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Jun-Kyu Huang

Yonsei University · 医学

研究室紹介

Professor Jun-Kyu Huang's research lab specializes in neurological and neurosurgical disorders, with a focus on epilepsy surgery, pediatric neurosurgery, and rare neurological conditions such as mucormycosis and neurofibromatosis. The lab investigates innovative surgical techniques—like disconnection surgery and C1L-assisted posterior fossa expansion—to improve outcomes in patients with drug-resistant epilepsy and cranial volume disorders. It also explores advanced diagnostic and therapeutic strategies, including deep learning for gait analysis and multidisciplinary management of metastatic and malignant tumors in immunocompromised patients.

epilepsy surgeryneurofibromatosismucormycosisneurosurgical innovationgait analysis

Research Overview

Papers
17
Total Citations
37
Papers (5y)
9
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
9total
2022
2023
2024
2025
2026
Citations per year (5y)
10total
20222023202420252026

Selected Papers

15
1
Article|12 citations·2019
From Resection to Disconnection for Seizure Control in Pediatric Epilepsy Children
Jun Kyu Hwang, Dong-Seok Kim
SJR Q2Journal of Korean Neurosurgical SocietyOA

Epilepsy surgery revealed dramatically improved seizure outcomes over medical therapy in drug-resistant epilepsy patients. Children with epilepsy, however, have multiple epileptic focuses which require multilobar resection for better seizure outcome. Multilobar resection has not only the several severe surgical complications, such as hydrocephalus and shunt-related craniosynostosis, due to intracranial volume reduction. Isolation method (disconnection surgery) was progressively studied over epil

Psychiatry and Mental healthMedicine
2
Article|7 citations·2021
The feasibility of performing multiple burr hole surgery in pediatric moyamoya patients as a response to failed mEDAS
Jun Kyu Hwang, Eun-Kyung Park, Jinna Kim, Hoon‐Chul Kang, Dong-Seok Kim, Kyu‐Won Shim
SJR Q2Child s Nervous SystemOA
RheumatologyMedicine
3
Article|5 citations·2023
Effectiveness of C1 Laminectomy for Chiari Malformation Type 1: Posterior Fossa Volume Expansion and Syrinx-Volume Decrease Rate
Jun Kyu Hwang, Eun-Kyung Park, Kyu‐Won Shim, Dong-Seok Kim
SJR Q2Yonsei Medical JournalOA

C1L was effective in increasing posterior fossa volume expansion, both with and without duraplasty. A more rapid decrease in syrinx volume occurred when C1L was combined with duraplasty.

Public Health, Environmental and Occupational HealthMedicine
4
Article|4 citations·2017
Late-Developing Metastatic Malignant Melanoma in the Thoracic Spine Originating from Choroidal Melanoma
Jun Kyu Hwang, Kyung Hyun Kim, Ji Sup Kim, Sung Jun Ahn, Sung Uk Kuh
Korean Journal of SpineOA

A 54-year-old woman visited Gangnam Severance Hospital for left side flank pain. She had a history of total removal of malignant melanoma on the left eye ball 20 years prior. No evaluation had been performed since then. A paravertebral mass at thoracic ninth level (T9) was discovered on spinal magnetic resonance imaging, and pathology confirmed malignant melanoma. Following positron emission tomography-computed tomography, no other metastasis was discovered. After removal of the paravertebral ma

Molecular BiologyBiochemistry, Genetics and Molecular Biology
5
Article|2 citations·2025
Treatment of Plexiform Neurofibromas : Current Perspectives on Surgery and Medical Treatment
Jun Kyu Hwang, Se Hoon Kim, Dong-Seok Kim
SJR Q2Journal of Korean Neurosurgical SocietyOA

Plexiform neurofibromas (PNFs), a critical clinical feature of neurofibromatosis type 1, mainly involve several peripheral nerve branches and extend widely, including the skin and bones and the internal organs. Determining the appropriate treatment is difficult. Additionally, they possess the potential to develop into malignant peripheral nerve sheath tumors (MPNSTs), which are linked to an extremely poor prognosis. Active treatment is critical in patients with symptoms or progressive tumor grow

NeurologyMedicine
6
Article|2 citations·2025
Distinguishing Pathologic Gait in Older Adults Using Instrumented Insoles and Deep Neural Networks
W.H. Lee, Jin Hyun, Seungwon Choi, Sangbu Yun, Kwangho Chung, Seok Jong Chung, Jun Kyu Hwang, Eun Joo Yang, Youngjoo Lee, Na Young Kim
SJR Q1IEEE Journal of Biomedical and Health Informatics

