Jong‐Chul Park
Yonsei University · 医学
研究室紹介
Professor Jong-Chul Park's research lab specializes in biomaterials and tissue engineering, focusing on the development of advanced nanomaterials and surface-modified polymers for regenerative medicine. Key research directions include the design of RGD/PLGA nanofiber matrices and graphene-based substrates for skeletal and neural tissue regeneration, as well as the functionalization of biomaterials like polyurethane and collagen for improved biocompatibility and cell interaction. The lab also investigates the biological effects of natural compounds such as EGCG on cellular senescence and explores novel antimicrobial strategies, including low-amperage electric treatment for seawater disinfection.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15In conclusion, these findings propose that the combination of RGD/PLGA nanofiber matrices and GO can be used as a promising strategy for skeletal tissue engineering and regeneration.
Neural cell adhesion and neurite outgrowth were examined on graphene-based biomimetic substrates. The biocompatibility of carbon nanomaterials such as graphene and carbon nanotubes (CNTs), that is, single-walled and multiwalled CNTs, against pheochromocytoma-derived PC-12 neural cells was also evaluated by quantifying metabolic activity (with WST-8 assay), intracellular oxidative stress (with ROS assay), and membrane integrity (with LDH assay). Graphene films were grown by using chemical vapor d
The influence of mood states on the propensity to use heuristics as expressed in stereotypes was examined using signal detection statistics. Participants experienced happy, neutral, or sad moods and "remembered" whether names connoting race (African American, European American) belonged to social categories (criminal, politician, basketball player). Positive mood increased reliance on heuristics, indexed by higher false identification of members of stereotyped groups. Positive mood lowered sensi
Seawater used in mariculture has been suspected of being a potential source of infection. In this study, the lethal effects of low-amperage electric treatment on microorganisms were examined in natural seawater and in seawater inoculated with Vibrio parahaemolyticus. In both cases, bacteria including V. parahaemolyticus in seawater were completely eliminated in 100 ms by a 0.5-A, 12-V direct current. Electron microscopic investigation of the electrically treated bacteria revealed substantial str
An approach is presented for the graft copolymerization of type I atelocollagen onto the surface of polyurethane (PU) films treated with ozone. Through inducing oxidization to modify PU surface by ozone, peroxide groups are easily generated on the surface. Those peroxides are broken by redox-polymerization, and provide active species which initiate graft polymerization by reacting with amines in the collagen molecules. The ozone oxidation time and voltage could readily control the amount of pero