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Jongwook Oh

Yonsei University · 医学

研究室紹介

Professor Jongwook Oh's research lab focuses on translational and clinical aspects of transplantation immunology, with a particular emphasis on improving outcomes in living donor liver transplantation. The lab investigates immune tolerance strategies, including desensitization protocols for ABO-incompatible transplants, and explores mechanisms of metastatic cancer dissemination, such as the adherent-to-suspension transition in circulating tumor cells. Additionally, the lab examines comorbidities in transplant recipients, such as the risk of herpes zoster and cardiovascular disease in patients with chronic inflammatory conditions like psoriasis. Their work bridges molecular mechanisms with long-term clinical outcomes in diverse patient populations.

transplant immunologyABO-incompatible transplantationcirculating tumor cellsmetastasis mechanismspost-transplant complications

Research Overview

Papers
46
Total Citations
304
Papers (5y)
24
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
24total
2022
2023
2024
2025
2026
Citations per year (5y)
127total
20222023202420252026

Selected Papers

15
1
Article|54 citations·2023
Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination
Hyunbin D. Huh, Yujin Sub, Jongwook Oh, Ye Eun Kim, Ju Young Lee, Hwa-Ryeon Kim, Soyeon Lee, Hannah Lee, Sehyung Pak, Sebastian E. Amos, Danielle Vahala, Jae Hyung Park
SJR Q1Molecular CancerOA

BACKGROUND: Although metastasis is the foremost cause of cancer-related death, a specialized mechanism that reprograms anchorage dependency of solid tumor cells into circulating tumor cells (CTCs) during metastatic dissemination remains a critical area of challenge. METHODS: We analyzed blood cell-specific transcripts and selected key Adherent-to-Suspension Transition (AST) factors that are competent to reprogram anchorage dependency of adherent cells into suspension cells in an inducible and re

Cell BiologyBiochemistry, Genetics and Molecular Biology
2
Article|40 citations·2019
Increased risk of atherosclerotic cardiovascular disease among patients with psoriasis in Korea: A 15‐year nationwide population‐based cohort study
Keum Ji Jung, Tae‐Gyun Kim, Jae Won Lee, Minseok Lee, Minseok Lee, Jongwook Oh, Sang‐Eun Lee, Hyuk‐Jae Chang, Sun Ha Jee, Min‐Geol Lee, Min‐Geol Lee
SJR Q1The Journal of DermatologyOA

The association between psoriasis and risk of atherosclerotic cardiovascular disease has not been thoroughly evaluated in a large longitudinal cohort of an Asian population. We conducted a nationwide population-based retrospective cohort study encompassing more than 1.7 million Koreans with a 15-year follow-up period. The period prevalence of psoriasis was 0.33% among the baseline participants (1997-2000). In Cox proportional hazard analyses, the individuals with psoriasis had a higher adjusted

ImmunologyImmunology and Microbiology
3
Review|38 citations·2019
Immunologic strategies and outcomes in ABO-incompatible living donor liver transplantation
Jongwook Oh, Jong Man Kim
SJR Q1Clinical and Molecular HepatologyOA

Antibody mediated rejection (AMR) after adult ABO-incompatible living donor liver transplantation (ABO-I LDLT) induced hepatic necrosis or diffuse intrahepatic biliary complications, which were related with poor graft and patient survival. Various desensitization protocols have been used to overcome these problems. Since using rituximab, the outcomes of ABO-I LDLT show a similar survival rate to those of ABO-compatible living donor liver transplantation. However, diffuse bile duct complications

