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Kyung Bin Joo

Hanyang University · 医学

研究室紹介

Professor Kyung Bin Joo's research lab specializes in rheumatology and musculoskeletal imaging, with a primary focus on ankylosing spondylitis (AS) and related inflammatory conditions. The lab investigates the radiographic progression of spinal and peripheral joint damage, exploring the roles of genetic factors, bone morphogenetic proteins (e.g., BMP6), and signaling pathways such as Wnt/BMP in disease severity. They also examine the impact of conventional disease-modifying antirheumatic drugs (cDMARDs) on radiographic outcomes and evaluate imaging findings in benign soft tissue lesions, such as epidermal inclusion cysts. The lab integrates clinical, radiological, and pathological data to improve understanding of disease mechanisms and treatment responses.

ankylosing spondylitisradiographic progressionBMP6musculoskeletal imagingdisease-modifying antirheumatic drugs

Research Overview

Papers
122
Total Citations
840
Papers (5y)
20
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
20total
2021
2022
2023
2024
2025
Citations per year (5y)
117total
20212022202320242025

Selected Papers

15
1
Article|121 citations·2001
Relationship between sonographic and pathologic findings in epidermal inclusion cysts
Hak Soo Lee, Kyung Bin Joo, Ho‐Taek Song, Yong Soo Kim, Dong Woo Park, Choong Ki Park, Won Mi Lee, Yong Wook Park, Ja Hong Koo, Soon Young Song
SJR Q3Journal of Clinical Ultrasound

PURPOSE: We evaluated the sonographic findings in epidermal inclusion cysts and related them to the pathologic findings. METHODS: We retrospectively reviewed the sonograms and pathology specimens of 24 patients with pathologically proven epidermal inclusion cysts. We evaluated the lesions for shape, size, internal echogenicity, posterior sound enhancement, and presence of color Doppler signals. We classified the masses into 5 sonographic types according to their internal echogenicity. The relati

SurgeryMedicine
2
letter|95 citations·2015
ERAP2 is associated with ankylosing spondylitis in HLA-B27-positive and HLA-B27-negative patients
Philip C. Robinson, M. E. Costello, Paul Leo, Linda A. Bradbury, Kelly Hollis, Adrián Cortés, Seunghun Lee, Kyung Bin Joo, Seung Cheol Shim, Michael H. Weisman, Michael M. Ward, Xiaodong Zhou
SJR Q1Annals of the Rheumatic DiseasesOA
RheumatologyMedicine
3
Article|88 citations·2020
Tumour necrosis factor inhibitors slow radiographic progression in patients with ankylosing spondylitis: 18-year real-world evidence
Bon San Koo, Ji Seon Oh, Seo Young Park, Ji Hui Shin, Ga Young Ahn, Seunghun Lee, Kyung Bin Joo, Tae‐Hwan Kim
SJR Q1Annals of the Rheumatic DiseasesOA
RheumatologyMedicine
4
Article|46 citations·2001
Radiologic Changes of Cervical Spine in Ankylosing Spondylitis
H.-S. Lee, T.-H. Kim, Hye-Ryeon Yun, Yong-Wook Park, S.S. Jung, Sang‐Cheol Bae, Kyung Bin Joo, S.Y. Kim
SJR Q2Clinical Rheumatology
RheumatologyMedicine
5
Article|46 citations·2002
Tuberculous Pleural Effusion: New Pulmonary Lesions during Treatment
Yo Won Choi, Seok Chol Jeon, Heung Seok Seo, Choong Ki Park, Sung Soo Park, Chang Kok Hahm, Kyung Bin Joo
SJR Q1Radiology

New lung lesions that develop during medication for tuberculous pleural effusion should be considered a transient worsening that ultimately improves with continuation of medication.

Pulmonary and Respiratory MedicineMedicine
6
Article|29 citations·2012
Prevalence and Risk Factors of Anterior Atlantoaxial Subluxation in Ankylosing Spondylitis
JI-SEON LEE, Seunghun Lee, So‐Young Bang, Kyung Soo Choi, Kyung Bin Joo, Yong-Bum Kim, Il‐Hoon Sung, Tae‐Hwan Kim
SJR Q1The Journal of RheumatologyOA

OBJECTIVE: In ankylosing spondylitis (AS), the cervical spine, like other sections of the spine and sacroiliac joints, is vulnerable during the disease process. Atlantoaxial subluxation (AAS) has been studied in connection with AS, but its risk factors and progression have not been clarified. Therefore, this study assessed the prevalence and risk factors of AAS in patients with AS. METHODS: A total of 819 patients with AS who fulfilled the modified New York criteria and were examined with a full

RheumatologyMedicine
7
Article|29 citations·2014
Bone Morphogenetic Protein 6 Polymorphisms Are Associated with Radiographic Progression in Ankylosing Spondylitis
Young Bin Joo, So‐Young Bang, Tae‐Hwan Kim, Seung Cheol Shim, Seunghun Lee, Kyung Bin Joo, Jong Heon Kim, Hye Joon Min, Proton Rahman, Robert D. Inman
SJR Q1PLoS ONEOA

This is the first study to demonstrate that BMP6 is associated with radiographic severity in AS, supporting the role wingless-type like/BMP pathway on radiographic progression in AS.

