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Ji-seon Chae

Ewha Womans University · 医学

研究室紹介

Professor Ji-seon Chae's research lab specializes in clinical anesthesiology and pain management, with a strong focus on optimizing perioperative care and developing novel interventions for neuropathic pain conditions. The lab investigates the hemodynamic assessment using point-of-care ultrasound, evaluates anesthetic agents for neuroprotection in neurosurgical patients, and explores innovative therapeutic strategies such as exosome-based treatments for chronic pain syndromes like complex regional pain syndrome (CRPS). A key direction involves translational research, bridging preclinical models with clinical applications to improve patient outcomes in postoperative and chronic pain management.

anesthesiapoint-of-care ultrasoundchronic painexosome therapyperioperative management

Research Overview

Papers
29
Total Citations
160
Papers (5y)
15
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
15total
2021
2022
2023
2024
2026
Citations per year (5y)
73total
20212022202320242026

Selected Papers

15
1
Article|35 citations·2020
Pre-anaesthesia ultrasonography of the subclavian/infraclavicular axillary vein for predicting hypotension after inducing general anaesthesia
Min Hee Choi, Ji Seon Chae, Hyun Jung Lee, Jae Hee Woo
SJR Q1European Journal of Anaesthesiology

BACKGROUND: Bedside sonography of the inferior vena cava has been demonstrated to be a reliable tool for assessing intravascular volume status. Subclavian vein (SCV) assessment was proposed as a reasonable adjunct for measuring the inferior vena cava. OBJECTIVE: We examined whether the preoperative diameter and collapsibility index of the SCV or the infraclavicular axillary vein could predict the incidence of hypotension after induction of general anaesthesia in patients undergoing laparoscopic

SurgeryMedicine
2
Article|21 citations·2023
Intravenous Versus Perineural Dexamethasone for Reducing Rebound Pain After Interscalene Brachial Plexus Block: A Randomized Controlled Trial
Hyun Jung Lee, Jae Hee Woo, Ji Seon Chae, Youn Jin Kim, Sang-Jin Shin
SJR Q2Journal of Korean Medical ScienceOA

Background: Interscalene brachial plexus block (ISB) is a common regional technique to manage acute postoperative pain for arthroscopic rotator cuff tear repair.However, rebound pain may compromise its overall benefit.Our aim was to investigate the primary hypothesis that perineural and intravenous dexamethasone have different effects on rebound pain after resolution of ISB for arthroscopic rotator cuff tear repair.Methods: Patients aged 20 years scheduled for elective arthroscopic rotator cuff

SurgeryMedicine
3
Article|19 citations·2018
The effect of anesthetic agents on cerebral vasospasms after subarachnoid hemorrhage
Jong Wha Lee, Jae Hee Woo, Hee Jung Baik, Dong Yeon Kim, Ji Seon Chae, Na Yang, Eui Kyo Seo
SJR Q3MedicineOA

Cerebral vasospasm is the most important cause of morbidity after an aneurysm clipping in the early postoperative period. The aim of this retrospective study was to evaluate whether the incidence of vasospasms differs when using propofol or desflurane for an emergent aneurysm clipping.The data from 102 patients (50 in the propofol group, 52 in the desflurane group) were analyzed. The occurrence of vasospasm based on daily transcranial Doppler, angiography, and cerebral infarction during 14 days

NeurologyMedicine
4
Article|11 citations·2023
The Effect of Super-Repressor IkB-Loaded Exosomes (Exo-srIκBs) in Chronic Post-Ischemia Pain (CPIP) Models
Ji Seon Chae, Hyun‐Ju Park, So‐Hee Ahn, Eun‐Chong Han, Yoonjin Lee, Youn Jin Kim, Eun Jin Ahn, Hye‐Won Oh, Hyun Jung Lee, Chulhee Choi, Youn-Hee Choi, Wonjoong Kim
SJR Q1PharmaceuticsOA

Complex regional pain syndrome (CRPS) is a condition associated with neuropathic pain that causes significant impairment of daily activities and functioning. Nuclear factor kappa B (NFκB) is thought to play an important role in the mechanism of CRPS. Recently, exosomes loaded with super-repressor inhibitory kappa B (Exo-srIκB, IκB; inhibitor of NFκB) have been shown to have potential anti-inflammatory effects in various inflammatory disease models. We investigated the therapeutic effect of Exo-s