SurgeryMedicine
4
Article|30 citations·2023
Pellino-1 promotes intrinsic activation of skin-resident IL-17A–producing T cells in psoriasis
Sung Hee Kim, Jongwook Oh, Won Seok Roh, Jeyun Park, Kyung Bae Chung, Gwang Hee Lee, Youn Sook Lee, Jong Hoon Kim, Heung Kyu Lee, Ho Lee, Chang Ook Park, Do Young ‍Kim
SJR Q1Journal of Allergy and Clinical ImmunologyOA
ImmunologyImmunology and Microbiology
5
Article|17 citations·2019
One‐Year Recipient Morbidity of Liver Transplantation Using Pure Laparoscopic Versus Open Living Donor Right Hepatectomy: Propensity Score Analysis
Jungchan Park, Choon Hyuck David Kwon, Gyu‐Seong Choi, Suk‐Koo Lee, Jong Man Kim, Jongwook Oh, Young Jae Chung, Kyeong Sik Kim, Ji Soo Lee, Kyo Won Lee, Gaab Soo Kim, Mi Sook Gwak
SJR Q1Liver Transplantation

Donor safety and graft results of pure laparoscopic living donor right hepatectomy (LLDRH) have previously been compared with those of open living donor right hepatectomy (OLDRH). However, the clinical outcomes of recipients at 1-year follow-up have never been accurately compared. We aimed to compare 1-year outcomes of recipients of living donor right liver transplantation (LRLT) using pure LLDRH and OLDRH. From May 2013 to May 2017, 197 consecutive recipients underwent LRLT. Donor hepatectomies

SurgeryMedicine
6
Article|16 citations·2019
Incidence and risk factors for herpes zoster after adult liver transplantation
Wontae Kim, Sang Jin Kim, Jongwook Oh, Young Jae Jeong, Jinsoo Rhu, Kyung Sik Kim, Jisoo Lee, Gyu‐Sung Choi, Jong Man Kim, Jae‐Won Joh
SJR Q2Annals of Surgical Treatment and ResearchOA

Patients older than 50 years or with MMF exposure are considered to be at high risk for HZ. Therefore, adult liver recipients with such factors should not be given strong immunosuppression treatments.

EpidemiologyMedicine
7
Article|14 citations·2021
Safety and effectiveness of kidney transplantation using a donation after brain death donor with acute kidney injury: a retrospective cohort study
Kyeong Deok Kim, Kyo Won Lee, Sang Jin Kim, Okjoo Lee, Manuel Lim, Eun Sung Jeong, Jieun Kwon, Jaehun Yang, Jongwook Oh, Jae Berm Park
SJR Q1Scientific ReportsOA

The use of kidneys from donation after brain death (DBD) donors with acute kidney injury (AKI) is a strategy to expand the donor pool. The aim of this study was to evaluate how kidney transplantation (KT) from a donor with AKI affects long-term graft survival in various situations. All patients who underwent KT from DBD donors between June 2003 and April 2016 were retrospectively reviewed. The KDIGO (Kidney Disease: Improving Global Outcomes) criteria were used to classify donor AKI. The cohort

TransplantationMedicine
8
Article|14 citations·2019
Clinical and Radiographic Characteristics of Neuro-Behçet's Disease in South Korea
Seung Woo Kim, Tae‐Gyun Kim, Jongwook Oh, Do Young ‍Kim, Young‐Chul Choi, Seung Min Kim, Ha Young Shin, Dongsik Bang
SJR Q2Journal of Clinical NeurologyOA

Approximately 1% of the patients with suspected BD exhibited NBD. Neurologists must understand the clinical characteristics of NBD in order to perform the differential diagnosis and management of these patients.

OphthalmologyMedicine
9
Article|12 citations·2021
Risk of psychiatric diseases among patients with psoriasis in Korea: A 12‐year nationwide population‐based cohort study
Jongwook Oh, Keum Ji Jung, Tae‐Gyun Kim, Hae Won Kim, Sun Ha Jee, Min‐Geol Lee
SJR Q1The Journal of DermatologyOA

The association between psoriasis and risk of psychiatric diseases has not been thoroughly evaluated in a large longitudinal cohort of the Asian population. We conducted a nationwide cohort study encompassing more than 1.6 million Koreans with a 12-year follow-up period. Patients were considered to be in the psoriasis cohort if they had an incident diagnostic code for psoriasis and included patients were followed up until they developed any psychiatric disease. In adjusted models, psoriasis pati

