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Kyung-Min Kuo

Korea University · 医学

研究室紹介

Professor Kyung-Min Kuo's research lab specializes in occupational and environmental health, with a primary focus on the long-term health impacts of exposure to carcinogenic substances such as formaldehyde, asbestos, and other industrial pollutants. The lab conducts systematic reviews and meta-analyses to evaluate the epidemiological associations between environmental and occupational exposures and various cancers, including lung, mesothelioma, and colorectal cancers. A key research direction involves predicting future disease trends using statistical models, such as age-period-cohort models, particularly for diseases with long latency periods like malignant mesothelioma. The lab also investigates long-term treatment outcomes in chronic diseases, such as hepatitis B, comparing the efficacy of antiviral therapies like entecavir and tenofovir.

occupational healthasbestos exposurecancer epidemiologysystematic reviewmeta-analysis

Research Overview

Papers
39
Total Citations
537
Papers (5y)
11
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
11total
2022
2023
2024
2025
2026
Citations per year (5y)
50total
20222023202420252026

Selected Papers

15
1
Review|64 citations·2020
Occupational exposure to formaldehyde and risk of lung cancer: A systematic review and meta‐analysis
Kyeongmin Kwak, Domyung Paek, Jong‐Tae Park
SJR Q1American Journal of Industrial Medicine

BACKGROUND: Formaldehyde exposure is associated with nasopharyngeal cancer and leukemia. Previously-described links between formaldehyde exposure and lung cancer have been weak and inconsistent. We performed a systematic review and meta-analysis to evaluate quantitatively the association between formaldehyde exposure and lung cancer. METHODS: We searched for articles on occupational formaldehyde exposure and lung cancer in PubMed, EMBASE, Web of Science, and CINAHL databases. In total, 32 articl

Health, Toxicology and MutagenesisEnvironmental Science
2
Article|49 citations·2017
Comparison of the long-term efficacy between entecavir and tenofovir in treatment- naïve chronic hepatitis B patients
Ji Won Park, Kyeongmin Kwak, Sung Eun Kim, Myoung Kuk Jang, Ki Tae Suk, Dong Joon Kim, Sang Hoon Park, Myung Seok Lee, Hyoung Su Kim, Choong Kee Park
SJR Q2BMC GastroenterologyOA

BACKGROUND: There have been limited studies directly comparing the long-term efficacy between entecavir (ETV) and tenofovir disoproxil fumarate (TDF). This study was aimed to compare the long-term efficacy between them in treatment-naïve chronic hepatitis B (CHB). METHODS: Out of 345 CHB patients who received first line therapy with ETV (n = 200) or TDF (n = 145) in a cohort, 210 patients were analyzed using propensity score matching, at a ratio of 1:1. RESULTS: IU/mL, P = 0.559). At month 12, b

EpidemiologyMedicine
3
Review|49 citations·2021
Environmental exposure to asbestos and the risk of lung cancer: a systematic review and meta-analysis
Kyeongmin Kwak, Dongmug Kang, Domyung Paek
SJR Q1Occupational and Environmental Medicine

Asbestos is a carcinogen associated with lung cancer, but few studies have examined the increased risk of lung cancer due to environmental asbestos exposure. We performed a systematic review and meta-analysis to evaluate the association between environmental asbestos exposure and lung cancer. We searched for articles on non-occupational or environmental asbestos exposure and lung cancer in PubMed, EMBASE, CINAHL and Web of Science databases. Our review included 15 studies, and except studies on

Pulmonary and Respiratory MedicineMedicine
4
Article|38 citations·2015
The effect of organisational system on self-rated depression in a panel of male municipal firefighters
Se‐Jin An, Yun Kyung Chung, Bong Hyun Kim, Kyeongmin Kwak, JunSeok Son, Jung‐Wan Koo, Young‐Su Ju, Young‐Jun Kwon
SJR Q2Annals of Occupational and Environmental MedicineOA

Although the healthy worker effect may be involved, job stress based on perceptions of organisational system was a strong risk factor for depression. A comprehensive approach should be considered that encompasses social issues when assessing or mental health in high-risk groups, as well as the practical issue of physiochemical hazards.