Gait abnormalities are common in the older population owing to aging- and disease-related changes in physical and neurological functions. Differentiating the causes of gait abnormalities is challenging because various abnormal gaits share a similar pattern in older patients. Herein, we propose a deep neural network (DNN) model to classify disease-specific gait patterns in older adults using commercialized instrumented insoles. This study included 150 patients aged ≥ 65 years, divided into the fo

Biomedical EngineeringEngineering
7
Article|1 citations·2002
A Study of Clinical Investigations of Pulmonary Tuberculoma
Suk Ho Song, Hye Sook Hahn, Sun Young Kyung, Jun Kyu Hwang, Chang Hyeok An, Young Hee Lim, Gye Young Park, Jeong Woong Park, Seong Hwan Jeong
SJR Q2Tuberculosis and Respiratory DiseasesOA

Background A pulmonary tuberculoma is one of the most common causes of a solitary pulmonary lesion. Treating a tuberculoma is still controversial and there are few reports on antituberculosis chemotherapy. In this study, the clinical findings and changes in the size of tuberculomas on a radiograph after completing antiuberculosis chemotherapy was investigated. Methods The medical records, an chest radiographs of 18 pulmonary tuberculoma patients who were admitted to the Gachon medical school, Gh

SurgeryMedicine
8
Article|1 citations·2002
A Case Intestinal Mucormycosis Healing of Ulcer after Only Amphotericin B Treatment.
Hye Sook Hahn, Hyuk Sang Jung, Suk Ho Song, Do Yoon Lim, Sun Young Kyung, Jun Kyu Hwang, Moon Gi Chung, Yang Suh Koo, Yu Kyung Kim, Ju Hyun Kim, Dong Kyoon Park, Hyun Yee Cho
SJR Q2Clinical Endoscopy

Mucormycosis is an uncommon, frequently fatal, opportunistic fungal infection and usually occur in immunocompromised patients. Rhinocerebral and pulmonary disease are the common forms but intestinal infection is an extremely rare form of the disease. Invasive intestinal mucormycosis is usually fatal, therefore, few cases reported survival after early diagnosis and surgical resection combined with antifungal treatment. Because of high mortality after surgery, the healing of ulcers caused by intes

Infectious DiseasesMedicine
9
Article|1 citations·2002
Two Cases of Microscopic Polyangiitis with Honeycomb Lung
Hye Sook Hahn, Jun Kyu Hwang, Hyuk Sang Jung, Suk Ho Song, Kwon Wook Joo, Gye Young Park, Jong Ho Lee, Young‐Ha Oh, Hyoun Joo Lee
SJR Q2Tuberculosis and Respiratory DiseasesOA

Microscopic polyangiitis is a systemic small-vessel vasculitis that is associated primarily with necrotizing glomerulonephritis and pulmonary capillaritis. A recurrent and diffuse alveolar hemorrhage due to pulmonary capi llaritis is the main clinical manifestation of lung involvement. Recently, an interstitial lung disease that mimics idiopathic pulmonary fibrosis was reported to be rarely associated with microscopic polyangiitis. Here we report two patients with microscopic polyangiitis who sh

Pulmonary and Respiratory MedicineMedicine
10
Article|1 citations·2002
The Relationship of Serum Angiotensin Converting Enzyme (ACE), Angiotensin II and Clinical Markers in the Idiopathic Interstitial Pneumonia
Sun Young Kyung, Hye Sook Hahn, Suk Ho Song, Jun Kyu Hwang, Young‐Hee Lim, Chang Hyeok An, Gye Young Park, Jung Woong Park, Seong Hwan Jeong, Seung Yeon Ha, Jae Woong Lee
SJR Q2Tuberculosis and Respiratory DiseasesOA

Background There have been several studies showing that angiotensin II and the angiotensin convertingenzyme (ACE) contribute to the activation of fibroblast including the pulmonary fibrosis, and apoptosis of the al veolar epithelium in idiopathic intersititial pneumonia. This study was performed to identify the relationship between the serum angiotensin II. ACE and the pulmonary function test (PFT), the dyspnea score, and the cell fraction of the bronchoalveolar lavage fluid (BALF). Methods Twen

