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Jun Hee Lee

Ewha Womans University · 医学

研究室紹介

Professor Jun Hee Lee's research lab focuses on biomedical materials and neurorehabilitation, with a strong emphasis on developing bioinspired adhesives for tissue engineering and advancing therapeutic strategies for neurological disorders. The lab investigates mussel-inspired adhesive polymers—particularly chitosan-catechol systems—for use in 3D bioprinting and regenerative medicine, while also exploring the pathophysiology of neurodegenerative conditions such as dementia and post-stroke complications. A key area of interest is the impact of genetic factors, such as APOE genotype, on stroke risk and cognitive outcomes, with translational research on exercise and shockwave therapy to improve functional recovery. The lab also examines food safety issues related to biogenic amines in traditional fermented foods, linking microbiology and clinical health outcomes.

biomaterialsneurorehabilitation3D bioprintingbiogenic aminesstroke recovery

Research Overview

Papers
51
Total Citations
838
Papers (5y)
16
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
16total
2022
2023
2024
2025
2026
Citations per year (5y)
42total
20222023202420252026

Selected Papers

15
1
Review|130 citations·2019
Bacterial Production and Control of Biogenic Amines in Asian Fermented Soybean Foods
Jae‐Hyung Mah, Young Min Park, Young Hun Jin, Junhee Lee, Han‐Joon Hwang
SJR Q1FoodsOA

Fermented soybean foods possess significant health-promoting effects and are consumed worldwide, especially within Asia, but less attention has been paid to the safety of the foods. Since fermented soybean foods contain abundant amino acids and biogenic amine-producing microorganisms, it is necessary to understand the presence of biogenic amines in the foods. The amounts of biogenic amines in most products have been reported to be within safe levels. Conversely, certain products contain vasoacti

Molecular BiologyBiochemistry, Genetics and Molecular Biology
2
Article|94 citations·2017
Development of Printable Natural Cartilage Matrix Bioink for 3D Printing of Irregular Tissue Shape
Chi Sung Jung, Byeong Kook Kim, Junhee Lee, Byoung‐Hyun Min, Sang‐Hyug Park
SJR Q1Tissue Engineering and Regenerative Medicine
Biomedical EngineeringEngineering
3
Article|73 citations·2018
Chitosan-catechol: a writable bioink under serum culture media
Daiheon Lee, Joseph P. Park, Mi‐Young Koh, Pureum Kim, Junhee Lee, Mikyung Shin, Haeshin Lee
SJR Q1Biomaterials Science

Mussel-inspired adhesive coatings on biomedical devices have attracted significant interest due to their unique properties such as substrate independency and high efficiency. The key molecules for mussel-inspired adhesive coatings are catechol and amine groups. Along with the understanding of catechol chemistry, chitosan-catechol has also been developed as a representative mussel-inpired adhesive polymer that contains catechol and amine groups for adhesiveness. Herein, we demonstrated the direct

Biomedical EngineeringEngineering
4
Article|42 citations·2001
Complications Associated With Silicone Intracanalicular Plugs
Junhee Lee, Joseph C. Flanagan
SJR Q2Ophthalmic Plastic and Reconstructive Surgery

Silicone intracanalicular plugs may be difficult to remove and may be associated with significant lacrimal complications.

MicrobiologyMedicine
5
Article|31 citations·2019
Formation of Biogenic Amines in Pa (Green Onion) Kimchi and Gat (Mustard Leaf) Kimchi
Junhee Lee, Young Hun Jin, Young Kyoung Park, Se Jin Yun, Jae‐Hyung Mah
SJR Q1FoodsOA

In this study, biogenic amine content in Pa (green onion) kimchi and Gat (mustard leaf) kimchi, Korean specialty kimchi types, was determined by high-performance liquid chromatography (HPLC). Many kimchi samples contained low levels of biogenic amines, but some samples had histamine and tyramine content over the safe levels. Based on the comparative analysis between the ingredient information on food labels and biogenic amine content of kimchi samples, Myeolchi-aekjeot appeared to be an importan

Molecular BiologyBiochemistry, Genetics and Molecular Biology
6
Article|15 citations·2018
Effects of exercise training on stroke risk factors, homocysteine concentration, and cognitive function according the APOE genotype in stroke patients
Junhee Lee, Sangmin hong, Yun‐A Shin
SJR Q2Journal of Exercise RehabilitationOA

