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Lee, Dong Yeon

Seoul National University · 医学

研究室紹介

Professor Lee Dong Yeon's research lab specializes in musculoskeletal and vascular imaging, with a focus on improving diagnostic accuracy and understanding the pathophysiology of foot and ankle disorders. The lab investigates advanced medical imaging techniques such as SPECT/CT and MRI for evaluating bone, soft tissue, and joint pathologies, while also exploring hemodynamic and cellular mechanisms in conditions like diabetic foot ulcers and congenital pseudarthrosis. A key research direction involves the biological and functional analysis of progenitor cells and fibroblastic cells to elucidate disease mechanisms and enhance therapeutic strategies.

medical imagingdiabetic footperipheral arterial diseasefoot kinematicsosteoblast differentiation

Research Overview

Papers
179
Total Citations
2,054
Papers (5y)
52
Primary Field
医学

Research Output Trend

Figures are computed from collected data and may differ slightly.

Publications per year (5y)
52total
2022
2023
2024
2025
2026
Citations per year (5y)
140total
20222023202420252026

Selected Papers

15
1
Article|148 citations·2008
Mobilization of endothelial progenitor cells in fracture healing and distraction osteogenesis
Dong Yeon Lee, Tae‐Joon Cho, Jin A Kim, Hyeran Lee, Won Joon Yoo, Chin Youb Chung, In Ho Choi
SJR Q1Bone
SurgeryMedicine
2
Article|56 citations·2019
Flatfoot deformity affected the kinematics of the foot and ankle in proportion to the severity of deformity
Hyuck Soo Shin, Jae Hee Lee, Eo Jin Kim, Min Gyu Kyung, Hyo Jeong Yoo, Dong Yeon Lee
SJR Q1Gait & Posture
Biomedical EngineeringEngineering
3
Article|55 citations·2015
Comparison of SPECT/CT and MRI in Diagnosing Symptomatic Lesions in Ankle and Foot Pain Patients: Diagnostic Performance and Relation to Lesion Type
Seunggyun Ha, Sung Hwan Hong, Jin Chul Paeng, Dong Yeon Lee, Dong Yeon Lee, Gi Jeong Cheon, Amitabh Arya, June-Key Chung, Dong Soo Lee, Dong Soo Lee, Keon Wook Kang
SJR Q1PLoS ONEOA

PURPOSE: The purpose of this study was to compare the diagnostic performance of SPECT/CT and MRI in patients with ankle and foot pain, with regard to the lesion types. MATERIALS AND METHODS: Fifty consecutive patients with ankle and foot pain, who underwent 99mTc-MDP SPECT/CT and MRI, were retrospectively enrolled in this study. Symptomatic lesions were determined based on clinical examination and response to treatment. On MRI and SPECT/CT, detected lesions were classified as bone, ligament/tend

Orthopedics and Sports MedicineMedicine
4
Article|52 citations·2014
Repeatability of a multi‐segment foot model with a 15‐marker set in healthy adults
Sang Gyo Seo, Dong Yeon Lee, Hyuk Ju Moon, Sung Ju Kim, Jihyeung Kim, Kyoung Min Lee, Chin Youb Chung, In Ho Choi
SJR Q2Journal of Foot and Ankle ResearchOA

BACKGROUND: Several 3D multi-segment foot models (MFMs) have been introduced for the in vivo analysis of dynamic foot kinematics. However, reproducibility of a model should be checked and ascertained before clinical utilization of a MFM. The purpose of this study was to determine the reliability of recently introduced MFM with a 15-marker set by assessing the participant's stride-to-stride (intra-session) and visit-to-revisit (inter-session) repeatability. METHODS: Twenty healthy adults with a m

Biomedical EngineeringEngineering
5
Article|50 citations·2013
Negative-pressure wound therapy induces endothelial progenitor cell mobilization in diabetic patients with foot infection or skin defects
Sang Gyo Seo, Ji Hyun Yeo, Ji Hye Kim, Ji-Beom Kim, Tae‐Joon Cho, Dong Yeon Lee
SJR Q1Experimental & Molecular MedicineOA

