Skip to main content

Ji Seon Song

Yonsei University · 医学

研究室紹介

Professor Ji Seon Song's research lab focuses on regenerative medicine and biomaterials, with a strong emphasis on mesenchymal stem cells (MSCs) derived from human tonsillar tissue. The lab investigates the biological characteristics, differentiation potential, and clinical applicability of tonsil-derived MSCs, particularly in relation to donor age, long-term culture, and cryopreservation. Additionally, the lab explores tissue engineering strategies using biodegradable scaffolds, such as PLGA/CaP composites, to modulate foreign body giant cell responses and improve implant integration. The research also extends to infectious diseases, including rare fungal and algal infections like protothecosis, and molecular mechanisms in cancer, particularly angiogenesis in renal cell carcinoma.

mesenchymal stem cellsbiomaterialstissue engineeringangiogenesisregenerative medicine

Research Overview

Papers
51
Total Citations
400
Papers (5y)
10
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
10total
2019
2020
2022
2023
2025
Citations per year (5y)
27total
20192020202220232025

Selected Papers

15
1
Article|74 citations·2015
Effects of Donor Age, Long-Term Passage Culture, and Cryopreservation on Tonsil-Derived Mesenchymal Stem Cells
Jin-Sik Choi, Byung‐Joo Lee, Hee‐Young Park, Ji-Sun Song, Sung‐Chan Shin, Jin‐Choon Lee, Soo‐Geun Wang, Jin Sup Jung
SJR Q2Cellular Physiology and BiochemistryOA

OBJECTIVES: Human mesenchymal stem cells (MSCs) are efficacious in various cellular therapeutic applications and have been isolated from several tissues. Recent studies have reported that human tonsil tissue contains a new source of progenitor cells, potentially applicable for cell-based therapies. Information about the effects of donor age, long-term passage and cryopreservation are essential for clinical applications and cell-based therapies. Therefore, the authors investigated how the morphol

GeneticsMedicine
2
Article|51 citations·2002
Prognostic value of vascular endothelial growth factor in Stage IB carcinoma of the uterine cervix
Ik Jae Lee, Kyung‐Ran Park, Kang-Kyoo Lee, Ji-Sun Song, Kwang-Gil Lee, Jong‐Young Lee, Dong-Soo Cha, Hyun-Il Choi, Dong-Hee Kim, Young‐Kun Deung
SJR Q1International Journal of Radiation Oncology*Biology*PhysicsOA
Obstetrics and GynecologyMedicine
3
Article|29 citations·2004
An in-vivo model to interrogate the transition from acute to chronic inflammation
David Lickorish, Jerry Kok Yen Chan, Ji-Sun Song, JE Davies
SJR Q2European Cells and MaterialsOA

This study describes the modulation of the rodent foreign body giant cell (FBGC) response to subcutaneously implanted, biodegradable poly(lactide-co-glycolide)/calcium phosphate (PLGA/CaP) composites by application of a thin surface coat of calcium phosphate. Macroporous PLGA/CaP composite scaffolds, with interconnecting macroporosity, were half coated with a 3mm thick layer of CaP by immersion in simulated body fluid. Half-coated scaffolds were implanted subcutaneously in the dorsum of male Wis

Biomedical EngineeringEngineering
4
Article|27 citations·2013
Human Cutaneous Protothecosis: Report of a Case and Literature Review
Jae Yeon Seok, Yoon-Ho Lee, Hyukmin Lee, Sang Yeop Yi, Hwa Eun Oh, Ji-Sun Song
The Korean Journal of PathologyOA

The Prototheca species is achlorophyllic algae and rarely causes human infection. Human protothecosis presents clinically as a cutaneous infection, olecranon bursitis, and disseminated systemic disease. We report a case of human cutaneous protothecosis involving the left wrist. A 68-year-old man presented with an ill-defined erythematous lesion with crust at the dorsal aspect of his left wrist. A punch biopsy was performed to reveal the histologic features of granulomatous inflammation with necr

Agronomy and Crop ScienceAgricultural and Biological Sciences
5
Article|22 citations·2001
Vascular Endothelial Growth Factor - Its Relation to Neovascular ization and Their Significance as Prognostic Factors in Renal Cell Carcinoma
Ki Hak Song, Ji-Sun Song, Goo‐Bo Jeong, Jung Min Kim, Soon Hee Jung, Jaemann Song
SJR Q2Yonsei Medical JournalOA

Angiogenesis is a series of processes that include endothelial proliferation, migration and tube formation. Vascular endothelial growth factor (VEGF) is regarded as a potent mediator of angiogenesis, vascular permeability and tumor cell growth in renal cell carcinoma. This study was designed to evaluate the expression of VEGF and the microvessel count (MVC) and to determine their prediction efficacies for prognosis in renal cell carcinoma. The relationship between the expression of VEGF and MVC

Pulmonary and Respiratory MedicineMedicine
6
Article|21 citations·1998
Authenticated key exchange protocols resistant to password guessing attacks
Taekyoung Kwon, Ji-Sun Song
IEE Proceedings - Communications

A user-chosen password is not appropriate for a shared secret by which an authenticated key exchange protocol is operated. This is because users choose their passwords so that they can be easily memorised and can be typed using an alphabetic keyboard or a numeric keypad. Therefore, the password becomes a weak secret which is vulnerable to guessing attacks. However, users prefer to utilise the short easily memorised passwords. Several protocols, which are resistant to guessing attacks, have been

Information SystemsComputer Science
7
Article|18 citations·2016
Isolation and Localization of Mesenchymal Stem Cells in Human Palatine Tonsil by W5C5 (SUSD2)
Byung‐Joo Lee, Dae‐Woon Kang, Hee‐Young Park, Ji-Sun Song, Jimin Kim, Jeon-Yeob Jang, Jin‐Choon Lee, Soo-Geun Wang, Jin Sup Jung, Sung‐Chan Shin
SJR Q2Cellular Physiology and BiochemistryOA

BACKGROUND/AIMS: Although tonsil-mesenchymal stem cells (T-MSCs) have been studied as a new autologous or homologous source of MSCs, research on specific markers of MSCs and localization for purified T-MSC isolation has not yet been reported. This study investigates the expression of W5C5 (SUSD2) in tonsil stromal cells and the colony-forming ability and differentiation potential of W5C5+ cells to determine the usefulness of W5C5+ MSCs as a marker that can be used for the purification of T-MSCs.

