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Ji Hyun Jo

Korea University · 医学

研究室紹介

Professor Ji Hyun Jo's research lab focuses on translational biomedical research with a strong emphasis on clinical biomarkers and their applications in oncology and hematology. The lab investigates novel diagnostic markers such as tumor M2-PK and neutrophil gelatinase-associated lipocalin (NGAL) to improve early detection and monitoring of gastrointestinal and hematologic malignancies. Additionally, the lab explores the impact of medical interventions—such as irradiation on blood products—on cellular components like microparticles, contributing to transfusion safety. The integration of clinical diagnostics with molecular mechanisms defines the lab’s interdisciplinary approach.

biomarkerscolorectal cancerhematologic malignanciesmicroparticlesNGAL

Research Overview

Papers
71
Total Citations
713
Papers (5y)
8
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
8total
2022
2023
2024
2025
2026
Citations per year (5y)
8total
20222023202420252026

Selected Papers

15
1
Article|62 citations·2012
Evaluation of five rapid diagnostic kits for influenza A/B virus
Chi Hyun Cho, Mi Kyung Woo, Ju Yeon Kim, Seok Cheong, Chang‐Kyu Lee, Seong-Soo A. An, Chae Seung Lim, Woo Joo Kim
SJR Q3Journal of Virological Methods
EpidemiologyMedicine
2
Article|48 citations·2013
Evaluation of a novel real-time RT-PCR using TOCE technology compared with culture and Seeplex RV15 for simultaneous detection of respiratory viruses
Chi Hyun Cho, Bayarjavkhlan Chulten, Chang Kyu Lee, Myung‐Hyun Nam, Soo Young Yoon, Chae Seung Lim, Yunjung Cho, Young Kee Kim
SJR Q1Journal of Clinical VirologyOA
EpidemiologyMedicine
3
Article|39 citations·2014
Evaluation of the AdvanSure™ real-time RT-PCR compared with culture and Seeplex RV15 for simultaneous detection of respiratory viruses
Chi Hyun Cho, Chang Kyu Lee, Myung‐Hyun Nam, Soo-Young Yoon, Chae Seung Lim, Yunjung Cho, Young Kee Kim
SJR Q2Diagnostic Microbiology and Infectious DiseaseOA
EpidemiologyMedicine
4
Article|11 citations·2016
Evaluation of the Performance of a Fecal Tumor M2-PK Rapid Kit Using Stool Specimens for Detection of Colorectal Tumors.
Chi Hyun Cho, Jeeyong Kim, Mi‐Ae Jang, Beom Jae Lee, Jong Jae Park, Chae Seung Lim
PubMed

BACKGROUND: In gastrointestinal tumors, only subunits of pyruvate kinase isoenzyme type M2 are detectable, and mainly in the dimeric form termed tumor M2-PK. A rapid test for the detection of M2-PK in stool has been developed. We evaluated the performance of the M2-PK rapid kit for the detection of colorectal tumors compared with colonoscopy DESIGN: Stool specimens (n=268) were obtained from patients who had a fecal occult blood test and colonoscopy performed for clinical evaluation or routine h

Pathology and Forensic MedicineMedicine
5
Article|10 citations·2008
Mobile multi-hop relay system using AMC for multicast broadcast service over mobile WiMAX
Chi Hyun Cho, Kyung Tae Kim, Hee Yong Youn
Wireless Telecommunications Symposium

Mobile WiMAX based on IEEE802.16e standard supports various kinds of broadband data services such as VOD, VoIP, and MBS (multicast broadcast service). Unlike wired networks, however, wireless networks have limited bandwidth. MBS overcomes this problem using a shared downlink channel for efficiently supporting a number of users. However, its coverage and throughput are significantly affected by the operational condition. In this paper we propose to employ mobile multi-hop relay (MMR) along with a