The apolipoprotein E (<i>APOE</i>) gene has been suggested to be associated with stroke and dementia. However, the effects of exercise training on dementia according to the <i>APOE</i> genotype are not consistent to those reported by previous studies. Therefore, we examined the effects of exercise training on stroke risk factors including blood pressure, lipid profiles, homocysteine (Hcy) concentrations, and cognitive function according to the <i>APOE</i> genotype in stroke patients. We examined

RheumatologyMedicine
7
Article|13 citations·2024
Effectiveness of Extracorporeal Shock Wave Therapy after Botulinum Toxin Injection for Post-Stroke Upper Extremity Spasticity: A Randomized Controlled Study
Junhee Lee, Seung Nam Yang
SJR Q1ToxinsOA

Post-stroke spasticity is a common complication that limits the functional performance of patients. Botulinum toxin (BTx) is an effective treatment for spasticity. Numerous researchers have applied extracorporeal shock wave therapy (ESWT) to address post-stroke spasticity, yielding positive clinical outcomes. We aimed to clarify the add-on effects of ESWT on BTx therapy for spasticity in patients with post-stroke. Sixteen eligible patients with upper extremity spasticity after stroke were recrui

NeurologyMedicine
8
Article|13 citations·2022
NPEX
Junhee Lee, Seongjoon Hong, Hakjoo Oh
Proceedings of the 44th International Conference on Software Engineering

We present NPEX, a new technique for repairing Java null pointer exceptions (NPEs) without tests. State-of-the-art NPE repair techniques rely on test suites written by developers for patch validation. Unfortunately, however, those are typically future test cases that are unavailable at the time bugs are reported or insufficient to identify correct patches. Unlike existing techniques, NPEX does not require test cases; instead, NPEX automatically infers the repair specification of the buggy progra

SoftwareComputer Science
9
Article|11 citations·2014
이슈소유권, 위기책임성인식, 그리고 대응전략 제시순서에 따른 정서와 위기커뮤니케이션 효과
이준희, 차희원

본 연구는 이슈소유권과 위기책임성인식, 메시지 제시 순서가 공중의 정서와 위기커뮤니케이션 효과에 미치는 영향을 알아보고자 하였다. 연구 결과, 위기책임성인식의 중요성과 메시지 제시순서에 따른 정서 차이를 확인할 수 있었다. 특히 위기책임성인식이 낮을 경우, 방어전략이 먼저 제시되는 유형에서 위기커뮤니케이션효과가 더 높았고, 희생양 만들기보다 상기시키기 전략이 사용될 경우 동정의 수준과 위기커뮤니케이션 효과가 더 높게 나타났다. 이슈소유권은 위기책임성인식 및 대응전략 유형과 상호작용하며 정서와 위기커뮤니케이션효과에 영향을 미치는 것으로 나타났다. 또한, 동정이 분노보다 큰 영향력을 미치는 것으로 나타나, 위기 시 긍정 정서의 연구 필요성을 확인하였다. 본 연구는 위기책임성인식과 메시지 제시순서에 따른 대응전략 유형이 정서와 위기커뮤니케이션효과에 미치는 영향력을 실증적으로 확인하였고, 특히 그동안 위기와 정서 관련 연구에서 활발히 다루어지지 않았던 동정에 대한 적극적 연구의 필요성을 발

10
Article|10 citations·2023
Efficiency of botulinum toxin injection into the arm on postural balance and gait after stroke
Junhee Lee, Ji Eun Park, Byung Heon Kang, Seung Nam Yang
SJR Q1Scientific ReportsOA

The purpose of this study was to clarify the association between improvement of spasticity in hemiplegic patient's upper extremity with Botulinum toxin injection and improvement in postural balance and gait function. For this prospective cohort study, sixteen hemiplegic stroke patients with upper extremity spasticity were recruited. The plantar pressure with gait parameters, postural balance parameters, Modified Ashworth Scale, and Modified Tardieu Scale were evaluated before, 3 weeks and 3 mont

NeurologyMedicine
11
Article|9 citations·2020
Determining the Most Appropriate Assistive Walking Device Using the Inertial Measurement Unit-Based Gait Analysis System in Disabled Patients
Junhee Lee, Chang Hoon Bae, Aeri Jang, Seoyon Yang, Hasuk Bae
SJR Q1Annals of Rehabilitation MedicineOA

OBJECTIVE: To evaluate the gait pattern of patients with gait disturbances without consideration of defilades due to assistive devices. This study focuses on gait analysis using the inertial measurement unit (IMU) system, which can also be used to determine the most appropriate assistive device for patients with gait disturbances. METHODS: Records of 18 disabled patients who visited the Department of Rehabilitation from May 2018 to June 2018 were selected. Patients' gait patterns were analyzed u