Pulmonary and Respiratory MedicineMedicine
11
Article|1 citations·2025
Serial Assessment of Gait Changes After Interventions Using Smart Insole in a Patient With iNPH: A Proof-of-Concept Case Report
W.H. Lee, Seung-Ick Choi, Seok Jong Chung, Jun Kyu Hwang, Na Young Kim
Brain & NeurorehabilitationOA

Improvement in gait after a cerebrospinal fluid (CSF) tap test is a key indicator for shunt surgery in idiopathic normal pressure hydrocephalus (iNPH) patients. However, quantitative analysis of gait requires sophisticated equipment and specialists that limit practical use. Development of Bluetooth-connected sensors offers affordable way to assess gait. We present a case of iNPH patient in whom gait changes were serially assessed using a smart insole before and after intervention, which helped i

Cellular and Molecular NeuroscienceNeuroscience
12
Article|0 citations·2026
Generative AI–Assisted Medical Illustrations in Pediatric Neurosurgery: Workflows, Ethical Safeguards, and Journal Policy Considerations
Jun Kyu Hwang, Dong-Su Jang
SJR Q2Journal of Korean Neurosurgical SocietyOA

Generative artificial intelligence (AI) has emerged as a transformative tool for creating high-quality visual materials in medical research and education. In pediatric neurosurgery, where ethical and legal constraints limit the use of real patient photographs, AI-assisted illustrations offer significant potential. However, concerns regarding clinical accuracy, intellectual property, and the protection of vulnerable pediatric patients necessitate rigorous oversight. We present a human-in-the-loop

Health InformaticsMedicine
13
Article|0 citations·2024
Endoscopic Surgery for Deeply Located Intracranial Cysts: Risk Factors for Re-Operation and Symptom Improvement
Jun Kyu Hwang, Ju-Seong Kim, Eun-Kyung Park, Kyu‐Won Shim, Dong-Seok Kim
SJR Q2Yonsei Medical JournalOA

Purpose:We investigated the results of endoscopic fenestration for deeply located intracranial cysts (DLICs), risk factors for reoperation, and symptom improvement. Materials and Methods:We included 51 patients with DLICs who underwent endoscopic fenestration between November 2006 and October 2022.The median age was 520 years (6 days-67 years), and 36 (70.6%) patients were aged <20 years.The male-tofemale ratio was 1.3:1.The ventriculoscope was used to fenestrate the cysts, which had diameters u

Cellular and Molecular NeuroscienceNeuroscience
14
Article|0 citations·2025
Effectiveness of Intracerebral Hemorrhage Aspiration with Catheter Insertion: Impact on Hematoma Volume and Symptom Improvement
Jun Kyu Hwang, Na Young Kim, Won Joo Jeong, Chang Ki Jang, Jae Whan Lee, Tae Im Yi, Kwang‐Chun Cho
SJR Q2Brain SciencesOA

Background: Catheter insertion is the most commonly used method for treating intracerebral hemorrhage (ICH). Simultaneous hematoma aspiration allows for faster decompression than catheter insertion alone. Methods: Between March 2020 and Apri1 2024, 49 patients (25 men and 24 women) with ICH underwent ICH catheter insertion. Thirty-two patients (Group A) underwent intraoperative aspiration simultaneously with ICH catheter insertion. The other seventeen patients underwent catheter insertion alone

NeurologyMedicine
15
Article|0 citations·2001
Effect of Inhaled Fluticasone Propionate on Hypothalamic-Pituitary-Adrenal Axis in Bronchial Asthma Patient
Jun Kyu Hwang, Ho Meong Lee, Yang Won No, Gye Young Park, Chong Wung Park, Jae Kyung Park, Seong Hwan Jeong, Gui Hyun Nam, Hong Kyu Kim, Hye Young Park, Moon Ho Kang
SJR Q2Tuberculosis and Respiratory DiseasesOA

Background Inhaled glucocorticoids are the medical treatment of choice in asthma patients. Fluticasone propionate is one of the most effective inhaled corticosteroids and has been reported to have minimal effect on the hypothalamic-pituitary-adrenal axis at the recommended dose. However, reports of long-term trials characterizing their systemic safety with chronic use are rare. This study was designed to evaluate the long-term safety of inhaled fluticasone propionate to the hypothalamic-pituitar

PhysiologyMedicine

Research Areas

Cellular and Molecular NeuroscienceRheumatologyNeurologyPulmonary and Respiratory MedicinePsychiatry and Mental healthPublic Health, Environmental and Occupational Health

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