PhysiologyMedicine
5
Article|10 citations·2007
외래 간호인력 업무활동 수행도와 중요도 분석- 종합병원.종합전문요양기관 중심으로 -
황혜영, 김문실, 정문영, 박정혜, 김지수, 전인숙, 배경옥, 서미숙, 양우정, 채지선, 홍지연

Purpose: This study focused on analysing the performance and the perception of importance about workload of ambulatory nurses and nurse-aides for quality of nursing. Method: The subjects of this study were 126 ambulatory nurses and 117 nurse-aides in 6 secondary and 4 tertiary hospitals. The method of data collection was used the questionnaire. Result: As a result, First, nurses' activities that the performance score is above 3.0 are reception, guidance, reservation, confirm, checking medical re

6
Article|10 citations·2022
Effects of Local Anesthetics With or Without Steroids in High-Volume Transforaminal Epidural Blocks for Lumbar Disc Herniation: A Randomized, Double-Blind, Controlled Trial
Ji Seon Chae, Wonjoong Kim, Se Hee Choi
SJR Q2Journal of Korean Medical ScienceOA

BACKGROUND: Lumbar transforaminal epidural block (TFEB) is an effective treatment modality for radicular pain due to lumbar disc herniation (LDH). The addition of steroids is more effective than local anesthetic alone in TFEBs for patients with LDH. Moreover, the efficacy of TFEBs has been reported to be positively correlated with the volume of injectate. We hypothesized that high-volume TFEBs without steroids effectively alleviate axial back and radicular pain associated with LDH. This study co

Pathology and Forensic MedicineMedicine
7
Article|8 citations·2018
Compression stockings reduce the incidence of hypotension but not that of cerebral desaturation events in the beach-chair position: a randomized controlled trial
Jae Hee Woo, Youn Jin Kim, Ji-sun Jeong, Ji Seon Chae, Young Rong Lee, Jin Young Chon
SJR Q1Korean journal of anesthesiologyOA

Thigh-high compression stockings reduced the incidence of hypotension but not that of CDEs. Our results suggest that other factors, beyond hypotension itself, contribute to CDEs and in other words, efforts just to reduce the incidence of hypotension may not mainly contribute to a reduction of CDEs occurrence in the BCP under general anesthesia.

SurgeryMedicine
8
Article|6 citations·2018
Lead fracture of peripheral nerve stimulator for brachial plexopathy -a case report-
S. Choi, Ji Seon Chae, Youn Jin Kim, Jin Young Chon, Ho Sik Moon
SJR Q1Korean journal of anesthesiologyOA

Peripheral nerve stimulation (PNS) is a useful treatment for chronic pain, but it can cause damage depending on its application site. Here, we describe the case of a 54-year-old man who underwent PNS for brachial plexopathy in 2015. One lead was implanted on the left medial cord to stimulate the medial antebrachial cutaneous nerve, and the other was implanted on the radial nerve to stimulate the posterior antebrachial cutaneous nerve. Both leads were inserted near the shoulder joint but did not

Anesthesiology and Pain MedicineMedicine
9
Article|6 citations·2023
Predictability of Radiologically Measured Psoas Muscle Area for Intraoperative Hypotension in Older Adult Patients Undergoing Femur Fracture Surgery
Youn Young Lee, Jae Hee Woo, In‐Young Yoon, Hyun Jung Lee, Sang-Mee Ahn, Ji Seon Chae, Youn Jin Kim
SJR Q1Journal of Clinical MedicineOA

This retrospective study aimed to determine the predictive value of radiologically measured psoas muscle area (PMA) for intraoperative hypotension (IOH) using receiver operating characteristic (ROC) curves in older adult patients with hip fractures. The cross-sectional axial area of the psoas muscle was measured by CT at the level of the 4th lumbar vertebrae and normalized by body surface area (BSA). The modified frailty index (mFI) was used to assess frailty. IOH was defined as an absolute thre

Cardiology and Cardiovascular MedicineMedicine
10
Article|6 citations·2024
HKA-Net: clinically-adapted deep learning for automated measurement of hip-knee-ankle angle on lower limb radiography for knee osteoarthritis assessment
Young-Tak Kim, Beom-Su Han, Jung Bin Kim, K. Jason, Je Hyeong Hong, Yunsik Son, Jae‐Ho Han, Synho Do, Ji Seon Chae, Jung-Kwon Bae
SJR Q1Journal of Orthopaedic Surgery and ResearchOA