Non healing chronic wounds are difficult to treat in patients with diabetes and can result in severe medical problems for these patients and for society. Negative-pressure wound therapy (NPWT) has been adopted to treat intractable chronic wounds and has been reported to be effective. However, the mechanisms underlying the effects of this treatment have not been elucidated. To assess the vasculogenic effect of NPWT, we evaluated the systemic mobilization of endothelial progenitor cells (EPCs) dur

Biomedical EngineeringEngineering
6
Article|50 citations·2009
Distraction osteogenesis induces endothelial progenitor cell mobilization without inflammatory response in man
Dong Yeon Lee, Tae‐Joon Cho, Hyeran Lee, Moon Seok Park, Won Joon Yoo, Chin Youb Chung, In Ho Choi
SJR Q1Bone
SurgeryMedicine
7
Article|39 citations·2010
Application of the Ilizarov Technique to the Correction of Neurologic Equinocavovarus Foot Deformity
Dong Yeon Lee, In Ho Choi, Won Joon Yoo, Soong Joon Lee, Tae‐Joon Cho
SJR Q1Clinical Orthopaedics and Related Research

Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

Orthopedics and Sports MedicineMedicine
8
Article|39 citations·2012
Photoplethysmography and Continuous-Wave Doppler Ultrasound as a Complementary Test to Ankle–Brachial Index in Detection of Stenotic Peripheral Arterial Disease
Du Hyun Ro, Hyuk Ju Moon, Ji Hyeung Kim, Kyoung Min Lee, Sung Ju Kim, Dong Yeon Lee
SJR Q2Angiology

PURPOSE: We evaluated the sensitivity and specificity of ankle-brachial index (ABI), photoplethysmography (PPG), and continuous-wave Doppler ultrasound (CWD) in the detection of anatomically stenotic peripheral arterial disease (PAD). METHODS: Ninety-seven patients (194 legs) patients who had coincidentally undergone computed tomography angiography (CTA), ABI, PPG, and CWD for the evaluation of PAD were retrospectively reviewed. Sensitivity and specificity were measured. RESULTS: Among 194 legs,

SurgeryMedicine
9
Article|35 citations·2011
Disturbed Osteoblastic Differentiation of Fibrous Hamartoma Cell from Congenital Pseudarthrosis of the Tibia Associated with Neurofibromatosis Type I
Dong Yeon Lee, Tae‐Joon Cho, Hyeran Lee, Kang Lee, Hyuk Joo Moon, Moon Seok Park, Won Joon Yoo, Chin Youb Chung, In Ho Choi
SJR Q1Clinics in Orthopedic SurgeryOA

BACKGROUND: Fibrous hamartoma is the key pathology of congenital pseudarthrosis of the tibia (CPT), which was shown to have low osteogenicity and high osteoclastogenicity. This study further investigated the mechanism of impaired osteoblastic differentiation of fibrous hamartoma cells. METHODS: Fibroblast-like cells were obtained from enzymatically dissociated fibrous hamartomas of 11 patients with CPT associated with neurofibromatosis type I (NF1). Periosteal cells were also obtained from the d

RheumatologyMedicine
10
Article|35 citations·2006
Clinical and Radiological Manifestations of Osteogenesis Imperfecta Type V
Dong Yeon Lee, Tae‐Joon Cho, In Ho Choi, Chin Youb Chung, Won Joon Yoo, Ji Hyung Kim, Yong Koo Park
SJR Q2Journal of Korean Medical ScienceOA

We reviewed clinical manifestation of 12 patients from three Korean families. They showed mild to moderate bone fragility, and suggested an autosomal dominant inheritance pattern. Significant intrafamilial phenotype variability was obvious. Clinical, radiological, and histopathologic characteristics that distinguished this subtype from others include ossification of interosseous membrane of the forearm with radial head dislocation, hyperplastic callus formation, no evidence of type I collagenopa

