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Jungirl Seok

Seoul National University · 医学

研究室紹介

Professor Jungirl Seok's research lab specializes in head and neck oncology, with a focus on improving diagnostic accuracy, surgical planning, and prognostic prediction in salivary gland and thyroid cancers. The lab integrates advanced medical imaging, deep learning, and 3D printing technologies to develop personalized models for tumor visualization and surgical guidance. Key research directions include identifying clinical and radiological predictors of metastasis in adenoid cystic carcinoma and papillary thyroid carcinoma, as well as developing AI-driven tools for anatomical structure detection in otolaryngological endoscopy.

head and neck cancerdeep learning3D printingthyroid cancermedical imaging

Research Overview

Papers
65
Total Citations
718
Papers (5y)
30
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
30total
2022
2023
2024
2025
2026
Citations per year (5y)
150total
20222023202420252026

Selected Papers

15
1
Article|42 citations·2019
Lung metastasis in adenoid cystic carcinoma of the head and neck
Jungirl Seok, Doh Young Lee, Won Shik Kim, Woo‐Jin Jeong, Eun‐Jae Chung, Young Ho Jung, Seong Keun Kwon, Tack‐Kyun Kwon, Myung‐Whun Sung, Soon‐Hyun Ahn
SJR Q1Head & Neck

BACKGROUND: Distant metastasis of adenoid cystic carcinoma (ACC) is most commonly identified in the lung, but risk factors are still on debate. METHODS: Risk factors for lung metastasis were evaluated by using Cox proportional hazards model and Kaplan-Meier curves. RESULTS: Of 112 patients, 48% had distant metastasis; 94.4% of whom had lung metastasis. Univariable analysis revealed sublingual or minor salivary gland, tumor size ≥2.5 cm, and perineural invasion as risk factors (hazard ratio [HR]:

SurgeryMedicine
2
Article|42 citations·2019
The Difference in the Clinical Features Between Carcinoma ex Pleomorphic Adenoma and Pleomorphic Adenoma
Jungirl Seok, Se Jin Hyun, Woo‐Jin Jeong, Soon‐Hyun Ahn, Hyojin Kim, Young Ho Jung
SJR Q3Ear Nose & Throat JournalOA

Carcinoma ex pleomorphic adenoma (CXPA) arises from the primary or recurrent benign pleomorphic adenoma. The purpose of this study was to evaluate the clinical features that could be referenced in the differentiation. The medical records of 221 patients with pleomorphic adenoma and 15 patients with CXPA were retrospectively reviewed. Clinical characteristics, computed tomography and magnetic resonance imaging findings, and surgical pathology were analyzed. Patients with CXPA were older (55.1 vs

SurgeryMedicine
3
Article|24 citations·2017
Correlation between olfactory severity ratings based on olfactory function test scores and self-reported severity rating of olfactory loss
Jungirl Seok, Ye Ji Shim, Chae‐Seo Rhee, Jeong‐Whun Kim
SJR Q2Acta Oto-Laryngologica

There were significant correlations between BTT scores and self-rated severity scales (r = 0.619, p < 0.001) and between CCSIT scores and self-rated severity scales (r = 0.597, p < 0.001) after adjustment for age, sex, and medical conditions. Using discriminant analysis for both BTT and CCSIT, scores 0-4 could be statistically rated as anosmia, scores 5 and 6 as severe hyposmia, scores 7 and 8 as moderate hyposmia, and scores 9-12 as normosmia (Wilks's lambda = 0.605, p < 0.001 for BTT and Wilks

Sensory SystemsNeuroscience
4
Article|23 citations·2021
Factors Affecting Central Node Metastasis and Metastatic Lymph Node Ratio in Papillary Thyroid Cancer
Jungirl Seok, Chang Hwan Ryu, Seog Yun Park, Chang Yoon Lee, Young Ki Lee, Yul Hwangbo, Eun Kyung Lee, You Jin Lee, Tae Sung Kim, S. Kim, Yuh‐Seog Jung, Junsun Ryu
SJR Q1Otolaryngology