Occupational TherapyHealth Professions
5
Article|30 citations·2017
Estimated future incidence of malignant mesothelioma in South Korea: Projection from 2014 to 2033
Kyeongmin Kwak, Domyung Paek, Seung-Sik Hwang, Young‐Su Ju
SJR Q1PLoS ONEOA

Malignant mesothelioma is a malignant tumor on the pleura or the peritoneum caused mostly by asbestos. Although asbestos is not currently used in South Korea, the incidence of mesothelioma is increasing due to its long latent period. This study predicted the incidence of malignant mesothelioma in South Korea over the next 20 years using an age-period-cohort (APC) model. Data regarding mesothelioma incidence from 1994-2013 were acquired from the Korea Central Cancer Registry (KCCR). Demographic d

Pulmonary and Respiratory MedicineMedicine
6
Article|27 citations·2016
The effect of aircraft noise on sleep disturbance among the residents near a civilian airport: a cross-sectional study
Kyeongmin Kwak, Young‐Su Ju, Young‐Jun Kwon, Yun Kyung Chung, Bong Kyu Kim, Hyunjoo Kim, Kanwoo Youn
SJR Q2Annals of Occupational and Environmental MedicineOA

The prevalence of insomnia and daytime hypersomnia was higher in the aircraft noise exposure group, as compared to the control group. Further study is deemed necessary in order to clarify the causal relationship.

Speech and HearingHealth Professions
7
Review|27 citations·2019
Exposure to asbestos and the risk of colorectal cancer mortality: a systematic review and meta-analysis
Kyeongmin Kwak, Domyung Paek, Kyung Ehi Zoh
SJR Q1Occupational and Environmental Medicine

Asbestos exposure is associated with mesothelioma and cancer of the lung, larynx and ovary. However, the association between asbestos exposure and colorectal cancer is controversial despite several systematic reviews of the literature, including a number of meta-analyses. We performed a systematic review and meta-analysis to evaluate quantitatively the association between exposure to asbestos and colorectal cancer. We searched for articles on occupational asbestos exposure and colorectal cancer

Pulmonary and Respiratory MedicineMedicine
8
Article|17 citations·2020
Association between Shift Work and Neurocognitive Function among Firefighters in South Korea: A Prospective before–after Study
Kyeongmin Kwak, Bong-Kyu Kim, Tae Won Jang, Chang Sun Sim, Yeon‐Soon Ahn, Kyeong‐Sook Choi, Kyoung Sook Jeong
SJR Q2International Journal of Environmental Research and Public HealthOA

Background: Recent research indicates that shift work is associated with neurocognitive function. However, studies that examine the association between shift work and neurocognitive function in firefighters have not yet been performed. We examined the effect of shift work on neurocognitive function in firefighters by measuring and comparing neurocognitive function before and after night shift. Methods: 352 firefighters from eight fire stations in South Korea were included in this study. We perfo

Occupational TherapyHealth Professions
9
Article|14 citations·2022
Influence of temperature and precipitation on the incidence of hepatitis A in Seoul, Republic of Korea: a time series analysis using distributed lag linear and non-linear model
Kiook Baek, Jonghyuk Choi, Jong‐Tae Park, Kyeongmin Kwak
SJR Q1International Journal of Biometeorology
Health, Toxicology and MutagenesisEnvironmental Science
10
Article|13 citations·2021
Future Incidence of Malignant Mesothelioma in South Korea: Updated Projection to 2038
Kyeongmin Kwak, Sung‐Il Cho, Domyung Paek
SJR Q2International Journal of Environmental Research and Public HealthOA

Malignant mesothelioma (MM) is a cancer that is largely caused by exposure to asbestos. Although asbestos is no longer used in South Korea, the incidence of MM continues to increase due to its long latent period. We aimed to update the previous prediction of MM incidence until 2038. We predicted the incidence of MM over the next 20 years (2019-2038) in South Korea using Møller's age-period-cohort (APC) model and a Poisson regression model based on asbestos consumption. The APC model predicted th

