choi, Young S. Kim, Jina Kim, Ralf Brinkmann, Jungmook Lyu, Tae Kwann Park
SJR Q1Graefe s Archive for Clinical and Experimental Ophthalmology
OphthalmologyMedicine
12
Article|6 citations·2022
The Efficacy of Alternate Systemic Intravenous Chemotherapy and Intra-arterial Chemotherapy Approach for Eye Globe Salvage in Retinoblastoma
Jung Woo Han, Christopher Seungkyu Lee, Seung Min Hahn, Won Kee Ahn, Hyo Sun Kim, Hyeseon Yun, Sung Chul Lee, Byung Moon Kim, Dong Joon Kim, Chuhl Joo Lyu
SJR Q1Cancer Research and TreatmentOA

PURPOSE: The advances in the treatment of retinoblastoma have enabled salvaging the globe in advanced stages with intra-arterial chemotherapy (IAC). We developed a strategy of alternate application of systemic intravenous chemotherapy (IVC) and IAC (referred to as alternate systemic IVC and IAC; ASIAC) to reduce central nervous metastases during IAC and examined its efficacy and safety in eye globe salvage in this study. MATERIALS AND METHODS: Between January 2010 and February 2021, 43 eyes of 4

OphthalmologyMedicine
13
letter|6 citations·2015
Huge retroperitoneal complicated pseudotumour in haemophilia B with inhibitor
Susanne Hahn, Seung Min Hahn, Song Jin, H. S. Kim, Chuhl Joo Lyu, J. G. Lee, Jung Woo Han
SJR Q1Haemophilia
HematologyMedicine
14
Article|5 citations·2016
Current Trends in Management for Central Nervous System Germ Cell Tumor
Jung Woo Han, Kyung‐Nam Koh, Ji Yoon Kim, Hee Jo Baek, Ji Won Lee, Kyu‐Won Shim, Jaeho Cho, Dong-Seok Kim
Imsang soa hyeoraek jong-yang/Imsang soa hyeol'aeg jong'yang/Clinical pediatric hematology-oncologyOA

Central nervous system germ cell tumor is a rare but important tumor in childhood brain tumors. It requires a multidisciplinary approach to increase survival and promote quality of life, and all three treatment modalities including surgery, radiotherapy and chemo-therapy has its own distinct role for germ cell tumor. For germinoma, radiotherapy alone can cure the disease but, the effort to limit the long term toxicity and the proper combi-nation of chemotherapy and radiotherapy are under investi

GeneticsMedicine
15
Article|4 citations·2022
Factors influencing perceived communication quality for successful fertility preservation counseling for adolescent and young adult cancer patients and their caregivers in Korea
Yoo Sub Shin, Mina Park, Bo Hyon Yun, Seung Min Hahn, Seung Yeon Kwon, Won Kee Ahn, Chuhl Joo Lyu, Jung Woo Han
SJR Q1Supportive Care in CancerOA
Public Health, Environmental and Occupational HealthMedicine

Research Areas

GeneticsHematologyPediatrics, Perinatology and Child HealthPulmonary and Respiratory MedicineMolecular BiologyOphthalmology

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