GeneticsBiochemistry, Genetics and Molecular Biology
11
Article|34 citations·2017
Comparison of Multisegmental Foot and Ankle Motion Between Total Ankle Replacement and Ankle Arthrodesis in Adults
Sang Gyo Seo, Eo Jin Kim, Doo Jae Lee, Doo Jae Lee, Kee Jeong Bae, Kyoung Min Lee, Dong Yeon Lee, Dong Yeon Lee
SJR Q1Foot & Ankle International

BACKGROUND: Total ankle replacement (TAR) and ankle arthrodesis (AA) are usually performed for severe ankle arthritis. We compared postoperative foot segmental motion during gait in patients treated with TAR and AA. METHODS: Gait analysis was performed in 17 and 7 patients undergoing TAR and AA, respectively. Subjects were evaluated using a 3-dimensional multisegmental foot model with 15 markers. Temporal gait parameters were calculated. The maximum and minimum values and the differences in hall

Orthopedics and Sports MedicineMedicine
12
Article|34 citations·2014
Correlation Between Static Radiographic Measurements and Intersegmental Angular Measurements During Gait Using a Multisegment Foot Model
Dong Yeon Lee, Sang Gyo Seo, Eo Jin Kim, Sung Ju Kim, Kyoung Min Lee, Daniel C. Farber, Chin Youb Chung, In Ho Choi
SJR Q1Foot & Ankle International

BACKGROUND: Radiographic examination is a widely used evaluation method in the orthopedic clinic. However, conventional radiography alone does not reflect the dynamic changes between foot and ankle segments during gait. Multiple 3-dimensional multisegment foot models (3D MFMs) have been introduced to evaluate intersegmental motion of the foot. In this study, we evaluated the correlation between static radiographic indices and intersegmental foot motion indices. METHODS: One hundred twenty-five f

Biomedical EngineeringEngineering
13
Article|30 citations·2016
Inter-segmental motions of the foot in healthy adults: Gender difference
Dong Yeon Lee, Sang Gyo Seo, Eo Jin Kim, Sung Ju Kim, Kyoung Min Lee, In Ho Choi
SJR Q2Journal of Orthopaedic Science
Biomedical EngineeringEngineering
14
Article|25 citations·2020
Inter‐segmental foot kinematics during gait in elderly females according to the severity of hallux valgus
Eo Jin Kim, Hyuck Soo Shin, Naoko Takatori, Hyo Jeong Yoo, Yun Jae Cho, Won Joon Yoo, Dong Yeon Lee
SJR Q1Journal of Orthopaedic Research®OA

The objective of this study was to find the effect of hallux valgus (HV) deformity on the inter-segmental motion of the foot using an MFM with a 15-marker set (DuPont Foot Model, DuFM) in comparison with age and sex controlled healthy adults. Fifty-eight female symptomatic HV patients and 50 female asymptomatic older female volunteers were included in this study. According to the radiographic hallux valgus angle (HVA), the study population was divided into severe HV (SHV, HVA ≥ 40°, n = 25), mod

Orthopedics and Sports MedicineMedicine
15
Article|24 citations·2016
Foot and Ankle Function at Maturity After Ilizarov Treatment for Atrophic-Type Congenital Pseudarthrosis of the Tibia
Sang Gyo Seo, Dong Yeon Lee, Yeon Soo Kim, Won Joon Yoo, Tae‐Joon Cho, In Ho Choi
SJR Q1Journal of Bone and Joint Surgery

BACKGROUND: The purpose of this study was to evaluate clinical outcomes and the biomechanical function of the foot and ankle at skeletal maturity of patients treated for atrophic-type congenital pseudarthrosis of the tibia (CPT) compared with healthy young adult controls. METHODS: Twenty-four patients (mean age of 19.1 years) who had undergone Ilizarov treatment for unilateral atrophic-type CPT were compared with twenty-four controls (mean age of 19.6 years). All participants were evaluated usin

EpidemiologyMedicine

Research Areas

Orthopedics and Sports MedicineBiomedical EngineeringSurgeryEndocrinology, Diabetes and MetabolismComputational MechanicsEpidemiology

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