Pulmonary and Respiratory MedicineMedicine
11
Article|11 citations·2021
Association of Urinary Bisphenols Concentration with Asthma in Korean Adolescents: Data from the Third Korean National Environmental Health Survey
Kiook Baek, Jong‐Tae Park, Kyeongmin Kwak
SJR Q1ToxicsOA

The effects of bisphenol A (BPA) on asthma have been reported in various in vitro, animal, and human epidemiologic studies. However, epidemiological studies on the effects of bisphenol S (BPS) and bisphenol F (BPF), which are substitutes of BPA, on asthma are lacking. The purpose of this study was to identify the association between BPA, BPS, and BPF and asthma. An asthma-related questionnaire; urinary BPA, BPS, BPF; and the possible confounders were analyzed among 922 adolescents aged 12–17 yea

Health, Toxicology and MutagenesisEnvironmental Science
12
Article|10 citations·2021
Incidence of Cancer and Asbestos-Related Diseases among Residents Living near Abandoned Asbestos Mines in South Korea: A Retrospective Cohort Study Using National Health Insurance Database
Kyeongmin Kwak, Kyung Ehi Zoh, Domyung Paek
SJR Q2International Journal of Environmental Research and Public HealthOA

The use of asbestos has been banned since 2009 in South Korea. However, there is still a risk of exposure to environmental asbestos originating from abandoned asbestos mines. We constructed a retrospective dynamic cohort using the National Health Insurance Database of South Korea. We determined the risk of developing asbestos-related diseases (ARDs) among residents living near asbestos mines compared with those living in the control area and the general population. The risks of asbestosis (adjus

Pulmonary and Respiratory MedicineMedicine
13
Article|9 citations·2018
Acute toxic encephalopathy induced by occupational exposure to 1,2-dichloropropane
Kyeongmin Kwak, Kyoung Sook Jeong, Dong Hoon Shin, Won-Jun Choi, Hyun Soo Kim, Seong‐Kyu Kang
SJR Q2Industrial HealthOA

1,2-Dichloropropane (1,2-DCP) is used widely in Korea as a substitute for trichloroethylene or methylene chloride. Some companies mistakenly consider that 1,2-DCP is an eco-friendly detergent because its use is not regulated, but 1,2-DCP is known to inhibit the central nervous system in animals; a few cases of accidental exposure have been reported in humans. We present a case of acute encephalopathy caused by exposure to 1,2-DCP. A 41 yr-old male presented with dizziness, headache, and diplopia

NeurologyMedicine
14
Article|8 citations·2020
Association Between Carbon Monoxide Intoxication and Incidence of Ischemic Stroke: A Retrospective Nested Case-Control Study in South Korea
Kyeongmin Kwak, Min Kim, Won-Jun Choi, Young‐Su Ju, Jong‐Tae Park
SJR Q1Journal of Stroke and Cerebrovascular Diseases
Molecular BiologyBiochemistry, Genetics and Molecular Biology
15
Article|8 citations·2024
Predicted Cervical Cancer Prevention: Impact of National HPV Vaccination Program on Young Women in South Korea
Kyeongmin Kwak, Seung-Sik Hwang
SJR Q1Cancer Research and TreatmentOA

PURPOSE: This study aimed to evaluate the effectiveness of the national human papillomavirus (HPV) vaccination program of South Korea among its entire female population, particularly among younger age groups. MATERIALS AND METHODS: We first predicted the incidence of cervical cancer over the next 20 years (2021-2040) using the Nordpred package based on Møller's age-period-cohort model under several scenarios for the national HPV vaccination program. We calculated the potential impact fractions a

EpidemiologyMedicine

Research Areas

Pulmonary and Respiratory MedicineHealth, Toxicology and MutagenesisEpidemiologyMolecular BiologyOccupational TherapyPhysiology

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