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Jong Wook Choi

Hanyang University · 医学

研究室紹介

Professor Jong Wook Choi's research lab focuses on the intersection of metabolic and cardiovascular health, with a strong emphasis on epidemiological and genetic studies in the Korean population. Key research directions include the role of serum albumin and dietary sodium in hypertension and chronic kidney disease, the genetic underpinnings of prediabetes and microvascular complications, and the impact of lifestyle factors on bone mineral density and renal outcomes. The lab leverages large-scale population-based cohorts, such as the Korean Genome and Epidemiology Study (KoGES), to identify biomarkers and genetic risk factors for chronic diseases.

hypertensionchronic kidney diseasegenetic predispositionsodium intakealbumin

Research Overview

Papers
47
Total Citations
261
Papers (5y)
13
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
13total
2021
2022
2023
2024
2025
Citations per year (5y)
85total
20212022202320242025

Selected Papers

15
1
Article|45 citations·2010
Non-synonymous single-nucleotide polymorphisms associated with blood pressure and hypertension
K-W Hong, H-S Jin, J-E Lim, Yun Sang Cho, Min-Jin Go, Jongsun Jung, J-E Lee, Jong Wook Choi, Chol Shin, S-Y Hwang, S-H Lee, H K Park
SJR Q2Journal of Human Hypertension
GeneticsBiochemistry, Genetics and Molecular Biology
2
Article|33 citations·2020
Interactive effect of high sodium intake with increased serum triglycerides on hypertension
Jong Wook Choi, Joon-Sung Park, Chang Hwa Lee
SJR Q1PLoS ONEOA

Our findings suggest that the interaction between a high salt diet and elevated TGs may exert synergistic biological effects on the risk of hypertension.

Nutrition and DieteticsNursing
3
Article|30 citations·2002
Convective Heat Transfer Coefficient for High Pressure Water Jet.
Jong Wook Choi, Jin Won Choi
SJR Q2ISIJ InternationalOA

The scale on the surface of hot rolled steel is removed by high pressure hydraulic descaling in a rolling mill. If the impact pressure of the water jet is higher, the scale is removed well. However, the temperature drop of the hot rolled steel is increased owing to the flow rate of the water jet. On this account, the temperature distribution of the hot rolled steel should be analyzed during the process of the hydraulic descaling. However, the analysis of the temperature distribution is difficult

Ecological ModelingEnvironmental Science
4
Article|20 citations·2021
Genetically determined hypoalbuminemia as a risk factor for hypertension: instrumental variable analysis
Jong Wook Choi, Joon-Sung Park, Chang Hwa Lee
SJR Q1Scientific ReportsOA

Hypoalbuminemia is associated with vascular endothelial dysfunction and the development of chronic cardiovascular diseases. However, the relationship between serum albumin concentration and blood pressure changes remains controversial. Community-based longitudinal cohort data collected from Korean Genome and Epidemiology Study were used in this study. Hypoalbuminemia was defined as a serum albumin concentration of ≤ 4.0 g/dL. A total of 4325 participants were categorized into control (n = 3157)

Cardiology and Cardiovascular MedicineMedicine
5
Article|18 citations·2024
Kidney Health Plan 2033 in Korea: bridging the gap between the present and the future
Do Hyoung Kim, Young Youl Hyun, Jin Joo, Sua Lee, Hyun Kyung Lee, Jong Wook Choi, Su Hyun Kim, Sang Youb Han, Cheol Whee Park, Eun Young Lee, Dae Ryong, Sung Gyun Kim
SJR Q1Kidney Research and Clinical PracticeOA

In response to the increase in the prevalence of chronic kidney disease (CKD) in Korea, the growth of patients requiring renal replacement therapy and the subsequent increase in medical costs, the rapid expansion of patients with end-stage kidney disease (ESKD), and the decrease in patients receiving home therapy, including peritoneal dialysis, the Korean Society of Nephrology has proclaimed the new policy, Kidney Health Plan 2033 (KHP 2033). KHP 2033 would serve as a milestone to bridge the cur

NephrologyMedicine
6
Article|15 citations·2017
Association of prediabetes-associated single nucleotide polymorphisms with microalbuminuria
Jong Wook Choi, Shinje Moon, Eun Jung Jang, Chang Hwa Lee, Joon-Sung Park
SJR Q1PLoS ONEOA

Increased glycemic exposure, even below the diagnostic criteria for diabetes mellitus, is crucial in the pathogenesis of diabetic microvascular complications represented by microalbuminuria. Nonetheless, there is limited evidence regarding which single nucleotide polymorphisms (SNPs) are associated with prediabetes and whether genetic predisposition to prediabetes is related to microalbuminuria, especially in the general population. Our objective was to answer these questions. We conducted a gen

GeneticsBiochemistry, Genetics and Molecular Biology
7
Article|15 citations·2022
The association between dietary sodium intake and osteoporosis
Susie N. Hong, Jong Wook Choi, Joon-Sung Park, Chang Hwa Lee
SJR Q1Scientific ReportsOA

Abstract The association of inadequate dietary sodium intake with bone mineral density (BMD) and the risk of osteoporosis is controversial. To find the association between low sodium diet and the risk of incipient osteoporosis, we performed a population-based cross-sectional analysis using Tanaka method for estimation 24-h urinary sodium excretion (e24hUNaE Tanaka ) as a candidate indicator of sodium intake. We identified 3869 participants without osteoporosis and classified them into quartiles

