Jongwon Yoo

BACKGROUND: New or worsening frailty is a common problem in patients with end-stage renal disease (ESRD) during the prolonged time awaiting kidney transplantation. Structured physical activity in the dialysis setting has been shown to mitigate frailty, but little is known about the benefits of home-based exercise. The purpose of this systematic review was to summarize the effects of home-based exercise interventions on indicators of frailty (weakness, slowness, low physical activity, perceived e

Erdheim-Chester disease is a rare inflammatory disease that infiltrates skeletal and extra-skeletal tissue. Chronic kidney disease (CKD) in Erdheim-Chester disease is usually attributed to retroperitoneal lesions that lead to urologic obstruction and hydronephrosis. In this report, we describe a patient diagnosed with Erdheim-Chester disease who eventually developed end-stage kidney disease (ESKD). After complete remission of Erdheim-Chester disease by vemurafenib therapy and 2 years of hemodial

In this preliminary study, total cfDNA levels were elevated in KT patients with COVID-19, subsiding after resolution of infection. High total cfDNA levels may confound dd-cfDNA results, leading to failure to identify rejection. Considering total cfDNA levels is important in interpretation of dd-cfDNA tests for assessment of rejection in KT patients with COVID-19 or other infection.

End-stage renal disease patients who have impaired physical function are denied for transplantation by clinicians concerned about graft/survival outcomes. The purpose of this study was to determine the impact of physical function on graft/survival outcomes at 1-year post-kidney transplantation. Data were analyzed from the Scientific Registry of Transplant Recipients regarding kidney transplantation patients ( N = 218,657) between January 1, 2000 and September 2, 2014. The hazard ratio of 1-year

본 연구는 정부와 공공기관에서 활발하게 구축하고 있는 디지털 문화유산을 메타버스 서비스에서 어떻게 활용할 수 있는지를 살펴봤다. 전문가 인터뷰를 통해 불국사 디지털 문화유산을 메타버스의 4가지 요소인 증강현실, 미러월드, 라이프로깅, 버추얼월드로 어떻게 서비스할 수 있는지를 조사했다. 연구결과, 디지털 문화유산을 메타버스라는 가상공간을 활용할 경우 이용자들에게 양방향의 실감나는 서비스를 제공할 수 있다는 점을 확인했다. 또한 이용자들이 온라인으로 마치 현장에 있는 것과 같은 상황에서 현실에서 이용할 수 없는 부분까지 전시, 체험, 교육할 수 있다는 사실을 알 수 있었다. 이를 통해 디지털 문화유산을 메타버스 서비스로 설계할 경우, 이전과는 다른 차원의 기능과 서비스를 제공할 수 있다는 점을 확인했다. 특히 메타버스의 네 가지 요소별 특징을 고려한 서비스 제공이 가능하다는 결과를 얻었다. 첫째로 증강현실을 활용해 감각을 증강시키는 편의성을 얻을 수 있고, 둘째로 미러월드 요소로 활용해

In recent years, there has been demand for precise estimations of pollutant loads on nationwide scale for the development of appropriate site specific (watershed specific) policies to reduce the negative impact of pollutant loads. River flow data and water quality data that were previously collected by various research institutes and universities for specific research purposes for a limited period was utilized in this study. However, only TMDL 8-day interval flow and water quality data were avai

Background: The long-term success rate of kidney transplantation is disappointing, with repeat transplantation necessary for more than half of recipients. When a repeat kidney transplantation is needed, patients are often elderly and suffer from underlying advanced kidney disease, comorbidities, and adverse effects of immunosuppressants, leading to physical function limitations. Limited physical function is known to hinder access to an initial kidney transplantation, but there is no information

Background: The longevity of transplanted kidney grafts is limited, and more than half of kidney transplant patients need repeat transplants during their lifetimes. However, inequity in access to repeat kidney transplants, especially that resulting from social determinants of health, has not been studied. Methods: Using national data, this retrospective study analyzed kidney transplant recipients with failed kidney grafts (n=63,635) between October 1, 1987, and August 31, 2015, in the United Sta

Cardiovascular and immunological factors increase the levels of uncertainty and risk associated with transplantation. Kidney transplant programs are reluctant to risk performing transplant surgery on high risk candidates because of poor outcomes. Patients with high risk have limited access to kidney transplantation in spite of possible survival benefits of kidney transplantation. We developed four predictive models according to donor types (living donor- and deceased donor-) and transplant outco

BACKGROUND: With the rise of virulent pathogens, the transplant community faces unprecedented challenges in caring for immunocompromised patients. Effective diagnosis, treatment, and follow-up are essential, with prompt immunosuppression adjustment and hospitalization for decompensated patients being critical for survival. OBJECTIVE: Our study aimed to determine if a nurse practitioner-driven care model improves outcomes for kidney transplant recipients who contracted COVID-19. METHODS: We condu

Background: Genetic testing plays an important role in kidney transplantation (KT). Genetic assessment during the pre-KT workup enables more accurate estimation of the risk of recurrent kidney disease and informs treatment of recurrence living-related kidney donor selection. Testing with a broad genetic panel may be beneficial for patients with advanced disease. Here we describe an academic transplant center's early experience with a >380-gene kidney disease panel using NGS, with variant confirm