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Jiyeon Kim

Hanyang University · 医学

研究室紹介

Professor Jiyeon Kim's research lab focuses on bioactive compounds from natural sources and their physiological effects, particularly in metabolic and gastrointestinal disorders. The lab investigates the hypoglycemic and insulin-sensitizing properties of plant-derived extracts such as onion peel and mulberry leaf, as well as bioactive molecules like panaxytriol from ginseng, with an emphasis on mechanisms involving cell cycle regulation and metabolic pathways. Additionally, the lab explores the physicochemical properties of modified starches and the rapid detection of foodborne pathogens, reflecting a multidisciplinary approach to functional foods and food safety. The research integrates in vitro, in vivo, and clinical studies to translate natural product findings into health applications.

functional foodsnatural productsmetabolic disordersfoodborne pathogensstarch modification

Research Overview

Papers
421
Total Citations
7,999
Papers (5y)
71
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
71total
2022
2023
2024
2025
2026
Citations per year (5y)
673total
20222023202420252026

Selected Papers

15
1
Article|222 citations·2014
Effect of muscle mass on toxicity and survival in patients with colon cancer undergoing adjuvant chemotherapy
Hee‐Won Jung, Jin Won Kim, Ji Yeon Kim, Sun Wook Kim, Hyun Kyung Yang, Joon Woo Lee, Keun Wook Lee, Duck-Woo Kim, Sung-Bum Kang, Kwang‐Il Kim, Cheol Ho Kim, Jee Hyun Kim
SJR Q1Supportive Care in Cancer
PhysiologyMedicine
2
Article|174 citations·2011
Onion peel extracts ameliorate hyperglycemia and insulin resistance in high fat diet/streptozotocin-induced diabetic rats
Ji Young Jung, Yeni Lim, Min Sun Moon, Ji Yeon Kim, Oran Kwon
SJR Q1Nutrition & MetabolismOA

BACKGROUND: Quercetin derivatives in onions have been regarded as the most important flavonoids to improve diabetic status in cells and animal models. The present study was aimed to examine the hypoglycemic and insulin-sensitizing capacity of onion peel extract (OPE) containing high quercetin in high fat diet/streptozotocin-induced diabetic rats and to elucidate the mechanism of its insulin-sensitizing effect. METHODS: Male Sprague-Dawley rats were fed the AIN-93G diet modified to contain 41.2%

Endocrinology, Diabetes and MetabolismMedicine
3
Review|124 citations·2008
Garlic intake and cancer risk: an analysis using the Food and Drug Administration’s evidence-based review system for the scientific evaluation of health claims
Ji Yeon Kim, Oran Kwon
SJR Q1American Journal of Clinical NutritionOA
Plant ScienceAgricultural and Biological Sciences
4
Article|78 citations·2018
Accuracy of bracket positions with a CAD/CAM indirect bonding system in posterior teeth with different cusp heights
Ji Yeon Kim, Youn-Sic Chun, Minji Kim
SJR Q1American Journal of Orthodontics and Dentofacial Orthopedics
OrthodonticsDentistry
5
Article|76 citations·2011
Diet quality scores and oxidative stress in Korean adults
Ji Yeon Kim, Yoon Jung Yang, YoungSoon Yang, S-Y Oh, Y-C Hong, E. K. Lee, Oran Kwon
SJR Q1European Journal of Clinical Nutrition
Public Health, Environmental and Occupational HealthMedicine
6
Article|75 citations·2018
Antioxidant activity and contents of leaf extracts obtained from Dendropanax morbifera LEV are dependent on the collecting season and extraction conditions
Ji Sun Youn, Young‐Jun Kim, Hye Jin Na, Hae Rim Jung, Chang Khil Song, So Young Kang, Ji Yeon Kim
SJR Q2Food Science and Biotechnology
BiochemistryMedicine
7
Article|67 citations·2014
Mulberry Leaf Extract Improves Postprandial Glucose Response in Prediabetic Subjects: A Randomized, Double-Blind Placebo-Controlled Trial
Ji Yeon Kim, Hyang Mok Ok, Joohee Kim, Seok Won Park, Sung Won Kwon, Oran Kwon
SJR Q3Journal of Medicinal Food

This study was a randomized, double-blind placebo-controlled trial to assess the efficacy of 4 weeks of mulberry leaf aqueous extract (MLAE) supplementation (5 g/day) for postprandial glycemic control in 36 subjects with impaired fasting glucose (IFG) tolerance. Postprandial responses in the glucose, insulin, and C-peptide levels were measured after a carbohydrate load both at baseline and after 4 weeks of MLAE supplementation. The postprandial glycemic response was attenuated in the MLAE group

Endocrinology, Diabetes and MetabolismMedicine
8
Article|57 citations·2013
Acute intake of mulberry leaf aqueous extract affects postprandial glucose response after maltose loading: Randomized double-blind placebo-controlled pilot study
Hye In Chung, Joohee Kim, Joohee Kim, Ji Yeon Kim, Ji Yeon Kim, Oran Kwon
SJR Q1Journal of Functional FoodsOA
Nutrition and DieteticsNursing
9
Article|55 citations·2013
Association of Sleep Dysfunction and Emotional Status With Gastroesophageal Reflux Disease in Korea
Ji Yeon Kim, Nayoung Kim, Pyoung Ju Seo, Jung Won Lee, Min Soo Kim, Sung Eun Kim, So Young Jo, Dong Ho Lee, Hyun Chae Jung
SJR Q1Journal of Neurogastroenterology and MotilityOA

The patients with NERD than ERD suffered more from the symptoms and disturbance in Korea. Sleep dysfunction and anxiety mood were higher and QOL was decreased in GERD, especially in NERD, suggesting that those factors might affect the severity of NERD.