ImmunologyImmunology and Microbiology
10
Article|10 citations·2022
Safety, Efficacy, and Drug Survival of Colchicine in Recurrent Aphthous Stomatitis in a Real-World Setting
Jongwook Oh, Jae Won Lee, Kyung Bae Chung, Dongsik Bang, Do Young ‍Kim
SJR Q3Annals of DermatologyOA

In patients with RAS, colchicine may be an effective and safe treatment amenable to long-term maintenance. Monitoring of adverse events within 2 weeks after initiating treatment is advisable to ensure safe administration.

PeriodonticsDentistry
11
Review|7 citations·2020
Classification of facial and truncal segmental vitiligo and its clinical courses including recurrence rate and patterns: a retrospective review of 956 patients
Jongwook Oh, R.W. Lee, Hee Ra Lee, Seon Bok Lee, Hyun Jeong Ju, J. Park, H.R. Park, J.H. Park, S‐K Hann, Abdurrahman Almurayshid, Jeonghyun Shin, Hee Young Kang
SJR Q1British Journal of DermatologyOA

title: Classification of facial and truncal segmental vitiligo and its clinical courses including recurrence rate and patterns: a retrospective review of 956 patients, doi: 10.1111/bjd.19661, category: Article

Cell BiologyBiochemistry, Genetics and Molecular Biology
12
Article|4 citations·2019
Use of Topical Rapamycin as Maintenance Treatment after a Single Session of Fractionated CO2 Laser Ablation: A Method to Enhance Percutaneous Drug Delivery
Jongwook Oh, Jihee Kim, Won Jai Lee, Ju Hee Lee
SJR Q3Annals of DermatologyOA

device.

PhysiologyMedicine
13
Article|4 citations·2023
Increased Risk of Renal Malignancy in Patients with Moderate to Severe Atopic Dermatitis
Jongwook Oh, Hyun Ju Oh, Kyungdo Han, Heon Yung Gee, Ji Hyun Lee
SJR Q1CancersOA

BACKGROUND: Evidence for an association between atopic dermatitis (AD) and cancer is still insufficient. In particular, the association between the risk of renal malignancy and the severity of AD has not been thoroughly investigated. OBJECTIVE: To investigate the risk of renal malignancy and determine the association between AD severity and cancer risk using data from the Korean National Health Insurance Service (KNHIS) database. METHODS: We performed a population-based cohort study using the Na

DermatologyMedicine
14
Article|2 citations·2024
High level of gamma-glutamyltransferase is a possible risk factor for psoriasis: A nationwide population-based cohort study
Jongwook Oh, Kyungdo Han, Jee Yun Doh, Heon Yung Gee, Ji Hyun Lee
SJR Q2Indian Journal of Dermatology Venereology and LeprologyOA

Background Gamma-glutamyl transferase (GGT) has been associated with coronary heart disease, diabetes mellitus, and hypertension, but its association with psoriasis has not yet been elucidated. Aims We conducted this study to determine the association between the risk of psoriasis and the serum GGT. Methods We conducted a nationwide population-based study. A total of 9,939,350 people met the enrolment criteria. The study population was classified into four groups based on GGT levels and the risk

ImmunologyImmunology and Microbiology
15
Article|1 citations·2007
Bilateral breast cancer
Jongwook Oh, B. Park
SJR Q1Journal of Clinical Oncology

17073 Background: The clinical significance of bilateral breast cancer is unclear and its influence on prognosis is controversial. The aim of this study is to assess the impact of bilateral breast cancer on the prognosis compared with unilateral breast cancer and examine clinicopathologic characteristics of Bilateral and Unilateral breast cancer. Methods: 108 patients included in this study from Jan 1980 to Dec 2005 and all information regarding medical and family history of breast cancer came f

OncologyMedicine

Research Areas

ImmunologySurgeryDermatologyCell BiologyOncologyMolecular Biology

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