Electrical and Electronic EngineeringEngineering
6
Article|6 citations·2016
Effect of Irradiation on Microparticles in Red Blood Cell Concentrates
Chi Hyun Cho, Seung Gyu Yun, Young Eun Koh, Chae Seung Lim
SJR Q2Annals of Laboratory MedicineOA

Changes in microparticles (MP) from red blood cell (RBC) concentrates in the context of irradiation have not been investigated. The aim of this study was to evaluate how irradiation affects the number of MPs within transfusion components. Twenty RBC concentrates, within 14 days after donation, were exposed to gamma rays (dose rate: 25 cGy) from a cesium-137 irradiator. Flow cytometry was used to determine the numbers of MPs derived from RBC concentrates before and 24 hr after irradiation. The me

HematologyMedicine
7
Article|6 citations·2009
An Effective Batching Scheme Utilizing the Segment Interval Time for Wireless IPTV
Chi Hyun Cho, Kyung Tae Kim, Hee Yong Youn, Sung Oh Hwang

The demand on IPTV services has been greatly increasing in the area of wireless communication. For supporting a large number of users with limited resources, the development of effective transmission technology is inevitable. In this paper we propose an efficient batching scheme enhancing the performance of VoD system over wireless IPTV. The proposed approach capitalizes the notion of segment interval time to maximize the channel utilization. Computer simulation shows that the proposed approach

Computer Networks and CommunicationsComputer Science
8
Article|6 citations·2015
Effect of Interleukin-29 on Interferon-α Secretion by Peripheral Blood Mononuclear Cells.
Chi Hyun Cho, Soo Young Yoon, Chang Kyu Lee, Chae Seung Lim, Yunjung Cho
PubMedOA

OBJECTIVE: The effect of interleukin (IL)-29, a new therapeutic agent similar to type I interferons (IFNs), on IFN-α secretion of human plasmacytoid dendritic cells (pDCs) has not been studied. Therefore, in this study, we aimed to clarify the effect of IL-29 on IFN-α secretion of pDCs using human peripheral blood mononuclear cells (PBMCs) in the presence of cytosine-phosphate-guanosinemotif-containing oligodeoxy nucleotides (CpG). MATERIALS AND METHODS: In this experimental and prospective stud

ImmunologyImmunology and Microbiology
9
Article|6 citations·2020
Analysis of bone marrow supernatant neutrophil gelatinase‐associated lipocalin and hematological parameters in hematological malignancy
Chi Hyun Cho, Jaehyung Cha, Eun‐Ah Chang, Myung‐Hyun Nam, Seo‐Jin Park, Hwa Jung Sung, Se Ryeon Lee
SJR Q1Journal of Clinical Laboratory AnalysisOA

BACKGROUND: Neutrophil gelatinase-associated lipocalin (NGAL) is a urine biomarker related to acute renal injury. Whereas several studies have evaluated NGAL levels in hematological malignancy, using peripheral blood (PB). Recently, bone marrow (BM) NGAL level was reported to be higher than PB NGAL level in individuals with hematological malignancy, suggesting that BM NGAL would reflect BM microenvironment better than PB NGAL. We measured BM NGAL levels in patients with hematological malignancy,

NephrologyMedicine
10
Article|6 citations·2019
Association of peripheral blood neutrophil gelatinase‐associated lipocalin levels with bone marrow neutrophil gelatinase‐associated lipocalin levels and neutrophil count in hematologic malignancy
Chi Hyun Cho, Jung Hee Yoon, Deok‐Su Kim, Shin‐Jong Kim, Hwa Jung Sung, Se Ryeon Lee
SJR Q1Journal of Clinical Laboratory AnalysisOA

Abstract Background Although neutrophil gelatinase‐associated lipocalin (NGAL) is a biomarker for acute kidney injury, recently, high NGAL levels have been reported in hematologic malignancies. Given the mechanism underlying NGAL synthesis and secretion in neutrophilic series, it is speculated that NGAL levels are higher in bone marrow (BM) than in peripheral blood (PB). Additionally, PB NGAL levels are thought to be associated with neutrophilic parameters. We aimed to test both hypotheses in he