Physical Therapy, Sports Therapy and RehabilitationHealth Professions
12
Article|6 citations·2016
이슈 유형, 정서적 관여 수준, 규범유형이 분노 수준과 위기커뮤니케이션효과에 미치는 영향
이준희, 차희원

본 연구는 기존 연구들을 보완하여 이슈 유형, 정서적 관여 수준, 규범 유형과 분노수준에따른 위기커뮤니케이션 효과에 대해 확인하고, 각 변인들 간의 영향 관계와 상호작용 등을 살펴보려 하였다. 연구 결과, 공중들은 경제적 이슈에 위기가 발생한 경우와 정서적 관여 수준이 높은 이슈에 위기가 발생한 경우 더 강한 분노를 느꼈다. 규범 유형의 경우 본 연구에서는구체적 보상 메시지가 없는 사회규범 유형이 제시될 경우 더 강한 분노를 보였다. 또한 경제적이슈에 위기가 발생할 경우 시장규칙 메시지가 제시되면 분노수준이 감소하고 메시지효과가 높아졌으며, 정서적 관여 수준이 낮은 이슈에 위기 발생 시에도 시장규칙이 제시될 경우 분노수준이 감소하고 행동의지가 낮아졌다. 분노수준은 정서적 관여 수준과 행동의지 사이를 매개하고, 규범 유형과 메시지효과 사이를 매개하는 것으로 나타났다. 본 연구는 정서적 관여의 개념을 이슈와 접목시켰다는 점과 개별적으로 논의되어 오던 이슈 유형과 이슈에 대한 정서적 관여

13
Article|2 citations·2022
PR 커뮤니케이션 관점의 디지털 시민참여에 대한 영향요인 연구: 이슈 가치 유형을 중심으로
이준희, 유승희, 김수진

연구목적 본 연구의 목적은 PR 커뮤니케이션에서 디지털 시민참여가 갖는 의미를 검토하고 디지털 시민참여에 영향을 미치는 요인들을 알아보는 데 있다. 이를 위해 이슈 유형을 구분하고 이슈 유형에 따라 디지털 시민참여 영향요인 이 어떤 차이를 보이는지 검토하고자 한다. 연구방법 본 연구에서는 디지털 시민참여에 대한 이슈 유형의 차이를 검토하기 위해 이슈 유형을 개인 가치 강조 이슈(탄소 세)와 사회 가치 강조 이슈(아동 복지)로 구분하여 온라인 준 실험을 시행했다. 실험은 국내 거주하는 성인 491명 을 대상으로 온라인 조사회사를 통해 시행했다. 연구결과 개인 가치 강조 이슈에 대한 공중들의 디지털 시민참여에는 태도와 참여효능감이 주요하게 영향을 미쳤으며 특히 사회 가치 강조 이슈는 개인 가치 강조 이슈보다 분노와 불안 같은 감정적 요소의 영향이 크게 나타났다. 결론 및 함의 본 연구에서는 이슈 유형을 공중이 판단하는 이슈 가치에 따라 유형화하고, 디지털 시민참여에 대한 이슈 유형의 차

14
Article|1 citations·2023
Mapping the Species Richness of Woody Plants in Republic of Korea
Junhee Lee, Youngjae Yoo, Raeik Jang, Seong-Woo Jeon
SJR Q1SustainabilityOA

As climate change continues to impact the planet, the importance of forests is becoming increasingly emphasized. The International Co-operative Program on the Assessment and Monitoring of Air Pollution Effects on Forests (ICP Forests) has been monitoring and assessing forests in 40 countries since 1985. In Republic of Korea, the first Forest Health Management (FHM) survey was a nationwide sample point assessment conducted between 2011 and 2015. However, there are limitations in representing the

Ecological ModelingEnvironmental Science
15
Book Chapter|1 citations·2023
Quantitative Pressure Measurement in Areas at High Risk of Pressure Ulcers in Different Positions: Pilot Study
Junhee Lee, Joon Shik Yoon
SJR Q2Lecture notes in computer scienceOA

Abstract This study aimed to quantitatively analyze pressure parameters in different high-risk areas depending on the position. We reviewed the clinical records of trials of 20 healthy adults on a multi-actuated bed accompanied with pressure sensor mat. We collected average, maximal, minimal pressure, and area in the supine and bilateral side-tilt positions. Also, we analyzed the difference between each at-risk area, depending on positions. In the supine position, pressure parameters of the head

Occupational TherapyHealth Professions

Research Areas

Molecular BiologySurgeryBiomedical EngineeringSoftwareNeurologyAtomic and Molecular Physics, and Optics

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