RheumatologyMedicine
8
Article|25 citations·2001
Ca3Ga2Ge4O14 (CGG)-type Sr3Nb0.95Ga3.083Si2O14 single crystal grown by the Czochralski method for piezoelectric applications
Il Hyoung Jung, Yong Ho Kang, Kyung Bin Joo, Akira Yoshikawa, Tsuguo Fukuda, Yong Ho Auh
SJR Q2Materials Letters
Biomedical EngineeringEngineering
9
Article|20 citations·2022
Clinical and genetic factors associated with radiographic damage in patients with ankylosing spondylitis
Bora Nam, Sungsin Jo, So‐Young Bang, Young‐Ho Park, Ji Hui Shin, Ye‐Soo Park, Seunghun Lee, Kyung Bin Joo, Tae‐Hwan Kim
SJR Q1Annals of the Rheumatic DiseasesOA

This study identified clinical and genetic factors that contributed to better understanding of the pathogenesis and biology associated with radiographic damage in AS.

RheumatologyMedicine
10
Article|18 citations·2020
Conventional disease-modifying antirheumatic drugs therapy may not slow spinal radiographic progression in ankylosing spondylitis: results from an 18-year longitudinal dataset
Tae-Han Lee, Bon San Koo, Bora Nam, Ji Seon Oh, Seo Young Park, Seunghun Lee, Kyung Bin Joo, Tae‐Hwan Kim
SJR Q1Therapeutic Advances in Musculoskeletal DiseaseOA

OBJECTIVES: The clinical benefit of conventional disease-modifying antirheumatic drugs (cDMARDs) for treating ankylosing spondylitis (AS) is generally limited to improvements in peripheral arthritis. However, cDMARDs could be conditionally considered as alternatives to established drugs for improving axial manifestations in exceptional circumstances. However, there are few studies of the impact of cDMARDs on radiographic progression outcomes. Therefore, we investigated the effectiveness of cDMAR

RheumatologyMedicine
11
Article|17 citations·2022
A pilot study on deep learning-based grading of corners of vertebral bodies for assessment of radiographic progression in patients with ankylosing spondylitis
Bon San Koo, Jae‐Joon Lee, JaeWoo Jung, Chang Ho Kang, Kyung Bin Joo, Tae‐Hwan Kim, Seunghun Lee
SJR Q1Therapeutic Advances in Musculoskeletal DiseaseOA

Background: Radiographs are widely used to evaluate radiographic progression with modified stoke ankylosing spondylitis spinal score (mSASSS). Objective: This pilot study aimed to develop a deep learning model for grading the corners of the cervical and lumbar vertebral bodies for computer-aided detection of mSASSS in patients with ankylosing spondylitis (AS). Methods: Digital radiographic examination of the spine was performed using Discovery XR656 (GE Healthcare) and Digital Diagnost (Philips)

Biomedical EngineeringEngineering
12
Article|17 citations·2014
The presence of peripheral arthritis delays spinal radiographic progression in ankylosing spondylitis: Observation Study of the Korean Spondyloarthropathy Registry
Tae‐Jong Kim, Seunghun Lee, Kyung Bin Joo, Dong-Jin Park, Yong-Wook Park, Shin‐Seok Lee, Tae-Hwan Kim
SJR Q1Lara D. VeekenOA

OBJECTIVES: The aim of this study was to determine whether the presence of peripheral arthritis can affect radiographic structural damage in patients with AS. METHODS: A total of 915 subjects comprising 363 patients with a history of peripheral arthritis and 552 patients without a history of peripheral arthritis obtained from the Observation Study of the Korean SpA Registry (OSKAR) were analysed looking at the relationship of peripheral arthritis history in a cross-sectional survey as well as th

RheumatologyMedicine
13
Article|15 citations·2011
Acute Retropharyngeal Calcific Tendinitis in an Unusual Location: a Case Report in a Patient with Rheumatoid Arthritis and Atlantoaxial Subluxation
Seunghun Lee, Kyung Bin Joo, Kyu Hoon Lee, Wan-Sik Uhm
SJR Q1Korean Journal of RadiologyOA

Retropharyngeal calcific tendinitis is defined as inflammation of the longus colli muscle and is caused by the deposition of calcium hydroxyapatite crystals, which usually involves the superior oblique fibers of the longus colli muscle from C1-3. Diagnosis is usually made by detecting amorphous calcification and prevertebral soft tissue swelling on radiograph, CT or MRI. In this report, we introduce a case of this disease which was misdiagnosed as a retropharyngeal tuberculous abscess, or a musc

Infectious DiseasesMedicine
14
Article|15 citations·2013
HLA-B27 homozygosity has no influence on radiographic damage in ankylosing spondylitis: Observation Study of Korean spondyloArthropathy Registry (OSKAR) data
Tae‐Jong Kim, Il‐Hoon Sung, Seunghun Lee, Kyung Bin Joo, Jung Hyun Choi, Dong-Jin Park, Yong-Wook Park, Shin‐Seok Lee, Tae‐Hwan Kim
SJR Q2Joint Bone Spine
RheumatologyMedicine
15
Article|15 citations·2022
Age-stratified trends in the progression of spinal radiographic damage in patients with ankylosing spondylitis: a longitudinal study
Tae-Han Lee, Bon San Koo, Bora Nam, Yun Jin Kim, Donghee Son, Seunghun Lee, Kyung Bin Joo, Tae‐Hwan Kim
SJR Q1Therapeutic Advances in Musculoskeletal DiseaseOA

Objective: The objective of this study was to investigate spinal radiographic progression in specific age ranges of ankylosing spondylitis (AS) patients. Methods: Longitudinal data for 1125 AS patients at a single hospital from 2000 to 2018 were retrospectively reviewed. Radiographic intervals were obtained from patients with consecutive spinal radiographs. The radiographic progression rate was defined as the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) change per year within each

RheumatologyMedicine

Research Areas

RheumatologySurgeryPulmonary and Respiratory MedicineBiomedical EngineeringGeneticsPublic Health, Environmental and Occupational Health

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