Kyung-eun Han
Ewha Womans University · 医学
研究室紹介
Professor Kyung-eun Han's research lab specializes in ophthalmic translational medicine, focusing on corneal diseases, ocular surface disorders, and regenerative therapies. The lab investigates genetic factors in corneal dystrophies, such as GCD2, and explores novel treatments for corneal injuries using human-derived biological agents like amniotic membrane and serum. Key research directions include the pathogenesis of corneal neovascularization, the development of safe and effective electrosurgical techniques for lymphangiectasis, and the preclinical evaluation of regenerative therapies in animal models of alkali burns. The lab emphasizes precision medicine through genetic analysis and longitudinal clinical evaluation.
Research Overview
Research Output Trend
Figures are computed from collected data and may differ slightly.
Selected Papers
15This study provides data on the prevalence and independent risk factors for clinically significant exodeviation and esodeviation in a representative population of children and adolescents in South Korea.
Perfect treatment of exacerbation after corneal surface ablation does not exist until now. To prevent exacerbation, refractive surgeons must do a careful preoperative examination of candidates in refractive surgeries.
GCD2 heterozygotes have extremely varied phenotypes between individual patients. However phenotypes were broadly consistent within families, suggesting that the observed variable expressivity might be regulated by other genetic factors that could influence the abundance of TGFBIp or the function of the pathway. From a clinical perspective, our data also highlighted that genetic analysis and meticulous slit-lamp examination in both eyes at multiple time intervals is necessary.
High-frequency radio wave electrosurgery may be a safe, quick, and effective modality for the treatment of symptomatic lymphangiectasis patients.
No author has a financial or proprietary interest in any material or method mentioned.
<b>Purpose:</b> To compare the therapeutic effects of human derivatives in a mouse alkali burn model. <b>Methods:</b> The right eyes of mice were injured using NaOH. After alkali injury, one of the following agents was topically administered for 7 d: human amniotic membrane (hAM) suspension, human umbilical cord serum (hUCS), and human peripheral blood serum (hPBS), or saline. The epithelial defect areas on days 1, 2, and 3 degrees of opacity on days 2, 3, and 7, and corneal neovascularization (
The disappearance of granular deposits in GCD1 and GCD2 could be interpreted as evidence of drop-off phenomena with recurrent corneal erosion. With drop off of the deposits, various configurations and morphological changes of corneal deposits can occur in these corneal dystrophies.
No author has a financial or proprietary interest in any material or method mentioned.
There were no differences on epithelial wound healing comparing these two different fluoroquinolones at the incision site of cataract surgery.
<i>Purpose</i>: To report a new surgical procedure using biodegradable collagen matrix (Ologen) implantation with conjunctival flap for reconstruction of scleromalacia after periocular surgery. <i>Methods</i>: A total of 26 areas of 25 eyes in 25 patients were included. We divided all eyes according to the preoperative extent of calcified plaque or scleral defect as follows: small, large, and large and severe. Morphologic outcomes were graded from 0 to 7, with higher scores indicating worse cosm
Diabetic patients can experience more prominent changes after surgery and these changes were accompanied by an increase of several tear cytokines.