GastroenterologyMedicine
10
Article|55 citations·2002
Inhibitory Effect of Tumor Cell Proliferation and Induction of G2/M Cell Cycle Arrest by Panaxytriol
Ji Yeon Kim, Ki‐Won Lee, Sunho Kim, Jae Joon Wee, Young Suk Kim, Hyong Joo Lee
SJR Q2Planta Medica

Panaxytriol, a polyacetylenic compound, isolated from red ginseng (Panax ginseng C.A. Meyer), was studied to determine its effects on the growth and cell cycle of tumor cell lines. The compound showed both significant cytotoxicity and inhibition of DNA syntheses in various tumor cells tested. For P388D1, a mouse lymphoma cell line, IC50 values for cytotoxicity and inhibition of DNA synthesis were 3.1 and 0.7 microg/ml, respectively. The cytotoxic effect of panaxytriol was both time- and dose-dep

Molecular BiologyBiochemistry, Genetics and Molecular Biology
11
Article|54 citations·2005
Isolation and identification of Escherichia coli O157:H7 using different detection methods and molecular determination by multiplex PCR and RAPD
Ji Yeon Kim, Sohyun Kim, Nam Hoon Kwon, Won Ki Bae, Ji Youn Lim, Hye Cheong Koo, Jun Man Kim, Kyoung Min Noh, Woo Kyung Jung, Kun Taek Park, Yong Ho Park
SJR Q2Journal of Veterinary ScienceOA

Escherichia coli O157:H7 is recognized as a significant food-borne pathogen, so rapid identification is important for food hygiene management and prompt epidemiological investigations. The limited prevalence data on Shiga toxin-producing E. coli (STEC) and E. coli O157:H7 in foods and animals in Korea made an assessment of the risks difficult, and the options for management and control unclear. The prevalence of the organisms was examined by newly developed kit-E. coli O157:H7 Rapid kit. For the

EndocrinologyBiochemistry, Genetics and Molecular Biology
12
Article|54 citations·2017
Structure and digestibility properties of resistant rice starch cross-linked with citric acid
Ji Yeon Kim, Yun-Kyung Lee, Yoon Hyuk Chang
SJR Q1International Journal of Food PropertiesOA

The objective of this present study was to determine the structural, physicochemical, and in-vitro digestibility properties of cross-linked rice starch with citric acid (CARS). Native rice starch (NRS) was cross-linked with different concentrations of citric acid (0, 1, 10, and 30%, w/w) of starch dry basis. The SEM results showed that cross-linking with citric acid induced changes in the morphology of starch granules. Compared with NRS, a new peak at 1734 cm−1 appeared in FT-IR spectra of CARS

Nutrition and DieteticsNursing
13
Article|50 citations·2003
Cell Cycle Dysregulation Induced by Cytoplasm of Lactococcus lactis ssp. lactis in SNUC2A, a Colon Cancer Cell Line
Ji Yeon Kim, Hee Jong Woo, Young Suk Kim, Kyoung Heon Kim, Hyong Joo Lee
SJR Q2Nutrition and Cancer

The anticancer effect of cytoplasmic fraction from Lactococcus lactis ssp. lactis, which had showed strong antiproliferative activity against SNUC2A human colon cancer cell line in the previous study, was investigated. The proliferation of SNUC2A was inhibited by the treatment with cytoplasmic fraction of Lactococcus lactis ssp. lactis in a dose-dependent and partially reversible manner. After exposure to the cytoplasmic fraction of Lc. lactis for 72 h, strong antiproliferative activity was effi

OncologyMedicine
14
Article|50 citations·2002
Screening for antiproliferative effects of cellular components from lactic acid bacteria against human cancer cell lines
Ji Yeon Kim, Hee Jong Woo, Young Suk Kim, Hyong Joo Lee
SJR Q2Biotechnology Letters
Food ScienceAgricultural and Biological Sciences
15
Article|50 citations·2011
Immunogenic proteins of Brucella abortus to minimize cross reactions in brucellosis diagnosis
Kyung Yuk Ko, Jongwan Kim, Moon Her, Sung‐Il Kang, Suk Chan Jung, Dong Hee Cho, Dong Hee Cho, Ji Yeon Kim, Ji Yeon Kim
SJR Q1Veterinary Microbiology
Small AnimalsVeterinary

Research Areas

Molecular BiologyNutrition and DieteticsPharmacologyBiochemistryFood SciencePublic Health, Environmental and Occupational Health

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