BACKGROUND: Accurate measurement of the hip-knee-ankle (HKA) angle is essential for informed clinical decision-making in the management of knee osteoarthritis (OA). Knee OA is commonly associated with varus deformity, where the alignment of the knee shifts medially, leading to increased stress and deterioration of the medial compartment. The HKA angle, which quantifies this alignment, is a critical indicator of the severity of varus deformity and helps guide treatment strategies, including corre

SurgeryMedicine
11
Article|5 citations·2023
Comparison of the Severity of Zoster-Associated Pain and Incidence of Postherpetic Neuralgia in Patients with and without Pre-Existing Spinal Disorders at the Same Spinal Nerve Level: A Retrospective Multicenter Study
Ji Seon Chae, Jiwoong Im, Yong Ju Choi, Hyun Jung Lee, Wonjoong Kim
SJR Q2Journal of Personalized MedicineOA

The incidences of herpes zoster (HZ) and postherpetic neuralgia (PHN) are significantly influenced by age. As individuals age, the occurrence of spinal disorders increases, thereby raising the likelihood of HZ and PHN coexistence. Considering this, our study aimed to explore the potential impact of pre-existing spinal disorders at the nerve level where HZ developed, on the severity of zoster-associated pain (ZAP) and the incidence of PHN. For our investigation, we retrospectively analyzed a tota

EpidemiologyMedicine
12
Article|4 citations·2018
Endotracheal Intubation Using McGrath Videolaryngoscope in Klippel-Feil Syndrome
Ji Seon Chae, Jae Hee Woo, Chi Hyo Kim, Eun Hee Chun, Hee Jung Baik, Min Hee Choi
The Ewha Medical JournalOA

Patients with Klippel-Feil syndrome require much attention during anesthesia because of congenital abnormalities in head and neck regions and the high probability of neurological damage from cervical spine instability during endotracheal intubation. We report a case of successful endotracheal intubation using a videolaryngoscope in a patient with Klippel-Feil syndrome who experienced difficult transnasal intubation.

Anesthesiology and Pain MedicineMedicine
13
Article|4 citations·2023
Efficacy of scrambler therapy in patients with painful diabetic peripheral neuropathy: A single-arm, prospective, pilot study
Seung Hee Yoo, Wonjoong Kim, Ji Seon Chae, Bo Kyung Kang, Min Jeong Kang, Min Hyouk Beak
SJR Q3MedicineOA

BACKGROUND: A variety of medications are available to manage painful diabetic peripheral neuropathy (DPN), but the proper treatment remains challenging. Accordingly, various neuromodulation modalities have been used. However, no prospective clinical trials have evaluated the use of scrambler therapy (ST) in painful DPN. This study aimed to explore the long-term effects of ST in managing painful DPN. METHODS: The patients received 10 consecutive STs of 45 minutes every 1 to 2 days. The primary ou

OncologyMedicine
14
Article|3 citations·2018
A retrospective analysis of neurological complications after ultrasound guided interscalene block for arthroscopic shoulder surgery
Ji Sun Jeong, Youn Jin Kim, Jae-Hee Woo, Chi Hyo Kim, Ji Seon Chae
SJR Q2Anesthesia and Pain MedicineOA

Background: Ultrasound-guided interscalene brachial plexus block (US-ISB) has been reported to be effective postoperative analgesia for arthroscopic shoulder surgery. Although considered rare, various neurological complications have been reported. We retrospectively evaluated 668 patients for post operation neurological symptoms including hemidiaphragmatic paresis and post-operative neurologic symptoms after US-ISB.

SurgeryMedicine
15
Article|3 citations·2024
Association of Psoas: Lumbar Vertebral Index (PLVI) with Postherpetic Neuralgia in Patients Aged 60 and Older with Herpes Zoster
Sang-Mee An, Ji Seon Chae, Hyun Jung Lee, Sooyoung Cho, Jiwoong Im
SJR Q1Journal of Clinical MedicineOA

Background/Objectives: The psoas: lumbar vertebral index (PLVI) is a simple and convenient measure to assess central sarcopenia. Recent studies have utilized the psoas area to indirectly assess sarcopenia and frailty, exploring their associations with various health outcomes. This study aims to investigate the relationship between the PLVI and postherpetic neuralgia (PHN) in patients aged 60 years and above following a herpes zoster (HZ) infection. Methods: We conducted a retrospective analysis

EpidemiologyMedicine

Research Areas

SurgeryNeurologyPathology and Forensic MedicineAnesthesiology and Pain MedicineCardiology and Cardiovascular MedicineEpidemiology

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