Orthopedics and Sports MedicineMedicine
8
Article|12 citations·2025
Association of Appendicular Skeletal Muscle Mass Index and Insulin Resistance With Mortality in Multi‐Nationwide Cohorts
Shinje Moon, Jong Wook Choi, Jung Hwan Park, Dong Sun Kim, You-Hern Ahn, Yeongmin Kim, Sung Hye Kong, Chang‐Myung Oh
SJR Q1Journal of Cachexia Sarcopenia and MuscleOA

BACKGROUND: Although sarcopenia and insulin resistance are closely related, there is limited evidence regarding how they interact to influence mortality across different population groups. The purpose of this study was to examine the relationship between skeletal muscle mass and insulin resistance and its impact on mortality and cardiovascular disease risk using large-scale national data from Korea and the United States. METHODS: We analysed data from the National Health and Nutrition Examinatio

PhysiologyMedicine
9
Article|10 citations·2017
Effect of synergistic interaction between abnormal adiposity-related metabolism and prediabetes on microalbuminuria in the general population
Jong Wook Choi, Il Hwan Oh, Chang Hwa Lee, Joon-Sung Park
SJR Q1PLoS ONEOA

Central obesity and related metabolic components are important risks for microalbuminuria. To describe the effects of interactions between central obesity and related metabolic components on microalbuminuria, we conducted a nation-wide, population-based interaction analysis using cardio-metabolic index (CMI) as a candidate indicator of central obesity and related abnormal lipid metabolism. We recruited native Koreans aged 20 years or older with no medical illness. A total of 5398 participants we

Cardiology and Cardiovascular MedicineMedicine
10
Article|9 citations·2024
Myosteatosis and aortic calcium score on abdominal CT as prognostic markers in non-dialysis chronic kidney disease patients
Ahyun Kim, Chul‐min Lee, Bo-Kyeong Kang, Mimi S. Kim, Jong Wook Choi
SJR Q1Scientific ReportsOA

Abstract We aimed to examine the relationship between abdominal computed tomography (CT)-based body composition data and both renal function decline and all-cause mortality in patients with non-dialysis chronic kidney disease (CKD). This retrospective study comprised non-dialysis CKD patients who underwent consecutive unenhanced abdominal CT between January 2010 and December 2011. CT-based body composition was measured using semiautomated method that included visceral fat, subcutaneous fat, skel

PhysiologyMedicine
11
Article|8 citations·2019
Comparison of laboratory indices of non-alcoholic fatty liver disease for the detection of incipient kidney dysfunction
Jong Wook Choi, Chang Hwa Lee, Joon-Sung Park
SJR Q1PeerJOA

Non-alcoholic fatty liver disease (NAFLD) is closely linked to insulin resistance and related adverse health outcomes. We investigated the non-invasive index of NAFLD that has the best performance in estimating the renal manifestations of metabolic disturbances. This nation-wide, cross-sectional study included 11,836 subjects, using various non-invasive assessments comprising routinely measured clinical and laboratory variables. The subjects were native Koreans aged 20 years or older and had no

EpidemiologyMedicine
12
Article|7 citations·2024
Effect of low muscle mass on total mortality related to metabolic disease in chronic kidney disease patients
Jong Wook Choi, Sung Hye Kong, Yoon Jung Kim, Hye Soo Chung, Jae Myung Yu, Joon-Sung Park, Chang Hwa Lee, Jung Hwan Park, Dong Sun Kim, Chang‐Myung Oh, Shinje Moon
SJR Q1Scientific ReportsOA

Low muscle mass is a risk factor for mortality in patients with chronic kidney disease (CKD). However, it is not clear to what extent low muscle mass contributes to this risk, either independently or in combination with metabolic abnormalities and frailty. This study used data from the National Health and Nutrition Examination Survey 1999–2006 and 2011–2018. Low muscle mass was defined as Appendicular Skeletal Mass Index < 7 kg/m 2 in men or < 5.5 kg/m 2 in women. The follow-up duration was from

PhysiologyMedicine
13
Article|5 citations·2017
Is there a J-shaped relationship between the fatty liver index and risk of microalbuminuria in the general population?
Jong Wook Choi, Il Hwan Oh, Chang Hwa Lee, Joon-Sung Park
SJR Q1Clinica Chimica Acta
EpidemiologyMedicine
14
Article|5 citations·2003
Method of setting Nozzle intervals at the finishing scale breaker
Sung Cho Kim, Jong Wook Choi, Jin Won Choi, Jin Won Choi, Jin Won Choi
KSME International Journal
Mechanics of MaterialsEngineering
15
Article|5 citations·2018
Stabilization of serum alkaline phosphatase in hemodialysis patients by implementation of local chronic kidney disease-mineral bone disorder management strategy: A quality improvement study
Kyubok Jin, Tae Hyun Ban, Ji Yong Jung, Ae Jin Kim, Yaerim Kim, So‐Young Lee, Dong Ho Yang, Bum Soon Choi, Kook‐Hwan Oh, Jieun Kim, Youngjoo Kwon, Jong Wook Choi
SJR Q1Kidney Research and Clinical PracticeOA

BACKGROUND: The aim of this study is to narrow the gap between global guidelines and local practices, we recently established domestic recommendations by adapting the international guidelines for management of chronic kidney disease-mineral bone disorder (CKD-MBD) in patients on maintenance hemodialysis (MHD). This study was undertaken to determine whether application of this guideline adaptation was associated with improved serum mineral profiles in patients with CKD-MBD. METHODS: A total of 35

NephrologyMedicine

Research Areas

PhysiologyEpidemiologyGeneticsNephrologyCardiology and Cardiovascular MedicineComputational Mechanics

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