Objective Despite the growing evidence that metastatic lymph node ratio (MLNR) is a valuable predictor for the prognosis of papillary thyroid carcinoma, it has not yet been fully determined which factors give the ratio predictive value independent of the number of metastatic lymph nodes (MLNs). Study Design Retrospective cohort study. Setting A comprehensive cancer center. Methods Recurrence and clinicopathologic factors were analyzed in 2409 patients with papillary thyroid carcinoma who underwe

Endocrinology, Diabetes and MetabolismMedicine
5
Article|17 citations·2021
A Personalized 3D-Printed Model for Obtaining Informed Consent Process for Thyroid Surgery: A Randomized Clinical Study Using a Deep Learning Approach with Mesh-Type 3D Modeling
Jungirl Seok, Sungmin Yoon, Chang Hwan Ryu, Seok-Ki Kim, Junsun Ryu, Yuh‐Seog Jung
SJR Q2Journal of Personalized MedicineOA

The aim of this study was to evaluate the usefulness of a personalized 3D-printed thyroid model that characterizes a patient’s individual thyroid lesion. The randomized controlled prospective clinical trial (KCT0005069) was designed. Fifty-three of these patients undergoing thyroid surgery were randomly assigned to two groups: with or without a 3D-printed model of their thyroid lesion when obtaining informed consent. We used a U-Net-based deep learning architecture and a mesh-type 3D modeling te

Health InformaticsMedicine
6
Preprint|15 citations·2019
The semantic segmentation approach for normal and pathologic tympanic membrane using deep learning
Jungirl Seok, Jae‐Jin Song, Ja‐Won Koo, Hee Chan Kim, Byung Yoon Choi
bioRxiv (Cold Spring Harbor Laboratory)OA

Abstract Objectives The purpose of this study was to create a deep learning model for the detection and segmentation of major structures of the tympanic membrane. Methods Total 920 tympanic endoscopic images had been stored were obtained, retrospectively. We constructed a detection and segmentation model using Mask R-CNN with ResNet-50 backbone targeting three clinically meaningful structures: (1) tympanic membrane (TM); (2) malleus with side of tympanic membrane; and (3) suspected perforation a

SurgeryMedicine
7
Article|13 citations·2020
Papillary Thyroid Cancers of the Thyroid Isthmus: The Pattern of Nodal Metastasis and the Significance of Extrathyroidal Extension
Jungirl Seok, June Young Choi, Hyeong Won Yu, Young Ho Jung, Soon‐Hyun Ahn, Woo‐Jin Jeong
SJR Q1Annals of Surgical Oncology
Endocrinology, Diabetes and MetabolismMedicine
8
Article|10 citations·2021
Mesh-Type Three-Dimensional (3D) Printing of Human Organs and Tumors: Fast, Cost-Effective, and Personalized Anatomic Modeling of Patient-Oriented Visual Aids
Jungirl Seok, Sungmin Yoon, Chang Hwan Ryu, Junsun Ryu, Seok-Ki Kim, Yuh‐Seog Jung
SJR Q2Applied SciencesOA

Although three-dimensional (3D)-printed anatomic models are not new to medicine, the high costs and lengthy production times entailed have limited their application. Our goal was developing a new and less costly 3D modeling method to depict organ-tumor relations at faster printing speeds. We have devised a method of 3D modeling using tomographic images. Coordinates are extracted at a specified interval, connecting them to create mesh-work replicas. Adjacent constructs are depicted by density var

Biomedical EngineeringEngineering
9
Article|7 citations·2019
The growth rate and the positive prediction of needle biopsy of clinically diagnosed Warthin’s tumor
Jungirl Seok, Woo‐Jin Jeong, Soon‐Hyun Ahn, Young Ho Jung
SJR Q1European Archives of Oto-Rhino-Laryngology
SurgeryMedicine
10
Article|4 citations·2022
Artificial Intelligence for Clinical Research in Voice Disease
Jungirl Seok, Tack‐Kyun Kwon
Journal of The Korean Society of Laryngology Phoniatrics and LogopedicsOA

