Kyu Sung Lee
Sungkyunkwan University · 医学
研究室紹介
Professor Kyu Sung Lee's research lab specializes in the development of innovative biomedical technologies with a focus on point-of-care diagnostics, urological interventions, and bio-integrated electronic systems. The lab pioneers colorimetric biosensors using gold nanoparticles and localized surface plasmon resonance for rapid detection of viral pathogens such as MERS-CoV, while also advancing minimally invasive treatments for lower urinary tract disorders like overactive bladder and stress urinary incontinence. A key innovation is the creation of stretchable, conformal electronic systems that mimic the dynamic behavior of the urinary bladder, enabling real-time monitoring and potential therapeutic applications. The lab bridges nanotechnology, urology, and bioelectronics to address unmet clinical needs in urological health and infectious disease diagnostics.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15) for detection of Middle East respiratory syndrome coronavirus (MERS-CoV). This platform is able to verify the existence of viral molecules through a localized surface plasmon resonance (LSPR) shift and color changes of AuNPs in the UV-vis wavelength range. We designed a pair of thiol-modified probes at either the 5' end or 3' end to organize complementary base pairs with upstream of the E protein gene (upE) and open reading frames (ORF) 1a on MERS-CoV. The dsDNA of the target and probes forms
This study reveals that combination therapy consisting of alpha1-adrenoceptor antagonists with antimuscarinics represents an effective and relatively safe treatment modality in select patients with OAB coexisting with benign prostatic obstruction.
PURPOSE: Among various intracorporeal lithotriptors, Lithoclast (EMS, Switzerland) has become the widely used tool for the treatment of urinary stones. Recently, the holmium:YAG laser has been used with a wide range of potential urological applications, including intracorporeal lithotripsy of urinary calculi. The purpose of the present study is to compare Lithoclast with holmium:YAG laser lithotripsy in ureteral calculi fragmentation. METHODS: Out of 51 patients with ureteral calculi, 26 underwe
The repeat mid urethral sling for persistent or recurrent stress urinary incontinence has a lower cure rate than the initial sling. However, the retropubic approach tends to have a higher cure rate than the transobturator approach in repeat sling cases.
The tension-free vaginal tape and transobturator vaginal tape inside-out procedures were minimally invasive and similar in operation related morbidity. Transobturator vaginal tape inside-out appeared to be as effective and safe as tension-free vaginal tape for the surgical treatment of stress urinary incontinence in women at 1-year followup.
Underactive bladder or detrusor underactivity (DUA), that is, not being able to micturate, has received less attention with little research and remains unknown or limited on pathological causes and treatments as opposed to overactive bladder, although the syndrome may pose a risk of urinary infections or life-threatening kidney damage. Here, we present an integrated expandable electronic and optoelectronic complex that behaves as a single body with the elastic, time-dynamic urinary bladder with
These results support the hypothesis that OAB in a subgroup of depressed individuals may be associated with altered 5-HT function. It may explain reports of an association between depression and OAB.