GeneticsMedicine
8
Article|17 citations·2006
Diagnostic Yield of Advanced Colorectal Neoplasia at Colonoscopy, According to Indications: An Investigation from the Korean Association for the Study of Intestinal Diseases (KASID)
Dong Il Park, Young-Wook Kim, Hyeon Chang Kim, Won Ho Kim, Tae Il Kim, Hyunkyu Kim, Stone Yang, Jeong‐Sik Byeon, Moo Hyun Lee, In Sub Jung, Man Ki Chung, Sung-Ae Jung
SJR Q1EndoscopyOA

Age, gender, and referral for colonoscopy from primary care physician constituted important independent predictors of advanced CRN in patients undergoing colonoscopy.

OncologyMedicine
9
Article|16 citations·2001
Agrobacterium-mediated transformation of Campanula glomerata
Young Hee Joung, Mark S. Roh, Kathryn Kamo, Ji-Sun Song
SJR Q1Plant Cell Reports
Molecular BiologyBiochemistry, Genetics and Molecular Biology
10
Article|16 citations·1997
Enhancement in the Effective Thermal Conductivity in Rat Spinotrapezius Due to Vasoregulation
Ji-Sun Song, Lisa X. Xu, Daniel E. Lemons, Sheldon Weinbaum
SJR Q3Journal of Biomechanical Engineering

This study was undertaken to gain a better understanding of the countercurrent heat exchange of thermally significant blood vessels in skeletal muscle by measuring the vascular structure and flow in an exteriorized rat spinotrapezius muscle and estimating the enhancement in the effective thermal conductivity of the muscle. Detailed anatomic measurements of the number density and length of countercurrent vessel pairs between 45 and 165 microns diameter were obtained. Moreover, diameter and blood

PhysiologyMedicine
11
Article|14 citations·2019
Comparison of Radiological and Histological Findings of Lung Parenchyma in Patients with Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
Hee-Jin Park, Seung Min Jung, Jason Jungsik Song, Yong‐Beom Park, Ji-Sun Song, Sang‐Won Lee
SJR Q2Yonsei Medical JournalOA

When lung involvement of AAV is suspected on chest CT, lung biopsy should be recommended for the proper classification of AAV, due to the discordance rate between radiological and histological findings in MPA and EGPA patients, but not GPA patients.

Pulmonary and Respiratory MedicineMedicine
12
Article|12 citations·2017
The functional relevance of diffusion tensor imaging in comparison to conventional MRI in patients with cervical compressive myelopathy
Young-Mi Yang, Woo‐Kyoung Yoo, Je Hyun Yoo, Yoon Hae Kwak, Jae-Keun Oh, Ji-Sun Song, Seok Woo Kim
SJR Q2Skeletal Radiology
SurgeryMedicine
13
Article|12 citations·2019
Bisifusarium Delphinoides, an Emerging Opportunistic Pathogen in a Burn Patient with Diabetes Mellitus
Jihyun Park, Junsang Oh, Ji-Sun Song, Jayoung Kim, Gi‐Ho Sung
SJR Q2MycobiologyOA

An 82-year-old man with diabetes was admitted to the emergency department with a third-degree burn on his left leg. The deep swab specimen from his left leg was cultured on Sabouraud dextrose agar without cycloheximide and incubated at 25 °C for 5 days. On the basis of morphological characteristics and multigene phylogenetic analyses of the internal transcribed spacer region of ribosomal DNA and partial fragments of beta-tubulin and translation elongation factor 1-alpha, the causal agent of fung

Cell BiologyBiochemistry, Genetics and Molecular Biology
14
Article|10 citations·2011
An ectopic hamartomatous thymoma
Dae Bo Shim, Ji-Sun Song, Seung Jae Baek
SJR Q2Auris Nasus Larynx
SurgeryMedicine
15
Article|10 citations·2009
Pigmented Trichoblastoma Arising from the Nevus Sebaceous: A Rare Case in Korea
Han Kyoung Cho, Ji-Sun Song, Won Hyoung Kang, Byung In Ro
SJR Q3Annals of DermatologyOA

Trichoblastoma is occasionally observed in association with a pre-existing nevus sebaceous in the Korean literature. However, there has been no report on the pigmented type. Herein, we report the first Korean case of a pigmented trichoblastoma arising from the nevus sebaceous on the forehead. A 28-year-old male presented with a dark nodular lesion within a yellowish plaque on the forehead. The surrounding yellowish plaque on the forehead had existed since birth. The central, dark-pigmented nodul

GeneticsBiochemistry, Genetics and Molecular Biology

Research Areas

Pulmonary and Respiratory MedicineSurgeryRheumatologyGeneticsBiomedical EngineeringPhysiology

Ji Seon Songの研究をNubintでさらに深く

この研究室の論文をアプリで開き、AIと共に読み、要約し、引用しましょう。