NephrologyMedicine
11
Article|5 citations·2015
A case report of a fetus with mosaic autosomal variegated aneuploidies and literature review.
Chi Hyun Cho, Min‐Jeong Oh, Chae Seung Lim, Chang Kyu Lee, Yunjung Cho, Soo-Young Yoon
PubMed

Mosaic variegated aneuploidy (MVA) is a recessive condition characterized by mosaic aneuploidies, predominantly trisomies and monosomies, involving multiple chromosomes and tissues. The phenotype of MVA syndrome includes severe microcephaly and growth deficiency, central nervous system anomalies, mental retardation, mild physical anomalies, and predisposition to cancer. We report a case of true fetal mosaicism for variegated aneuploidies detected in amniotic fluid cells. A 33-year-old primigravi

Pediatrics, Perinatology and Child HealthMedicine
12
Article|5 citations·2017
Relationship Linking Dietary Quercetin and Roughage to Concentrate Ratio in Feed Utilization, Ruminal Fermentation Traits and Immune Responses in Korean Indigenous Goats
Chi Hyun Cho, Byung Mo Yang, No Seong Park, Hyung Suk Lee, Minho Song, Young‐Joo Yi, Jung Min Heo, Samiru Sudharaka Wickramasuriya, Hyun Min Cho, Soo Kee Lee
Han-guk choji josaryo hakoeji
Food ScienceAgricultural and Biological Sciences
13
Article|4 citations·2011
ABO 동종 응집소 역가 측정을 위한 시험관 및 미세원주응집법의 평가
조치현, 김하늬, 윤승규, 최계령, 최재열, 김장수, 임채승, 김영기, 이갑노

Background: ABO antibody titration is useful for the evaluation of ABO-incompatible bone marrow or solid organ transplantations, yet the results quite vary between different test methods used. We compared the results of microcolumn agglutination and tube methods. Methods: Anti-A and anti-B isoagglutionin titers were determined in 63 healthy individuals (23 O, 20 A, and 20 B blood groups) using 4 different methods: immediate spin tube (tube), microcolumn agglutination without anti-human globulin

14
Article|3 citations·2015
A Case of Diabetic Mellitus Foot Infection by a Newly Reported Neisseria Skkuensis: Case Report.
Chi Hyun Cho, Chang Kyu Lee, Myung‐Hyun Nam, Soo‐Young Yoon, Chae Seung Lim, Yunjung Cho, Young Kee Kim
PubMed

In pus and wound samples collected from the right second toe of a 61-year-old woman with diabetes mellitus (DM), gram-negative diplococci bacterium was observed. However, the bacterium could not be identified by conventional microbiological methods and mass spectrometry. In the partial 16S rRNA gene sequence analysis, the bacterium showed a 100% identity match with GenBank sequence FJ0763637.1 (Neisseria skkuensis). N. skkuensis, SMC-A9199 strain, was reported as a novel species in 2010 based on

EpidemiologyMedicine
15
Article|3 citations·2024
Novel approach exploring the correlation between presepsin and routine laboratory parameters using explainable artificial intelligence
Jae‐Seung Jeong, Takho Kang, Hyunsu Ju, Chi Hyun Cho
SJR Q1HeliyonOA

Although presepsin, a crucial biomarker for the diagnosis and management of sepsis, has gained prominence in contemporary medical research, its relationship with routine laboratory parameters, including demographic data and hospital blood test data, remains underexplored. This study integrates machine learning with explainable artificial intelligence (XAI) to provide insights into the relationship between presepsin and these parameters. Advanced machine learning classifiers provide a multilatera

EpidemiologyMedicine

Research Areas

EpidemiologyHematologyPublic Health, Environmental and Occupational HealthNephrologyPathology and Forensic MedicineFood Science

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