Ji Young Kim

Alzheimer's disease (AD) is an age-related neurodegenerative disease increasingly recognized as one of the most important medical problems affecting the elderly. Although a number of drugs, including several cholinesterase inhibitors and an NMDA receptor antagonist, have been approved for use, they have been shown to produce diverse side effects and yield relatively modest benefits. To overcome these limitations of current therapeutics for AD, extensive research and development are underway to i

그동안 무용교육자의 교수능력과 교수행위에 관한 논의가 많이 이루어져 온 것에비해, 교수자의 신체언어, 외향언어, 청각언어와 같은 비언어적 소통 능력(nonverbal communication)이 학습자의 태도에 영향을 미치는 중요한 교수행동 요소를 밝히는 연구들은 부족했다. 하지만 비언어적 커뮤니케이션이 학생들에게 수업에 대한 이해도와 몰입도를향상시킬 수 있기 때문에(이경탁, 2010, p.125), 효율적인 교수방법과 수업전략을 구사하기위해서는 비언어적 의사소통의 중요성이 강조된다. 따라서 이 연구의 기본 전제는 언어적커뮤니케이션과 비언어적 커뮤니케이션의 어느 한쪽에 비중을 두고 커뮤니케이션의 기능을논쟁하기 보다는, 전달하고자 하는 메시지의 송신과정에서 비언어적 요소들을 중점으로 논의를 하고자 한다. 또한 비언어적 커뮤니케이션을 활용할 때 메시지의 설명력이나 전달력이배가되어 소통을 더욱 극대화시킬 수 있다는 관점에서(이호열, 박재우, 2012 재인용, p.224;Birdwhiste

Abstract. Long-term exposure to particulate matter (PM) with aerodynamic diameters < 10 (PM10) and 2.5 µm (PM2.5) has negative effects on human health. Although station-based PM monitoring has been conducted around the world, it is still challenging to provide spatially continuous PM information for vast areas at high spatial resolution. Satellite-derived aerosol information such as aerosol optical depth (AOD) has been frequently used to investigate ground-level PM concentrations. In this stu

Histone methylation is crucial for transcriptional regulation and chromatin remodeling. It has been suggested that the SET domain containing protein RE-IIBP (interleukin-5 [IL-5] response element II binding protein) may perform a function in the carcinogenesis of certain tumor types, including myeloma. However, the pathogenic role of RE-IIBP in these diseases remains to be clearly elucidated. In this study, we have conducted an investigation into the relationship between the histone-methylating

Cadmium is a well-known carcinogenic and immunotoxic metal commonly found in cigarette smoke and industrial effluent. An altered intracellular calcium ([Ca(2+)](i)) level has been implicated in the pathophysiology of immune dysfunction. The present study was designed to determine the possible involvement of calcium (Ca(2+)) and mitogen-activated protein kinases (MAPKs) signaling pathways on cadmium-induced cell death in J774A.1 murine macrophage cells. Cadmium caused a low-amplitude [Ca(2+)](i)

Recent reports on cocoa are appealing in that a food commonly consumed for pure pleasure might also bring tangible benefits for human health. Cocoa consumption is correlated with reduced health risks of cardiovascular diseases, hypertension, atherosclerosis, and cancer, and the health-promoting effects of cocoa are mediated by cocoa-driven phytochemicals. Cocoa is rich in procyanidins, theobromine, (-)-epicatechin, catechins, and caffeine. Among the phytochemicals present in consumed cocoa, theo

Cells were isolated from four human amniotic membranes, and their biological characteristics analyzed during ex vivo expansion. Morphologically homogenous populations of fibroblast-like cells were obtained from the second or third passage. Under the appropriate culture conditions, these human amniotic membrane-derived mesenchymal cells (HAM) were shown to differentiate into adipocytes, osteocytes, chondrocytes and neuronal cells, as visualized by Oil Red O, von Kossa, alcian blue, anti-Neu N, an

SCOPE: Brain-derived neurotrophic factor (BDNF) is a neurotrophin that supports the survival of existing neurons and encourages the growth and differentiation of new neurons and synapses. We investigated the effect of sulforaphane, a hydrolysis product of glucoraphanin present in Brassica vegetables, on neuronal BDNF expression and its synaptic signaling pathways. METHODS AND RESULTS: Mouse primary cortical neurons and a triple-transgenic mouse model of Alzheimer's disease (3 × Tg-AD) were used