Diagnosis using voice is non-invasive and can be implemented through various voice recording devices; therefore, it can be used as a screening or diagnostic assistant tool for laryngeal voice disease to help clinicians. The development of artificial intelligence algorithms, such as machine learning, led by the latest deep learning technology, began with a binary classification that distinguishes normal and pathological voices; consequently, it has contributed in improving the accuracy of multi-c

PhysiologyMedicine
11
Article|4 citations·2025
Non-Invasive Jaundice Screening Using AI: Machine Learning Analysis of Sclera and Urine Images
Jungirl Seok, Jae Yeong Kim, Sang Gyune Kim, Young Seok Kim, Jeong‐Ju Yoo
SJR Q1Journal of Clinical MedicineOA

Background: Jaundice commonly indicates liver dysfunction and is traditionally diagnosed via invasive blood tests. Objective: This study aimed to develop an AI-based program utilizing images of sclera and urine for non-invasive jaundice screening and compared its accuracy to that of standard blood tests. Methods: This retrospective study involved patients who underwent liver function and bilirubin tests. Scleral and urine images were collected and processed following a standardized protocol to e

EpidemiologyMedicine
12
Article|3 citations·2020
Singing voice range profile: New objective evaluation methods for voice change after thyroidectomy
Jungirl Seok, Youn Mi Ryu, Seong Ae Jo, Chang Yoon Lee, Yuh‐Seog Jung, Junsun Ryu, Chang Hwan Ryu
SJR Q2Clinical Otolaryngology

Abstract Background After surgery in the thyroid region, patients may present with phonation or singing difficulty, even within their vocal range. We designed a novel voice evaluation method that reflects subjective and objective voice complications of the surgery. Methods This tool recorded patients' voice ranges while singing, which was named the singing voice range profile (singing VRP). Patients were asked to sing “Happy Birthday,” which has a one‐octave scale, at a comfortable tone and inte

PhysiologyMedicine
13
Article|3 citations·2022
Recent Trends in the Incidence of Salivary Gland Malignancies
Jungirl Seok, Eun Hye Park, Kyu-Won Jung, Jae Won Chang
Korean Society for Head and Neck OncologyOA

Due to the low incidence and histologic diversity of salivary gland cancer, analyzing the incidence of salivary gland cancer is necessary to understand the macroscopic aspects. We intend to investigate the international trend of the reported incidence rate of salivary gland cancer. Using the Korea Central Cancer Registry data, the domestic change in the incidence rate was examined. As a result, a significant increasing trend was confirmed, consistent with the United States and Japan trends. The

SurgeryMedicine
14
Preprint|2 citations·2020
Mesh-type 3D Printing of Human Organs and Tumors: Fast, Cost-Effective, and Personalized Anatomic Modeling
Jungirl Seok, Sungmin Yoon, Chang Hwan Ryu, Junsun Ryu, Seok-ki Kim, Yuh‐Seog Jung
Preprints.orgOA

OBJECTIVE: Although 3D-printed anatomic models are not new to medicine, the high costs and lengthy production times entailed have limited their application. Our goal was developing a new and less costly 3D modeling method to depict organ-tumor relations at faster printing speeds. METHODS: We have devised a method of 3D modeling using DICOM images. Coordinates are extracted at a specified interval, connecting them to create mesh-work replicas. Adjacent constructs are depicted by density variation

Biomedical EngineeringEngineering
15
Article|2 citations·2025
Anaplastic and poorly differentiated thyroid carcinomas at intervention sites: implications of track seeding and the importance of follow-up monitoring– report of two cases
Jungirl Seok, Yoo Hyung Kim, Jae‐Kyung Won, Yul Hwangbo, Seog Yun Park, Junsun Ryu
SJR Q1European Archives of Oto-Rhino-Laryngology
Endocrinology, Diabetes and MetabolismMedicine

Research Areas

SurgeryEndocrinology, Diabetes and MetabolismPhysiologyMolecular BiologySensory SystemsOtorhinolaryngology

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